Lec 18 - Crossing Over
... From these results, it is concluded that the gene cinnabar lies about half – way between the genes for black body colour and vestigial wings. The total amount of crossing over between black body and vestigial wing is 18.5% rather than the 17% expected on the basis of the first cross. The discrepancy ...
... From these results, it is concluded that the gene cinnabar lies about half – way between the genes for black body colour and vestigial wings. The total amount of crossing over between black body and vestigial wing is 18.5% rather than the 17% expected on the basis of the first cross. The discrepancy ...
Chapter 1: The Genetic Approach to Biology Questions for Chapter 1
... Gene - basic elements of the system of inherited information; the fundamental physical and functional unit of heredity, which carries information from one generation to the next; a segment of DNA composed of a transcribed region and a regulatory sequence that makes transcription possible Allele - on ...
... Gene - basic elements of the system of inherited information; the fundamental physical and functional unit of heredity, which carries information from one generation to the next; a segment of DNA composed of a transcribed region and a regulatory sequence that makes transcription possible Allele - on ...
Looping versus linking: toward a model for long
... signal than with the inhibition or exclusion of negative ones. Prior to the commitment to a specific lineage, multipotential hematopoietic progenitor cells initiate gene expression from several different differentiation programs (Hu et al. 1997). Commitment to erythroid differentiation, for example, ...
... signal than with the inhibition or exclusion of negative ones. Prior to the commitment to a specific lineage, multipotential hematopoietic progenitor cells initiate gene expression from several different differentiation programs (Hu et al. 1997). Commitment to erythroid differentiation, for example, ...
Bayesian Networks Classifiers for Gene-Expression Data
... and, second, using a Selective NB. After that, they learn a Bayesian Network using the selected genes. In [26] the same authors also use a Gaussian Selective NB with two improvements: the preordering of the feature set and the application of an irrelevant feature elimination method. As we have said, ...
... and, second, using a Selective NB. After that, they learn a Bayesian Network using the selected genes. In [26] the same authors also use a Gaussian Selective NB with two improvements: the preordering of the feature set and the application of an irrelevant feature elimination method. As we have said, ...
Leukaemia Section t(5;12)(q33;p13) ERC1/PDGFRB Atlas of Genetics and Cytogenetics
... Membrane receptor that binds specifically to PDGFB and has a tyrosine-protein kinase activity. Signal transduction. ...
... Membrane receptor that binds specifically to PDGFB and has a tyrosine-protein kinase activity. Signal transduction. ...
Creating a Venn diagram and list for unique genes from RAST
... Go to rast.nmpdr.org Login to RAST (username: newmanlab password: 16srrna1) In the Jobs Overview window, find the organism you wish to focus on by searching the Name column and click View Details under Annotation Progress In the Job Details window, click Browse annotated genome in the SEED View ...
... Go to rast.nmpdr.org Login to RAST (username: newmanlab password: 16srrna1) In the Jobs Overview window, find the organism you wish to focus on by searching the Name column and click View Details under Annotation Progress In the Job Details window, click Browse annotated genome in the SEED View ...
Gene Section MAP2K4 (mitogen activated protein kinase kinase 4) -
... Genomic studies have identified somatic mutations in the MAP2K4 gene in a total of 11 human cancer tumours (3% of the 356 tumours evaluated). These mutations are located primarily in the kinase domain. The mutations include frameshift, nonsense, and missense mutations and occur in colorectal, nonsma ...
... Genomic studies have identified somatic mutations in the MAP2K4 gene in a total of 11 human cancer tumours (3% of the 356 tumours evaluated). These mutations are located primarily in the kinase domain. The mutations include frameshift, nonsense, and missense mutations and occur in colorectal, nonsma ...
Functions of the nonsense-mediated RNA decay pathway in Drosophila development. PLoS Genetics 2 , 2143-2154.
... relationship between the termination codon and splice junctions in the mRNA [15]. Most normal termination codons are located beyond the last splice junction, in the final exon of the mRNA. Termination codons that lie upstream of an exon–exon boundary are generally recognized as premature and target ...
... relationship between the termination codon and splice junctions in the mRNA [15]. Most normal termination codons are located beyond the last splice junction, in the final exon of the mRNA. Termination codons that lie upstream of an exon–exon boundary are generally recognized as premature and target ...
upstream sequence of a differentiation
... esophageal epithelial cells, but not in mesothelial and kidney epithelial cells or fibroblasts, all of rabbit origin. Serial deletion experiments narrowed this keratinocytespecific promoter to within 300 bp upstream of the transcription initiation site. Its activity is not regulated by the coding or ...
