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Albert Szent-Györgyi Prize for Progress in Cancer Research
Albert Szent-Györgyi Prize for Progress in Cancer Research

... Cavenee is a Fellow of the National Foundation for Cancer Research and has won many honors, including the Charles S. Mott Prize of the General Motors Cancer Research Foundation. He is a member of the National Academy of Sciences, a former president of the American Association for Cancer Research, a ...
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... reduced [42]. Over expression of the nuclear phosphoprotein p53 is one of the most common abnormalities in primary human cancer and appears to be due to point mutation within a highly conserved region of the p53 gene which then encodes for a mutant, more stable protein [43]. Some experiments indicat ...
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... because typical reversion frequencies are <10-7 and a typical colony contains about 106 cells. In contrast, the mutation frequency in mutator strains is often increased about 100-fold, so within a colony of a mutator strain Lac+ (red) papilli (“microcolonies”) will appear. Assuming that you can scre ...
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... Note: A chromosome is a tightly coiled strand of DNA and within each chromosome there are many, many genes. The chromosomes within each pair are homologous. Homologous chromosomes are the same in size and function but they do have different alleles. For instance, the homologous chromosome may contai ...
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NEDD9

Neural precursor cell expressed developmentally down-regulated protein 9 (NEDD-9) is a protein that in humans is encoded by the NEDD9 gene. NEDD-9 is also known as enhancer of filamentation 1 (EF1), CRK-associated substrate-related protein (CAS-L), and Cas scaffolding protein family member 2 (CASS2). An important paralog of this gene is BCAR1.
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