Conserved syntenic clusters of protein coding genes are missing in
... comparative genomics analysis to identify orthologous gene sets in humans (Homo sapiens), a lizard (green anole; Anolis carolinensis) representing a non-avian sauropsid, a galliform, (chicken; Gallus gallus) representing a basal avian order with a high quality genome assembly, and an oscine passerif ...
... comparative genomics analysis to identify orthologous gene sets in humans (Homo sapiens), a lizard (green anole; Anolis carolinensis) representing a non-avian sauropsid, a galliform, (chicken; Gallus gallus) representing a basal avian order with a high quality genome assembly, and an oscine passerif ...
Engrailed cooperates with extradenticle and homothorax to repress
... En carries out these functions, at least in part, by repressing downstream target genes (Smith and Jaynes, 1996; Tolkunova et al., 1998). It has two well-characterized repression domains, one of which binds the Groucho co-repressor complex (Han and Manley, 1993; Jaynes and O’Farrell, 1988; Jaynes an ...
... En carries out these functions, at least in part, by repressing downstream target genes (Smith and Jaynes, 1996; Tolkunova et al., 1998). It has two well-characterized repression domains, one of which binds the Groucho co-repressor complex (Han and Manley, 1993; Jaynes and O’Farrell, 1988; Jaynes an ...
Investigating the functional significance of evolutionarily conserved
... for understanding body patterning in animals. I identified and characterized the role of evolutionarily conserved protein domains of the HOX protein, Sex combs reduced (SCR), in protein function. SCR is required for establishing the identity of both the labial and prothoracic segments. To identify r ...
... for understanding body patterning in animals. I identified and characterized the role of evolutionarily conserved protein domains of the HOX protein, Sex combs reduced (SCR), in protein function. SCR is required for establishing the identity of both the labial and prothoracic segments. To identify r ...
Table 3 - HAL Descartes
... chromosomes prepared from cultured fibroblasts (patient 8) or peripheral blood cells. Metaphase chromosomes were obtained according to standard techniques. FISH was performed as previously described 62. PAC and BAC clones used in FISH experiments were provided by the BACPAC Resources Center, (CHILDR ...
... chromosomes prepared from cultured fibroblasts (patient 8) or peripheral blood cells. Metaphase chromosomes were obtained according to standard techniques. FISH was performed as previously described 62. PAC and BAC clones used in FISH experiments were provided by the BACPAC Resources Center, (CHILDR ...
Cotyledon organogenesis - Journal of Experimental Botany
... dicotyledonous synapomorphy and monocot and gymnosperm cotyledon apomorphies are represented by circles on the cladogram. The debated position of the Gnetales is also shown, according Chaw et al. ...
... dicotyledonous synapomorphy and monocot and gymnosperm cotyledon apomorphies are represented by circles on the cladogram. The debated position of the Gnetales is also shown, according Chaw et al. ...
Phylogenetic analysis of members of the genus Rickettsia using the
... Nei, 1987). The data were also examined by using parsimony and maximum-likelihood methods (, and in ). A bootstrap analysis was performed to investigate the stability of the trees obtained. Bootstrap values were obtained for a consensus tree based on 100 randomly generate ...
... Nei, 1987). The data were also examined by using parsimony and maximum-likelihood methods (, and in ). A bootstrap analysis was performed to investigate the stability of the trees obtained. Bootstrap values were obtained for a consensus tree based on 100 randomly generate ...
Plasma calcium
... parathyroid cells and the ascending loop of Henle epithelial cells to respond to changes in extracellular calcium. The parathyroid cell surface is rich in CaSR, which allows PTH secretion to be adjusted rapidly depending on the calcium concentration. Defects in the CaSR gene are responsible for vari ...
... parathyroid cells and the ascending loop of Henle epithelial cells to respond to changes in extracellular calcium. The parathyroid cell surface is rich in CaSR, which allows PTH secretion to be adjusted rapidly depending on the calcium concentration. Defects in the CaSR gene are responsible for vari ...
Dominant Suppressors of Yeast Actin Mutations That Are Reciprocally Suppressed.
... each revertant isolated was independent, cells from a single colony grown at permissive temperature (26")were used to seed each plate, and only one revertant was picked per plate. Revertants were purified by streaking for single colonies on YEPD medium at 37". During the course of the analysis, a la ...
... each revertant isolated was independent, cells from a single colony grown at permissive temperature (26")were used to seed each plate, and only one revertant was picked per plate. Revertants were purified by streaking for single colonies on YEPD medium at 37". During the course of the analysis, a la ...
