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Section 2 - Introduction to Molecular Biology
Section 2 - Introduction to Molecular Biology

... catalysed by DNA polymerase- this causes the chain to elongate, but it can’t start the formation of a new chain. For this a primer (short piece of DNA/ RNA) is required. ...
Vibrio Cholera
Vibrio Cholera

... Expression of CT & TCP have been shown in vitro to be strongly influenced by changes in cultural conditions ie. temperature, pH, osmolarity, & growth medium composition CT & TCP are regulated via a cascade in which ToxR and TcpP control expression of ToxT, which is a transcriptional activator direct ...
Genetics
Genetics

... 4. Some genes are dominant, whereas other genes are recessive. 5. Dominant genes hide recessive genes when both are inherited by an organism. 6. Some genes are neither dominant nor recessive. These genes show incomplete dominance. ...
Local BLAST - For link to GMS6014, click here
Local BLAST - For link to GMS6014, click here

... Search for MDM2 in “All Text” v.s “gene name” in the Gene database. Compare results. Download the human MDM2 protein sequences for all 8 isoforms. ...
GeneFarm, structural and functional annotation of Arabidopsis gene
GeneFarm, structural and functional annotation of Arabidopsis gene

... Performing a gene family-based annotation makes the task easier and more efficient than a gene-by-gene approach. Indeed, due to their common origin, genes from the same family quite often share the same gene intron–exon structure. Furthermore, sequence comparisons of all the members of a protein fam ...
This project aims to investigate the use of Petri Nets to model
This project aims to investigate the use of Petri Nets to model

... regulatory systems. Developments in post-genomic technology are providing genome wide data enabling the holistic modelling of complex cellular regulatory systems. In particular gene-expression arrays and new proteomics techniques are producing large datasets from studies of molecular processes. New ...
Cystic Fibrosis
Cystic Fibrosis

...  Besides the most common mutation, ΔF508, accounting for about 70% of CF chromosomes worldwide, more than 850 mutant alleles have been reported to the CF Genetic Analysis Consortium.  These mutations affect CFTR through a variety of molecular mechanisms which can produce little or no functional CF ...
Lecture 6
Lecture 6

... intervals between genes had to contain vast amounts of DNA. These gaps could not be mapped by linkage analysis, because there were no markers in those regions. ...
RNA interference and its role in the regulation of eucaryotic gene
RNA interference and its role in the regulation of eucaryotic gene

... Several years ago it was discovered that plant transformation with a transcribed sense transgene could shut down the expression of a homologous endogenous gene. Moreover, it was shown that the introduction into the cell of dsRNA (double-stranded RNA) containing nucleotide sequence complementary to a ...
Chapter 9: Patterns of Inheritance
Chapter 9: Patterns of Inheritance

... F1 generation ...
A Web based Database for Hypothetical Genes in the Human Genome
A Web based Database for Hypothetical Genes in the Human Genome

... annotation which involves identification of genes within the chromosome, its fine structure, determination of protein products encodes by the gene and understanding the function (Venter et al., 2001). A group of these genes may be involved in many pathological disorders and hence are of pharmaceutic ...
Population Genetics in the Post
Population Genetics in the Post

... Experimental crosses: Crosses in controlled setting. •Typically, these collections are hypothesis driven. •The challenge is to collect data so that the resulting analysis will have enough power. ...
cinnabar - UWL faculty websites
cinnabar - UWL faculty websites

... chromosomes lack cn function as well as that of one or more flanking lethal complementation groups (Alexandrov, 1984; Alexandrov & Alexandrov, 1991; Lindsley & Zimm, 1992; Wustmann et al., 1989). Radiolabelled DNA prepared from the )tG3 clone was found to hybridize to Df( 2R )CA5 31CyO and Df( 2R )c ...
Genetics Terminology
Genetics Terminology

... Look at the offspring of the test cross to determine if it is heter or homozygous. ...
Traits and Inheritance - Birmingham City Schools
Traits and Inheritance - Birmingham City Schools

... • In pea plants, possible phenotypes for the characteristic of flower color would be purple flowers or white flowers. • Phenotypes of humans are much more complicated than those of peas. ExampleAlbinism prevents hair, skin, and eyes from ...
Appendix S1.
Appendix S1.

... pseudo, putative or hypothetical genes (genes that are non-functional or not protein-coding). Extensive literature search was done. Genes were given higher credits and corresponding prioritization if there were evidences for relevant biological functions, involvement as structural constituents or in ...
15.1 and 15.2 notes: -Law of segregation – Homologous
15.1 and 15.2 notes: -Law of segregation – Homologous

... 50% frequency of recombination seen for any two genes located on different chromosomes. This is due to the random orientation of homologous chromosomes at metaphase of meiosis I and separation during Anaphase I resulting in independent assortment of alleles (Fig. 15.2). Morgan’s student Alfred Sturt ...
I. Comparing genome sequences
I. Comparing genome sequences

... •Infer the course of past evolution using statistical models of sequence evolution •Identify sequence elements evolving more slowly or more rapidly than neutral •Evaluate the precise degree of constraint on specific positions ...
File
File

... The graphs below show the density of P. expansum spores on normal skin, damaged skin and lenticels (small air pores allowing gaseous exchange) of apples. The experiments show the results at two humidity levels over a four day period. High humidity ...
Small changes, big results: evolution of morphological discontinuity
Small changes, big results: evolution of morphological discontinuity

... and identifying candidate genes responsible for morphological discontinuities in mammals and other organisms. Rather than simple mutations within structural genes, many of the mechanisms underlying change represent more subtle and complex changes involving gene regulation. Complex anatomical differe ...
Variation 2 - Biology Resources
Variation 2 - Biology Resources

... If you worked out the genotypes from the Punnett square, you will realise that the only cattle which will breed true are the ones homozygous for both characteristics BBUU BBuu bbUU bbuu Other crosses are likely to result in some offspring which do not resemble either parent For this reason, all poss ...
How Do Environments Impinge Upon Genes?
How Do Environments Impinge Upon Genes?

... mutations, though all alleles — both those with positive and negative effects —emerge at some point in the evolutionary history of a species through the process of mutation. In this text, we will refer to such mutations as “diseaserelated alleles” or “problematic alleles.”) Researchers know that oth ...
Interpolated Markov Models for Gene Finding
Interpolated Markov Models for Gene Finding

... –  calculate the prob of the ORF sequence in each of the 6 possible reading frames –  if the highest scoring frame corresponds to the reading frame of the ORF, mark the ORF as a gene •  for overlapping ORFs that look like genes –  score overlapping region separately –  predict only one of the ORFs a ...
Document
Document

... Inheritance of biological _____________ is determined by characteristics individual units known as genes ______. During sexual reproduction, genes are offspring passed from parents to _________. Two or more forms of the gene for a trait exist, some forms of the single _____ gene may be _________ dom ...
The Schistosoma gene discovery program: state of the art
The Schistosoma gene discovery program: state of the art

... randomly selected from a library. ESTs can be used for database homology searches against either DNA or protein sequences, in an attempt to identify the genes from which they were derived [20]. The reason behind this approach was because only an insigni®cant fraction of the total genetic information ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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