Pair-wise sequence alignment
... • As we can start a new alignment anywhere the scores cannot be negative. • Trace-back is started at the highest values rather than at the lower right hand corner. • Trace-back is stopped as soon as a zero is encountered. ...
... • As we can start a new alignment anywhere the scores cannot be negative. • Trace-back is started at the highest values rather than at the lower right hand corner. • Trace-back is stopped as soon as a zero is encountered. ...
FOXP2: the language gene
... • The human-specific change at position 325 creates a potential target site for phosphorylation by protein kinase C together with a minor change in predicted secondary structure. ...
... • The human-specific change at position 325 creates a potential target site for phosphorylation by protein kinase C together with a minor change in predicted secondary structure. ...
The complement C3 protein family in invertebrates
... other members of the TEP family, is a GPI-linked glycoprotein originally found on endothelial cells, platelets and activated T-cells (Lin et al., 2002). CD109 suppresses transforming growth factor (TGF)-β signaling in human keratinocytes by binding to TGF-β receptor I (Finnson et al., 2006), and a h ...
... other members of the TEP family, is a GPI-linked glycoprotein originally found on endothelial cells, platelets and activated T-cells (Lin et al., 2002). CD109 suppresses transforming growth factor (TGF)-β signaling in human keratinocytes by binding to TGF-β receptor I (Finnson et al., 2006), and a h ...
32 Fungal Genetics Newsletter Ursula Kües , Michaela J. Klaus
... Often, integration occurs at multiple sites indicating that more than one plasmid copy was incorporated. This feature prompted us to study transformation with mixtures of several different plasmids in several genetic backgrounds. We found multiple cotransformation to be efficient even with four diff ...
... Often, integration occurs at multiple sites indicating that more than one plasmid copy was incorporated. This feature prompted us to study transformation with mixtures of several different plasmids in several genetic backgrounds. We found multiple cotransformation to be efficient even with four diff ...
REVIEWS
... In Drososphila embryos, snail is initially expressed in the prospective mesoderm38 (FIG. 3), where it acts as a repressor to inhibit the expression of neuroectodermal genes such as rhomboid 39 and single-minded 40. So, in Drosophila, mesoderm specification is partly carried out by the exclusion of a ...
... In Drososphila embryos, snail is initially expressed in the prospective mesoderm38 (FIG. 3), where it acts as a repressor to inhibit the expression of neuroectodermal genes such as rhomboid 39 and single-minded 40. So, in Drosophila, mesoderm specification is partly carried out by the exclusion of a ...
"Genetic Redundancy".
... normal individuals very often shared the defective genotype, homozygous for a nonsense mutation to ACTN3. The data suggest that ACTN3 is functionally redundant in humans and its loss is compensated for by the closely related ACTN2 (North et al., 1999). An example of network redundancy, as opposed to ...
... normal individuals very often shared the defective genotype, homozygous for a nonsense mutation to ACTN3. The data suggest that ACTN3 is functionally redundant in humans and its loss is compensated for by the closely related ACTN2 (North et al., 1999). An example of network redundancy, as opposed to ...
Hematology Final Copy2009-06-10 07:233.3 MB
... In HS the defect is in Actin, Ankyrin , and bind 3 α band 4.1 to allow the flexibility and convexity to RBCs. " that’s way they are destroyed in the spleen" The marrow produce red cells of normal biconcave shape BUT they loss membrane and become more and more spherical (loss of the surface area ...
... In HS the defect is in Actin, Ankyrin , and bind 3 α band 4.1 to allow the flexibility and convexity to RBCs. " that’s way they are destroyed in the spleen" The marrow produce red cells of normal biconcave shape BUT they loss membrane and become more and more spherical (loss of the surface area ...
Genetic Differences in Endothelial Cells May Determine
... incomplete penetrance reduces the power of linkage analysis by weakening the correlation between genotype and phenotype.”12 The small lesion size in the diet-induced mouse atherosclerosis model and the incomplete penetrance of lesions add to the difficulty of isolating genes for atherosclerosis susc ...
... incomplete penetrance reduces the power of linkage analysis by weakening the correlation between genotype and phenotype.”12 The small lesion size in the diet-induced mouse atherosclerosis model and the incomplete penetrance of lesions add to the difficulty of isolating genes for atherosclerosis susc ...
AZ188-08_FERTIG.qxd (Page 632)
... become generally used. This system determines malignancy by a scoring system that takes account of mitotic activity, any necrosis, and tumor differentiation. The total score gives the malignancy grade. However, not all sarcomas can be equally well assessed by this grading scheme. Some sarcomas have ...
... become generally used. This system determines malignancy by a scoring system that takes account of mitotic activity, any necrosis, and tumor differentiation. The total score gives the malignancy grade. However, not all sarcomas can be equally well assessed by this grading scheme. Some sarcomas have ...
The evolutionary causes and consequences of sex
... the sexes through the well-known process of dosage compensation. For this reason, the commonly observed enrichment of femalebiased genes on the X chromosome of wellstudied XY systems, such as mammals and Drosophila spp., has been attributed to factors other than gene dosage14–17. However, the situat ...