SALSA MLPA probemix P222-A2 LCA mix-2 - MRC
... elements of vision and also serve as essential modulators of cellular differentiation and proliferation in diverse cell types. RDH12 belongs to a family of dual-specificity retinol dehydrogenases that metabolize both all-trans- and cis-retinols (Haeseleer et al., J Biol Chem, 2002). The RDH12 gene ( ...
... elements of vision and also serve as essential modulators of cellular differentiation and proliferation in diverse cell types. RDH12 belongs to a family of dual-specificity retinol dehydrogenases that metabolize both all-trans- and cis-retinols (Haeseleer et al., J Biol Chem, 2002). The RDH12 gene ( ...
Methods of Human Heredity Study
... Karyotype is diploid chromosome number of cell, which includes chromosome number, size, shape of individual chromosomes and other attributes (for example, position of centromere). This term was coined by Russian scientist G.A. Levitzky in 1924. In all types of higher organisms (eukaryota), the well- ...
... Karyotype is diploid chromosome number of cell, which includes chromosome number, size, shape of individual chromosomes and other attributes (for example, position of centromere). This term was coined by Russian scientist G.A. Levitzky in 1924. In all types of higher organisms (eukaryota), the well- ...
Vocabulary Definitions
... abdomen the third section of the insect body, including the digestive and reproductive organs and most of the circulatory and respiratory systems (SRB) adaptation any structure or behavior of an organism that allows it to survive in its environment (SRB, IG) aerobic cellular respiration a process by ...
... abdomen the third section of the insect body, including the digestive and reproductive organs and most of the circulatory and respiratory systems (SRB) adaptation any structure or behavior of an organism that allows it to survive in its environment (SRB, IG) aerobic cellular respiration a process by ...
HGSS2 Mendel
... has the same two alleles at a gene. For the ABO locus, those who inherit two A alleles are homozygotes as are those who inherit two B alleles or two O alleles. A heterozygote is an organism with different alleles at a locus. For example, someone who inherits an A allele from mom but a B allele from d ...
... has the same two alleles at a gene. For the ABO locus, those who inherit two A alleles are homozygotes as are those who inherit two B alleles or two O alleles. A heterozygote is an organism with different alleles at a locus. For example, someone who inherits an A allele from mom but a B allele from d ...
Genetics Questions - G. Holmes Braddock
... ____ 27. What determines the color of western white butterflies? a. genes alone. b. the environment alone c. temperature and genes d. exposure to sunlight and genes ____ 28. Which of the following supports the claim that the environment can affect genetic traits? a. Oak trees get taller as they grow ...
... ____ 27. What determines the color of western white butterflies? a. genes alone. b. the environment alone c. temperature and genes d. exposure to sunlight and genes ____ 28. Which of the following supports the claim that the environment can affect genetic traits? a. Oak trees get taller as they grow ...
Nucleotide sequence and taxonomic value of the
... saline (PBS) to give an approximate 20% (w/v) suspension. This suspension was homogenized for 2 min in a Sorvall-Omnimix homogenizer and the resulting homogenate was centrifuged in a Sorvall HB4 rotor for 10 min at lo00 r.p.m. at 4 "C. Eighteen millilitres of the middle layer was removed and centrif ...
... saline (PBS) to give an approximate 20% (w/v) suspension. This suspension was homogenized for 2 min in a Sorvall-Omnimix homogenizer and the resulting homogenate was centrifuged in a Sorvall HB4 rotor for 10 min at lo00 r.p.m. at 4 "C. Eighteen millilitres of the middle layer was removed and centrif ...
CFTR mutation classifications toward genotype
... characteristics. It is often difficult to assess the association between CFTR mutations and clinical entities that, in some cases, may have other non-CFTR related aetiologies. Other factors, such as the environment, modifier genes and the progression of the disease with age, can also affect the clin ...
... characteristics. It is often difficult to assess the association between CFTR mutations and clinical entities that, in some cases, may have other non-CFTR related aetiologies. Other factors, such as the environment, modifier genes and the progression of the disease with age, can also affect the clin ...
Hypertrophy of colonic smooth muscle: structural
... smooth muscle challenged by changes in functional demand. In the absence of such information for gastrointestinal smooth muscle, and the relevance to a clinical condition, we chose to analyze the development of megacolon associated with Hirschsprung’s disease. In this disorder constriction of the re ...
... smooth muscle challenged by changes in functional demand. In the absence of such information for gastrointestinal smooth muscle, and the relevance to a clinical condition, we chose to analyze the development of megacolon associated with Hirschsprung’s disease. In this disorder constriction of the re ...
