Evidence-based guidelines for the investigation of recurrent
... • Diagnosis: Traditionally, laparoscopy, HSG and/or hysteroscopy have been used to these uterine malformations in women with RM. • Ultrasound, and in particular 3D ultrasound, has become an accurate, reproducible, non-invasive, out-patient method for the diagnosis of congenital uterine anomalies (Sa ...
... • Diagnosis: Traditionally, laparoscopy, HSG and/or hysteroscopy have been used to these uterine malformations in women with RM. • Ultrasound, and in particular 3D ultrasound, has become an accurate, reproducible, non-invasive, out-patient method for the diagnosis of congenital uterine anomalies (Sa ...
Dendritic Cell-Based Immunotherapy
... immune resistance to tumors. CD8 + cytolytic T cells (CTLs) directly kill tumor cells expressing the appropriate MHC-peptide complexes, whereas NK and NKT cells eliminate targets that downregulate MHC class I expression to escape a CTL attack. CD4 + helper T cells assist in inducing and maintaining ...
... immune resistance to tumors. CD8 + cytolytic T cells (CTLs) directly kill tumor cells expressing the appropriate MHC-peptide complexes, whereas NK and NKT cells eliminate targets that downregulate MHC class I expression to escape a CTL attack. CD4 + helper T cells assist in inducing and maintaining ...
Type I
... Under some circumstances, immunity, rather than providing protection, produces damaging and sometimes fatal results. Such deleterious reactions are known collectively as hypersensitivity reactions, but it should be remembered that they differ from protective immune reactions only in that they are ex ...
... Under some circumstances, immunity, rather than providing protection, produces damaging and sometimes fatal results. Such deleterious reactions are known collectively as hypersensitivity reactions, but it should be remembered that they differ from protective immune reactions only in that they are ex ...
Antigen Processing PPT
... • Antigen presentation does not require metabolically-active cells • Antigen processing involves the lysosomal system • Catabolism reduces antigens to peptides • Because extracellular antigens are dealt with by the lysosomal system, lysosomal antigen processing is part of the EXOGENOUS antigen proce ...
... • Antigen presentation does not require metabolically-active cells • Antigen processing involves the lysosomal system • Catabolism reduces antigens to peptides • Because extracellular antigens are dealt with by the lysosomal system, lysosomal antigen processing is part of the EXOGENOUS antigen proce ...
Judging a virus by its cover - Journal of Clinical Investigation
... tion, although somatic hypermutation does occur after days 6–8 in the germinal centers (15, 16). The high, germline-encoded affinities enable VSV to elicit protective neutralizing IgM antibodies on days 3–4. These IgM antibodies are generated in a helper T cell–independent fashion (12). Hence, this ...
... tion, although somatic hypermutation does occur after days 6–8 in the germinal centers (15, 16). The high, germline-encoded affinities enable VSV to elicit protective neutralizing IgM antibodies on days 3–4. These IgM antibodies are generated in a helper T cell–independent fashion (12). Hence, this ...
here
... Ticks harbor other pathogenic bacteria, viruses and protozoa More than one pathogen may be transmitted during bite; exception to the rule All the pathogen share and have in common long replication cycles… Possibility of sexual and vertical transmission (Syphilis as a case example) between sex and ...
... Ticks harbor other pathogenic bacteria, viruses and protozoa More than one pathogen may be transmitted during bite; exception to the rule All the pathogen share and have in common long replication cycles… Possibility of sexual and vertical transmission (Syphilis as a case example) between sex and ...
α and L-selectin, but not CD103 or CD34, are IL-7R
... model has been utilized successfully to highlight the role of B cells, CD40 ligand and mast cells and the effects of therapeutic interventions (blocking histamine and/or platelet activating factor) on peanut-induced anaphylactic responses [5,6]. In a related fatal PIA model, the importance of mast c ...
... model has been utilized successfully to highlight the role of B cells, CD40 ligand and mast cells and the effects of therapeutic interventions (blocking histamine and/or platelet activating factor) on peanut-induced anaphylactic responses [5,6]. In a related fatal PIA model, the importance of mast c ...
Mucosal Immunology
... least three such clusters (referred to in some publications as enterotypes) primarily on the basis of the abundance of Bacteroides, Prevotella, and Ruminococcus (Arumugam et al., 2011). However, it is not yet clear what significance such clustering has for characterizing the entirety of an individua ...
... least three such clusters (referred to in some publications as enterotypes) primarily on the basis of the abundance of Bacteroides, Prevotella, and Ruminococcus (Arumugam et al., 2011). However, it is not yet clear what significance such clustering has for characterizing the entirety of an individua ...
