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The genomes of four tapeworm species reveal adaptations to
The genomes of four tapeworm species reveal adaptations to

... and flukes, and a further 10 were lost in tapeworms, making their complement by far the most reduced of any studied bilaterian animal25. Among the tapeworm-specific gene losses are gene families involved in neural development (mnx, pax3/7, gbx, hbn and rax). This is somewhat surprising considering t ...
Why have organelles retained genomes?
Why have organelles retained genomes?

... explanations. One of the most widely held notions is that all genes have the potential to be expressed in the nucleus but some of the resulting proteins are too hydrophobic to be imported across the double membranes surrounding plastids and mitochondria16,17. Another proposal is that idiosyncratic b ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
The Maintenance and Propagation of Plasmid Genes in Bacterial

... carbon and nitrogen source (opine) that can be utilized only by the bacterium containing the appropriate plasmid (Drummond, 1979). Similarly, in rhizobia, plasmids appear to provide not only the ability to nodulate and fix nitrogen in leguminous plants, but also the specificity to infect particular ...
The Maintenance and Propagation of Plasmid Genes in Bacterial
The Maintenance and Propagation of Plasmid Genes in Bacterial

... carbon and nitrogen source (opine) that can be utilized only by the bacterium containing the appropriate plasmid (Drummond, 1979). Similarly, in rhizobia, plasmids appear to provide not only the ability to nodulate and fix nitrogen in leguminous plants, but also the specificity to infect particular ...
Problem Set 1A Due August 31 1. A diploid somatic cell from a rat
Problem Set 1A Due August 31 1. A diploid somatic cell from a rat

... a. Chromosomes that are separating are still duplicated. b. Spindles are not coming from a common spindle pole body. c. Sister chromatids do not have identical alleles for the B gene. d. Two alleles of the D gene are on one chromosome. e. No alleles of the A gene are on the homologous chromosome. f. ...
A SSR marker linked to theB12gene that confers resistance to race
A SSR marker linked to theB12gene that confers resistance to race

... The 146 bp allele amplified by marker CIR246 is thus present in all accessions resistant to race 18 of Xam , regardless of the resistance gene or gene complex present (B 12 , B 2 B 3 , or B 9L B 10L ). The resistance of 101-102B to race 18 is attributed to a gene complex formed by the major genes B ...
Oocyte-Specific Expression of Growth/Differentiation Factor-9
Oocyte-Specific Expression of Growth/Differentiation Factor-9

... proteins, which are capable of inducing de novo cartilage and bone formation and appear to be essential for normal skeletal development during mammalian embryogenesis (13-l 8); and giiai cell-derived neurotrophic factor, which can promote the survival of midbrain dopaminergic neurons (19). The biolo ...
The Structure and Function of Large Biological Molecules
The Structure and Function of Large Biological Molecules

... •  Lipids are the one class of large biological molecules that do not form polymers •  The unifying feature of lipids is having little or no affinity for water •  Lipids are hydrophobic because they consist mostly of hydrocarbons, which form nonpolar covalent bonds •  The most biologically important ...
Pathology of Lymph Nodes
Pathology of Lymph Nodes

...  Lymphomas frozen at stages characterized by replication and accelerated growth  Diseases of defective cell cycle control  More often localized at presentation than indolent lymphomas  More often extranodal  Shorter natural history; median survival
Tiger beetles - Discover the Microbes Within!
Tiger beetles - Discover the Microbes Within!

... To look for the presence of Wolbachia we first must extract DNA from the beetle samples. (diagram to the left of text summarizes the steps) 1 - macerate the sample (originally we used the whole beetle but then switched to just the end of its abdomen) 2 - add buffer ATL and proteinase K and buffer AL ...
Stem Cells and Lineages: Mechanisms of Lung Development
Stem Cells and Lineages: Mechanisms of Lung Development

The Relationship Between DNA Replication and the
The Relationship Between DNA Replication and the

... added early enough. When sporulation is induced by nutrient exhaustion, HPUra does indeed inhibit development if it is added within 2 h of the time at which growth ceases to be exponential (Leighton et al., 1975 ; Shibano et al., 1978). Unfortunately, in these experiments it is not possible to ascer ...
Tutorial - Ensembl
Tutorial - Ensembl

