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lecture 3 notes
lecture 3 notes

... Ciliates are diploid and have one micro diploid nucleus that only participates during sexual reproduction (no transcription). Genes in the micronucleus in some species are completely scrambled. During macronucleus formation, sequences and orientation of the genes is restored. Macronuclei contain num ...
Slides - nanoHUB
Slides - nanoHUB

... 2. Difference between major & minor groove -- see today’s viewgraphs 3. Why is one end of DNA called 5’? The other 3’? -- the nomenclature of sugar #’s. (today) 4. More about DNA folding – why a meter long can compact into a few microns -- have a special section on DNA bending and twisting with magn ...
Efficient gusA Transient Expression in Porphyra yezoensis
Efficient gusA Transient Expression in Porphyra yezoensis

... 1) College of Medicine and Pharmaceutics, Ocean University of China, Qingdao 266003, P. R. China 2) College of Marine Life Sciences, Ocean University of China, Qingdao 266003, P. R. China 3) College of Fisheries, Ocean University of China, Qingdao 266003, P. R. China (Received April 25, 2006; accept ...
Class 26 - Columbia University
Class 26 - Columbia University

... This enrichment procedure is just the SELEX method described earlier for finding the RNA substrate for RNA binding proteins. In this case it’s the same procedure, looked from the opposite point of view: not what RNA will the protein bind best, but what RNA binds the protein best. ...
Chapter 11
Chapter 11

... F2 – second filial generation 1) Traits passed from P to F1 through chemical factors (genes). Traits are found in contrasting forms. The alternative (different) forms of a gene are called alleles. 2) The principle of dominance states that some alleles are dominant and others are recessive. Dominant ...
Molecular Biology
Molecular Biology

... DNA stores information and proteins form the basic structures and perform the basic functions of life systems. The biological functions of DNA, RNA and protein molecules are mostly encoded in the linear sequence of their basic units. Analysis of the unit sequences of DNA, RNA or proteins can reveal ...
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... contain mobility genes (i.e. transposases, integrases), and are associated with tRNA sequences. Combined identification of such features could facilitate the identification of genes in new genomes sequences that are involved in virulence, or have horizontal origins. ...
Appendix Genomic
Appendix Genomic

... It comes in the form of a linear threadlike DNA strand bound to diverse proteins in the nucleus of eukaryotic cells, or a circular DNA strand (or RNA strand in the case of some viruses) found in the cytoplasm of prokaryotic cells and in the mitochondria and chloroplasts of certain eukaryotic cells. ...
VCE BIOLOGY 2013–2016 Introduction
VCE BIOLOGY 2013–2016 Introduction

... DNA stores information and proteins form the basic structures and perform the basic functions of life systems. The biological functions of DNA, RNA and protein molecules are mostly encoded in the linear sequence of their basic units. Analysis of the unit sequences of DNA, RNA or proteins can reveal ...
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... approaches to construct a robust set of motifs active in the yeast genome. With this set we consider the combinatorial actions of these motifs and apply a linear model to explain observed expression. A deeper understanding of gene regulation in yeast is the first step toward understanding gene regul ...
Cancer Prone Disease Section Trichothiodystrophy (TTD) Atlas of Genetics and Cytogenetics
Cancer Prone Disease Section Trichothiodystrophy (TTD) Atlas of Genetics and Cytogenetics

... The DNA repair defect is found in 3 classes: Patient with TTD-A group (low level of the TFIIH transcription factor), Patients mutated in the XPB gene (TTD/XPB), involving XPB, also called ERCC3, located in 2q21; and All the other patients mutated in the XPD gene (TTD/XPD), involving XPD, also called ...
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Assigned exercise

... PubMed tutorial: http://www.nlm.nih.gov/bsd/disted/pubmedtutorial/020_010.html The tutorial consists of several dozen pages online, but they are relatively short and easy to understand. Pay particular attention to the sections on navigating PubMed’s home page, using fields to narrow down a search, a ...
Computational Biology 15
Computational Biology 15

... linked chromosomal region is essential for obtaining new information about a disease or biological process. The process of identifying genetic loci within linked chromosomal regions is difficult and often unproductive, which has been a source of frustration for many (50). However, the following thre ...
PHYS 498 Quiz 1 Solution Starting with double
PHYS 498 Quiz 1 Solution Starting with double

... Energetics of formation of RNA and protein RNA is formed through covalent bond between nucleotides. The formation of the phosphodiester bond in RNA requires energy, and this energy is derived from the nucleoside triphosphates (NTPs). Other than the energy needed for polymerization, there is also an ...
Chapter 11.5
Chapter 11.5

... Human gene linkages were identified by tracking phenotypes in families over generations ◦ Crossovers are not rare and in some cases one crossover must occur between each chromosome before meiosis can be properly completed ...
“Ancient” Viruses
“Ancient” Viruses

... Some terminology from the last part of ...
Guided Exploration- (RI3) Learning Goal Three: Explain how DNA is
Guided Exploration- (RI3) Learning Goal Three: Explain how DNA is

... The workers have assistants fetch the correct supplies in the kingdom. Then they read the instructions, and put the supplies together just like the instructions said. When the workers were finished, they had a beautiful castle before them and were happy that they had done such a good job. DNA, Trans ...
GENETICS The Future of Medicine
GENETICS The Future of Medicine

... phenylketonuria (PKU), a metabolic disorder that prevents the breakdown of phenylalanine, one of the building blocks of proteins and a component of the artificial sweetener Aspartame. Excess phenylalanine in the body is toxic to the nervous system. In the past, children with the condition became sev ...
DNA Quiz #1 - Houston ISD
DNA Quiz #1 - Houston ISD

... 12. ____________ is complementary to the original DNA strand? 13. The mRNA carries information from the nucleus to a _________. 14. What is the correct base pairing of RNA? ___=___ ___=___ 15. Translation takes place in the ________________. 16. Replication, transcription, and translation are the st ...
7th Grade Science Notes
7th Grade Science Notes

... Some traits are controlled by more than one gene. Each gene can have many alleles that interact with the other genes to produce a large number of phenotypes. An example of this type of trait is skin color, eye color, and height. ...
GMO and Biotechnology
GMO and Biotechnology

... • single genes/traits can be transferred, • species boundaries are not limiting. ...
G - AP Bio Take 5
G - AP Bio Take 5

... primary transcript = This is pre-mRNA  When mRNA is spliced….the INTRONS are edited out!  make mature (final) mRNA transcript ...
Imprinted green beards: a little less than kin and more than kind
Imprinted green beards: a little less than kin and more than kind

... Figure 1. The mesiRNA ratchet. A population initially fixed for allele A (upper left) is successively invaded by an allele A 0 that also encodes a mesiRNA; an allele A8 that retains the mesiRNA but is insensitive to its effects and an allele A* that encodes a new mesiRNA (lower right). Subscripts m ...
Regulation of Gene Transcription
Regulation of Gene Transcription

... Basics and Logic of prokaryotic transcription regulation: A great example of regulation of gene transcription comes from prokaryotes and their regulation of metabolic enzymes to break down sugars (lactose, glucose, etc.) if all enzymes where transcribed it would be too energetically costly Therefore ...
Gene Section NUP98 (nucleoporin 98 kDa) Atlas of Genetics and Cytogenetics
Gene Section NUP98 (nucleoporin 98 kDa) Atlas of Genetics and Cytogenetics

... This article is an update of: Huret JL. NUP98 (nucleoporin 98 kDa). Atlas Genet Cytogenet Oncol Haematol.1998;2(1):7. This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. © 1999 Atlas of Genetics and Cytogenetics in Oncology and Haematology ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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