What is an Autoimmune Disease?
... Self and non-self A healthy immune system is able to tell the difference between your cells – “self”, from an invader's cells – “non-self”. Both have markers, distinguishing them as self and non-self. When a healthy immune system recognizes the non-self markers, it launches an attack on them in an ...
... Self and non-self A healthy immune system is able to tell the difference between your cells – “self”, from an invader's cells – “non-self”. Both have markers, distinguishing them as self and non-self. When a healthy immune system recognizes the non-self markers, it launches an attack on them in an ...
HO-notecards
... 3. myelocyte—nucleus may be eccentric, cytoplasm may have pink granules 4. metamyelocytes—kidney bean shaped nucleus 5. band—horseshoe shaped nucleus 6. PMN—lobular nucleus --first line of defense for microorganisms, chemotatic, opsonins, lysosomal enzymes KNOW: hydrogen peroxide, superoxide, halide ...
... 3. myelocyte—nucleus may be eccentric, cytoplasm may have pink granules 4. metamyelocytes—kidney bean shaped nucleus 5. band—horseshoe shaped nucleus 6. PMN—lobular nucleus --first line of defense for microorganisms, chemotatic, opsonins, lysosomal enzymes KNOW: hydrogen peroxide, superoxide, halide ...
Biol 155 Human Physiology - Department of Zoology, UBC
... Ability to resist damage from foreign substances as microorganisms and harmful chemicals Categories ...
... Ability to resist damage from foreign substances as microorganisms and harmful chemicals Categories ...
Newborn Screening for Severe Combined
... the disorder is present at birth. Typically SCID includes problems with both T cell and B cell function, which can result in the onset of one or more serious infections in the first few months of life. T cells originate in the bone marrow, mature in the thymus gland, and then enter into the blood str ...
... the disorder is present at birth. Typically SCID includes problems with both T cell and B cell function, which can result in the onset of one or more serious infections in the first few months of life. T cells originate in the bone marrow, mature in the thymus gland, and then enter into the blood str ...
X-linked hyper IgM syndrome = CD40 ligand deficiency
... Nude (nu/nu) mice : •Hairless mouse spontaneously generated in a mouse facility •Athymic or vestigial thymus, so very few T cells. •In both mice and humans, mutations in FOXN1 (also known as WHN), transcription factor selectively expressed in skin and thymus •FOXN1 is necessary for the differentiati ...
... Nude (nu/nu) mice : •Hairless mouse spontaneously generated in a mouse facility •Athymic or vestigial thymus, so very few T cells. •In both mice and humans, mutations in FOXN1 (also known as WHN), transcription factor selectively expressed in skin and thymus •FOXN1 is necessary for the differentiati ...
Chapter 12
... ○ IFN-γ was studied because of it’s ability to block viral replication like other interferons - However, this IFN plays immunoregulatory role which lead to understanding the process of signal transduction through cytokine receptors - Look on next slide ...
... ○ IFN-γ was studied because of it’s ability to block viral replication like other interferons - However, this IFN plays immunoregulatory role which lead to understanding the process of signal transduction through cytokine receptors - Look on next slide ...
Defence Against Disease
... • The immunoglobulins of each B-cell have a specific structure and recognise only one kind of antigen. • There are millions of antigens that the body must be able to respond. In response to this millions of different B-cells are produced with different immunoglobulins on their surfaces. • Self – tol ...
... • The immunoglobulins of each B-cell have a specific structure and recognise only one kind of antigen. • There are millions of antigens that the body must be able to respond. In response to this millions of different B-cells are produced with different immunoglobulins on their surfaces. • Self – tol ...
021309.M1-Immuno.Cytokines - Open.Michigan
... and Immunology License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution–Noncommercial–Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have t ...
... and Immunology License: Unless otherwise noted, this material is made available under the terms of the Creative Commons Attribution–Noncommercial–Share Alike 3.0 License: http://creativecommons.org/licenses/by-nc-sa/3.0/ We have reviewed this material in accordance with U.S. Copyright Law and have t ...
Hypersensitivity-contact dermatitis
... •They also reduce risk of death if immune system is unsuccessful. ...
... •They also reduce risk of death if immune system is unsuccessful. ...
