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Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access
Characterisation of marsupial PHLDA2 reveals eutherian specific acquisition of imprinting Open Access

... imprinted [11,17,26-33]. These are IGF2, IGF2R, PEG1/ MEST, PEG10, INS and H19, and are from 4 independent domains. We have previously reported that there is no evidence of genomic imprinting of CDKN1C (also known as p57KIP2) in a marsupial, the tammar wallaby (Macropus eugenii) [28,34]. CDKN1C is l ...
Detection of mutation status of IgVH genes and minimal residual
Detection of mutation status of IgVH genes and minimal residual

... and unmutated IgVH status indicates that these factors may determine the course of the disease. The fact that overall survival was inferior for the subgroups with unmutated IgVH, 11q-, or 17p-, suggests that response to therapy may be different in genetic subgroups[19-21]. In particular, the deletio ...
A-level Biology Previous essay titles and mark schemes
A-level Biology Previous essay titles and mark schemes

... 3. Succession, biodiversity, species and individuals in a community 4. Human impacts on the environment and its effect on relationships between organisms – including farming 4. Gene technology and GMO and ...
Functional Diversiication within the Family of B
Functional Diversiication within the Family of B

... abscission. GNC and GNL belong to the 11-member family of B-class GATA transcription factors that are characterized to date solely by their high sequence conservation within the GATA DNA-binding domain. The degree of functional conservation among the various B-class GATA family members is not unders ...
Keratins and skin disorders
Keratins and skin disorders

... The link between keratin intermediate filament proteins and inherited skin fragility disorders was first discovered in the early 1990s [1–3] and proved a turning point in our understanding of intermediate filament function. The growing number of keratin mutations published over the last 10 years as ...
Complex Lipids from Pathogenic Microorganisms
Complex Lipids from Pathogenic Microorganisms

... supplementation completely reversed the viability and differentiation defects of both mutants (4). Thus, Leishmania has undergone two major metabolic shifts: first in de-emphasizing the metabolic roles of SLs themselves in growth, signaling, and maintenance of membrane microdomains, which may arise ...
Regulation of Bacterial Conjugation in Microaerobiosis by
Regulation of Bacterial Conjugation in Microaerobiosis by

... would identify activators, and mutations that increased tra expression would identify repressors. The trials were expected to reveal mutations that altered tra operon expression in aerobiosis and also in microaerobiosis, because the centers of Salmonella colonies become microaerobic during growth (A ...
inactivation of the odontogenic ameloblast
inactivation of the odontogenic ameloblast

... changes seen during human periodontal disease and suggest that ODAM plays a role in maintaining periodontal integrity. Materials and Methods All experimental protocols and animal handling were approved by the Comité de déontologie de l’expérimentation sur les animaux of Université de Montréal. Gener ...
The Meaning of Sex: Genes and Gender Lecture Three—Sex and
The Meaning of Sex: Genes and Gender Lecture Three—Sex and

... hermaphrodite X chromosomes and repress transcription. I'd like to show you now some images of what it looks like when the X chromosomes are bound to dosage compensation protein, to dosagecompensated X chromosomes. In this case, we have an embryo, and this embryo has been stained with a dye that in ...
Deep Insight Section Genomic Imprinting: Parental differentiation of the genome
Deep Insight Section Genomic Imprinting: Parental differentiation of the genome

... Figure 11: 15mat imprinted domain: Physical examination of the imprinted domain on maternally inherited chromosome 15 reveals DNA cytosine methylation, histone H3 tail methylation at lysine 9, recruitment of histone deacetylating enzymes, and deacetylated histones. These features are typical of clos ...
Lesson 6- Macromolecules
Lesson 6- Macromolecules

... structures are different, but their chemical formulas are the same Copyright Cmassengale ...
Introduction: - Statistical Science
Introduction: - Statistical Science

