• Study Resource
  • Explore Categories
    • Arts & Humanities
    • Business
    • Engineering & Technology
    • Foreign Language
    • History
    • Math
    • Science
    • Social Science

    Top subcategories

    • Advanced Math
    • Algebra
    • Basic Math
    • Calculus
    • Geometry
    • Linear Algebra
    • Pre-Algebra
    • Pre-Calculus
    • Statistics And Probability
    • Trigonometry
    • other →

    Top subcategories

    • Astronomy
    • Astrophysics
    • Biology
    • Chemistry
    • Earth Science
    • Environmental Science
    • Health Science
    • Physics
    • other →

    Top subcategories

    • Anthropology
    • Law
    • Political Science
    • Psychology
    • Sociology
    • other →

    Top subcategories

    • Accounting
    • Economics
    • Finance
    • Management
    • other →

    Top subcategories

    • Aerospace Engineering
    • Bioengineering
    • Chemical Engineering
    • Civil Engineering
    • Computer Science
    • Electrical Engineering
    • Industrial Engineering
    • Mechanical Engineering
    • Web Design
    • other →

    Top subcategories

    • Architecture
    • Communications
    • English
    • Gender Studies
    • Music
    • Performing Arts
    • Philosophy
    • Religious Studies
    • Writing
    • other →

    Top subcategories

    • Ancient History
    • European History
    • US History
    • World History
    • other →

    Top subcategories

    • Croatian
    • Czech
    • Finnish
    • Greek
    • Hindi
    • Japanese
    • Korean
    • Persian
    • Swedish
    • Turkish
    • other →
 
Profile Documents Logout
Upload
Article 1: Mucosal Immunity and Vaccines
Article 1: Mucosal Immunity and Vaccines

Probiotic Induce Macrophage Cytokine Production via Activation of
Probiotic Induce Macrophage Cytokine Production via Activation of

... one of these routes. Signal transducer and activators of transcription (STATs) are cytoplasmic transcription factors that are key mediators of cytokine and growth factor signalling pathways. STAT-3 is implicated in macrophage cytokine signalling and production. It's well reported that the microbiota ...
et al - Sift Desk
et al - Sift Desk

... from pre-existing constituents (phytoanticipins), or synthesized de novo in response to pathogen intrusion (phytoalexins) (Laluk & Mengiste 2010) . Secondary metabolites implicated in defense against necrotrophs include derivatives of indole compounds: glucosinolates, phenylpropanoids, fatty acids, ...
The Phylogeny of Thymic Dependence The use of amphibians in
The Phylogeny of Thymic Dependence The use of amphibians in

Smart cell assays for immuno-oncology
Smart cell assays for immuno-oncology

... WEBINAR: Smart Cell Assays for Immuno-Oncology ...
Differential Mucosal IL-17 Expression in Two Gliadin
Differential Mucosal IL-17 Expression in Two Gliadin

... cells, has had major impact on understanding immune processes not readily explained by the Th1/Th2 paradigm [7]. Aside from their possible involvement in host defense against microbes, Th17 cells have been linked to the pathogenesis of inflammatory and autoimmune diseases such as collagen-induced ar ...
A human immunodeficiency virus type 1 Env–granulocyte
A human immunodeficiency virus type 1 Env–granulocyte

... investigate their potential utility as vaccines against HIV infection. Phase I clinical trials in healthy individuals vaccinated with different HIV-1 envelope protein (Env) poxvirus recombinants demonstrated that such a vaccine is safe and induces Author for correspondence : Mariano Esteban. ...
LESSON 2.5 WORKBOOK
LESSON 2.5 WORKBOOK

... Tumor cells most commonly resist apoptosis is by inhibiting pro-apoptotic proteins like p53. As a result upwards of 60-80% of cancers have mutations that inactivate p53. This shows just how important p53 is for controlling DNA damage in cells. When tumor cells are investigated to see what mutations ...
Crustacean hematopoiesis and the astakine cytokines.
Crustacean hematopoiesis and the astakine cytokines.

... crustacean vascular system should be classified as "incompletely closed" rather than “open”. In crustaceans, the circulatory system is used for oxygen transport via oxygen transport pigments of the hemocyanin protein family, which are present in plasma and not in cells. The crustacean circulatory sy ...
Effect of TGF-beta on interferon-gamma-induced HLA-DR
Effect of TGF-beta on interferon-gamma-induced HLA-DR

... There are indications that, in other cell types, IFNy may induce MHC class II antigens through activation of the PKC pathway,23 whereas TGF-/3 may be acting, in part, by PKC inhibition. 26 It has also been proposed that transcriptional regulation of HLA-DR antigen is modulated by PKC.27 Attempts to ...
The Lymphatic System
The Lymphatic System

... the bone marrow, and differentiate into two major functional cell types: 1. B lymphocytes, comprising the humoral immune system, whose ultimate function is the production of antibodies 2. T lymphocytes, comprising the cellular immune system, whose functions include a. Direct killing of foreign or in ...
Program outline
Program outline

... adds diagnostics, epidemiology, drug development, and vaccine design. 2. Complex infection models Infection dynamics becomes particularly evident in the setting of the natural infection when all players that determine the outcome of infection are present. Hence, important objectives are to (i) devel ...
A7 - Ummafrapp
A7 - Ummafrapp