... An Ensembl gene may have multiple transcripts reflecting alternative splicing, in this case the EPO gene only shows one transcript in Ensembl. ...
Pathology of Lymph Nodes
Pathology of Lymph Nodes

...  Lymphomas frozen at stages characterized by replication and accelerated growth  Diseases of defective cell cycle control  More often localized at presentation than indolent lymphomas  More often extranodal  Shorter natural history; median survival
Chromosomal DNA fingerprinting
Chromosomal DNA fingerprinting

... genome DNA-even a single nucleotide-base mutation-this can delete a site or create a new recognition site and result in the generation of a restriction fragment-length polymorphism (RFLP). Sequence changes may also arise as a result of insertions, deletions or inversions of DNA between sites. RFLPs ...
Beyond the ABCs: ternary complex formation in the control of
Beyond the ABCs: ternary complex formation in the control of

... cDNA expression library (Fig. 4). This approach was initially carried out to look for interactions between the B-function proteins and the candidate Antirrhinum A-function factor SQUAMOSA. When all three proteins were expressed it became clear that, although SQUA could not detectably interact with e ...
Cloning and characterization of a gene coding for a hydrophobin Fv
Cloning and characterization of a gene coding for a hydrophobin Fv

... Some mushrooms contain unique metabolites with antitumor or immunomodulating activity and have been used as medicine. Moreover, basidiomycetes have an ability to degrade lignin and cellulose in wood and have been examined for utilization in biomass conversion (Kues and Liu 2000). At present, only li ...
Temperature-sensitive control of protein activity by conditionally
Temperature-sensitive control of protein activity by conditionally

... of their products. The use of temperature-sensitive alleles is a wellestablished method that is applicable to any organism upon which temperature changes can be imposed. These include viruses, prokaryotes, yeasts, insects, plants and even amphibia and fish1. However, identifying and recovering tempe ...
Plastid endosymbiosis, genome evolution and the origin of green
Plastid endosymbiosis, genome evolution and the origin of green

... genes were lost from the plastid. The presence of short, plastid-derived sequences would be hard to detect, particularly with ancient transfers that do not retain a clear cyanobacterial signature. Nevertheless, anecdotal cases of horizontal transfer of gene segments have been reported in eukaryotes, ...
Unit 1 Biology 3
Unit 1 Biology 3

... Looking at cells Examination of cells using various microscopes reveals much about their internal organisation. Each living cell is a small compartment with an outer boundary known as the cell membrane or plasma membrane. Inside each living cell is a fluid, known as cytosol, that consists mainly of ...
Download paper (PDF format)
Download paper (PDF format)

... as a random variable. The joint distribution over the set of all genes reflects the distribution of cell “states” and how these affect transcript levels. Our ultimate goal is to estimate and understand the structure of this distribution. Most standard methods for analyzing gene expression focus on p ...
Human pigmentation genetics: the difference is only skin deep
Human pigmentation genetics: the difference is only skin deep

Section D - Prokaryotic and Eukaryotic Chromosome Structure
Section D - Prokaryotic and Eukaryotic Chromosome Structure

... B sigma factor dramatically increases the relative affinity of the enzyme for correct promoter sites. C almost all RNA start sites consist of a purine residue, with A being more common than G. D all promoters are inhibited by negative ...
Supplemental Figure and Methods
Supplemental Figure and Methods

... anatomy (7), and mammalian phenotype ontology (8)) were ranked based on vectorspace similarity to the input text (9). For each ontology term, the term, including its description, and the input text were represented as two separate word vectors excluding common stop words, and the similarity of the w ...
1 - Humble ISD
1 - Humble ISD

... extra carbon is released as carbon dioxide. Acetyl CoA can also be produced from fatty acids. When the fatty acid chain contains an even number of carbons, no CO2 is released. How many Acetyl CoA molecules can be produced with the following fatty acids? a. 23C b. 18C ...
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Vectors in gene therapy

Gene therapy utilizes the delivery of DNA into cells, which can be accomplished by several methods, summarized below. The two major classes of methods are those that use recombinant viruses (sometimes called biological nanoparticles or viral vectors) and those that use naked DNA or DNA complexes (non-viral methods).
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