Ultraconserved Elements in the Human Genome
... with chicken and other species are often not in multiples of three, giving further evidence that these sequences are noncoding (fig. S1, A and B,b). The ultraconserved elements we found in introns seem to have been at one time rather fast-evolving compared to the known coding exons in their genes. W ...
... with chicken and other species are often not in multiples of three, giving further evidence that these sequences are noncoding (fig. S1, A and B,b). The ultraconserved elements we found in introns seem to have been at one time rather fast-evolving compared to the known coding exons in their genes. W ...
PDF
... expression are broadly conserved, but the precise limits of expression are not the same as those in Drosophila. For example, the Abd-B genes in Tribolium and Schistocerca appear to be expressed in the epidermis of only the most posterior abdominal segments (from A8p back; Kelsh et al., 1993; J. He & ...
... expression are broadly conserved, but the precise limits of expression are not the same as those in Drosophila. For example, the Abd-B genes in Tribolium and Schistocerca appear to be expressed in the epidermis of only the most posterior abdominal segments (from A8p back; Kelsh et al., 1993; J. He & ...
Full Text - Harvard University
... Phenotype. Genotype refers to the all the genetic information that constitutes an organism. Phenotype refers to all the observable traits or characteristics of that organism. Considering gene expression as an observable trait, the main focus of all the reverse engineering methods is to model the com ...
... Phenotype. Genotype refers to the all the genetic information that constitutes an organism. Phenotype refers to all the observable traits or characteristics of that organism. Considering gene expression as an observable trait, the main focus of all the reverse engineering methods is to model the com ...
Genetics- Part 1- Genes
... F2 genotype ratio = 1:2:1 (1FF : 2Ff : 1ff) phenotype ratio = 3:1 (3full: 1 constricted) Alleles and Loci An allele is a gene that has more than one form. Each of the forms is referred to as an allele. For example, the gene for red flowers and the gene for white flowers are two different alleles. A ...
... F2 genotype ratio = 1:2:1 (1FF : 2Ff : 1ff) phenotype ratio = 3:1 (3full: 1 constricted) Alleles and Loci An allele is a gene that has more than one form. Each of the forms is referred to as an allele. For example, the gene for red flowers and the gene for white flowers are two different alleles. A ...
Peer-reviewed Article PDF
... reduced this phenylalanine-binding capacity. The data suggested that impairment of phenylalanine-mediated activation of PAH may be an important disease-causing mechanism of some N-terminal PAH mutations. Most missense mutations found in PKU result in misfolding of the phenylalanine hydroxylase prote ...
... reduced this phenylalanine-binding capacity. The data suggested that impairment of phenylalanine-mediated activation of PAH may be an important disease-causing mechanism of some N-terminal PAH mutations. Most missense mutations found in PKU result in misfolding of the phenylalanine hydroxylase prote ...
Physiological and phylogenetic analysis of rhizobia isolated from
... were non-symbiotic. Therefore, only two symbiotic rhizobia strains were selected for phyolgenetic analysis to 16S r-RNA sequencing. The 16S r-RNA gene is useful for characterization because it is slowly evolving and the gene product is both universally essential and functionally conserved. For this, ...
... were non-symbiotic. Therefore, only two symbiotic rhizobia strains were selected for phyolgenetic analysis to 16S r-RNA sequencing. The 16S r-RNA gene is useful for characterization because it is slowly evolving and the gene product is both universally essential and functionally conserved. For this, ...
Sex determination in Bombyx mori
... OD2 domain is known to be necessary for the oligomerization of DSX and is supposed to be related to DNAbinding cooperativity when the proteins bind regulatory sites in target DNA40 . Thus, BmDSX would also bind to target DNA by forming oligomers. Although the actual expression level of Bmdsx mRNA wa ...
... OD2 domain is known to be necessary for the oligomerization of DSX and is supposed to be related to DNAbinding cooperativity when the proteins bind regulatory sites in target DNA40 . Thus, BmDSX would also bind to target DNA by forming oligomers. Although the actual expression level of Bmdsx mRNA wa ...
The Genetics of Alcohol Metabolism
... coding sequences, which are those parts of the gene that actually serve as templates for protein production, are called exons. The intervening noncoding sequences are known as introns (see Figure). In addition to the exons and introns, genes contain regulatory sequences that determine in which cell, ...
