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... 4) PAP adds As slowly, CFI, CFII and CPSF fall off 5) PABII binds, add As rapidly until 250 ...
... 4) PAP adds As slowly, CFI, CFII and CPSF fall off 5) PABII binds, add As rapidly until 250 ...
122602 Hydrophobic Surfactant Proteins in Lung Function
... therapy. Accumulation of extracellular proteins, atypical macrophages, epithelial-cell dysplasia, and pulmonary fibrosis have been associated with mutations in SFTPB (Fig. 3). It is unclear whether these pathological findings are caused by chronic abnormalities in surface tension and resultant atele ...
... therapy. Accumulation of extracellular proteins, atypical macrophages, epithelial-cell dysplasia, and pulmonary fibrosis have been associated with mutations in SFTPB (Fig. 3). It is unclear whether these pathological findings are caused by chronic abnormalities in surface tension and resultant atele ...
Huntington`s Disease Like-2: Review and Update
... most recently identified family member, JPH4, is also expressed in brain. The members of this protein family each have eight repeated N-terminal units of 14 amino acids termed MORN (membrane orientation and recognition nexus) motifs which serve to anchor the protein to the plasma membrane, and a C-t ...
... most recently identified family member, JPH4, is also expressed in brain. The members of this protein family each have eight repeated N-terminal units of 14 amino acids termed MORN (membrane orientation and recognition nexus) motifs which serve to anchor the protein to the plasma membrane, and a C-t ...
NQO1 Pro187Ser polymorphism confers to the susceptibility of
... Cancer is a major public health problem worldwide and one of the leading causes of death [1]. The newly diagnosed and death for prostate cancer (PCa) were 217,730 and 32,050 respectively in USA [2]. However, PCa is a complex process and its exact mechanism has not yet been fully elucidated. Genetic ...
... Cancer is a major public health problem worldwide and one of the leading causes of death [1]. The newly diagnosed and death for prostate cancer (PCa) were 217,730 and 32,050 respectively in USA [2]. However, PCa is a complex process and its exact mechanism has not yet been fully elucidated. Genetic ...
Parental Legacy Determines Methylation and Expression of an
... kb is detected (data not shown), suggesting that transcription initiation starts within the immunoglobulin-derived DNA segment. But transcription at a cryptic promoter in the first intron of c-myc might be indistinguishable from transcript initiation within the immunoglobulin gene switch region. Thu ...
... kb is detected (data not shown), suggesting that transcription initiation starts within the immunoglobulin-derived DNA segment. But transcription at a cryptic promoter in the first intron of c-myc might be indistinguishable from transcript initiation within the immunoglobulin gene switch region. Thu ...
Highly Recurrent RET Mutations and Novel Mutations in
... previously described mutations (Fig. 1). The new mutations consisted of two point deletions, two small deletions, and six nucleotide substitutions [5⬘UT ⫺37G⬎C, c360 C⬎T (T120T), c434 T⬎G (V145G), c2081 G⬎A (R694Q), c2862 G⬎A (G954G), and c2881 T⬎C (F961L)]. Seven of 12 (58%) of the RET mutations we ...
... previously described mutations (Fig. 1). The new mutations consisted of two point deletions, two small deletions, and six nucleotide substitutions [5⬘UT ⫺37G⬎C, c360 C⬎T (T120T), c434 T⬎G (V145G), c2081 G⬎A (R694Q), c2862 G⬎A (G954G), and c2881 T⬎C (F961L)]. Seven of 12 (58%) of the RET mutations we ...
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... to probe an ordered grid of yeast artificial chromosome (YAC) clones representing most of the C. elegans genome. The rab-3 probe hybridized to a single YAC clone, Y53D2, physically mapped to chromosome II (Coulson et al., 1988). Cosmids C02C12 and F11G1 were shown to contain rab-3 by Southern analys ...
... to probe an ordered grid of yeast artificial chromosome (YAC) clones representing most of the C. elegans genome. The rab-3 probe hybridized to a single YAC clone, Y53D2, physically mapped to chromosome II (Coulson et al., 1988). Cosmids C02C12 and F11G1 were shown to contain rab-3 by Southern analys ...
Joint analysis of the influence of CYP11B1 and DGAT1 genetic
... calculating regression coefficients for each gene separately. However, in a joint analysis, uniting both alleles in 1 model, results changed for CYP11B1V, whereas DGAT1K remained highly significant (P < 0.01) for all 5 production traits. The CYP11B1V effects on milk yield (P < 0.01), fat content (P ...