Rapid early innate control of hepatitis C virus during IFN
... To determine the role of CD4+ T cells in viral clearance, we performed a detailed analysis in the 33 chronically HCV-infected consecutively treated patients whom we had treated for HCV (patient details are shown in Table 1). All 33 patients demonstrated robust responses to the control recall antigen ...
... To determine the role of CD4+ T cells in viral clearance, we performed a detailed analysis in the 33 chronically HCV-infected consecutively treated patients whom we had treated for HCV (patient details are shown in Table 1). All 33 patients demonstrated robust responses to the control recall antigen ...
Anti-Viral Vaccines - OIT Web Services
... (1) The gene (YFG) is flanked with vaccinia DNA sequences, especially the vaccinia promoters and multicloning sites for cleavage and ligation. The following are often included: The promoters are necessary DNA sequences because the endogenous viral RNA polymerase binds here to initiate transcriptio ...
... (1) The gene (YFG) is flanked with vaccinia DNA sequences, especially the vaccinia promoters and multicloning sites for cleavage and ligation. The following are often included: The promoters are necessary DNA sequences because the endogenous viral RNA polymerase binds here to initiate transcriptio ...
![alveolar macrophages [2], as well as from the pulmonary](http://s1.studyres.com/store/data/008916278_1-6c4bb22cb689cb304002bf62284b81e5-300x300.png)
alveolar macrophages [2], as well as from the pulmonary
... In our study, we found that hyperplastic type II pneumocytes were the main source of IL-10 in the lung tissue specimens from patients with IPF [1]. One can speculate that at least a part of IL-10 produced in the lung in the course of IPF could circulate in the bloodstream, and thus could participate ...
... In our study, we found that hyperplastic type II pneumocytes were the main source of IL-10 in the lung tissue specimens from patients with IPF [1]. One can speculate that at least a part of IL-10 produced in the lung in the course of IPF could circulate in the bloodstream, and thus could participate ...
The Cellular Biology of the Reed-Sternberg Cell
... OR STUDENTS OF the history of medicine, the evolution of our understanding of Hodgkin's disease (HD) has long proved a compelling subject. Traced in the chronology of this disorder, from its first descriptions, through the refinements in its classification, to its medical and radiotherapeutic cure, ...
... OR STUDENTS OF the history of medicine, the evolution of our understanding of Hodgkin's disease (HD) has long proved a compelling subject. Traced in the chronology of this disorder, from its first descriptions, through the refinements in its classification, to its medical and radiotherapeutic cure, ...
Lecture 12
... 6) What does nitrogenase use as a source of electrons? Why doesn't it just use NADH? What are at least two possible sources for these electrons? 7) Why is the study of microorganisms like Rhizobium so important to agriculturists? 8) Describe the "dialog" between Rhizobium sp. and its host pea plant. ...
... 6) What does nitrogenase use as a source of electrons? Why doesn't it just use NADH? What are at least two possible sources for these electrons? 7) Why is the study of microorganisms like Rhizobium so important to agriculturists? 8) Describe the "dialog" between Rhizobium sp. and its host pea plant. ...
Chapter_24_HB_Immune
... Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
... Copyright © 2003 Pearson Education, Inc. publishing as Benjamin Cummings ...
in Children with Autism.
... TNF-a) levels, but antigen-specific serum IgE levels were not elevated. All chemicals induced significant increases in numbe of lymphocytes and surface antigen expression of B cells. ...
... TNF-a) levels, but antigen-specific serum IgE levels were not elevated. All chemicals induced significant increases in numbe of lymphocytes and surface antigen expression of B cells. ...
From evolutionary genetics to human immunology: how selection
... microbial molecules are often referred to as pathogen-associated molecular patterns (PAMPs)9,10,140. PRRs can be located on or in cells, such as macrophages, dendritic cells or natural killer cells, or can be secreted into the bloodstream and tissue fluids. After sensing a PAMP, PRRs trigger diverse ...
... microbial molecules are often referred to as pathogen-associated molecular patterns (PAMPs)9,10,140. PRRs can be located on or in cells, such as macrophages, dendritic cells or natural killer cells, or can be secreted into the bloodstream and tissue fluids. After sensing a PAMP, PRRs trigger diverse ...
Glial Cells: The Other Cells of the Nervous System
... are the cause of neurodegenerative diseases and good animal models are now available to study myelin producing genes. In mice, mutation in the MBP gene causes the shiverer (shi) and myelin-deficient (mId) phenotype, where animals show uncontrollable shivering and convulsions leading to death between ...
