UNIT 1: INTRODUCTION TO BIOLOGY
... Meiosis is a special type of cell division which creates: 1. haploid germ cells (eggs and sperm) from a diploid parent cell for sexual reproduction 2. genetic variety due to tetrad formation and crossing over O Onnee single diploid parent cell is divided to produce ffoouurr haploid daughter cells ...
... Meiosis is a special type of cell division which creates: 1. haploid germ cells (eggs and sperm) from a diploid parent cell for sexual reproduction 2. genetic variety due to tetrad formation and crossing over O Onnee single diploid parent cell is divided to produce ffoouurr haploid daughter cells ...
Prioritizing curation of mouse genes by paucity of annotations and
... has become clear that ciliopathies are an underlying cause of numerous human diseases including some types of retinitis pigmentosa and polycystic kidney disease. Once thought to be restricted to a few cell types, it is now clear that primary cilia are found on almost all vertebrate cells and are cri ...
... has become clear that ciliopathies are an underlying cause of numerous human diseases including some types of retinitis pigmentosa and polycystic kidney disease. Once thought to be restricted to a few cell types, it is now clear that primary cilia are found on almost all vertebrate cells and are cri ...
A candidate prostate cancer susceptibility gene at
... In surveying dbEST, we identified a small number of human and rabbit ESTs originating from a second, related gene. The human cDNA sequence of this related gene, encoding a predicted polypeptide of 363 residues, was also assembled from a combination of ESTs and 5´-RACE products. Radiation hybrid mapp ...
... In surveying dbEST, we identified a small number of human and rabbit ESTs originating from a second, related gene. The human cDNA sequence of this related gene, encoding a predicted polypeptide of 363 residues, was also assembled from a combination of ESTs and 5´-RACE products. Radiation hybrid mapp ...
Document
... from a single gene multiple transcripts) AS is tissue-specific (Graveley, 2001) AS is related to human diseases ...
... from a single gene multiple transcripts) AS is tissue-specific (Graveley, 2001) AS is related to human diseases ...
Preimplantation Genetic Testing
... been used extensively in major IVF clinics throughout the world since the early 1990s. Follow up studies have shown that the procedure is safe with no known adverse effects on the embryo’s potential to implant and develop normally. ...
... been used extensively in major IVF clinics throughout the world since the early 1990s. Follow up studies have shown that the procedure is safe with no known adverse effects on the embryo’s potential to implant and develop normally. ...
Primary ciliary dyskinesia: genes, candidate genes
... mutations of as many as 250 different genes coding for various ciliary proteins cause the same or similar pathologic consequences of the ciliary dysfunction. If that was true, one might expect the incidence of PCD to be much higher than actually reported (McKusick 2002). It is possible that many cil ...
... mutations of as many as 250 different genes coding for various ciliary proteins cause the same or similar pathologic consequences of the ciliary dysfunction. If that was true, one might expect the incidence of PCD to be much higher than actually reported (McKusick 2002). It is possible that many cil ...
1993 Zena Werb Zena Werb was born in Europe in 1945 and
... for physiological processes such as involution and tissue repair, and in diseases such as tumor metastasis and arthritis. Early in her studies, she found that fibroblasts secreted extracellular matrix degrading enzymes of the metalloproteinase class in inactive precursor forms. The quest for underst ...
... for physiological processes such as involution and tissue repair, and in diseases such as tumor metastasis and arthritis. Early in her studies, she found that fibroblasts secreted extracellular matrix degrading enzymes of the metalloproteinase class in inactive precursor forms. The quest for underst ...
Protocol 1 Management guidelines for unaffected
... families may still wish to consider mastectomy due to personal reasons, but the risks in these families do not warrant recommendation based on genetic risk. All cases should be discussed in the MDT. Q: When should I discuss ovarian risk? Ovarian risk should be discussed: · In women with BRCA1 or BR ...
... families may still wish to consider mastectomy due to personal reasons, but the risks in these families do not warrant recommendation based on genetic risk. All cases should be discussed in the MDT. Q: When should I discuss ovarian risk? Ovarian risk should be discussed: · In women with BRCA1 or BR ...
Chromatin: A sticky silence
... Su(var)205 encodes the HP1 protein, which is concentrated in the heterochromatin. PEV is also suppressed by extra copies of the heterochromatic Y chromosome, indicating that the global amount of heterochromatin is limited in the nucleus. A similar competition has been observed in yeast between telom ...
