Masters change, slaves remain
... Tra/Tra2-binding sites in and around the male-specific exons. If this model is correct, the role of Cctra in Ceratitis capitata would be similar to that of Sxl in the Drosophilids: it would be at the top of the sex determination hierarchy, directing female sexual development by regulating downstream ...
... Tra/Tra2-binding sites in and around the male-specific exons. If this model is correct, the role of Cctra in Ceratitis capitata would be similar to that of Sxl in the Drosophilids: it would be at the top of the sex determination hierarchy, directing female sexual development by regulating downstream ...
Human Nondisjunction and Mouse Models in Down Syndrome
... During mitosis, each chromosome consists of two sister chromatids, which stem from the preceding round of replication and are identical throughout their length. The regular segregation of chromosomes in mitosis, as well as bivalents in meiosis I, critically depends on their bipolar spindle attachmen ...
... During mitosis, each chromosome consists of two sister chromatids, which stem from the preceding round of replication and are identical throughout their length. The regular segregation of chromosomes in mitosis, as well as bivalents in meiosis I, critically depends on their bipolar spindle attachmen ...
Linkage and Recombination
... Note that the genes are linked; if they weren't, we would have 8 phenotypes and 8 gamete genotypes in approximately equal numbers. Arranged in pairs of equal numbers, in order of magnitude. Which are parental genotypes? Which are double crossover genotypes? ...
... Note that the genes are linked; if they weren't, we would have 8 phenotypes and 8 gamete genotypes in approximately equal numbers. Arranged in pairs of equal numbers, in order of magnitude. Which are parental genotypes? Which are double crossover genotypes? ...
Efficient TALEN-mediated gene targeting of chicken
... Here we use TALENs to knockout the DDX4 (CVH (vasa)) locus in chickens with the aim to demonstrate efficient targeting of genes important for development of the germ cell lineage. TALE (transcriptional activator-like effectors) nucleases (TALENs) are synthetic transcription factors that can be modul ...
... Here we use TALENs to knockout the DDX4 (CVH (vasa)) locus in chickens with the aim to demonstrate efficient targeting of genes important for development of the germ cell lineage. TALE (transcriptional activator-like effectors) nucleases (TALENs) are synthetic transcription factors that can be modul ...
Retina International Congress 2014 Summary
... be able to give a genetic diagnosis for a foetus but this would rely on a very clear genetic diagnosis, and this would be complex and expensive. Dr Rozet explained that he used Sangers sequencing tool, but this can only investigate 1000 genes at the one time. However the cost of Exome gene screenin ...
... be able to give a genetic diagnosis for a foetus but this would rely on a very clear genetic diagnosis, and this would be complex and expensive. Dr Rozet explained that he used Sangers sequencing tool, but this can only investigate 1000 genes at the one time. However the cost of Exome gene screenin ...
A Mathematical Model for Solving Four Point Test Cross in Genetics
... testcross cannot be applied in case of four point testcross, as there is more than one gene in the middle, so a new approach for finding the same for four point test cross is needed. By this approach the reader can not only map the four point test cross but also map the n-point test cross data and h ...
... testcross cannot be applied in case of four point testcross, as there is more than one gene in the middle, so a new approach for finding the same for four point test cross is needed. By this approach the reader can not only map the four point test cross but also map the n-point test cross data and h ...
Partial Sequence Analysis of the 5S to 18S rRNA Gene Region of
... plant mitochondria, rRNA genes are larger and a 5S RNA is found in mitochondrial ribosomes (6, 15). The 5S and 18S rRNA genes in plant mtDNA are closely linked (3, 10, 12), but both are separate from the 26S rRNA gene (24). In maize, the 26S rRNA gene is separated from the 18S and 5S by 16,000 base ...
... plant mitochondria, rRNA genes are larger and a 5S RNA is found in mitochondrial ribosomes (6, 15). The 5S and 18S rRNA genes in plant mtDNA are closely linked (3, 10, 12), but both are separate from the 26S rRNA gene (24). In maize, the 26S rRNA gene is separated from the 18S and 5S by 16,000 base ...
Review Molecular Biology in Arteriosclerosis Research
... dramatic Impact on arteriosclerosis research. DNA clones for a small number of relevant proteins have been isolated, and studies are underway in numerous laboratories to extend these initial studies. The techniques of molecular biology will provide major advances in our understanding of numerous pro ...
