
Lecture 7 Citric acid cycle
... acids, glucose, and some amino acids yields acetylCoA. Stage 2: oxidation of acetyl groups in the citric acid cycle includes four steps in which electrons are abstracted. ...
... acids, glucose, and some amino acids yields acetylCoA. Stage 2: oxidation of acetyl groups in the citric acid cycle includes four steps in which electrons are abstracted. ...
Hein and Arena
... 1. Incorporated into a protein 2. Used to synthesize other nitrogenous compounds such as nucleic acids, or 3. Deaminated to a keto acid, which can either be used to synthesize other compounds or be oxidized to carbon dioxide and water to provide energy. ...
... 1. Incorporated into a protein 2. Used to synthesize other nitrogenous compounds such as nucleic acids, or 3. Deaminated to a keto acid, which can either be used to synthesize other compounds or be oxidized to carbon dioxide and water to provide energy. ...
info and study guide
... Compartmentalization of pathways Know regulatory steps; understand why regulatory scheme makes sense in big picture Determine free energy changes of reactions qualitatively and quantitatively Physiology/pathology from slides Exam Format: The exam is out of 100 points. The first 60 points wil ...
... Compartmentalization of pathways Know regulatory steps; understand why regulatory scheme makes sense in big picture Determine free energy changes of reactions qualitatively and quantitatively Physiology/pathology from slides Exam Format: The exam is out of 100 points. The first 60 points wil ...
Nutritional management in chronic kidney diseases and
... ESPEN, European Society for Clinical Nutrition and Metabolism; NKF, National Kidney Foundation; EAA, essential amino acids; GFR, glomerular filtration rate; HBV, ...
... ESPEN, European Society for Clinical Nutrition and Metabolism; NKF, National Kidney Foundation; EAA, essential amino acids; GFR, glomerular filtration rate; HBV, ...
BCHM 463 Supplemental Problems for Friday, April 9, 2004 1. a
... b) Rationalize the use of these enzymes as control points (i.e. Why are these enzymes able to serve as control points?)? These enzymes function far from equilibrium (i.e. have large negative ∆G) and can therefore serve as control points for flux through this pathway. ...
... b) Rationalize the use of these enzymes as control points (i.e. Why are these enzymes able to serve as control points?)? These enzymes function far from equilibrium (i.e. have large negative ∆G) and can therefore serve as control points for flux through this pathway. ...
Bioenergetics and Metabolism
... reactants and products. The names describe the metabolite structures, draw them if you like, or visualize them in your head. ...
... reactants and products. The names describe the metabolite structures, draw them if you like, or visualize them in your head. ...
01_Introduction. Structure, properties and biological functions
... PLP is a coenzyme for enzymes catalyzing reactions involving amino acid metabolism (isomerizations, decarboxylations, transamination) ...
... PLP is a coenzyme for enzymes catalyzing reactions involving amino acid metabolism (isomerizations, decarboxylations, transamination) ...
Enzymes - WordPress.com
... The active site of an enzyme binds the substrate molecule(s) of a biochemical reaction, and is critical to its specificity and catalytic activity. Many enzymes are specific for just one reaction. For example, catalase only catalyzes the breakdown of hydrogen peroxide, a toxic by-product of metabolis ...
... The active site of an enzyme binds the substrate molecule(s) of a biochemical reaction, and is critical to its specificity and catalytic activity. Many enzymes are specific for just one reaction. For example, catalase only catalyzes the breakdown of hydrogen peroxide, a toxic by-product of metabolis ...
Chemistry of Natural Compounds
... ORGANIC AND BIOMOLECULAR CHEMISTRY - Vol. I - Chemistry of Natural Compounds - L. Cipolla ...
... ORGANIC AND BIOMOLECULAR CHEMISTRY - Vol. I - Chemistry of Natural Compounds - L. Cipolla ...
6_Petrin_prot_DBs_2011
... • Some include all the available information (more or less reliable information) – large coverage, everything is stored in the database – small reliablity, information has not been confirmed – computer annotation => updating fast ...
... • Some include all the available information (more or less reliable information) – large coverage, everything is stored in the database – small reliablity, information has not been confirmed – computer annotation => updating fast ...
BIOTRANSFORMATION
... suitable functional groups as COOH,-OH,-NH2,- SH. • Thus is called as Conjugation reactions. • Since the product formed is having high molecular weight so called as synthetic reactions. • The product formed is hydrophilic in nature with total loss of pharmacologic activity so called as a true detoxi ...
... suitable functional groups as COOH,-OH,-NH2,- SH. • Thus is called as Conjugation reactions. • Since the product formed is having high molecular weight so called as synthetic reactions. • The product formed is hydrophilic in nature with total loss of pharmacologic activity so called as a true detoxi ...
The Affect of Enzymes on a Chemical Reaction
... repeated these steps with the other Dixie cups labeled with a specific time on them. When doing the 0 sec Dixie cup I did not add any catalase, but I did add the 10mL of sulfuric acid (this solution will be used to find the base line). In order to find the base line I filled my burette with potassiu ...
... repeated these steps with the other Dixie cups labeled with a specific time on them. When doing the 0 sec Dixie cup I did not add any catalase, but I did add the 10mL of sulfuric acid (this solution will be used to find the base line). In order to find the base line I filled my burette with potassiu ...
