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Intra-isolate genome variation in arbuscular mycorrhizal
Intra-isolate genome variation in arbuscular mycorrhizal

... between nuclei within AMF isolates has thus far been studied using two distinct approaches. First, the presence of different alleles, and variation in copy number between nuclei of a single isolate, has been visualized using FISH techniques for ribosomal (ITS, Kuhn et al., 2001) and protein-coding l ...
EFFECT OF FSH β-SUB UNIT AND FSHR GENES
EFFECT OF FSH β-SUB UNIT AND FSHR GENES

... n = number of sample, na = not analyzed, * = significantly different at χ20.05 ...
Plants in Action
Plants in Action

... (c)??Determination of shoot meristem and organ identity Genes controlling meristem identity What determines whether a meristem is vegetative or re-productive has long been a vexing question. Now, by using molecular technology and studying the transition of meristems from vegetative to reproductive i ...
Genetics of Cancer
Genetics of Cancer

... There are more than 100 oncogenes – Cause cancer when they are inappropriately activated More than 30 tumor suppressor genes whose deletion or inactivation causes cancer Cancer is a consequence of disruption of the cell cycle – The cell divides more frequently or more times – Timing, rate, and numbe ...
Molecular diagnostics of mitochondrial disorders
Molecular diagnostics of mitochondrial disorders

... genes, as well as other nuclear genes. DHPLC can sometimes detect only one abnormal profile corresponding to a heterozygous mutation. Direct sequencing of the complete coding sequence has to be performed to identify the second mutation which was undetected by the DHPLC, whereas several conditions of ...
Male-to-male transmission of X-linked Alport syndrome in a
Male-to-male transmission of X-linked Alport syndrome in a

... patterns of X chromosome inactivation. Guo et al21 reported a severe phenotype in a woman with X-linked AS and demonstrated over 90% inactivation of the wildtype allele in both white blood cells and renal parenchyma. In contrast, no correlation between the severity of the disease and the X-inactivat ...
appENDIX I - VU Research Portal
appENDIX I - VU Research Portal

... certain combination of 8 allele calls in the DTNBP1 (dystrobrevin binding protein 1) gene were unique for the disease group (Van den Oord et al., 2003). Human individuals differ from one another by about one base pair per thousand. If these differences occur within coding or regulatory regions, phen ...
Genome-wide expression screens indicate a global role for protein
Genome-wide expression screens indicate a global role for protein

... cells (Lorenz et al., 1993; Pepperkok et al., 1993; Pepperkok et al., 1994). Rather, according to their peak expression (Spellman et al., 1998; Cho et al., 1998), the genes can be assigned to various cell cycle stages. Aside from affected early genes (37 M/G1 phase and 95 G1 phase genes), genes ascr ...
Additional file 4 - Springer Static Content Server
Additional file 4 - Springer Static Content Server

... relatives could be tested readily by targeted molecular analysis. Balanced translocations between chromosome centromeres and/or involving other repetitive chromosome heteromorphisms including 1qH, 9qH, and 16qH are likely to be the overlooked given the regions of repetitive sequences on both sides o ...
Nucleotide Bias Causes a Genomewide Bias in the Amino Acid
Nucleotide Bias Causes a Genomewide Bias in the Amino Acid

... on individual genes in more detail, we decided to compare the two genomes with the most distinct nucleotide compositions available. We identified the genes in common between the genomes of the highly AT-rich genome of B. burgdorferi and the very GC-rich genome of M. tuberculosis in an analysis simil ...
Gene Section BEX1 (brain expressed, X-linked 1) Atlas of Genetics and Cytogenetics
Gene Section BEX1 (brain expressed, X-linked 1) Atlas of Genetics and Cytogenetics

... reactivated by trichostatin A (TSA), a histone deacetylase inhibitor, or 5-aza-2'-deoxycytidine (5AzaC), a DNA methyltransferase inhibitor in glioma cell line T98 and U87, and 10 patient-derived primary glioma cell lines (Foltz et al., 2006). We demonstrated that BEX1 and BEX2's expression were sile ...
Markov Chain and Stationary distributions
Markov Chain and Stationary distributions

... denoted strains. Each row represents a given gene and each column represents a different strain, color-coded as described in Figure 1. (A) Expression patterns of 2,680 genes that varied significantly (FDR= 0.01, paired t-test) in at least one strain compared to S288c. (B) Expression patterns of 953 ...
RNA Processing in Eukaryotes
RNA Processing in Eukaryotes