... calculating regression coefficients for each gene separately. However, in a joint analysis, uniting both alleles in 1 model, results changed for CYP11B1V, whereas DGAT1K remained highly significant (P < 0.01) for all 5 production traits. The CYP11B1V effects on milk yield (P < 0.01), fat content (P ...
6.1 Chromosomes and Meiosis
... • Meiosis differs from mitosis in significant ways. – Meiosis has two cell divisions while mitosis has one. – In mitosis, homologous chromosomes never pair up. – Meiosis results in haploid cells; mitosis results in diploid cells. ...
... • Meiosis differs from mitosis in significant ways. – Meiosis has two cell divisions while mitosis has one. – In mitosis, homologous chromosomes never pair up. – Meiosis results in haploid cells; mitosis results in diploid cells. ...
PowerPoint-Präsentation - European Bioinformatics Institute
... UniProtKB/Swiss-prot, manually annotated UniProtKB/TrEMBL, computationally analyzed records Uniref, clustered by sequence identity UniParc, most comprehensive publicly available non-redundant protein sequence db, unannotated UniMES, protein sequence from metagenomic and environmental data ...
... UniProtKB/Swiss-prot, manually annotated UniProtKB/TrEMBL, computationally analyzed records Uniref, clustered by sequence identity UniParc, most comprehensive publicly available non-redundant protein sequence db, unannotated UniMES, protein sequence from metagenomic and environmental data ...
Both Polymorphic Variable Number of Tandem Repeats
... risk of autoimmune diabetes in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is associated with short alleles of the 5⬘-insulin VNTR (17). Therefore, we hypothesized that the AIRE protein may function as a regulator of the insulin gene through the VNTR region. In the presen ...
... risk of autoimmune diabetes in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is associated with short alleles of the 5⬘-insulin VNTR (17). Therefore, we hypothesized that the AIRE protein may function as a regulator of the insulin gene through the VNTR region. In the presen ...
doyne lecture rhodopsin and autosomal dominant retinitis
... ably, most specimens donated for such research come from deceased elderly individuals. The retinas of such patients are typically severely degenerated and only an occasional specimen will provide clues as to the patho genesis of the retinal degeneration.4-8 These reports, as well as those describin ...
... ably, most specimens donated for such research come from deceased elderly individuals. The retinas of such patients are typically severely degenerated and only an occasional specimen will provide clues as to the patho genesis of the retinal degeneration.4-8 These reports, as well as those describin ...
Unit II presentation
... quantitative spectrophotometric analysis of the rate of NADPH production from NADP • Several screening test are available ...
... quantitative spectrophotometric analysis of the rate of NADPH production from NADP • Several screening test are available ...
Confrontation of scabrous expressing and non
... characterized by oversized facets that contain either too many photoreceptors, or 2 or more normal R-cell complements enclosed by only one set of pigment cells (Fig. 2I,J; Baker et al., 1990). Other defects seen in sca− eyes are ommatidia with too few photoreceptor cells, or ommatidia with abnormal ...
... characterized by oversized facets that contain either too many photoreceptors, or 2 or more normal R-cell complements enclosed by only one set of pigment cells (Fig. 2I,J; Baker et al., 1990). Other defects seen in sca− eyes are ommatidia with too few photoreceptor cells, or ommatidia with abnormal ...
Chromosomes, meiosis and traits
... • Meiosis differs from mitosis in significant ways. – Meiosis has two cell divisions while mitosis has one. – In mitosis, homologous chromosomes never pair up. – Meiosis results in haploid cells; mitosis results in diploid cells. ...
... • Meiosis differs from mitosis in significant ways. – Meiosis has two cell divisions while mitosis has one. – In mitosis, homologous chromosomes never pair up. – Meiosis results in haploid cells; mitosis results in diploid cells. ...
Supplementary Methods 1. Generation and post
... ‘basal’ level or levels that maximizes the total likelihood of all segments given that breakpoint. We then choose the optimal breakpoint by finding the breakpoint whose best model has the minimal BIC. In theory, one could continue to iterate between deconstruction and background estimation until the ...
... ‘basal’ level or levels that maximizes the total likelihood of all segments given that breakpoint. We then choose the optimal breakpoint by finding the breakpoint whose best model has the minimal BIC. In theory, one could continue to iterate between deconstruction and background estimation until the ...
