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Profile Documents Logout
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MS Word file
MS Word file

... Regulatory promoter A variety of different consensus sequences may be found in the regulatory promoters. Main difference between prokaryotes and eukaryotes is in assembly of ...
Biocept to Present at the 103rd AACR Annual Meeting
Biocept to Present at the 103rd AACR Annual Meeting

... San Diego, California – Biocept, Inc., a privately-held, CLIA certified laboratory testing company focused on detection and analysis of circulating tumor cells (CTCs) in cancer patients, announced that it will be presenting three posters at the 103nd Annual Meeting of the American Association for Ca ...
Gene therapy- Methods, Status and Limitations
Gene therapy- Methods, Status and Limitations

... • Viruses attack their hosts and introduce their genetic material containing genetic material into the host cell as part of their replication cycle. ...
transcription and translation
transcription and translation

... Involves ribosome, mRNA and tRNA (transfer RNA) Ribosome reads mRNA on codon (3 bases) at a time tRNA matches with codon on mRNA Brings amino acid with ...
Lecture #21 - Faculty Web Sites at the University of Virginia
Lecture #21 - Faculty Web Sites at the University of Virginia

... No proofreading capacity therefore vast majority of Proviral DNAs are nonfunctional owing to mutations But this also explains how drug-resistant HIV strains emerge rapidly Therefore, virus production requires a given cell to be simultaneously infected by numerous viruses so mutants can complement ea ...
DNA→ RNA
DNA→ RNA

... If the diameter of the DNA (2 nanometers) was as wide as a fishing line (0.5 millimeters) it might stretch as far as 21.2 km (or 13.6 miles) in length which would all have to be packed into a nucleus, the equivalent size of 25 cm in ...
Transcription
Transcription

... 5SrRNA promoter split into 3 parts tRNA promoters split into two parts ...
Colorectal cancer (CRC) remains one of the most frequently
Colorectal cancer (CRC) remains one of the most frequently

... defective mismatch repair (MMR) system, which is caused by mutations in one of MMR genes such as hMLH1 and hMSH2, epigenetic silencing of the hMLH1 gene, and oxidative inactivation of the MMR function. MSI has been detected in ~90% hereditary and ~15% of sporadic CRC, and CRC accounts for ~15% of al ...
Heredity Passing It On pp1 and 2
Heredity Passing It On pp1 and 2

... to replace old or dying cells throughout our bodies. These cells need to be exactly like their parent cells so they are able to continue doing their jobs. If offspring were produced through mitosis, as they often are in single-celled organisms, each offspring would be identical to its parent. In sex ...
PPT# 4 Notes: Mutations and Regulation     ...  Date______________Per._______
PPT# 4 Notes: Mutations and Regulation ... Date______________Per._______

Chapters 25-26 V2
Chapters 25-26 V2

... is DNA the primary genetic material today?? ...
Final Exam Genetics Fall 2011
Final Exam Genetics Fall 2011

... 35) In humans, the genetic basis for determining the sex "male" is accomplished by the presence of ________. A) one X chromosome B) a balance between the number of X chromosomes and the number of haploid sets of autosomes C) a portion of the Y chromosome D) high levels of estrogen E) multiple allele ...
Evolution notes lecture Genetic Variation and Gene Regulation Fall
Evolution notes lecture Genetic Variation and Gene Regulation Fall

...  Contains a series of genes, e.g., lac operon.  Genes have regulation sites—signal areas for beginning transcription, stopping.  Genes include introns and exons  Exons (expressed sequences) are coding regions for transcription of m-RNA and translation into proteins  Introns are non-coding regio ...
Replication Transcription Translation
Replication Transcription Translation

... two identical DNA molecules form ...
Genes
Genes

...  synthesizing end products ...
9.
9.

... homology and therefore have similar distributions of constrained sites. The most likely origin of structural homology between interacting proteins is duplication of the gene that encodes a homodimeric protein, followed by evolution of one copy of the gene. This process would result in homology not o ...
Advanced Molecular and Cell Biology (Dorn, Holton)
Advanced Molecular and Cell Biology (Dorn, Holton)

... the most rapidly advancing and fascinating fields of genetics research today. In large part that rapid advance is the direct result of the technological advances that have become possible in the “post-genomics” era, like surveying the expression of every single gene in an organism’s genome (20,000 h ...
Chapters 10 and 11 - Cellular Reproduction, Meiosis and Genetics
Chapters 10 and 11 - Cellular Reproduction, Meiosis and Genetics

... 5. When you flip a coin, what is the probability that it will come up tails? ½ What is the probability that it will come up heads three times in a row? ½ x ½ x ½ = 1/8 6. Organisms that have two identical alleles for a particular trait are said to be homozygous 7. Situations in which one allele for ...
ppt - Barley World
ppt - Barley World

... • Micro projectile bombardment or the biolistic method • Small metal particles are coated with the transgene DNA • Particles are delivered to target tissues via an explosive force ...
Zebrafish Jeopardy
Zebrafish Jeopardy

... the type of replication that would occur if all of the second generation DNA molecules consisted of 75% radioactive DNA and 25% parental DNA. What is dispersive replication? Home ...
Gene Regulation
Gene Regulation

... – Transcription and translation are expensive • Each nucleotide = 2 ATP in transcription • Several GTP/ATP per amino acid in translation • If protein is not needed, don’t waste energy! – Changes in food availability, environmental conditions lead to differential gene expression • Degradation genes t ...
32_operons2
32_operons2

... Galactose is yet another sugar that E. coli can metabolize. • Will those genes be repressible or inducible? • How might gal be regulated? CAP O ...
BIO 132: Genes and People
BIO 132: Genes and People

... Exam 3: Problems DNA sequences will be provided and students will have to illustrate the protein product from the sequence Short answer question on chromosome segregation to illustrate normal and abnormal ...
Epigenetics
Epigenetics

... X:autosome translocation • In this case, X-inactivation is not random - the normal X is always inactivated, because the translocation interferes with the inactivation process • Therefore, the normal DMD gene is switched off, and the other one is disrupted by the translocation • So these girls show t ...
Snímek 1
Snímek 1

... protein. Depletion of MBNL1 proteins results in inclusion of additional exons (e.g., exon 7a) containing premature termination codons. Aberrantly spliced CLCN1 transcripts are exported from the nucleus, degraded through the nonsense-mediated decay pathway, and/or produce truncated proteins. These ef ...
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RNA-Seq



RNA-seq (RNA sequencing), also called whole transcriptome shotgun sequencing (WTSS), is a technology that uses the capabilities of next-generation sequencing to reveal a snapshot of RNA presence and quantity from a genome at a given moment in time.
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