... esophageal epithelial cells, but not in mesothelial and kidney epithelial cells or fibroblasts, all of rabbit origin. Serial deletion experiments narrowed this keratinocytespecific promoter to within 300 bp upstream of the transcription initiation site. Its activity is not regulated by the coding or ...
Nkx5 genes in inner ear development and genome evolution
... Hulander, M., Wurst, W., Carlsson, P., and Enerback, S. (1998) The winged helix transcription factor Fkh10 is required for normal development of the inner ear. Nat. Genet. 20: 374-6 Hughes, A.L. (1999) Phylogenies of developmentally important proteins do not support the hypothesis of two rounds of g ...
... Hulander, M., Wurst, W., Carlsson, P., and Enerback, S. (1998) The winged helix transcription factor Fkh10 is required for normal development of the inner ear. Nat. Genet. 20: 374-6 Hughes, A.L. (1999) Phylogenies of developmentally important proteins do not support the hypothesis of two rounds of g ...
Functional significance of the discordance between
... As recently as 1980, it was widely held that no therapeutic intervention could reverse the dilated cardiomyopathic phenotype of the failing heart once it had developed, thus giving rise to the notion that the development of left ventricular (LV) remodeling and LV dysfunction were irreversible. Howev ...
... As recently as 1980, it was widely held that no therapeutic intervention could reverse the dilated cardiomyopathic phenotype of the failing heart once it had developed, thus giving rise to the notion that the development of left ventricular (LV) remodeling and LV dysfunction were irreversible. Howev ...
Identification of the Minus-Dominance Gene Ortholog in
... agglutination within 1 hr if an aliquot from each was mixed. Such sexually activated, nonmixed cells were used for isolation of gamete RNA. Total RNA was isolated with the RNeasy Midi kit (QIAGEN, Hilden, Germany; protocol for heart, muscle, and skin tissue) after the cells had been homogenized with ...
... agglutination within 1 hr if an aliquot from each was mixed. Such sexually activated, nonmixed cells were used for isolation of gamete RNA. Total RNA was isolated with the RNeasy Midi kit (QIAGEN, Hilden, Germany; protocol for heart, muscle, and skin tissue) after the cells had been homogenized with ...
Chapter 4 DNA, RNA, and the Flow of Genetic Information
... sense of the B-DNA helix. The phosphates in the backbone zigzagged; hence, they called this new form Z-DNA. Section: 4.2 and Figure 4.16 47. What are two features of mature eukaryotic mRNA that are unique as compared to prokaryotic mRNA? Ans: Eukaryotic mRNA has a special nucleotide “cap” at the 5' ...
... sense of the B-DNA helix. The phosphates in the backbone zigzagged; hence, they called this new form Z-DNA. Section: 4.2 and Figure 4.16 47. What are two features of mature eukaryotic mRNA that are unique as compared to prokaryotic mRNA? Ans: Eukaryotic mRNA has a special nucleotide “cap” at the 5' ...
Bez nadpisu - Univerzita Karlova v Praze
... type of C1 INH mutation associated rather with laboratory phenotype than clinical manifestation • missense mutation in the reactive center loop - 75% patients with HAE type II • large deletions, nonsense, frameshift and splicing mutations – causal usually in HAE type I • inframe del/ins, missense ...
... type of C1 INH mutation associated rather with laboratory phenotype than clinical manifestation • missense mutation in the reactive center loop - 75% patients with HAE type II • large deletions, nonsense, frameshift and splicing mutations – causal usually in HAE type I • inframe del/ins, missense ...
AP Inheritance
... used experimental method used quantitative analysis collected data & counted them ...
... used experimental method used quantitative analysis collected data & counted them ...
PDF - Blood Journal
... RNA from peripheral blood and used this to construct a cDNA library. This library was screened under low-stringency conditions with salmon ␣- and -globin cDNA probes.15 Twenty-four positive clones were picked and were analyzed by restriction mapping followed by sequencing and database searches. Thi ...