... coding sequences, which are those parts of the gene that actually serve as templates for protein production, are called exons. The intervening noncoding sequences are known as introns (see Figure). In addition to the exons and introns, genes contain regulatory sequences that determine in which cell, ...
The HSP90 family of genes in the human genome
... from database searches, 64 mRNAs and 41 protein sequences came from different submissions and were confirmed to belong to the family through similarity comparison after sequence alignment. Thirty-six of these protein sequences were originally submitted to the GenBank/EMBL Data Libraries with an acco ...
... from database searches, 64 mRNAs and 41 protein sequences came from different submissions and were confirmed to belong to the family through similarity comparison after sequence alignment. Thirty-six of these protein sequences were originally submitted to the GenBank/EMBL Data Libraries with an acco ...
Full Text PDF - Journal of Integrative Plant Biology
... electron microscopy (SEM), and genetic analysis indicated that mutant traits were controlled by single recessive gene (temporarily designated as lh). The possible relationships between this lh gene and other floral organ mutants reported earlier in rice are discussed. Furthermore, we deduced that th ...
... electron microscopy (SEM), and genetic analysis indicated that mutant traits were controlled by single recessive gene (temporarily designated as lh). The possible relationships between this lh gene and other floral organ mutants reported earlier in rice are discussed. Furthermore, we deduced that th ...
Molecules and morphology: where`s the homology?
... The terminology used in this article to describe rehtionships is that proposed by Fitch16, elaborated by Patterson17, and summarized in the instructions to authors writing for Molecular Biology and Evolution. Briefly, features (including molecules) that are similar by virtue of common ancestry are h ...
... The terminology used in this article to describe rehtionships is that proposed by Fitch16, elaborated by Patterson17, and summarized in the instructions to authors writing for Molecular Biology and Evolution. Briefly, features (including molecules) that are similar by virtue of common ancestry are h ...
Interference Do crossovers interefere with one another? Or, if a
... maximum likelihood ratios (a statistical method for estimation). The approach of using Lod scores, involves determining the probability of observing a particular set of progeny for a single family first assuming the two genes are not linked (i.e. assume independent assortment). It is then possible t ...
... maximum likelihood ratios (a statistical method for estimation). The approach of using Lod scores, involves determining the probability of observing a particular set of progeny for a single family first assuming the two genes are not linked (i.e. assume independent assortment). It is then possible t ...
BiGCaT
... and map expression results Example QTL1a With a number of (slightly) upregulated genes ...
... and map expression results Example QTL1a With a number of (slightly) upregulated genes ...
Gene regulation_1130(final)
... • Insulin affects transcription, mRNA stability, and translation (from gene to protein) • Focusing on insulin-regulated gene transcription – Positive and negative effects on the transcription of specific genes even within the same cell. – Insulin-regulated genes coding proteins involved in a varie ...
... • Insulin affects transcription, mRNA stability, and translation (from gene to protein) • Focusing on insulin-regulated gene transcription – Positive and negative effects on the transcription of specific genes even within the same cell. – Insulin-regulated genes coding proteins involved in a varie ...
uniprotkb-goa_aug2011
... • Most popular type of GO analysis • Determines which GO terms are more often associated with a specified list of genes/proteins compared with a control list or rest of genome • Many tools available to do this analysis • User must decide which is best for their analysis ...
... • Most popular type of GO analysis • Determines which GO terms are more often associated with a specified list of genes/proteins compared with a control list or rest of genome • Many tools available to do this analysis • User must decide which is best for their analysis ...
2) TF Gene-Disease Association Property Predictions
... integrate and evaluate the strength of the links between genes, evidence and disease. This divides the linkages into five broad categories: Gene-Gene, Gene-Evidence, EvidenceEvidence, Evidence-Disease and Disease-Disease. Gene-Gene relationships include homology and gene interactions. When consideri ...
... integrate and evaluate the strength of the links between genes, evidence and disease. This divides the linkages into five broad categories: Gene-Gene, Gene-Evidence, EvidenceEvidence, Evidence-Disease and Disease-Disease. Gene-Gene relationships include homology and gene interactions. When consideri ...
An Investigation of Codon Usage Bias Including
... in translating the mRNA transcripts into the protein macromolecules. When the codon associated with the highest tRNA abundance is utilized, efficiencies in translation can be realized due to the higher relative availability. Biases associated with translational efficiency are not the only biases fou ...
