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Modeling Mutations Activity
Modeling Mutations Activity

... Activity: Modeling Gene Mutations 1. What is a mutation? _________________________________________________________________ _______________________________________________________________________________________ Part A. Transcription and Translation Consider the following strand of DNA: ...
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A Bacterial Cell-Cycle Regulatory Network Operating in Time and

... Notable features include the diverse dynamics of histidine kinases and response regulators that are, for example, variously synthesized and degraded (CtrA), localized to the membrane and delocalized to the cytoplasm (DivK), localized to the pole and delocalized in the membrane (DivJ), and transientl ...
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... Add 100 µl Buffer AL, close the lid, and mix by pulse-vortexing for 15 s. To ensure efficient lysis, it is essential that the sample, Buffer ATL, proteinase K, and Buffer AL are thoroughly mixed to yield a homogeneous solution. Note: For small numbers of cells we recommend adding carrier RNA to Buff ...
Lab_6_Part3
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... example, m some types of gene therapy, cells are collected from the patient, transformed in the laboratory, and then put back into the patient. The more cells that are transformed to produce the needed protein, the more likely that the therapy will work. The transformation efficiency is calculated t ...
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Cellular Reproduction notes

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... causing global climate change. Major changes are expected in terms of temperature and rainfall. One of the main greenhouse gases is carbon dioxide, released when fossil fuels are burned. Another is methane gas released by cattle. These gases cause pollution of the air. They are called greenhouse gas ...
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... defences and be able to grow as a vascularized metastatic colony in another organ. Several recent reports challenge the notion that rare metastatic cells pre-exist in the primary tumour by searching for a gene expression signature between metastatic and non-metastatic tumours [2]. Indeed, several ge ...
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... with limited RNA degradation at this temperature. Incubation at 37 degrees C strongly affected the levels of these mRNAs. Four hours of incubation at this temperature resulted in extensive RNA degradation, with mRNA levels falling to 1/10th those before incubation. When relative quantification was per ...
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... he discovered that the differences in gene activity among skin cells could be traced to Hox genes, a large family of genes already known to control positioning of body parts during development. In 2004, Chang started his own lab. His team devised a method to look at expression of the 39 Hox genes—wh ...
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Chromosomes and DNA Replication

... direction of the replication fork, the other able to add nucleotides only in chunks. The first strand, which replicates nucleotides one by one is called the leading strand; the other strand, which replicates in chunks, is called the lagging strand. The Leading and Lagging Strands The Leading Strand ...
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... How Are BRCA1 and BRCA2 Genes Inherited? The inheritance of these mutated BRCA1 and BRCA2 genes is by autosomal dominance. (10) That means if the normal gene (b) is altered by mutation (B), then those who inherit one or two copies of the altered gene (Bb or BB) will be affected while those who inhe ...
Chapter 17: From Gene to Protein
Chapter 17: From Gene to Protein

... phenomenon explains the fact that there are only about 45 different tRNA molecules that pair with the 61 possible codons (three codons are always stop codons). The third nucleotide of many tRNAs can pair with more than one base. Because of the redundancy of the genetic code, these wobble tRNAs still ...
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Web resources

... yeast, the eukaryotic flavor of life is of special interest. What is true of fundamental eukaryotic processes in yeast will be conserved on other eukaryotes. Therefore upon finding a function for a gene/protein in yeast, one wants to know if similar genes/proteins are present in other organisms. Con ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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