Microbiology
... medium. Stem cell lines and groups of stem cells form colonies in culture medium. Different conditions, as well as growth factors added to culture medium, direct stem cells to become stem cell lines for various tissues of the body (e.g., blood and lymphatic cells, pancreatic islet cells, nerve cells ...
... medium. Stem cell lines and groups of stem cells form colonies in culture medium. Different conditions, as well as growth factors added to culture medium, direct stem cells to become stem cell lines for various tissues of the body (e.g., blood and lymphatic cells, pancreatic islet cells, nerve cells ...
Antibody
... foreign materials, neutralizes and removes them • one basis of immunity is the recognition of a foreign material, the antigen, by a glycoprotein molecule in the body, the antibody. • antibodies that recognize “self” occur in the body, but they are removed and destroyed immediately after synthesis. • ...
... foreign materials, neutralizes and removes them • one basis of immunity is the recognition of a foreign material, the antigen, by a glycoprotein molecule in the body, the antibody. • antibodies that recognize “self” occur in the body, but they are removed and destroyed immediately after synthesis. • ...
Lecture 17 - Mechanisms of Pathogenecity Chpt. 17
... •Production of toxins that are then ingested •Colonization of surface of the host, followed by toxin production •Invasion of host tissues •Invasion of host tissues followed by toxin production ...
... •Production of toxins that are then ingested •Colonization of surface of the host, followed by toxin production •Invasion of host tissues •Invasion of host tissues followed by toxin production ...
Powerpoint
... Helper t-cells (CD4 cells) – get information of invasions and report to spleen and lymph nodes to stimulate lymphocytes for attack. Suppressor t-cells – slow down or stop immune processes. ...
... Helper t-cells (CD4 cells) – get information of invasions and report to spleen and lymph nodes to stimulate lymphocytes for attack. Suppressor t-cells – slow down or stop immune processes. ...
Notes-Blood and Immunity
... macrophages are types of white blood cells. Lymphocytes: recognize antigens and then destroy pathogens. They are produced in the bone marrow. If they mature within the bone marrow, they are called B cells. Some lymphocytes migrate to the thymus gland and then mature. These lymphocytes are called T c ...
... macrophages are types of white blood cells. Lymphocytes: recognize antigens and then destroy pathogens. They are produced in the bone marrow. If they mature within the bone marrow, they are called B cells. Some lymphocytes migrate to the thymus gland and then mature. These lymphocytes are called T c ...
Section 18 Immunity in the Fetus and Newborn
... • The precise schedule will depend on the vaccine used and the species to be vaccinated. ...
... • The precise schedule will depend on the vaccine used and the species to be vaccinated. ...
HP_Tipaje Linfocitario_24 07 13
... The immune system consists of a series of organs, tissues and cells widely distributed throughout the entire body. These components are interconnected by blood and lymph vessels, constituting a single well-communicated system. The response mechanisms of the immune system are the innate or non-adapti ...
... The immune system consists of a series of organs, tissues and cells widely distributed throughout the entire body. These components are interconnected by blood and lymph vessels, constituting a single well-communicated system. The response mechanisms of the immune system are the innate or non-adapti ...
40. Lymphatics System
... A B cell identifies pathogens when antibodies on its surface bind to a specific foreign antigen This antigen/antibody complex is taken up by the B cell and processed by proteolysis into peptides (small pieces) As the activated B cell then begins to divide (“clonal expansion”), its offspring secrete ...
... A B cell identifies pathogens when antibodies on its surface bind to a specific foreign antigen This antigen/antibody complex is taken up by the B cell and processed by proteolysis into peptides (small pieces) As the activated B cell then begins to divide (“clonal expansion”), its offspring secrete ...
No Slide Title
... PRESENTING CELL BY ENDOCYTOSIS • DIGEST IN PHAGOLYSOSOME • FRAGMENTS COMBINE WITH PREFORMED MHC CLASS II • DISPLAYED ON PLASMA MEMBRANE • RECOGNIZED BY CD4 + CELLS ...