... RNA from peripheral blood and used this to construct a cDNA library. This library was screened under low-stringency conditions with salmon ␣- and -globin cDNA probes.15 Twenty-four positive clones were picked and were analyzed by restriction mapping followed by sequencing and database searches. Thi ...
teacher version
... of long sequences of DNA that provide the information needed to construct an organism. If you were to line up the DNA from just one of your cells end-to-end, it would be over 7 feet long. That’s about 80 billion miles of DNA from all the cells in an average adult human! A human genome can be divided ...
... of long sequences of DNA that provide the information needed to construct an organism. If you were to line up the DNA from just one of your cells end-to-end, it would be over 7 feet long. That’s about 80 billion miles of DNA from all the cells in an average adult human! A human genome can be divided ...
Disruption of an N-acetyltransferase gene in the
... the BmMDB database (Xia et al., 2007) and temporal profiles (available from GEO with accession GSE24611) were determined by the Agilent 8X15K gene expression platform. Insects were sampled daily in the larval and pupal stages. Total RNA of each sample was extracted separately and then mixed equally ...
... the BmMDB database (Xia et al., 2007) and temporal profiles (available from GEO with accession GSE24611) were determined by the Agilent 8X15K gene expression platform. Insects were sampled daily in the larval and pupal stages. Total RNA of each sample was extracted separately and then mixed equally ...
Data Mining in GEO and Beyond
... All GEO submissions need to be associated with a platform file. These describe the features on a given platform, required to understand the data. A platform file must be submitted if one is not already present in GEO. Commercial array platform files are submitted to GEO by the manufacturer. ...
... All GEO submissions need to be associated with a platform file. These describe the features on a given platform, required to understand the data. A platform file must be submitted if one is not already present in GEO. Commercial array platform files are submitted to GEO by the manufacturer. ...
Lecture 6: May 31, 2007 6.1 Introduction to Classification 6.2
... construction is PCA - Principal Component Analysis [3], an analytical method which finds a linear transformation that chooses a new coordinate system for the data set. In the new coordinates, the greatest variance by any projection of the data set comes to lie on the first axis (termed the first pri ...
... construction is PCA - Principal Component Analysis [3], an analytical method which finds a linear transformation that chooses a new coordinate system for the data set. In the new coordinates, the greatest variance by any projection of the data set comes to lie on the first axis (termed the first pri ...
Life Science Knowledge Collider
... • A platform offering software infrastructure for: – automatic semantic annotation of text ...
... • A platform offering software infrastructure for: – automatic semantic annotation of text ...
Gene Section ADIPOR1 (adiponectin receptor 1) Atlas of Genetics and Cytogenetics
... peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine. We have also shown expression in normal and cancerous breast tissue as well as in other cancers such as prostate, colon, endometrial. It is also present in several cell lines. ...
... peripheral blood leukocytes. Weakly expressed in colon, thymus and small intestine. We have also shown expression in normal and cancerous breast tissue as well as in other cancers such as prostate, colon, endometrial. It is also present in several cell lines. ...
Mutations - GK-12 Program at the University of Houston
... NGSS, Life Sciences, High School (6-8), HS-LS3-2, Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors. Pre-Req ...
... NGSS, Life Sciences, High School (6-8), HS-LS3-2, Make and defend a claim based on evidence that inheritable genetic variations may result from: (1) new genetic combinations through meiosis, (2) viable errors occurring during replication, and/or (3) mutations caused by environmental factors. Pre-Req ...
Package `GOFunction`
... folder. This table contains seven columns: goid, name, refnum (the number of the reference genes in a GO term), interestnum (the number of the interesting genes in a GO term), pvalue, adjustp (the corrected p value by the fdr control), FinalResults. The "FinalResults" contains three types: (1) "Loca ...
... folder. This table contains seven columns: goid, name, refnum (the number of the reference genes in a GO term), interestnum (the number of the interesting genes in a GO term), pvalue, adjustp (the corrected p value by the fdr control), FinalResults. The "FinalResults" contains three types: (1) "Loca ...
Potential relationship between genotype and clinical
... 37 Spanish PA patients in relation to the mutations found in both PCCA and PCCB genes. We have detected 27 early-onset and 10 late-onset cases, showing remarkably similar biochemical features without relation to either the age of onset of the disease or the defective gene they have. Twenty-one of th ...
... 37 Spanish PA patients in relation to the mutations found in both PCCA and PCCB genes. We have detected 27 early-onset and 10 late-onset cases, showing remarkably similar biochemical features without relation to either the age of onset of the disease or the defective gene they have. Twenty-one of th ...
RNA-Seq
RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.