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microbiology-13-14 - Trinity College Dublin
microbiology-13-14 - Trinity College Dublin

... Cell Cycle (S. Martin): This course discusses issues relating to how cell division is regulated by forces external to a cell (growth factors, contact with neighbouring cells) as well as by internal forces (the tumor suppressor proteins Retinoblastoma protein and p53) and how cancer develops as a res ...
Archea and Bacteria- The PROKARYOTES `
Archea and Bacteria- The PROKARYOTES `

Nature Rev.Genet. 8
Nature Rev.Genet. 8

... Aged mice have lower H4K12 acetylation ...
Mutations and Their Significance
Mutations and Their Significance

... • mRNA is transcribed in the nucleus, then enters the cytoplasm and attaches to a ribosome • Translation begins at AUG, the start codon. Each tRNA has an anticodon whose bases are complimentary to a codon on the mRNA strand • The ribosome positions the start codon to attract an anticodon, which is t ...
Lecture 7
Lecture 7

... Cleave the large protein using i.e trypsin, separate fragments and sequence all of them. (We do not know the order of the fragments!!) Cleave with a different reagent i.e. Cyanogen Bromide, separate the fragments and sequence all of them. Align the fragments with overlapping sequence to get the over ...
Genetic Mutations - Velma Jackson High
Genetic Mutations - Velma Jackson High

... noises. As the disease progresses, children with Tay-Sachs disease experience seizures, vision and hearing loss, intellectual disability, and paralysis. An eye abnormality called a cherry-red spot, which can be identified with an eye examination, is characteristic of this disorder. Children with thi ...
Passing it on Notes
Passing it on Notes

... possible. The dog can hear, so the owner knows his genotype is either DD or Dd. If the dog’s genotype is Dd, the owner does not wish to use him for breeding so that the deafness gene will not be passed on. This can be tested by breeding the dog to a deaf female (dd). a) Draw the Punnett squares to i ...
An excitingly predictable `omic future - Development
An excitingly predictable `omic future - Development

... genetics, cancer genetics, microbiology and virology made much bigger strides using the same technology. This may be explained by the fact that the technology was primarily designed to sequence genomes and is understandably valuable in fields in which there is great genetic variation within sample p ...
Terms to know: Biology, Hypothesis, Variable, Control, Metabolism
Terms to know: Biology, Hypothesis, Variable, Control, Metabolism

... 8. Know the four macromolecules: carbs, lipids, proteins, and nucleic acids a) the elements that make up each type of macromolecule ) b) the monomer and some common polymers for each macromolecule c) the function of each type of macromolecule d) examples each type of macromolecules 9. Why is water a ...
Control of Gene Expression
Control of Gene Expression

... • In most cases, terminally differentiated cells cannot dedifferentiate of change their cell type. • It was once thought this was due to a loss of genes. • We now know that the difference between cell types is which genes are active and which genes aren’t. • We know this because it is possible to ta ...
File
File

... formation of a single protein or enzyme • There are many genes along the DNA strand. • Each gene stores a message (genetic code) which determines how an enzyme or protein should be made in the cell • Each protein or enzyme contributes to the development of a certain characteristics in our bodies ...
The Secret Code of Life: - Richmond School District
The Secret Code of Life: - Richmond School District

... the 4 nucleotides, A,C,G and T. Only 3 nucleotides form a triplet which, when in a gene, codes for a part of a protein. There are 34 total different triplets that can be created but only 20 different amino acids. (Would a doublet code work just as well?? i.e. only 2 nucleotides to represent 20 amino ...
Plasmid modeling Use beads to demonstrate how a gene is
Plasmid modeling Use beads to demonstrate how a gene is

... to the insulin produced in a human pancreas. How is this possible? ...
S1 Genetics and reproduction Folder sheets
S1 Genetics and reproduction Folder sheets

... 1. In the beginning (of the planet earth) how did cells multiply? 2. What is at the centre of the cell? 3. What are contained within the nucleus? 4. What are carried on these chromosomes? 5. How many chromosomes contain all of the genes needed to build a human being? 6. Name two things that are dete ...
Genetic Disorders
Genetic Disorders

... Huntington’s Disease  Huntington's disease (HD) is an inherited, degenerative brain disorder which results in an eventual loss of both mental and physical control. The disease is also known as Huntington's chorea. Chorea means "dance-like movements" and refers to the uncontrolled motions often ass ...
Variations on a Theme
Variations on a Theme

... Humans have 46 chromosomes or 23 pairs of chromosomes ...
Study Guide for Test
Study Guide for Test

... Be able to complete Central Dogma problems (e.g., manipulate the 3rd codon by creating a substitution mutation of ___ and expressing the amino acid sequence).  Know how the product of gene expression (DNA  RNA  amino acids/protein) helps in creating phenotypes.  Be able to identify types of muta ...
View PDF - Bright Star Schools
View PDF - Bright Star Schools

Honors Biology Mid
Honors Biology Mid

... 9. Explain the basic steps of cellular respiration. Know where each occurs. 10. Contrast aerobic and anaerobic processes. Explain why fermentation is necessary in some cells. 11. Relate the folded membranes of cellular structures to the production of ATP. 12. Differentiate between the various proces ...
Honors Biology
Honors Biology

... 9. Explain the basic steps of cellular respiration. Know where each occurs. 10. Contrast aerobic and anaerobic processes. Explain why fermentation is necessary in some cells. 11. Relate the folded membranes of cellular structures to the production of ATP. 12. Differentiate between the various proces ...
03i 2015 0302 Delta X and dx I
03i 2015 0302 Delta X and dx I

BIOCHEMISTRY IN PERSPECTIVE Organelles and Human Disease
BIOCHEMISTRY IN PERSPECTIVE Organelles and Human Disease

... proteins coded for by mutated genes and ER stress cause a vast number of diseases. Cystic fibrosis (CF) is a prominent example of a disease caused by misfolded proteins. CF is an ultimately fatal inherited disorder in which the lack of a specific type of plasma membrane chloride channel, the cystic ...
MCD – Immunology 6 - T-lymphocytes and antigen recognition Anil
MCD – Immunology 6 - T-lymphocytes and antigen recognition Anil

... Histocompatibility Complex. These present antigens to T-cells and come in 2 classes: MHC Class I – these are presented on nearly all cells. MHC Class II – these are only presented on special APCs (antigen presenting cells such as B-lymphocytes, macrophages and dendritic cells. ...
Extracellular matrix
Extracellular matrix

... • Collagens: Triple helical rod and non-collagenous domains. Important structural role. Extensive post-translational modifications • Fibronectin: adhesive glycoprotein in matrix and plasma • Proteoglycans: GAG-chains attached to core protein. • Laminins: major components of basement membranes • Matr ...
comp - Imtech - Institute of Microbial Technology
comp - Imtech - Institute of Microbial Technology

... Orthologs: (proteins that share a common ancestry & function) – A pair of proteins in two organisms that align along most of their lengths with a highly significant alignment score. – These proteins perform the core biological functions shared by the two organisms. – Two matched sequences (X in A, Y ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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