MyTaxa: an advanced taxonomic classifier for genomic and
... 16S rRNA gene also provides limited resolution at the species level, which represents a major limitation for epidemiological and micro-diversity studies (11). To overcome these limitations, whole-genome-based approaches and tools, comparable to those already available for the 16S rRNA gene, are high ...
... 16S rRNA gene also provides limited resolution at the species level, which represents a major limitation for epidemiological and micro-diversity studies (11). To overcome these limitations, whole-genome-based approaches and tools, comparable to those already available for the 16S rRNA gene, are high ...
Lack of biological significance in the `linguistic features` of
... indistinguishable graphs. We obtained essentially the same ‘negative’ result for many different natural DNAs, among others: (i) the human HSRETBLAS (cf. above), and (ii) the E.coli sequence ECUW89 (cf. above); see Figure 4b. These results demonstrate quantitatively that the Zipf analysis (2) is unab ...
... indistinguishable graphs. We obtained essentially the same ‘negative’ result for many different natural DNAs, among others: (i) the human HSRETBLAS (cf. above), and (ii) the E.coli sequence ECUW89 (cf. above); see Figure 4b. These results demonstrate quantitatively that the Zipf analysis (2) is unab ...
Plant–nematode interactions
... plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode species, have been produced [42]. ...
... plant-parasitic nematodes Broad investigations of the genomes and gene products of plant-parasitic nematodes are also underway. More than 200 000 nematode ESTs from 28 nematode species, excluding C. elegans but including 19 animal- and seven plant-parasitic nematode species, have been produced [42]. ...
Identification of a novel viral protein in infectious bursal disease
... Dobos, 1986) and N1 (Havarstein et al., 1990), possess a second ORF partially overlapping the polyprotein gene (Havarstein et al., 1990) and a 17 kDa protein has been demonstrated by SDS PAGE of [a~S]methionine-labelled purified IPNV. However, no correlation of these products with ORF A-2 has so far ...
... Dobos, 1986) and N1 (Havarstein et al., 1990), possess a second ORF partially overlapping the polyprotein gene (Havarstein et al., 1990) and a 17 kDa protein has been demonstrated by SDS PAGE of [a~S]methionine-labelled purified IPNV. However, no correlation of these products with ORF A-2 has so far ...
Semester 1 Final exam - Complete with diagrams
... give the new embryo ____ of its new chromosomes ½ The egg gives ½ The sperm gives ½ For a total of 2/2 which equals 1 Your Name ...
... give the new embryo ____ of its new chromosomes ½ The egg gives ½ The sperm gives ½ For a total of 2/2 which equals 1 Your Name ...
reviews - Department of Genetics
... structures and functions that seem to be developmentally and physiologically unrelated, the interrelationships of which might only become evident once the gene defect is identified. Environmental factors that affect the expression of a trait can be mistaken as an effect of genetic modifiers. These f ...
... structures and functions that seem to be developmentally and physiologically unrelated, the interrelationships of which might only become evident once the gene defect is identified. Environmental factors that affect the expression of a trait can be mistaken as an effect of genetic modifiers. These f ...
Molecular insights into the causes of male infertility
... be involved in the regulation of male sexual differentiation and defects will be manifest as phenotypic abnormalities except where there are autosomal homologues of the gene, e.g. DAZ. There are several other Y genes in the long arm of the Y but little is known about the clinical importance of these ...
... be involved in the regulation of male sexual differentiation and defects will be manifest as phenotypic abnormalities except where there are autosomal homologues of the gene, e.g. DAZ. There are several other Y genes in the long arm of the Y but little is known about the clinical importance of these ...
Convergent evolution of complex regulatory
... intermingled enhancers are specific either for the genitals or for the digits, whereas others are used by both structures. We asked whether the large spacing between these enhancers is necessary for their proper activities—for example, to isolate them from one another and prevent undesired regulator ...
... intermingled enhancers are specific either for the genitals or for the digits, whereas others are used by both structures. We asked whether the large spacing between these enhancers is necessary for their proper activities—for example, to isolate them from one another and prevent undesired regulator ...