... dramatic Impact on arteriosclerosis research. DNA clones for a small number of relevant proteins have been isolated, and studies are underway in numerous laboratories to extend these initial studies. The techniques of molecular biology will provide major advances in our understanding of numerous pro ...
Leukaemia Section t(3;12)(q26;p13) ETV6/MECOM / t(3;12)(q26;p13) ETV6/EVI1 Atlas of Genetics and Cytogenetics
... The ETV6 gene spans a region of less than 250 kb at band 12p13.1 and consists of 8 exons. There are two start codons, one (exon 1a starting at codon 1) located at the beginning of the gene and another alternative (exon 1b starting at codon 43) upstream of exon 3. Protein The ETV6 protein (452 amino ...
... The ETV6 gene spans a region of less than 250 kb at band 12p13.1 and consists of 8 exons. There are two start codons, one (exon 1a starting at codon 1) located at the beginning of the gene and another alternative (exon 1b starting at codon 43) upstream of exon 3. Protein The ETV6 protein (452 amino ...
- bioRxiv
... stochastic gene expression variation. An intrinsic contribution resulting from stochasticity of biochemical processes, including factors such as transcriptional bursting and gene copy number; and an extrinsic component, which arises from subtle environmental differences, cell-cell communication, or ...
... stochastic gene expression variation. An intrinsic contribution resulting from stochasticity of biochemical processes, including factors such as transcriptional bursting and gene copy number; and an extrinsic component, which arises from subtle environmental differences, cell-cell communication, or ...
Marine integrons containing novel integrase genes
... gene to the promoter, Pc, its expression level is the highest among other integron-associated gene cassettes (Collis and Hall, 1995). Thus, this gene cassette is a good target to find new strongly expressed adaptive genes in metagenomes (Huang et al., 2009). This study had two aims. The first one wa ...
... gene to the promoter, Pc, its expression level is the highest among other integron-associated gene cassettes (Collis and Hall, 1995). Thus, this gene cassette is a good target to find new strongly expressed adaptive genes in metagenomes (Huang et al., 2009). This study had two aims. The first one wa ...
Transcriptional analysis of the gene for glutamine synthetase II and
... glnII) activity detectable in crude extracts from Streptomyces coelicolor is low compared to the activity of glutamine synthetase I (GSI, encoded by glnA) and to that of GSII from S. viridochromogenes. We have identi®ed and sequenced a 3.9-kb BglII-BamHI fragment carrying the glutamine synthetase II ...
... glnII) activity detectable in crude extracts from Streptomyces coelicolor is low compared to the activity of glutamine synthetase I (GSI, encoded by glnA) and to that of GSII from S. viridochromogenes. We have identi®ed and sequenced a 3.9-kb BglII-BamHI fragment carrying the glutamine synthetase II ...
Gene Section FANCF (Fanconi anemia, complementation group F)
... FANCA and FANCG form a complex in the cytoplasm, through a N-term FANCA (involving the nuclear localization signal) - FANCG interaction; FANCC join the complex; phosphorylation of FANCA would induce its translocation into the nucleus.This FA complex translocates into the nucleus, where FANCE and FAN ...
... FANCA and FANCG form a complex in the cytoplasm, through a N-term FANCA (involving the nuclear localization signal) - FANCG interaction; FANCC join the complex; phosphorylation of FANCA would induce its translocation into the nucleus.This FA complex translocates into the nucleus, where FANCE and FAN ...
Genetics and Biotechnology
... Why is polymerase chain reaction (PCR) one of the most powerful tools used by scientists? A. It can be used to identify errors in DNA sequences and predict the function of genes. B. It can detect a single DNA molecule in a sample and make millions of copies of it. C. It creates large amounts of reco ...
... Why is polymerase chain reaction (PCR) one of the most powerful tools used by scientists? A. It can be used to identify errors in DNA sequences and predict the function of genes. B. It can detect a single DNA molecule in a sample and make millions of copies of it. C. It creates large amounts of reco ...
fliD operon of Salmonella typhimurium
... This work was initiated to elucidate the function of the genes in the fliD operon of S. t_yphimzlrizlm in flagellar morphogenesis. For understanding the function of specific genes, it is important to isolate defined mutants defective in the genes. Using the gene-replacement method developed by Yamad ...
