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lecture notes
lecture notes

... write: mutS mutH mutL- all required for mismatch repair Genetic evidence that work together- all show similar spectrum, including hotspots- Fig 16 idea that some sites in DNA are more prone to replication mismatch errors than others and these are normally repaired by MM repair- even though not clear ...
Introduction to DNA Microarrays
Introduction to DNA Microarrays

... Since DNA carries a negative charge, applying a positive charge on a pad “corrals” DNA onto that spot – This is used to build custom arrays by washing the chip in a single stranded DNA solution, biasing the desired spot on the chip, and then chemically fixing the DNA to that spot ...
Chapter 2
Chapter 2

... transcriptions stops ...
XOR - SNU Biointelligence Lab!!
XOR - SNU Biointelligence Lab!!

... 3X3 chessboard: 10 bit strings (one for backup, the other nine for the nine squares of the board) ...
Practice Problems for final exam:
Practice Problems for final exam:

... 13. In four-o‚clock flowers, red flower color, R, is incompletely dominant over white, r. This results in the heterozygous plants being pink-flowered. If you wanted to produce four o‚clock seed, all of which would yield pink-flowered plants when sown, how would you do it? 14. Thalassemia is a type o ...
Will Entrez Find Every Sequence Record?
Will Entrez Find Every Sequence Record?

... This is the search that was completed using fields (orgn, gene) and filters ...
DNA
DNA

... Unit 3 Genetics – Unit 12 Molecular Genetics: (12.2) Replication of DNA-class key ...
Huntington`s disease: Understanding a mutation - LENS
Huntington`s disease: Understanding a mutation - LENS

... Describe a situation where the effect of environment on phenotype can be observed and potentially  reversed if the environment changes.  ...
GENETICS: BIOLOGY HSA REVIEW
GENETICS: BIOLOGY HSA REVIEW

... must be copied because DNA cannot leave the nucleus. Instead of sending out DNA, copies of genes are sent into the cell to direct the assembly of proteins. These working copies are messenger-RNA molecules made from a DNA template. Transcription requires the help of enzymes. RNA polymerase, unwinds t ...
7 DNAGeneEx
7 DNAGeneEx

... 9 The approximate number of nucleotides found in an mRNA molecules that codes for a protein that is 15 amino acids long. (Spell out the answer). 10 The unique nitrogenous base found in DNA but not RNA. 11 The type of protein mutation in which only a single amino acid has changed from the original pr ...
AP Biology
AP Biology

... ii. Compare the actual number of amino acids to your prediction. Were they the same? If not, what could account for the difference? To earn credit for AP Lab 3, you will need to submit the following items ...
The Hershey-Chase Blender Experiment
The Hershey-Chase Blender Experiment

... • infect these radioactive bacteria with phages • progeny phages will be radioactive • phages radioactive with S-35 will have all the radioactivity confined to proteins, since sulfur occurs in two amino acids (cysteine and methionine) but not in DNA • phages radioactive with P-32 will have all the r ...
C - My CCSD
C - My CCSD

... • When cells reproduce, then need to be able to pass the “cell template” to the new cell they are creating • In order to accomplish this, they need to make an entirely new copy of the genes within the nucleus. – DNA Replication: the process by which DNA in a cell is copied before it undergoes cell d ...
CONNECTION: Many viruses cause disease in animals and plants
CONNECTION: Many viruses cause disease in animals and plants

... – A harmless version of the smallpox virus containing genes from other infectious agents ...
4. - UKZN Management Information
4. - UKZN Management Information

... Assume , in humans, that the difference in skin colour is due primarily to two pairs of genes which segregate independently: BBCC is black, bbcc is white, any three of the genes in black produce dark skin, any two medium skin, and anyone produces light skin colour. Give the genotypes of parents who ...
DNA Sample Collection from Animal Companions General Shipping
DNA Sample Collection from Animal Companions General Shipping

... General Shipping Instructions – Overnight shipping is not required. However, to make sure that your precious sample arrives safely we strongly suggest using a shipping method with tracking or delivery confirmation. U.S. Priority Mail with delivery confirmation is inexpensive and reliable. Cheek Swab ...
How does a cell control all of its activities?
How does a cell control all of its activities?

... Enzymes Lock and Key Theory: Enzymes control chemical reactions: (2 types of chemical reactions) 2.) Using enzymes to build molecules: Substrates connects to enzyme at active site Creates enzyme substrate complex Enzyme bring substrates together to help make bonds ...
ACAF/00/25 - Advisory Committee on Animal Feedingstuffs (ACAF)
ACAF/00/25 - Advisory Committee on Animal Feedingstuffs (ACAF)

... which appeared to be less than 400 bp in length, suggesting that it did not contain DNA fragments of sufficient length to contain a potentially functional gene. Although larger fragments were not detected in the sample studied, it is possible that they may be present in maize gluten feed since its m ...
Chapter 11.qxp
Chapter 11.qxp

... Records of these struggles are left in our DNA. This is particularly true for retroviruses, such as HIV, that survive and propagate by inserting their genetic material into our genomes. Human DNA is littered with copies of these short retroviral genomes, many from viruses that caused diseases millio ...
Methods of DNA Methylation Analysis
Methods of DNA Methylation Analysis

... After bisulfite modification, PCR is performed using two sets of primers designed to amplify either methylated or unmethylated alleles. •Often referred to as MSP, or methylation sensitive PCR •Highly sensitive: can detect one methylated allele in a population of > 1000 unmethylated alleles. •Samples ...
Genes 基因
Genes 基因

... 2.4 Mutations May Cause Lossof-Function or Gain-of-Function ...
Slide 1
Slide 1

... Incorrect: You don’t know for sure if both parents have two genes for being brown (BB). They could have a Brown gene and a white gene (Bb) and still have the phenotype (what they look like) of white color ...
IV-Antifreeze Gene for Plants
IV-Antifreeze Gene for Plants

... • Reduce crop loss from early or late frosts. Concerns: - Some crops may become allergenic. - The crops may cause unknown health risks. - The flavor of the crops may be compromised. - There may be unintended effects on the plants. - Labeling not required for GM foods & people wouldn’t know they cons ...
Showing the 3D shape of our chromosomes
Showing the 3D shape of our chromosomes

... a role in all sorts of vital processes, including gene activation, gene silencing, DNA replication and DNA repair. In fact, just about any genome function has a spatial component that has been implicated in its control. Dr Fraser added: “These unique images not only show us the structure of the chro ...
Chapter 12 DNA
Chapter 12 DNA

... DNA Replication • Replication – process by which DNA duplicates or “copies” itself – during replication the strand of DNA separates into two strands – While this is happening two new strands are being formed simultaneously – This occurs at the replication fork ...
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Helitron (biology)

A helitron is a transposon found in eukaryotes that is thought to replicate by a so-called ""rolling-circle"" mechanism. This category of transposons was discovered by Vladimir Kapitonov and Jerzy Jurka in 2001. The rolling-circle process begins with a break being made at the terminus of a single strand of the helitron DNA. Transposase then sits at this break and at another break where the helitron targets as a migration site. The strand is then displaced from its original location at the site of the break and attached to the target break, forming a circlular heteroduplex. This heteroduplex is then resolved into a flat piece of DNA via replication. During the rolling-circle process, DNA can be replicated beyond the initial helitron sequence, resulting in the flanking regions of DNA being ""captured"" by the helitron as it moves to a new location.
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