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A programme for the construction of a lambda phage
A programme for the construction of a lambda phage

... biologists working on more complex systems. This review will present a simple account of the key steps in the lytic and lysogenic pathways, with emphasis on the control mechanisms governing co-ordination and commitment to a particular pathway. THE LAMBDA GENOME ...
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... by the optimization of hydrogen bond formation in DNA (A-T and C-G) or in RNA (AU and C-G). Two polynucleotide strands, or regions thereof, in which all the nucleotides form such base pairs are said to be complementary. In achieving complementarity, each strand of DNA can serve as a template for syn ...
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... where the temperature of the hair follicles is high, the gene product is inactive or less active, resulting in less pigment. However, on the points (ears, nose, feet and tail), where the temperature is slightly cooler, the mutant tyrosinase is active and pigmentation is darker. The difference betwee ...
Leukaemia Section ins(9;4)(q33;q12q25) Atlas of Genetics and Cytogenetics in Oncology and Haematology
Leukaemia Section ins(9;4)(q33;q12q25) Atlas of Genetics and Cytogenetics in Oncology and Haematology

... assembly (Fong et al., 2009); critical for centrosomal localization of dynein throughout the cell cycle (Lee and Rhee, 2010). CDK5RAP2-knockdown cells have increased resistance to paclitaxel and doxorubicin (Zhang et al., 2009). Homozygous mutations in CDK5RAP2 can cause microcephaly (Bond et al., ...
The RNAi mechanism
The RNAi mechanism

... • Because of DNA Sequencing many genes are known before their function is understood. • In reverse genetics, researchers engineer a change or disruption and then observe the effect to determine the function of the gene. • Previously this was done by site-directedmutagenesis or by gene knockout. From ...
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... incorporated into nucleotides of the DNA strands Each daughter cell was fed on normal nitrogen thus any new nucleotides formed would contain normal nitrogen. On replication, therefore, each replicated strand was normal. With cell division, a normal chromosome goes to one daughter cell and a labelled ...
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... on mitochondria to NLRP3 on the endoplasmic reticulum. Therefore, in addition to direct activation of NLRP3, the creation of optimal sites for signal transduction by microtubules is required for activation of the entire NLRP3 inflammasome. ...
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Cell Continuity - The Physics Teacher

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... 20) Which of the following is a feature of plant cell division that distinguishes it from animal cell division? A) A cell plate forms. B) Four new cells (rather than two) are produced per mitotic division. C) Cytokinesis does not occur. D) The nucleolus disappears and then reappears. E) A cleavage ...
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... contrast to family B, in which all affected persons died before 30 years of age. In family A, the founder of the mutation was the patient I-2. The affected children III-10 and III-12 received an associated with the disease haplotype 5-2-3 from their affected mothers (II-5 and II-7). The other childr ...
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... Design siRNAs to knock down the expression of four genes that influence how cells respond upon exposure to DNA damaging agents; ATM, ATR, EXO1 and AAG Each group will design an siRNA sequence to knock down each of the four human genes listed below. i.e., every group will design siRNAs for all four s ...
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CH 8. DNA: The Universal Molecule of Life

... cells, so that the gametes finish up with only one of each pair of chromosomes. However, on some occasions the two homologous chromosomes, instead of separating, go into the same cell.  This phenomenon is known as non-disjunction. 12 BIOLOGY, CH 8 ...
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2nd 9 Weeks Study Guide! Aren`t you excited?? Chapter 10

... Mendal’s law of segregation states that during meiosis, the factos that control each trait separate, and only ______________________________ from each pair is/are passed to the offspring. The law of independent assortment states that the inheritance of alleles for one trait is not affected by the in ...
NCBI genome database - Winona State University
NCBI genome database - Winona State University

... • Value-added information is added by an expert(s) • Each record is intended to present an encapsulation of the current understanding of a gene or protein, similar to a review article • Variety of accession number prefixes (NM_ , NP_ , etc.) and status ...
< 1 ... 650 651 652 653 654 655 656 657 658 ... 1621 >

Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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