Biophysics of Macromolecules: Problem set 4
... c) From the crystal structure with 4 binding sites, one can conclude that the binding exhibit cooperativity, but that the binding is not completely “all-or-nothing”, since the Hill coefficient is less than 4. Problem 3 Free vs. bound ligand. This problem follows essentially Problem 6.3 or 6.4, resp ...
... c) From the crystal structure with 4 binding sites, one can conclude that the binding exhibit cooperativity, but that the binding is not completely “all-or-nothing”, since the Hill coefficient is less than 4. Problem 3 Free vs. bound ligand. This problem follows essentially Problem 6.3 or 6.4, resp ...
Requirement for chitin biosynthesis in epithelial tube morphogenesis. Proc. Natl. Acad. Sci. USA 102: 17014-17019. pdf
... septate junction) and Coracle (Cor; septate junction) as indicated. Expression of epithelial polarity markers is not altered in cystic mutants. The band of staining near the top of Q is epidermis. (U–Y) Tracheal phenotype of knk and kkv mutants. Tracheal cells are labeled with GFP (green) as in A–E. ...
... septate junction) and Coracle (Cor; septate junction) as indicated. Expression of epithelial polarity markers is not altered in cystic mutants. The band of staining near the top of Q is epidermis. (U–Y) Tracheal phenotype of knk and kkv mutants. Tracheal cells are labeled with GFP (green) as in A–E. ...
Population Differences in the Polyalanine Domain and 6
... HLXB9 has 3 exons encoding a 403-amino acid protein. The HLXB9 protein functions as a transcription factor regulating gene expression in both developing and adult tissues, although little is known about target genes or protein partners. Structurally, HLXB9 contains a homeodomain, a highly conserved ...
... HLXB9 has 3 exons encoding a 403-amino acid protein. The HLXB9 protein functions as a transcription factor regulating gene expression in both developing and adult tissues, although little is known about target genes or protein partners. Structurally, HLXB9 contains a homeodomain, a highly conserved ...
Polymorphisms in Multiple Genes Contribute to the
... Mitochondrial genome instability can be quantitatively measured by the frequency of spontaneous petites in a population of yeast cells. While values can vary, the lowest petite frequencies are 1% for S. cerevisiae (Sherman 2002). This low end of the spectrum is at least 100-fold higher than the exp ...
... Mitochondrial genome instability can be quantitatively measured by the frequency of spontaneous petites in a population of yeast cells. While values can vary, the lowest petite frequencies are 1% for S. cerevisiae (Sherman 2002). This low end of the spectrum is at least 100-fold higher than the exp ...
Identification of genes that interact with glp-1, a gene
... precisely by additional mapping: two-factor mapping established the distance between unc-18 and q288 (Table 1). Threefactor mapping established the position of q288 relative to unc-18: Unc and Dpy recombinants were recovered from a strain that was unc-18 q288/vab-3 and examined for a vab-3 phenotype ...
... precisely by additional mapping: two-factor mapping established the distance between unc-18 and q288 (Table 1). Threefactor mapping established the position of q288 relative to unc-18: Unc and Dpy recombinants were recovered from a strain that was unc-18 q288/vab-3 and examined for a vab-3 phenotype ...
The molecular basis of human retinal and vitreoretinal
... Subsequently, studies suggested that haploinsufficiency is the underlying mechanism for PRPF31 mutations, i.e. the mutated allele is not expressed and the reduced gene dosage causes the disease (support for possible explanation 3) (Rio et al., 2008). Nevertheless, splicing of RPGR intron 9 has been ...
... Subsequently, studies suggested that haploinsufficiency is the underlying mechanism for PRPF31 mutations, i.e. the mutated allele is not expressed and the reduced gene dosage causes the disease (support for possible explanation 3) (Rio et al., 2008). Nevertheless, splicing of RPGR intron 9 has been ...
Plant Functional Genomics Plant Functional Genomics
... Large genomic DNA insert-containing libraries are essential for physical mapping, positional cloning, and genome sequencing of complex genomes. There are two principal large insert cloning systems that are constructed as yeast or bacterial artificial chromosomes (YACs and BACs, respectively). The YA ...
... Large genomic DNA insert-containing libraries are essential for physical mapping, positional cloning, and genome sequencing of complex genomes. There are two principal large insert cloning systems that are constructed as yeast or bacterial artificial chromosomes (YACs and BACs, respectively). The YA ...