... outcome related datasets. The target phenotype is shown in red. The overlap of the top 100 gene markers in the Ann Arbor ‘responders’ and the top 100 genes in each dataset distinction was quantified using a hypergeometric distribution and the p-value is reported in the last column. About half of the ...
Meiosis and Sexual Reproduction
Meiosis and Sexual Reproduction

... Same genes don’t mean same genes exactly!!! ...
1200 Paul Winter
1200 Paul Winter

... during protein synthesis  STOP codons: TGA, TAA and TAG  A nonsense mutation is a base change that creates a new STOP codon C>T: CGA>TGA: Arginine>STOP C>A: TCA>TAA: Serine >STOP ...
File
File

... b. If one stop codon, such as UGA, is found to have a different effect on translation than another stop codon, such as UAA. c. If prokaryotic organisms are able to translate a eukaryotic mRNA and produce the same polypeptide. d. If several codons are found to translate to the same amino acid, such a ...
Studies on the Mechanisms of Homolog Pairing and Sister
Studies on the Mechanisms of Homolog Pairing and Sister

... subunit SCC3 binds to the ring through its interaction with SCC1 (Gruber et al., 2003; Schleiffer et al., 2003). Ring-like cohesin is thought to hold sister chromatids together by surrounding and entrapping them, but direct proof is absent. There are several models to explain how cohesin embraces th ...
The roles of the Drosophila JAK/STAT pathway
The roles of the Drosophila JAK/STAT pathway

... addition to roles during larval hematopoiesis reminiscent of the requirement for this pathway in mammalian systems, the JAK/STAT pathway in Drosophila is also involved in a number of other developmental events. Recent data has demonstrated further roles for the JAK/STAT pathway in the establishment ...
DYAD in meiotic chromosome organisation - Development
DYAD in meiotic chromosome organisation - Development

... probes which were labelled with 32P. In situ hybridisation was carried out as described earlier (Siddiqi et al., 2000) using antisense riboprobe synthesised from the complete coding region of the DYAD cDNA. Control experiments using sense RNA gave no signal (data not shown). ...
ADVANTAGES OF FETAL CELLS IN NON
ADVANTAGES OF FETAL CELLS IN NON

Notification of a Notifiable Low Risk Dealing
Notification of a Notifiable Low Risk Dealing

... (A) the plant is male sterile and is unable to set seed; or (B) if the plant is male sterile and can set seed —all vents and drains in the facility are screened with mesh or filters that block the escape of viable pollen and seed; or (C) before flowering, all inflorescences are wholly enclosed in ba ...
Abstract
Abstract

... knowledge, only 4 kb of the promoter region have been studied so far. Interestingly, as shown in the study of Monani et al.1, SMN1 promoter has a 2-fold higher activity compared to SMN2, albeit strikingly similar nucleotide sequence. An alternative hypothesis is that differences in the transcription ...
How Biologists Conceptualize Genes: An empirical study
How Biologists Conceptualize Genes: An empirical study

... Quite unlike Gene-P, Gene-D is defined by its molecular sequence. A Gene-D is a developmental resource (…) which in itself is indeterminate with respect to phenotype (…). To be a gene for N-CAM, the so-called "neural cell adhesion molecule," for example, is to contain the specific nucleic acid seque ...
Towards identifying the full set of genes involved in post
Towards identifying the full set of genes involved in post

... ascorbate and a guiacol peroxidase which ...
Pet_SUMO manual
Pet_SUMO manual

... protein (Saitoh et al., 1997). Smt3, hereby referred to as SUMO, is a member of a ubiquitin-like protein family that regulates several cellular processes including apoptosis, nuclear transport, and cell cycle progression (Muller et al., 2001). Like ubiquitin, SUMO covalently attaches to lysine side ...
The trp Operon - aandersonbiology
The trp Operon - aandersonbiology

... operon. Jacob and Monod devised this model in 1961 to explain how a particular set of genes are expressed in prokaryotes. Although operons are not present in eukaryotes, the expression of genes in eukaryotes works in a similar fashion. Eukaryotic gene expression is controlled at multiple levels. Gen ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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