The uSe of mAnnoSe SeleCTion SySTem foR gene
... seem to survive in all treatments suggesting that no significant difference in plant growth was observed when cultured either in the light or dark conditions. The results showed that light play an important role in plant photosynthesis by regulating the plant growth, metabolism and cells differentia ...
... seem to survive in all treatments suggesting that no significant difference in plant growth was observed when cultured either in the light or dark conditions. The results showed that light play an important role in plant photosynthesis by regulating the plant growth, metabolism and cells differentia ...
Engineering increased vitamin C levels in plants by overexpression
... 11, and 17; Fig. 2A). We assayed the enzymatic activity in the crude extracts of three transgenic lines (lines 3, 10, and 17), using as controls both the wild type and a line transformed with the empty vector pSOV2 (ref. 17; Table 1). We found that D-galacturonic acid reductase activity was enhanced ...
... 11, and 17; Fig. 2A). We assayed the enzymatic activity in the crude extracts of three transgenic lines (lines 3, 10, and 17), using as controls both the wild type and a line transformed with the empty vector pSOV2 (ref. 17; Table 1). We found that D-galacturonic acid reductase activity was enhanced ...
Meiosis
... In some organisms, such as the hexaploid wheat and Drosophila, the pairing of homologous chromosomes occurs prior to meiosis. However, in many other organisms such as maize, oat, humans, and mice, homologous chromosomes are not associated with each other until zygotene. Regardless of when chromosome ...
... In some organisms, such as the hexaploid wheat and Drosophila, the pairing of homologous chromosomes occurs prior to meiosis. However, in many other organisms such as maize, oat, humans, and mice, homologous chromosomes are not associated with each other until zygotene. Regardless of when chromosome ...
PDF Full-text
... keyword search (tyrosyl/tryptophanyl-tRNA synthetase; tyrosine/tryptophan–tRNA ligase) and a BLASTp search in the National Center for Biotechnology Information (NCBI) database. Next, archaea/eukarya-type TyrRS genes in the bacterial domain were collected by a BLASTp search in the NCBI database and m ...
... keyword search (tyrosyl/tryptophanyl-tRNA synthetase; tyrosine/tryptophan–tRNA ligase) and a BLASTp search in the National Center for Biotechnology Information (NCBI) database. Next, archaea/eukarya-type TyrRS genes in the bacterial domain were collected by a BLASTp search in the NCBI database and m ...
Simplified global gene expression profiling
... Chef-Ready Kit (Cat. No. A31446) for UHRR and HBRR samples. The kit enables users to generate 8 equalized Ion AmpliSeq™ libraries utilizing the robust liquid handling capabilities of the Ion Chef System. The Ion S5 XL System combined with automated library and template preparation on the Ion Chef Sy ...
... Chef-Ready Kit (Cat. No. A31446) for UHRR and HBRR samples. The kit enables users to generate 8 equalized Ion AmpliSeq™ libraries utilizing the robust liquid handling capabilities of the Ion Chef System. The Ion S5 XL System combined with automated library and template preparation on the Ion Chef Sy ...
Motif Mining from Gene Regulatory Networks
... If we are looking for n-node subgraphs, then the number of n-1 node subgraphs must be the same in real and randomized networks This is done to avoid assigning high significance to a structure only because of the fact that it includes a highly significant substructure. ...
... If we are looking for n-node subgraphs, then the number of n-1 node subgraphs must be the same in real and randomized networks This is done to avoid assigning high significance to a structure only because of the fact that it includes a highly significant substructure. ...
Chromosomal Clustering of Periodically Expressed Genes
... periodically expressed genes in stages of intraerythrocytic developmental cycle (IDC) of plasmodium falciparum. The DNA microarray data was provided by the organizers of the Critical Assessment of Microarray Data Analysis (CAMDA) 2004 competition. To this end, we first applied a multiple linear regr ...
... periodically expressed genes in stages of intraerythrocytic developmental cycle (IDC) of plasmodium falciparum. The DNA microarray data was provided by the organizers of the Critical Assessment of Microarray Data Analysis (CAMDA) 2004 competition. To this end, we first applied a multiple linear regr ...
HD13 - Columbia University
... • Account for one-third of birth defects • 40% of pediatric end-stage renal disease • 10% of adult end-stage renal disease in some countries • Etiology poorly understood because of variable expression and incomplete penetrance ...
... • Account for one-third of birth defects • 40% of pediatric end-stage renal disease • 10% of adult end-stage renal disease in some countries • Etiology poorly understood because of variable expression and incomplete penetrance ...