Inborn errors of metabolism
... mothers with PKU during pregnancy: the importance of variation in maternal blood Phe • Methods: 67 mothers PKU/105 children at ages 1, 4, 8, and 14, and the times of starting a Phe-restricted diet, either before or after conception.. • Results: -women with PKU should start a Phe-restricted diet befo ...
... mothers with PKU during pregnancy: the importance of variation in maternal blood Phe • Methods: 67 mothers PKU/105 children at ages 1, 4, 8, and 14, and the times of starting a Phe-restricted diet, either before or after conception.. • Results: -women with PKU should start a Phe-restricted diet befo ...
The Citric acid cycle
... acetate succinate, malate, a-ketoglutaric acid (dicarboxylic acids) and citrate and isocitrate (tricarboxylic acids) when added to muscle mince that they stimulated oxygen consumption and release of CO2 1935Albert Szent-Gyorgyi showed that ...
... acetate succinate, malate, a-ketoglutaric acid (dicarboxylic acids) and citrate and isocitrate (tricarboxylic acids) when added to muscle mince that they stimulated oxygen consumption and release of CO2 1935Albert Szent-Gyorgyi showed that ...
Enzymes Review Game with Answers 2014 2015
... There are many different enzymes located in a single cell. Why do enzymes catalyze a specific reaction? A. B. ...
... There are many different enzymes located in a single cell. Why do enzymes catalyze a specific reaction? A. B. ...
Aminoaciduria
... Inborn Errors of Amino Acid Metabolism 3- Disorders of tyrosine amino acid metabolism Disorders of tyrosine amino acid metabolism lead to the following consequences: 1- Deficiency of melanin pigments (Albinism) Tyrosine is the precursor of melanin (by tyrosinase enzyme) Deficiency of tyrosine leads ...
... Inborn Errors of Amino Acid Metabolism 3- Disorders of tyrosine amino acid metabolism Disorders of tyrosine amino acid metabolism lead to the following consequences: 1- Deficiency of melanin pigments (Albinism) Tyrosine is the precursor of melanin (by tyrosinase enzyme) Deficiency of tyrosine leads ...
factors_effecting_en..
... fastest. For most enzymes this is about pH 7-8 (physiological pH of most cells), but a few enzymes can work at extreme pH, such as protease enzymes in animal stomachs, which have an optimum of pH 1 The pH affects the charge of the amino acids at the active site, so the properties of the active site ...
... fastest. For most enzymes this is about pH 7-8 (physiological pH of most cells), but a few enzymes can work at extreme pH, such as protease enzymes in animal stomachs, which have an optimum of pH 1 The pH affects the charge of the amino acids at the active site, so the properties of the active site ...
FR-7.02 Allergy Injections in College Health Setting
... Administer epinephrine ASAP! There is no contraindication Fatalities usually result from delayed administration of epinephrine--with respiratory, and cardiovascular complications Subsequent care based on response to epinephrine ...
... Administer epinephrine ASAP! There is no contraindication Fatalities usually result from delayed administration of epinephrine--with respiratory, and cardiovascular complications Subsequent care based on response to epinephrine ...
Cortisone is an injectable anti-inflammatory medication that has
... and/or to use crutches, rolling walkers or wheel chairs to allow the swelling to recede (i.e. swelling leads to pain). Oral steroids and/or non-steroidal anti-inflamatories do not work as well and are usually used in combination with injectable steroids. Cortisone is a hormone secreted by the adrena ...
... and/or to use crutches, rolling walkers or wheel chairs to allow the swelling to recede (i.e. swelling leads to pain). Oral steroids and/or non-steroidal anti-inflamatories do not work as well and are usually used in combination with injectable steroids. Cortisone is a hormone secreted by the adrena ...
Chem 150 quiz #6
... e. none of the above 18. How many molecules of pyruvate would be obtained if 3 molecules of glucose are degraded to pyruvate in Glycolysis? a. 3 b. 4 c. 6 d. 8 e. 12 19. Which reaction in glycolysis involves the breaking of a C-C bond? a. step 10 b. step 2 c. step 5 d. step 9 e. none of the above 20 ...
... e. none of the above 18. How many molecules of pyruvate would be obtained if 3 molecules of glucose are degraded to pyruvate in Glycolysis? a. 3 b. 4 c. 6 d. 8 e. 12 19. Which reaction in glycolysis involves the breaking of a C-C bond? a. step 10 b. step 2 c. step 5 d. step 9 e. none of the above 20 ...
References - The University of New Mexico
... Key Words: Lactate, Metabolism, Dissociation Constants ...
... Key Words: Lactate, Metabolism, Dissociation Constants ...
Metabolic network modelling

Metabolic network reconstruction and simulation allows for an in-depth insight into the molecular mechanisms of a particular organism. In particular, these models correlate the genome with molecular physiology. A reconstruction breaks down metabolic pathways (such as glycolysis and the Citric acid cycle) into their respective reactions and enzymes, and analyzes them within the perspective of the entire network. In simplified terms, a reconstruction collects all of the relevant metabolic information of an organism and compiles it in a mathematical model. Validation and analysis of reconstructions can allow identification of key features of metabolism such as growth yield, resource distribution, network robustness, and gene essentiality. This knowledge can then be applied to create novel biotechnology.In general, the process to build a reconstruction is as follows: Draft a reconstruction Refine the model Convert model into a mathematical/computational representation Evaluate and debug model through experimentation↑