Glutathione S-transferase copy number variation alters lung gene expression M.W. Butler*
... as xenobiotics present in tobacco smoke, as well as other carcinogens and pesticides, and their isoforms are divided into seven classes: a (GSTA), m (GSTM), p (GSTP), h (GSTT), f (GSTZ), s (GSTS) and v (GSTO) [29–34]. Alhough cytosolic GST enzymes are a central part of the lung’s molecular detoxific ...
... as xenobiotics present in tobacco smoke, as well as other carcinogens and pesticides, and their isoforms are divided into seven classes: a (GSTA), m (GSTM), p (GSTP), h (GSTT), f (GSTZ), s (GSTS) and v (GSTO) [29–34]. Alhough cytosolic GST enzymes are a central part of the lung’s molecular detoxific ...
Supplementary Data File Supplementary Figures Figure S1
... Figure S1. Hypothetical example of variability count distributions for a pathway and a reference. A. The reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category ...
... Figure S1. Hypothetical example of variability count distributions for a pathway and a reference. A. The reference distribution corresponds to a hypothetical data set with 10,000 genes where 2,500 genes are in the low variability category, 5000 in the medium and 2500 in the high variability category ...
Bethesda Guidelines and MSI Testing
... Resistant to cytotoxic agents that acted by damaging DNA. Raised possibility that DNA MMR deficient cells might be relatively resistant to some types of cytotoxic chemotherapy. *Carethers et al. J Clin Invest 98:199-206, 1996. Ribic et al. N Engl J Med 349:247-257, 2003. ...
... Resistant to cytotoxic agents that acted by damaging DNA. Raised possibility that DNA MMR deficient cells might be relatively resistant to some types of cytotoxic chemotherapy. *Carethers et al. J Clin Invest 98:199-206, 1996. Ribic et al. N Engl J Med 349:247-257, 2003. ...
U2Word
... g. In addition to discerning the triplet characteristic, they reasoned that i. there are 4x4x4 = 64 ways to combine four bases in threes. With 64 possible codons to specify 20 AAs, there would be many AAs that had more than one codon. (Degeneracy) ii. the is no “punctuation” that demarcates each cod ...
... g. In addition to discerning the triplet characteristic, they reasoned that i. there are 4x4x4 = 64 ways to combine four bases in threes. With 64 possible codons to specify 20 AAs, there would be many AAs that had more than one codon. (Degeneracy) ii. the is no “punctuation” that demarcates each cod ...
BIO301 - National Open University of Nigeria
... mutation that occurs the most frequently is the one that is most likely to become fixed in a population. Mutations leading to the loss of function of a gene are much more common than mutations that produce a new, fully functional gene. Most loss of function mutations are selected against. But when s ...
... mutation that occurs the most frequently is the one that is most likely to become fixed in a population. Mutations leading to the loss of function of a gene are much more common than mutations that produce a new, fully functional gene. Most loss of function mutations are selected against. But when s ...
Gel Electrophoresis - Integrated DNA Technologies
... Polyacrylamide gel is the result of polymerizing acrylamide monomers into long chains and then cross-linking the chains with a bifunctional compound. A number of these bifunctional cross-linkering compounds are known including ethylene diacrylate, N,N’bisacrylycystamine (BAC), and N,N’-diallyltartar ...
... Polyacrylamide gel is the result of polymerizing acrylamide monomers into long chains and then cross-linking the chains with a bifunctional compound. A number of these bifunctional cross-linkering compounds are known including ethylene diacrylate, N,N’bisacrylycystamine (BAC), and N,N’-diallyltartar ...
Early germline development in Caenorhabditis elegans
... presence of PIE-1 may be sufficient to interfere with RNA polymerase II activity. More recently, evidence that PIE-1 can function directly as a transcriptional repressor has come from studies where PIE1’s effects on transcription were analysed in HeLa cell culture (Batchelder et al., 1999). By fusin ...
... presence of PIE-1 may be sufficient to interfere with RNA polymerase II activity. More recently, evidence that PIE-1 can function directly as a transcriptional repressor has come from studies where PIE1’s effects on transcription were analysed in HeLa cell culture (Batchelder et al., 1999). By fusin ...