... (methyl functional group) is added for stability. Pre-tRNA molecules also undergo methylation. As with pre-mRNAs, subunit excision occurs in eukaryotic pre-RNAs destined to become tRNAs or rRNAs. Mature rRNAs make up approximately 50 percent of each ribosome. Some of a ribosome's RNA molecules are p ...
My favourite flowering image: a cob of pod corn
My favourite flowering image: a cob of pod corn

... the Tunicate story, it reported results almost a decade before they were actually published so that ‘preview’ would have been a more appropriate term. In the same year we submitted the sequence of ZMM19 from Tunicate to GenBank. This obviously helped others to uncover the molecular basis of the Tuni ...
Chapter 8 Human Chromosomes
Chapter 8 Human Chromosomes

... as a standard representation of the chromodivide and become two cells it must undergo DNA replication. This doubles the DNA content to 4C = 12 somes in a cell, organism, or species. Comparisons 000 Mb. When the zygote does divide, each daughter permit them to identify chromosome abnormalities. cell ...
Both parents affected
Both parents affected

... be associated with alleles which stop a gene product from being produced. The heterozygotes are postulated to have half the normal concentration of the gene product whilst homozygous affected individuals make none. ...
FAQs (frequently asked questions) Q.1 What are plasmids? Ans
FAQs (frequently asked questions) Q.1 What are plasmids? Ans

... XmaIII and Nrul, are located within the genes coding for tetracycline resistance; two sites for HindIII and CIa I lie within the promoter of the tetracycline resistance gene; and three sites for PstI, PvuI and Sca l lie within the β-lactamase gene. Cloning of a DNA fragment into any of these 11 site ...
No Slide Title
No Slide Title

... Cancer research Cancer typing Correlating whole-genome expression pattern with particular clinical implication ...
bbr038online 474..484 - Oxford Academic
bbr038online 474..484 - Oxford Academic

... conducted even by individual laboratories. However, this will yield more and more genome sequences that are not well assembled, and will hinder thorough annotation when no closely related reference genome is available. One of the challenging issues is the identification of protein-coding sequences s ...
Print - Circulation Research
Print - Circulation Research

... Recently, we have demonstrated the expression of nonmuscle myosin in restenotic lesions in human coronary as well as peripheral arteries.25 The appearance of the nonmuscle isoform correlates with the newly acquired ability of smooth muscle cells to divide and disappears when cells return to their co ...
Crystal structures of -[Ru(phen)2dppz]2+ 1 with oligonucleotides
Crystal structures of -[Ru(phen)2dppz]2+ 1 with oligonucleotides

... Description of the structures Complex between 1 and d(CCGGTACCGG) This self-complementary sequence crystallizes to give a symmetrical duplex with a stoichiometry of three cations of 1 per duplex, or 1.5 cations of 1 per decamer strand. All the nucleic acid strands are equivalent in the crystal latt ...
Slides
Slides

... – Converted to DNA and integrate into genome with help of RNA reverse transcriptase and integrase enzymes and long tandem repeats (LTRs) – Transcribed into RNA and produce virus (example HIV) ...
Laws of Inheritance
Laws of Inheritance

... round/yellow:3 round/green:3 wrinkled/yellow:1 wrinkled/green (Figure 2). These are the ospring ratios we would expect, assuming we performed the crosses with a large enough sample size. Because of independent assortment and dominance, the 9:3:3:1 dihybrid phenotypic ratio can be collapsed into two ...
Document
Document

... A child who inherits the genes bb will have blue eyes In the F2 generation the ratio of brown eyed children to blue eyes will be 3 to 1 ...
REVIEW ARTICLE Gene cassettes
REVIEW ARTICLE Gene cassettes

... classes of integron are currently known, all of which appear to be able to integrate the same set of cassettes. However, cassettes are also found rarely at non-specific sites. They move by conservative site-specific recombination catalysed by an integrase encoded by the recipient integron, and thus ...
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Therapeutic gene modulation

Therapeutic gene modulation refers to the practice of altering the expression of a gene at one of various stages, with a view to alleviate some form of ailment. It differs from gene therapy in that gene modulation seeks to alter the expression of an endogenous gene (perhaps through the introduction of a gene encoding a novel modulatory protein) whereas gene therapy concerns the introduction of a gene whose product aids the recipient directly.Modulation of gene expression can be mediated at the level of transcription by DNA-binding agents (which may be artificial transcription factors), small molecules, or synthetic oligonucleotides. It may also be mediated post-transcriptionally through RNA interference.
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