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... • ImprovedBreakPointReversalSort is an approximation algorithm with a performance guarantee of at most 4 – It eliminates at least one breakpoint in every two steps; at most 2b(p) steps – Approximation ratio: 2b(p) / d(p) – Optimal algorithm eliminates at most 2 breakpoints in every step: d(p)  b(p) ...
Simulating cellular dynamics through a coupled transcription
Simulating cellular dynamics through a coupled transcription

... The dynamics of transcription and translation are accounted for by computing the temporal evolution of the populations of DNA, RNA, proteins and their various complexes within the cell. The model reads and transfers nucleotide and amino acid sequences through a polymerization kinetic model. The rapi ...
AP Biology
AP Biology

... students and scientists alike can compare known and unknown DNA sequences, establish common relationships between organisms, and look for similar protein structures in different organisms. All in a matter of seconds. This lab is an activity introducing you to using this amazing computer program. The ...
comparing quantitative trait loci and gene expression data
comparing quantitative trait loci and gene expression data

... developed in this work is complementary to the analyses that can be performed on the GeneNetwork website (WebQTL, www.genenetwork.org), which allows assessment of the relationship between gene expression and QTLs in Recombinant Inbred mice (Wang et al., 2003). The major advantage of a dual approach ...
VvmybA1 genotype determines grape skin color - Vitis-vea
VvmybA1 genotype determines grape skin color - Vitis-vea

... Introduction: The skin color of grapes is determined by the quantity and composition of anthocyanins. Black and red cultivars accumulate anthocyanins in their skins, whereas white cultivars do not synthesize them. In grape, Myb-related genes such as VlmybA1-1 of Vitis labruscana regulate anthocyanin ...
Answers to test 1
Answers to test 1

... expected single gene ratios (critical values of the chi-square distribution are on the first page of the test paper). Which one of the following is correct? The results are: a) consistent with expected single gene ratios because chi-square = 4.56 b) not consistent with expected single gene ratios be ...
Introduction to Genetics
Introduction to Genetics

... Pink flowers have one normal and one mutant allele; make a smaller amount of red pigment ...
AA - Bryn Mawr School Faculty Web Pages
AA - Bryn Mawr School Faculty Web Pages

... Species A biological species is: a grouping of organisms that can interbreed and are reproductively isolated from other such groups. Species are recognized on the basis of their morphology (size, shape, and appearance) and, more recently, by genetic analysis. For example, there are up to 20 000 spec ...
Genetic instabilities in human cancers
Genetic instabilities in human cancers

... insertions) have been used to study several tumour-cell lines. The mutation rates in such lines have, in general, been found to be roughly equal to those in normal cell lines, with the exception of tumour lines with reported defects in MMR or NER1,18. However, it is dif®cult to compare mutation rate ...
Faster-Z Evolution Is Predominantly Due to Genetic Drift Research
Faster-Z Evolution Is Predominantly Due to Genetic Drift Research

... acting on recessive beneficial mutations (Vicoso and Charlesworth 2009; Mank et al. 2010). By contrast, increased variance in male mating success in birds decreases the effective population size of the Z chromosome (NeZ) below the 3/ 4NeA expected if females and males have equal variance in reproduc ...
Attenuation regulation of amino acid biosynthetic operons in
Attenuation regulation of amino acid biosynthetic operons in

... amino acid (regulatory codons). When transcription proceeds, the antiterminator structure (2:3) folds and prevents terminator formation, resulting in transcription readthrough into downstream genes (Fig. 1B). Under the condition of amino acid excess, the level of charged tRNA is high and translation ...
Microbiology of diabetic foot infections: from Louis Pasteur to Łcrime
Microbiology of diabetic foot infections: from Louis Pasteur to Łcrime

... region of interest. When followed by DNA sequencing, the abundance and genetic composition of a gene of interest can be determined. The small subunit (SSU) ribosomal RNA (rRNA) gene in bacteria, called 16S rRNA, is a useful gene target given that it is conserved across all prokaryotes (bacteria) but ...
B - Zanichelli
B - Zanichelli

Similarities and differences of gene expression in yeast stress
Similarities and differences of gene expression in yeast stress

... similarity measures: number of edges in each graph and a correlation computed for all edges. The tree constructed using the measure of number of edges in the co-co-expression graphs is illustrated in Figure 1. The other measure of correlation for all edges in the graphs was computed as follows. For ...
Risk Factors for Breast Cancer
Risk Factors for Breast Cancer

... Childbirth -- Women who have never had children or who had them only after age 30 have an increased risk of breast cancer. Being pregnant more than once or becoming pregnant at an early age reduces your risk of breast cancer. DES -- Women who took diethylstilbestrol (DES) to prevent miscarriage may ...
User`s guide to GO
User`s guide to GO

...  many of these tools do not support non-model organisms  the tools have different computing requirements  may be difficult to determine how up-to-date the GO annotations are… Need to evaluate tools for your system. ...
Flip Folder 6 KEY - Madison County Schools
Flip Folder 6 KEY - Madison County Schools

... Initiation Complex. (Can you see the definition in the term? Transcription is the process being done. Initiation refers to the beginning process. Complex indicates we have many parts involved in making the structure.) IV. This is a step by step controlled process. (The cell “controls” each step to h ...
PSI Notebook in PDF format
PSI Notebook in PDF format

... 1953. This breakthrough was on a par with Newton's work in physics...but in our recent past. When Watson and Crick published the structure of DNA in a short article in 1953 they stated: "It has not escaped our notice that the specific pairing we have postulated immediately suggests a possible copyin ...
Additional file 1: Figures S1-S9.
Additional file 1: Figures S1-S9.

... (D), 100 μM JA (E) or 100 μM NAA (F) for the time periods indicated. Equal amounts (20 μg) were loaded to each lane and were confirmed by coomassie brilliant blue (CBB) staining of Rubisco (bottom). The experiments were repeated for three times with similar results. Figure S5. Western blot and sout ...
grade: / 125
grade: / 125

... Creutzfeldt-­‐Jakob  and  famililal  fata  insomnia:  get  one  disease  or  the  other   depending  on  which  polymorphism  they  have  at  codon  129  (have  same   mutation  at  codon  128)   Modifier  genes  of  disease  expression, ...
Divergence Pattern of Duplicate Genes in Protein
Divergence Pattern of Duplicate Genes in Protein

... duplicates follow a symmetric or nearly symmetric divergence pattern supports the random interaction turnover model. This model predicts symmetry in the divergence pattern of the duplicates under the assumption of an equal rate of new partner gains for two copies of one duplicate pair as well as a c ...
Article Selection Is No More Efficient in Haploid than in Diploid Life
Article Selection Is No More Efficient in Haploid than in Diploid Life

... would expect haploid-specific genes to evolve more rapidly than diploid-specific or unspecific genes in both species, regardless of the complexity of the phases. To distinguish the factors contributing to evolutionary rate, we generated and compiled genome-wide data on the expression of genes that a ...
Genetics and Genomics -
Genetics and Genomics -

... ($/£ conv. rate 1/1/2003, not PPP-adjusted) ...
Dosage Compensation Mechanisms: Evolution
Dosage Compensation Mechanisms: Evolution

... three cases, the key feature is the existence of a mechanism able to modify transcriptional levels by modulating chromatin structure along whole chromosomes. A consideration of the mechanisms found in protostome species is relevant here. In D. melanogaster, females are the homogametic sex (XX), wher ...
F 1
F 1

... Plasmids can move between the cells during conjugation. They can: • Replicate independently of the main chromosome • Add their genes to the recipient cell’s genome ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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