Splicing together sister chromatids
... testing this possibility would require further research. Yet, additional mitotic factors are likely influenced by splicing deregulation. The results by Peters and colleagues suggest that APC2 (also known as ANAPC2), a core component of the anaphase-promoting complex (APC/C) involved in the removal o ...
... testing this possibility would require further research. Yet, additional mitotic factors are likely influenced by splicing deregulation. The results by Peters and colleagues suggest that APC2 (also known as ANAPC2), a core component of the anaphase-promoting complex (APC/C) involved in the removal o ...
e Study of RNA Polymerase Pausing by Optical Traps
... Recently, new techniques have been developed to study single RNAP molecules moving along the DNA4. These techniques have high temporal resolution and allow for the study of low probability events from single molecules which would otherwise be ...
... Recently, new techniques have been developed to study single RNAP molecules moving along the DNA4. These techniques have high temporal resolution and allow for the study of low probability events from single molecules which would otherwise be ...
Cover Letter
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
... by the glimmer and gene mark. Gap -1 is more compact than Gap 20. Thus the LORF is selected. CDS 24352 - 24798 /note=It is worth noticing that the gap is 94, bigger than the 30 limit. CDS 24795 - 25142 /note=Start at 24795 has better score and longer ORF than 24810 (called by Glimmer and GeneMark) C ...
Molecular Diagnostics in Cancer
... Naturally, patients and physicians want to know as soon as possible whether a treatment is working. Molecular diagnostics that can be repeated multiple times over the course of treatment, such as simple blood tests, have been developed for colon and several other cancers to examine treatment respons ...
... Naturally, patients and physicians want to know as soon as possible whether a treatment is working. Molecular diagnostics that can be repeated multiple times over the course of treatment, such as simple blood tests, have been developed for colon and several other cancers to examine treatment respons ...
PDF
... selectively inhibits the growth of human cancer cells [10]. Under specified conditions cancer cell growth was inhibited more than 90 percent while control cells were inhibited less than 50 percent ...
... selectively inhibits the growth of human cancer cells [10]. Under specified conditions cancer cell growth was inhibited more than 90 percent while control cells were inhibited less than 50 percent ...
PDF
... neomycin resistance gene (Neo) and the Cre recombinase gene, driven by a testes-specific promoter is shown below the map. LoxP sites are shown in blue triangles. The targeted loci before (890 + Neo) and after (890) the deletion of the testes-specific Cre-Neo cassette are shown. The probes used for ...
... neomycin resistance gene (Neo) and the Cre recombinase gene, driven by a testes-specific promoter is shown below the map. LoxP sites are shown in blue triangles. The targeted loci before (890 + Neo) and after (890) the deletion of the testes-specific Cre-Neo cassette are shown. The probes used for ...
BLSSpeller: exhaustive comparative discovery of
... (osa), Brachypodium distachyon (bdi), Sorghum bicolor (sbi) and Zea mays (zma). We adopt a gene-centric approach, where the promoter sequences of orthologous genes are grouped into gene families. A word-based discovery algorithm was designed to exhaustively report all genome-wide conserved motifs. T ...
... (osa), Brachypodium distachyon (bdi), Sorghum bicolor (sbi) and Zea mays (zma). We adopt a gene-centric approach, where the promoter sequences of orthologous genes are grouped into gene families. A word-based discovery algorithm was designed to exhaustively report all genome-wide conserved motifs. T ...
Gene tree reconstruction and orthology analysis based on
... P r[F, G | λ, µ] is called the likelihood and we will in Section 5.1 show how it can be approximated with small error. The posterior distribution thus assigns to a state (G, λ, µ) the probability that, in the gene evolution process: G was the gene tree, λ was the birth rate, and µ was the death rate ...
... P r[F, G | λ, µ] is called the likelihood and we will in Section 5.1 show how it can be approximated with small error. The posterior distribution thus assigns to a state (G, λ, µ) the probability that, in the gene evolution process: G was the gene tree, λ was the birth rate, and µ was the death rate ...