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mobile genetic elements and cancer. from mutations to gene therapy
mobile genetic elements and cancer. from mutations to gene therapy

... and divides MEs into two groups: transposons that relocate via the “cut and paste” mechanism, and retroelements that make use of RNA intermediates and reverse transcription. The grouping within these classes is also universal to diverse organisms, with retroelements classified into two groups (LTR-, ...
Name Date Block__ Biology • So far in the course we have
Name Date Block__ Biology • So far in the course we have

... (A) always pairs with (T) A-T. Guanine (G) always pairs with Cytosine (C) G-C. This base pairing is called complementary. ...
3.1 Genetics
3.1 Genetics

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DNA and the Genome
DNA and the Genome

... A further type of RNA is found in the cell’s cytoplasm. This is called tRNA (transfer RNA) and is made of a single chain of nucleotides. It is folded into a 3D structure, held together by hydrogen bonds. ...
Genetic Technology
Genetic Technology

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Science – Part 1 For each of the questions or incomplete statements
Science – Part 1 For each of the questions or incomplete statements

... dominant over the gene for black fur (g). If 50% of a large litter of squirrels are gray, the parental cross that produced this litter was most likely A. B. C. D. ...
chromosome 17
chromosome 17

... • Increases or decreases in size do not correlate with number of genes • Polyploidy in plants does not by itself explain differences in genome size • A greater amount of DNA is explained by the presence of introns and nonprotein-coding sequences than gene duplicates ...
Unit 5: Gene Expression and Mutation Genetics 2013
Unit 5: Gene Expression and Mutation Genetics 2013

... - _______________________ part secretes polypeptide hormones directly into the bloodstream  ___________________________________________________________________________ produces either endocrine or exocrine cells  If transcription factor pdx-1 is activated, some ____________________________________ ...
Bio Study Guide So I don`t Fail SECTION 1 DEFS Element
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Chapter Four
Chapter Four

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DNA/RNA/Protein Synthesis Replication Cell Division
DNA/RNA/Protein Synthesis Replication Cell Division

... Griffith “F” for failing to find genetic material! But… He found TRANSFORMATION Griffith injected mice with heat killed disease causing bacteria and alive good bacteria. The mice died of pneumonia. Some “factor” caused good bacteria to become disease causing bacteria. This is called TRANSFORMATION! ...
Yeast Expression Vector (example) (baker’s yeast) LEU2 μ =  2 micron plasmid
Yeast Expression Vector (example) (baker’s yeast) LEU2 μ = 2 micron plasmid

... (Even though the hexagon looks like a protein here) U. Arizona ...
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Meaning and Molecular Data - Circle

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By Michael Harwood This article was catalysed
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... made of exactly the same chain of amino acids! Astounding. We had never imagined this possibility — although it clearly happens in baking: Take the same ingredients and you’ll get different cakes if you bake them fast or slow. There seems to be an extra layer of information based on which of the red ...
The human genome
The human genome

... • SNPs are DNA sequence variations that occur when a single nucleotide (A,T,C,or G) in the genome sequence is altered. • For a variation to be considered a SNP, it must occur in at least 1% of the population. • SNPs, which make up about 90% of all human genetic variation, occur every 100 to 300 base ...
The molecular natural history of the human genome
The molecular natural history of the human genome

... radically over the next few years, perhaps to the point that the reading of a megabase of DNA can be performed on a time scale not much greater than the reading of a megabyte of data by current computers. Whole genome sequences will then be available for numerous members of our population and for ma ...
Genetics Session 5b_2016
Genetics Session 5b_2016

... so individuals at the genetic tails will tend to be 20cm apart. That’s about the same as we get from knowing the parents. However, the point is not to predict so much as to classify. Personalized medicine is about targeting therapy: who is most likely to need the drug; or perhaps more importantly, w ...
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Mechanisms of Evolution (on

... • Genetic drift refers to the change in a type of genes in a population due to a random occurrence. In other words, a random circumstance causes a certain genetic trait to become more common or rarer over time. Occurrences of Genetic Drift: • Genetic drift can be seen in these examples: • An explodi ...
Name - LEMA
Name - LEMA

... Using dye-labeled nucleotides, scientists can stop replication at any point along a single DNA strand. The fragments can then be separated by size using gel electrophoresis and “read,” base-by-base. The Human Genome Project was a 13-year international effort to sequence all 3 billion base pairs in h ...
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Gene duplication and divergence

... changed through time. As we noted, early vertebrates had a single globin gene. More recent descendants of these organisms have more than one globin gene, but these are clearly derived from the original gene, as we can see from the sequence. The figure above shows at what stage in the history of life ...
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... human body. The enzymes have evolved to function best at this temperature. 7) What is a restriction digest and what does it have to do with gel electrophoresis? A restriction digest is a chemical reaction where restriction enzymes cut up a strand of DNA into smaller pieces based on the number and lo ...
8.2 Structure of DNA TEKS 3F, 6A, 6B
8.2 Structure of DNA TEKS 3F, 6A, 6B

... • In the early 1950’s a British scientist named Rosalind Franklin began to study DNA. • Rosalind wanted to see what she was studying, so she took pictures of DNA with an X-ray. • Franklin’s x-ray images suggested that DNA was a double helix. • She does not receive much of the credit that she deserve ...
Overview of Articles for the literature talks Nr PMID Titel Date
Overview of Articles for the literature talks Nr PMID Titel Date

... The vast non-coding portion of the human genome is full of functional elements and diseasecausing regulatory variants. The principles defining the relationships between these elements and distal target genes remain unknown. Promoters and distal elements can engage in looping interactions that have b ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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