... CD4(+) effector cells, based on cytokine production, nuclear receptors and signaling pathways, have been categorized into four subsets. T-helper-1 cells produce IFN-gamma, TNF-beta, lymphotoxin and IL-10; T-helper-2 cells produce IL-4, IL-5, IL-10, IL-13, IL-21 and IL-31; T-helper-3, or regulatory T ...
Document
Document

... ii. You will have B cells in there that are specific for these bacteria and they start to divide and make antibodies. iii. In here is where the immune response is taking place in these Peyer’s patches. The cells divide, differentiate into plasma cells, and these plasma cells migrate underneath the e ...
Perturbation of gut bacteria induces a coordinated cellular
Perturbation of gut bacteria induces a coordinated cellular

... competent immune system to successfully interact with the rich microbiota of their seawater environment.21 In the purple sea urchin, gene expression studies have identified an array of immune transcription factors, receptors, effectors and signal mediators that are expressed at this stage.10,22,23 Al ...
The Gell–Coombs classification of hypersensitivity reactions: a re
The Gell–Coombs classification of hypersensitivity reactions: a re

Glioblastoma-infiltrated innate immune cells resemble
Glioblastoma-infiltrated innate immune cells resemble

Arachidonic-acid-derived eicosanoids: roles in biology and
Arachidonic-acid-derived eicosanoids: roles in biology and

... acids [1–3]. AA-derived eicosanoids exert complex control over a wide range of physiological processes (Table 1). Many important aspects of immunity, such as cytokine production, antibody formation, differentiation, cell proliferation, migration and antigen presentation, are regulated by eicosanoids ...
Immune diseases And Children
Immune diseases And Children

... Cytokines: hormonal messengers for most of the biological effects in the immune system (e.g. cell mediated immunity and allergic responses) Cytokines can be proinflammatory or anti-inflammatory (but that promote allergic responses). T lymphocytes are a major source of cytokines: antigen specific rec ...
MHC class II Pathway
MHC class II Pathway

... cells and dendritic cells, and thymic epithelial cells. In MHC class II phagocytes such as macrophages and immature dendritic cells uptake entities by phagocytosis into phagosomes which fuse with lysosomes whose acidic enzymes cleave the uptaken protein into many different peptides interaction with ...
“The Role of Therapeutic Vaccination in HIV Cure Strategies” J.D.
“The Role of Therapeutic Vaccination in HIV Cure Strategies” J.D.

... Fate of “induced” cells Toxicity/off target effects Must eliminate/control “last virus”; potential role for immune surveillance, immune clearance Role for therapeutic vaccination? Cellular vs. Ab ...
larreaplus - Evolving Nutrition
larreaplus - Evolving Nutrition

... herpes simplex with dried extract from Melissa officinalis. Phytomedicine. 1994;1:25-31. ...
23_T-cell development_LA
23_T-cell development_LA

Immunology for CME 11.7.14.cdr
Immunology for CME 11.7.14.cdr

doc
doc

... enzymes play a critical role in cellular protection from cytotoxic and mutagenic effects of electrophiles so that alleles associated with impaired detoxification may confer an increase susceptibility to a wide range of diseases (Strange et al., 1998). Clapper and Szarka (1998) observed a critical ro ...
< 1 ... 217 218 219 220 221 222 223 224 225 ... 553 >

Immunomics

Immunomics is the study of immune system regulation and response to pathogens using genome-wide approaches. With the rise of genomic and proteomic technologies, scientists have been able to visualize biological networks and infer interrelationships between genes and/or proteins; recently, these technologies have been used to help better understand how the immune system functions and how it is regulated. Two thirds of the genome is active in one or more immune cell types and less than 1% of genes are uniquely expressed in a given type of cell. Therefore, it is critical that the expression patterns of these immune cell types be deciphered in the context of a network, and not as an individual, so that their roles be correctly characterized and related to one another. Defects of the immune system such as autoimmune diseases, immunodeficiency, and malignancies can benefit from genomic insights on pathological processes. For example, analyzing the systematic variation of gene expression can relate these patterns with specific diseases and gene networks important for immune functions.Traditionally, scientists studying the immune system have had to search for antigens on an individual basis and identify the protein sequence of these antigens (“epitopes”) that would stimulate an immune response. This procedure required that antigens be isolated from whole cells, digested into smaller fragments, and tested against T- and B-cells to observe T- and B- cell responses. These classical approaches could only visualize this system as a static condition and required a large amount of time and labor.Immunomics has made this approach easier by its ability to look at the immune system as a whole and characterize it as a dynamic model. It has revealed that some of the immune system’s most distinguishing features are the continuous motility, turnover, and plasticity of its constituent cells. In addition, current genomic technologies, like microarrays, can capture immune system gene expression over time and can trace interactions of microorganisms with cells of the innate immune system. New, proteomic approaches, including T-cell and B-cells-epitope mapping, can also accelerate the pace at which scientists discover antibody-antigen relationships.
  • studyres.com © 2026
  • DMCA
  • Privacy
  • Terms
  • Report