... Su(var)205 encodes the HP1 protein, which is concentrated in the heterochromatin. PEV is also suppressed by extra copies of the heterochromatic Y chromosome, indicating that the global amount of heterochromatin is limited in the nucleus. A similar competition has been observed in yeast between telom ...
Case 34. Sickle cell disease identified in newborn screening
... cell disease clinic or a community-based sickle cell disease organization provides access to expert medical professionals as well as other affected individuals and their families. Even if such a clinic is not available, interaction with other affected families can help the couple to learn about the ...
... cell disease clinic or a community-based sickle cell disease organization provides access to expert medical professionals as well as other affected individuals and their families. Even if such a clinic is not available, interaction with other affected families can help the couple to learn about the ...
Combination of Neuro-Fuzzy Network Models with Biological
... There are two inputs X1 and X2, and single output Y in our neuro-fuzzy network model. This model describes the intensity of relations among these 3 genes. If the inputs X1, X2 and output Y are in the same period and have similar functions, or they have regulation relationships, the error gained from ...
... There are two inputs X1 and X2, and single output Y in our neuro-fuzzy network model. This model describes the intensity of relations among these 3 genes. If the inputs X1, X2 and output Y are in the same period and have similar functions, or they have regulation relationships, the error gained from ...
Two-way clustering
... The image data of the scanned probe array is stored in a *.dat file. The Affymetrix GCOS software processes the *.dat file and generates a *.cel file, containing all numerical data of the GeneChip experiment, e.g., probe locations and PM and MM intensities. The processing involves computing a square ...
... The image data of the scanned probe array is stored in a *.dat file. The Affymetrix GCOS software processes the *.dat file and generates a *.cel file, containing all numerical data of the GeneChip experiment, e.g., probe locations and PM and MM intensities. The processing involves computing a square ...
About and Key Statistics - American Cancer Society
... For example, researchers have found that an oncogene known as SYK is overactive in retinoblastoma cells. Drugs that target the protein this gene makes are now being developed. Another gene called MDM4 also seems to be involved in the development of retinoblastoma, and drugs aimed at blocking its eff ...
... For example, researchers have found that an oncogene known as SYK is overactive in retinoblastoma cells. Drugs that target the protein this gene makes are now being developed. Another gene called MDM4 also seems to be involved in the development of retinoblastoma, and drugs aimed at blocking its eff ...
223/AP08 - EDVOTEK
... (approximately 27 kilodaltons) possesses the ability to absorb blue light and emit green light in response. This activity, known as fluorescence, does not require any additional special substrates, gene products or cofactors to produce visible light. ...
... (approximately 27 kilodaltons) possesses the ability to absorb blue light and emit green light in response. This activity, known as fluorescence, does not require any additional special substrates, gene products or cofactors to produce visible light. ...
Effective Gene Selection Method Using Bayesian Discriminant
... chromosomes using the above method. The crossover operation generates a new chromosome (offspring) out of the two parents. The mutation operation slightly perturbs the offspring. If the offspring chromosome is superior to both parents, it replaces the parent. If it is in between the two parents, it ...
... chromosomes using the above method. The crossover operation generates a new chromosome (offspring) out of the two parents. The mutation operation slightly perturbs the offspring. If the offspring chromosome is superior to both parents, it replaces the parent. If it is in between the two parents, it ...
Positive Darwinian Selection
... It is thought that sex-related genes are subject to positive selection for short periods of time during speciation as a means of erecting reproductive barriers that restrict gene flow between the speciating ...
... It is thought that sex-related genes are subject to positive selection for short periods of time during speciation as a means of erecting reproductive barriers that restrict gene flow between the speciating ...
Two ParaHox genes, SpLox and SpCdx, interact to
... characterized the detailed spatial expression pattern from pregastrula through 72 hours by whole-mount in situ hybridization, as illustrated in Fig. 1. At the mesenchyme blastula stage (Fig. 1A), SpLox transcripts are not detectable, consistent with the limited number of transcripts per embryo detec ...
... characterized the detailed spatial expression pattern from pregastrula through 72 hours by whole-mount in situ hybridization, as illustrated in Fig. 1. At the mesenchyme blastula stage (Fig. 1A), SpLox transcripts are not detectable, consistent with the limited number of transcripts per embryo detec ...
