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Lyme Borreliosis is a complex multisystem illness caused by
Lyme Borreliosis is a complex multisystem illness caused by

... evidence point to specific spirochetal strategies to evade immune responses as well as antibiotic therapy. These strategies may include immune avoidance, evasion through molecular morphology mediated by altered gene expression, direct cytotoxicity, as well as immune modulation. As described previous ...
Backup of 43
Backup of 43

... A. Activation of T cells T cells respond only to antigenic epitopes displayed on the surfaces of the body’s own cells The presence of a T cell surface molecule called CD4 enhances the interactions between the cells and antigen presenting cells (APC) The MHC-antigen complex displayed on the infected ...
Mechanisms of Autoimmunity
Mechanisms of Autoimmunity

A Newly-Discovered Tumor Suppressor Gene Affects Melanoma
A Newly-Discovered Tumor Suppressor Gene Affects Melanoma

... identified as a major oncogene that contributes to the unchecked growth of cells. When they restored the production of the protein in melanoma cells that harbored RASA2 mutations, these cells stopped growing and eventually died. Patients with dysfunctional RAS pathways tend to have a worse prognosis ...
functions occur only through constant mutualism with the INTRODUCTION
functions occur only through constant mutualism with the INTRODUCTION

... intestinal resident cells, commensal microbiota, local immune cells, and metabolites. Unfavorable alterations to these interactions are thought to be responsible for the development of inflammatory bowel disease (IBD). IBD includes two major disorders: Crohn’s disease (CD) and ulcerative colitis (UC ...
The Immune System
The Immune System

... around the body; activation and clonal selection of effector B cells happens in this response Cell-mediated immune response: the body searches for and destroys antigens; activation and clonal selection of cytotoxic T cells happens in this response ...
brain
brain

...  Message go from your brain down to your spinal cord. • Big rope of nerve cells • Runs along the inside of your back bone • Connects to neurons all over your body ...
here. - Genomax Technologies Malaysia
here. - Genomax Technologies Malaysia

... capabilities that distinguish cancer from normal tissue. The Hallmarks help explain the complexities of cancer by describing a common set of capabilities present in cancer cells. These processes that, if unstopped, will allow cancer cells to thrive and proliferate in the unique tumor environment the ...
PLP 3104
PLP 3104

... Categories of hormoneproductin cells in insects 1) Endocrine glands -- producing hormones and releasing them into the circulatory system. 2) Neurohemal organs -- store their secretory product in a special chamber until stimulated to release it by a signal from the nervous system (or another hormone ...
Group 3 final case - Cal State LA
Group 3 final case - Cal State LA

... The most common treatment for this disease is a bone marrow transplant. If we act quickly and start treatment immediately, the prognosis might be optimistic. Those who undergo successful bone marrow transplants tend to leave normal lives. Without any treatment, prognosis is very dim. I ...
Tissue of the teeth
Tissue of the teeth

... 8. Immune system interactions  The complement system is a series of 25 proteins manufactured in the liver and are are activated by, and work with, (i.e. complement) antibodies Function of complement: ...
Cancer Immune Therapy in Clinic: 2016
Cancer Immune Therapy in Clinic: 2016

... progression by producing TGF-β, interleukin (IL)-10 as well as cytotoxic T lymphocyte-associated protein 4 (CTLA-4) [7,8]. Tumor cells can reduce T-cell-mediated recognition by changing Human Leucocyte Antigen (HLA) class I expression which present processed tumor antigen to T cell [9]. Although thi ...
Lecture on Innate Immunity and Inflammation
Lecture on Innate Immunity and Inflammation

... • Monocytes are multi-potential, depending on cytokine signals: +IFN-γ: assume a vigorous killing phenotype similar to neutrophils +IL-4: “alternatively activated macrophages”; tissue repair, barrier immunity +IL-10: assume a wound-healing type phenotype (to clean up after infection is cleared) ...
Lecture 3
Lecture 3

... – in more severe persistent irritation ...
Chapter 15
Chapter 15

... 2.  Cytotoxic T cells (CD8 or T C )  destroy foreign  or abnormal cells by secreting perforins that lyse  cells  Video  3.  Delayed hypersensitivity cells (T D ) responsible  for allergies occurring several hours or days after  contact  4.  T suppressor cells (T S ) limit the actions of other  T cel ...
word - My eCoach
word - My eCoach

... c. a feedback loop to maintain homeostasis. d. an enzyme-catalyzed biochemical reaction. 30. Which statement is true about non-specific defenses? a. They play a minor role in the body’s defense against infection. b. They distinguish between different kinds of infectious agents. c. They do not work a ...
Cellular Biology
Cellular Biology

... Glycoproteins on the surface of all human cells (except RBCs)  Also referred to as human leukocyte antigens (HLAs)  Dendritic cells – antigen presenting leukocyte found in mucosa and lymphoid tissues that initiate a primary immune response. ...
OBJ - Physiology
OBJ - Physiology

... o Plant defenses against pathogens include molecular recognition systems with systemic responses; infection triggers chemical responses that destroy infected and adjacent cells, thus localizing the effects. o Vertebrate immune systems have nonspecific and nonheritable defense mechanisms against path ...
Acting Out the Immune Response
Acting Out the Immune Response

... allergy. Recent scientific studies have shown that there has been an increasing incidence of allergy in developed nations such as the United States (Nova). Although the exact cause of the increase in allergy is not known, a number of suggestions have been proposed based on studies conducted by vario ...
cell-mediated immunity.
cell-mediated immunity.

... Types of white blood cell There are several types of white blood cell, each with a different function but there are two main groups. These are: • phagocytes or macrophages - involved in the non-specific immune response, • Lymphocytes - involved in the specific immune response. Our focus for today P ...
Blank UbD Planning Template
Blank UbD Planning Template

... 3.1.B.B1. Explain that the information passed from parents to offspring is transmitted by means of genes which are coded in DNA molecules. Explain how mutations can alter genetic information and the possible consequences on resultant cells. 3.1.12.B3. Explain the impact of environmental factors on g ...
B cells
B cells

... 5)Natural killer (NK) largest T cell.Interferons cause cytotoxic granule release 6) Antigen-presenting cell (APC) ...
Nature of The Immune System Specific Immunity
Nature of The Immune System Specific Immunity

Can Parkinsons disease be cured by an injection of fetal
Can Parkinsons disease be cured by an injection of fetal

... continuously after about age 40. Unfortunately for those affected, the treatments available usually have a relatively short effective duration – after which a sort-of ‘crest’ is passed where the disease progression outstrips the ability for current therapies to prevent further decline. Some new rese ...
Answers to Mastering Concepts Questions
Answers to Mastering Concepts Questions

... inflammation. These immune reactions are helpful because they recruit other immune components, help clear debris, and create an environment hostile to microorganisms around the site of injury or infection. If a drug targets and kills mast cells, then the inflammation response would not occur, and th ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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