... are the cause of neurodegenerative diseases and good animal models are now available to study myelin producing genes. In mice, mutation in the MBP gene causes the shiverer (shi) and myelin-deficient (mId) phenotype, where animals show uncontrollable shivering and convulsions leading to death between ...
Synovial lining cell hyperplasia in rheumatoid arthritis
... characteristic ultrastructure of type A synovial lining cells.'5 16 Thus in the normal joint the type A cells appear to derive from bone marrow precursors. Further evidence for the recruitment of cells to the joint comes from experiments in guinea pigs using an antigen induced model of arthritis. 17 ...
... characteristic ultrastructure of type A synovial lining cells.'5 16 Thus in the normal joint the type A cells appear to derive from bone marrow precursors. Further evidence for the recruitment of cells to the joint comes from experiments in guinea pigs using an antigen induced model of arthritis. 17 ...
Plasma cells for a lifetime?
... resulting in five- to tenfold higher numbers of persisting plasma cells in the bone marrow as compared to a primary response [18]. In a second line of experiments, Ochsenbein et al. [17] showed that spleen and bone marrow cells from VSV-immunized mice, when transferred into non-irradiated hosts, gen ...
... resulting in five- to tenfold higher numbers of persisting plasma cells in the bone marrow as compared to a primary response [18]. In a second line of experiments, Ochsenbein et al. [17] showed that spleen and bone marrow cells from VSV-immunized mice, when transferred into non-irradiated hosts, gen ...
2014 issue of Current Diabetes Reports
... Penetration of Peri-Islet BM Barrier Upon extravasation from blood vessels, the leukocytes migrate through the thin IM and must then penetrate the barrier presented by the peri-islet BM. Immunofluorescence studies have revealed a global loss of peri-islet IM and BM components only at sites of leukoc ...
... Penetration of Peri-Islet BM Barrier Upon extravasation from blood vessels, the leukocytes migrate through the thin IM and must then penetrate the barrier presented by the peri-islet BM. Immunofluorescence studies have revealed a global loss of peri-islet IM and BM components only at sites of leukoc ...
Mesenchymal stem cells in immunoregulation
... from different studies. Once this issue is solved, many downstream signals could be the potential research targets, including IL-2-related suppressive signals, Smad-mediated IL-10 secretion and costimulatory molecule-induced antigen-specific unresponsiveness, such as CD28 and CTLA4.39–41 Other expla ...
... from different studies. Once this issue is solved, many downstream signals could be the potential research targets, including IL-2-related suppressive signals, Smad-mediated IL-10 secretion and costimulatory molecule-induced antigen-specific unresponsiveness, such as CD28 and CTLA4.39–41 Other expla ...
Peptides in Neurons and Microglia Inducing the Synthesis of
... immunological reaction that encompasses both neural components and peripheral immune system cells. Within the mammalian CNS, resident glial cells, including astrocytes and microglia, have been shown to initiate a characteristic innate immune response by producing and releasing antimicrobial peptides ...
... immunological reaction that encompasses both neural components and peripheral immune system cells. Within the mammalian CNS, resident glial cells, including astrocytes and microglia, have been shown to initiate a characteristic innate immune response by producing and releasing antimicrobial peptides ...
Artículo de revisión The ocular surface: from physiology to the ocular
... The conjunctiva is a lining of the outer portion of the eye. Conjunctival tissue begins from the anterior portion of the limbus, and ends at the eyelids margin. Anatomically, conjunctiva is divided into three regions: i) the bulbar conjunctiva, which covers the anterior portion of the sclera; ii) th ...
... The conjunctiva is a lining of the outer portion of the eye. Conjunctival tissue begins from the anterior portion of the limbus, and ends at the eyelids margin. Anatomically, conjunctiva is divided into three regions: i) the bulbar conjunctiva, which covers the anterior portion of the sclera; ii) th ...
Enhancement of an anti-tumor immune response by transient
... hosts could both selectively and transiently inhibit the development and turnover of mTECs with potential to alter central T cell tolerance. To this end, we performed in vivo RANKL blockade in adult mice and investigated its effects on both TECs and developing thymocytes.We show that anti-RANKL trea ...
... hosts could both selectively and transiently inhibit the development and turnover of mTECs with potential to alter central T cell tolerance. To this end, we performed in vivo RANKL blockade in adult mice and investigated its effects on both TECs and developing thymocytes.We show that anti-RANKL trea ...