... PRESENTING CELL BY ENDOCYTOSIS • DIGEST IN PHAGOLYSOSOME • FRAGMENTS COMBINE WITH PREFORMED MHC CLASS II • DISPLAYED ON PLASMA MEMBRANE • RECOGNIZED BY CD4 + CELLS ...
Autoimmune Disease
... Glandular epithelial cells participate in the autoimmune disease process Epithelial cells produce a number of immunologically active mediators May serve as antigen-presenting cells Epithelial cell responses modulate mechanisms occurring in the salivary glands ...
... Glandular epithelial cells participate in the autoimmune disease process Epithelial cells produce a number of immunologically active mediators May serve as antigen-presenting cells Epithelial cell responses modulate mechanisms occurring in the salivary glands ...
Immunology_lecture13Transplantation
... • Difference of HLA types is the main cause of human grafts rejection ...
... • Difference of HLA types is the main cause of human grafts rejection ...
File - DOCEGG ANATOMY SITE docegg.com
... An important Rh-related problem occurs in pregnant Rh~ women who are carrying Rh+ babies. The first such pregnancy usually results in thedelivery of a healthy baby. Buc because the mother is sensitized by Rh+ antigens that have passed through the placenta into her bloodstream, she will form ;mti-Rh+ ...
... An important Rh-related problem occurs in pregnant Rh~ women who are carrying Rh+ babies. The first such pregnancy usually results in thedelivery of a healthy baby. Buc because the mother is sensitized by Rh+ antigens that have passed through the placenta into her bloodstream, she will form ;mti-Rh+ ...
serving up cancer cells - Ludwig Institute for Cancer Research
... patients’ T cells are activated by anti-CD47 antibodies, as they are in mice. The scientists are also planning animal studies to examine whether anti-CD47 antibody treatment can be powered up by drugs that activate T cells—such as murine versions of the experimental drug nivolumab, one of several “i ...
... patients’ T cells are activated by anti-CD47 antibodies, as they are in mice. The scientists are also planning animal studies to examine whether anti-CD47 antibody treatment can be powered up by drugs that activate T cells—such as murine versions of the experimental drug nivolumab, one of several “i ...
Phagocyte
Phagocytes are cells that protect the body by ingesting (phagocytosing) harmful foreign particles, bacteria, and dead or dying cells. Their name comes from the Greek phagein, ""to eat"" or ""devour"", and ""-cyte"", the suffix in biology denoting ""cell"", from the Greek kutos, ""hollow vessel"". They are essential for fighting infections and for subsequent immunity. Phagocytes are important throughout the animal kingdom and are highly developed within vertebrates. One litre of human blood contains about six billion phagocytes. They were first discovered in 1882 by Ilya Ilyich Mechnikov while he was studying starfish larvae. Mechnikov was awarded the 1908 Nobel Prize in Physiology or Medicine for his discovery. Phagocytes occur in many species; some amoebae behave like macrophage phagocytes, which suggests that phagocytes appeared early in the evolution of life.Phagocytes of humans and other animals are called ""professional"" or ""non-professional"" depending on how effective they are at phagocytosis. The professional phagocytes include many types of white blood cells (such as neutrophils, monocytes, macrophages, mast cells, and dendritic cells). The main difference between professional and non-professional phagocytes is that the professional phagocytes have molecules called receptors on their surfaces that can detect harmful objects, such as bacteria, that are not normally found in the body. Phagocytes are crucial in fighting infections, as well as in maintaining healthy tissues by removing dead and dying cells that have reached the end of their lifespan.During an infection, chemical signals attract phagocytes to places where the pathogen has invaded the body. These chemicals may come from bacteria or from other phagocytes already present. The phagocytes move by a method called chemotaxis. When phagocytes come into contact with bacteria, the receptors on the phagocyte's surface will bind to them. This binding will lead to the engulfing of the bacteria by the phagocyte. Some phagocytes kill the ingested pathogen with oxidants and nitric oxide. After phagocytosis, macrophages and dendritic cells can also participate in antigen presentation, a process in which a phagocyte moves parts of the ingested material back to its surface. This material is then displayed to other cells of the immune system. Some phagocytes then travel to the body's lymph nodes and display the material to white blood cells called lymphocytes. This process is important in building immunity, and many pathogens have evolved methods to evade attacks by phagocytes.