... in translating the mRNA transcripts into the protein macromolecules. When the codon associated with the highest tRNA abundance is utilized, efficiencies in translation can be realized due to the higher relative availability. Biases associated with translational efficiency are not the only biases fou ...
An eye on trafficking genes: identification of four eye color mutations
... substances needed for pigment synthesis are transported to the pigment granule, a lysosomerelated organelle (Dell'Angelica et al. 2000; Reaume et al. 1991; Summers et al. 1982). D. melanogaster has a red-brown eye color caused by the presence of two classes of pigments, pteridines (red) and ommochro ...
... substances needed for pigment synthesis are transported to the pigment granule, a lysosomerelated organelle (Dell'Angelica et al. 2000; Reaume et al. 1991; Summers et al. 1982). D. melanogaster has a red-brown eye color caused by the presence of two classes of pigments, pteridines (red) and ommochro ...
Allele- and parent-of-origin-specific effects on expression of the
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
... OTAGO database, which contains data on imprinted genes and their related effects (http://igc. otago.ac.nz/). Currently in this database, only 34 bovine genes have been found to be imprinted or non-imprinted whereas 332 and 228 entries exist for human and mouse, respectively. Since 2011, the number o ...
ATP16 Genes and Neighboring ORFs Are Duplicated on
... al., 2003). The total DNAs (genomic DNAs) of the ATP16-disruptants derived from four different laboratory strains, DC5, LL20, W303-1A, and W303-1B, were digested with HincII, transferred on membranes, and then hybridized successively with DIG-labeled (a) ATP16 and (b) yeast HIS3 as probes. The DNAs ...
... al., 2003). The total DNAs (genomic DNAs) of the ATP16-disruptants derived from four different laboratory strains, DC5, LL20, W303-1A, and W303-1B, were digested with HincII, transferred on membranes, and then hybridized successively with DIG-labeled (a) ATP16 and (b) yeast HIS3 as probes. The DNAs ...
Analysis of GDSL lipase (GLIP) family genes in rice (Oryza sativa)
... thirteen GILP genes were obtained (latest data). The comparison with Volokita et al. (2011) research shows that 108 genes were identical, while others had discrepancy. To investigate the contribution of gene duplication in the expansion of GILP gene family, the chromosomal location of each GILP gene ...
... thirteen GILP genes were obtained (latest data). The comparison with Volokita et al. (2011) research shows that 108 genes were identical, while others had discrepancy. To investigate the contribution of gene duplication in the expansion of GILP gene family, the chromosomal location of each GILP gene ...
Warren-Proposal-Mining-TF-Genes-Disease-2007-07
... G2D(Perez-Iratxeta, Bork et al. 2002) links genes from a specified genomic locus to diseases by examining PubMed MeSH disease and chemical term annotation and RefSeq GO annotations. MeSH disease terms were mapped to MeSH chemical terms via co-occurring annotation of PubMed articles. RefSeq GO annota ...
... G2D(Perez-Iratxeta, Bork et al. 2002) links genes from a specified genomic locus to diseases by examining PubMed MeSH disease and chemical term annotation and RefSeq GO annotations. MeSH disease terms were mapped to MeSH chemical terms via co-occurring annotation of PubMed articles. RefSeq GO annota ...
1 - life.illinois.edu
... auxotroph and the second contains a TS mutation in the rpoA gene that codes for the alpha subunit of RNA polymerase. a.) Which mutation is most likely to affect an essential function? Why? Answer: A functional rpoA is required for transcription and hence for growth under any conditions. Functional l ...
... auxotroph and the second contains a TS mutation in the rpoA gene that codes for the alpha subunit of RNA polymerase. a.) Which mutation is most likely to affect an essential function? Why? Answer: A functional rpoA is required for transcription and hence for growth under any conditions. Functional l ...
How to use KAIKObase: An integrated silkworm genome database
... KAIKObase is an integrated silkworm genome browser with 4 map browsers, 1 gene viewer, and 2 independent databases. * PGmap : physical map and genetic linkage map for each chromosome. * UnifiedMap : PGmap containing genome contigs, BAC-ends, fosmid-ends, and Fingerprint Contigs (FPC). * UTGB : genom ...
... KAIKObase is an integrated silkworm genome browser with 4 map browsers, 1 gene viewer, and 2 independent databases. * PGmap : physical map and genetic linkage map for each chromosome. * UnifiedMap : PGmap containing genome contigs, BAC-ends, fosmid-ends, and Fingerprint Contigs (FPC). * UTGB : genom ...