Functional tests of enhancer conservation between
... pathway for generation of GABAergic neurons is one such example. The upstream specification pathway for many GABAergic neurons in nematodes is the homeobox transcription factor UNC-30, which is orthologous to Pitx genes in mammals as well as arthropods. Not only are these genes orthologous, but, in ...
... pathway for generation of GABAergic neurons is one such example. The upstream specification pathway for many GABAergic neurons in nematodes is the homeobox transcription factor UNC-30, which is orthologous to Pitx genes in mammals as well as arthropods. Not only are these genes orthologous, but, in ...
An effect of the DGAT1 gene polymorphism on breeding
... acids share in milk what may have a negative effect on human health [Schennink et al. 2007]. In addition, it was shown that the K allele has a positive effect on intramuscular fat content of beef in Charolaise and Holstein cattle [Thaller et al. 2003a]. However, Casas et al. [2005] reported no signi ...
... acids share in milk what may have a negative effect on human health [Schennink et al. 2007]. In addition, it was shown that the K allele has a positive effect on intramuscular fat content of beef in Charolaise and Holstein cattle [Thaller et al. 2003a]. However, Casas et al. [2005] reported no signi ...
Arabidopsis Separase AESP Is Essential for Embryo Development
... AESP also contains a putative EF-hand calcium binding domain. Budding yeast Esp1 contains a calcium binding domain, which is required for its association with the spindle (Jensen et al., 2001). It is possible that the EF-hand motif in AESP plays a similar role in plants. AESP transcript levels were ...
... AESP also contains a putative EF-hand calcium binding domain. Budding yeast Esp1 contains a calcium binding domain, which is required for its association with the spindle (Jensen et al., 2001). It is possible that the EF-hand motif in AESP plays a similar role in plants. AESP transcript levels were ...
PcGs and Hox genes - Development
... elements (PREs) (Strutt et al., 1997; Orlando et al., 1998). PREs were initially identified by virtue of their ability to silence inappropriate activation of Hox reporter genes in a PcG protein-dependent fashion (Müller and Bienz, 1991; Simon et al., 1993; Chan et al., 1994). More recently, the remo ...
... elements (PREs) (Strutt et al., 1997; Orlando et al., 1998). PREs were initially identified by virtue of their ability to silence inappropriate activation of Hox reporter genes in a PcG protein-dependent fashion (Müller and Bienz, 1991; Simon et al., 1993; Chan et al., 1994). More recently, the remo ...
2 points: Genetics and DNA
... • Which subatomic particles can be found inside the nucleus of an atom? ...
... • Which subatomic particles can be found inside the nucleus of an atom? ...
Genetic control of cellularisation
... indicating that its specific role is to mediate membrane fusion at the cell plate (Lauber et al., 1997). The keule (Assaad et al., 1996) and hinkel (Strompen et al., 2002) mutants display cytokinesis defects during embryo development similar to ...
... indicating that its specific role is to mediate membrane fusion at the cell plate (Lauber et al., 1997). The keule (Assaad et al., 1996) and hinkel (Strompen et al., 2002) mutants display cytokinesis defects during embryo development similar to ...
Antioxidant and Xenobiotic-metabolizing Enzyme Gene Expression
... particularly the pH 6 optimum reducÃ-asetermed carbonyl reThe clinically useful antineoplastic agent doxorubicin is a ductase (13-16). It has been proposed that decreased enzyme multifunctional molecule, with several possible mechanisms of activity could diminish doxorubicin sensitivity (17). Carbon ...
... particularly the pH 6 optimum reducÃ-asetermed carbonyl reThe clinically useful antineoplastic agent doxorubicin is a ductase (13-16). It has been proposed that decreased enzyme multifunctional molecule, with several possible mechanisms of activity could diminish doxorubicin sensitivity (17). Carbon ...
Problem set 6 answers 1. You find a mouse with no tail. In order to
... locus (Df/+). Which of these animals will exhibit a wild-type phenotype, and of the animals that exhibit a mutant phenotype, which will exhibit the more severe phenotype (order the mutants based on strength of phenotype) when the mutation is: ...
... locus (Df/+). Which of these animals will exhibit a wild-type phenotype, and of the animals that exhibit a mutant phenotype, which will exhibit the more severe phenotype (order the mutants based on strength of phenotype) when the mutation is: ...