... the sexes through the well-known process of dosage compensation. For this reason, the commonly observed enrichment of femalebiased genes on the X chromosome of wellstudied XY systems, such as mammals and Drosophila spp., has been attributed to factors other than gene dosage14–17. However, the situat ...
Nature Genetics: doi:10.1038/ng.3791
... short sequence reads back to their location in a reference genome. Such sequence-specific biases in mapping can lead to artificial associations between genotype and any functional genomics measurements made with short read sequences3. A very effective method for addressing these biases is to identif ...
... short sequence reads back to their location in a reference genome. Such sequence-specific biases in mapping can lead to artificial associations between genotype and any functional genomics measurements made with short read sequences3. A very effective method for addressing these biases is to identif ...
PDF
... identified via plus/minus, microarray, SAGE or enhancer trapbased screens for genes expressed sex-differentially in the soma (Shirangi et al., 2009; Lebo et al., 2009; Chatterjee et al., 2011) (for reviews, see Christiansen et al., 2002; Camara et al., 2008). These screens identified dozens of genes ...
... identified via plus/minus, microarray, SAGE or enhancer trapbased screens for genes expressed sex-differentially in the soma (Shirangi et al., 2009; Lebo et al., 2009; Chatterjee et al., 2011) (for reviews, see Christiansen et al., 2002; Camara et al., 2008). These screens identified dozens of genes ...
Leukaemia Section T-lineage acute lymphoblastic leukemia (T-ALL) Atlas of Genetics and Cytogenetics
... TAL1 results in its ectopic expression via illegitimate recombinase activity. Also, misexpression of TAL1 has been observed in approximately 30% of patients who have T-ALL but no detectable TAL1 abnormality. Therefore, TAL1 protein is ectopically expressed in leukemic blast cells in as many as 60% o ...
... TAL1 results in its ectopic expression via illegitimate recombinase activity. Also, misexpression of TAL1 has been observed in approximately 30% of patients who have T-ALL but no detectable TAL1 abnormality. Therefore, TAL1 protein is ectopically expressed in leukemic blast cells in as many as 60% o ...
Ch14_Genetics
... When transfusing blood, a person’s blood type MUST be known and only certain types can be given… WHY? What blood type is the UNIVERSAL DONOR? What blood type is the UNIVERSAL ACCEPTOR? ...
... When transfusing blood, a person’s blood type MUST be known and only certain types can be given… WHY? What blood type is the UNIVERSAL DONOR? What blood type is the UNIVERSAL ACCEPTOR? ...
BLAST - AP Biology
... Between 1990-2003, scientists working on an international research project known as the Human Genome Project were able to identify and map the 20,000-25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escheri ...
... Between 1990-2003, scientists working on an international research project known as the Human Genome Project were able to identify and map the 20,000-25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escheri ...
Andreas Mock Cancer Research UK Cambridge Institute, University
... supplements of the latest publication (suppl_table_S1D.txt)2. ...
... supplements of the latest publication (suppl_table_S1D.txt)2. ...
Alcohol and Cancer Risk Key Points Heavy or regular alcohol
... grams of alcohol per day (approximately 3.5 or more drinks per day) have at least a two to three times greater risk of developing these cancers than nondrinkers (4). Moreover, the risks of these cancers are substantially higher among persons who consume this amount of alcohol and also use tobacco (5 ...
... grams of alcohol per day (approximately 3.5 or more drinks per day) have at least a two to three times greater risk of developing these cancers than nondrinkers (4). Moreover, the risks of these cancers are substantially higher among persons who consume this amount of alcohol and also use tobacco (5 ...
Understanding Evolutionary Relationships with
... Between 1990–2003, scientists working on an international research project known as the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escheri ...
... Between 1990–2003, scientists working on an international research project known as the Human Genome Project were able to identify and map the 20,000–25,000 genes that define a human being. The project also successfully mapped the genomes of other species, including the fruit fly, mouse, and Escheri ...
5 The Genetics of Bacteria and Their Viruses
... except T, which determines sensitivity or resistance to phage T1. The order of entry is as given, with arg+ entering the recipient first and Ts last. You find that the F– strain dies when exposed to penicillin (pens), but the Hfr strain does not (penr). How would you locate the locus for pen on the ...
... except T, which determines sensitivity or resistance to phage T1. The order of entry is as given, with arg+ entering the recipient first and Ts last. You find that the F– strain dies when exposed to penicillin (pens), but the Hfr strain does not (penr). How would you locate the locus for pen on the ...
PPR2263, a DYW-Subgroup Pentatricopeptide
... or chloroplasts, whereas no clear prediction is made for the rest. In addition to numerous experimental localizations in plastids and mitochondria, nuclear (Ding et al., 2006) or dual localization to mitochondria and nuclei (Hammani et al., 2011) has been demonstrated experimentally. Whereas PPR pro ...
... or chloroplasts, whereas no clear prediction is made for the rest. In addition to numerous experimental localizations in plastids and mitochondria, nuclear (Ding et al., 2006) or dual localization to mitochondria and nuclei (Hammani et al., 2011) has been demonstrated experimentally. Whereas PPR pro ...