... This work was initiated to elucidate the function of the genes in the fliD operon of S. t_yphimzlrizlm in flagellar morphogenesis. For understanding the function of specific genes, it is important to isolate defined mutants defective in the genes. Using the gene-replacement method developed by Yamad ...
Global MAPS Metabolomic Assisted Pathway Screen
... The Proband Whole Exome Sequencing test is a highly complex test that is newly developed for the identification of changes in a patient’s DNA that are causative or related to their medical concerns. In contrast to current sequencing tests that analyze one gene or small groups of related genes at a t ...
... The Proband Whole Exome Sequencing test is a highly complex test that is newly developed for the identification of changes in a patient’s DNA that are causative or related to their medical concerns. In contrast to current sequencing tests that analyze one gene or small groups of related genes at a t ...
Determination of the molecular basis of Marfan syndrome: a growth
... related phenotype, even though the abnormal human molecule appears to be incorporated into microfibril structures along with the endogenous murine fibrillin-1 molecules with which the human molecules interact. Second, they observed that the human FBN1 gene appears to rescue the Marfan syndrome–like ...
... related phenotype, even though the abnormal human molecule appears to be incorporated into microfibril structures along with the endogenous murine fibrillin-1 molecules with which the human molecules interact. Second, they observed that the human FBN1 gene appears to rescue the Marfan syndrome–like ...
Epigenetics - Institute for Cancer Genetics
... in” epigenetic states. However, regulating metastable states of gene expression is so crucial in development and tissue homeostasis that other mechanisms, in addition to histone modifications and DNA methylation, come into play to establish and maintain epigenetic states. Regulatory non-coding RNAs ...
... in” epigenetic states. However, regulating metastable states of gene expression is so crucial in development and tissue homeostasis that other mechanisms, in addition to histone modifications and DNA methylation, come into play to establish and maintain epigenetic states. Regulatory non-coding RNAs ...
22 Fungal Genetics Newsletter bimD
... Such bimD function differs from that of members in the four Uvs epistatic groups of A. nidulans which increasingly is becoming better defined [superceding even recent reviews; e. g., Kafer and May 1998 In Nickoloff and Hoekstra (eds), DNA Damage and Repair, vol.1, Humana, Totowa NJ, p. 477-502]. Cur ...
... Such bimD function differs from that of members in the four Uvs epistatic groups of A. nidulans which increasingly is becoming better defined [superceding even recent reviews; e. g., Kafer and May 1998 In Nickoloff and Hoekstra (eds), DNA Damage and Repair, vol.1, Humana, Totowa NJ, p. 477-502]. Cur ...
Challenge Problems 2 - AHS
... Linked genes are found on the same chromosome, and are therefore usually inherited together. Linked genes may be separated from one another if crossing over occurs between homologous chromosomes. The closer together two genes are on a chromosome, the less frequently crossing over will occur between ...
... Linked genes are found on the same chromosome, and are therefore usually inherited together. Linked genes may be separated from one another if crossing over occurs between homologous chromosomes. The closer together two genes are on a chromosome, the less frequently crossing over will occur between ...
cancer/testis antigens, gametogenesis and cancer
... well as splice variants, such as XAGE1a and XAGE1b, resulting in a total of 89 transcripts (TABLES 1,2 and BOX 1). In order for a protein to be designated a CT antigen, it must be expressed in tumours as well as in testis and/or the placenta, but not be expressed in more than two non-germline normal ...
... well as splice variants, such as XAGE1a and XAGE1b, resulting in a total of 89 transcripts (TABLES 1,2 and BOX 1). In order for a protein to be designated a CT antigen, it must be expressed in tumours as well as in testis and/or the placenta, but not be expressed in more than two non-germline normal ...
Supercoils in plant DNA: nucleoid
... upper curve). There is however a substantial feature distinguishing the plant nucleoid behaviour from that observed in the animal systems and it concerns the magnitude of the difference between the maximum ...
... upper curve). There is however a substantial feature distinguishing the plant nucleoid behaviour from that observed in the animal systems and it concerns the magnitude of the difference between the maximum ...
Speciation - Trimble County Schools
... Single-Gene and Polygenic Traits The number of phenotypes produced for a given trait depends on how many genes control the trait. ...
... Single-Gene and Polygenic Traits The number of phenotypes produced for a given trait depends on how many genes control the trait. ...