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PDF - The Journal of Immunology
PDF - The Journal of Immunology

... It would of course be a mistake to ignore the important role that endogenous signs of cellular distress might play in provoking immune responses. Recent evidence has suggested that stressed cells are capable of producing a wide variety of signals to the immune system. For example, the MHC class I-li ...
Inflammation: A Common Denominator of Disease
Inflammation: A Common Denominator of Disease

... cakes, soft drinks, candy, etc. In addition, sugar and white flour cause inflammation and disease by forming AGEs. AGEs are produced when a protein reacts with sugar, resulting in damaged, cross-linked proteins. As the body tries to protect you by breaking these AGEs apart, immune cells secrete larg ...
Serotonin, also known as 5-HT (5
Serotonin, also known as 5-HT (5

... a nerve fires at a synapse, the neurotransmitter must be taken back up by the original neuron. This so-called “re-uptake” is an extremely important aspect of nervous system function. Different neurotransmitters are found in different parts of the nervous system. Serotonin is found in parts of the br ...
VPM 403 Lecture Note
VPM 403 Lecture Note

... RNA signifies to the cell that it has been infected. ...
Respiratory and Metabolic Impacts of Crustacean Immunity: Are
Respiratory and Metabolic Impacts of Crustacean Immunity: Are

... Synopsis Extensive similarities in the molecular architecture of the crustacean immune system to that of insects give credence to the current view that the Hexapoda, including Insecta, arose within the clade Pancrustacea. The crustacean immune system is mediated largely by hemocytes, relying on suit ...
Biology – The Search for Better Health
Biology – The Search for Better Health

... two different types of lymphocytes, B cells and T cells, which are specific to the invading particle. These lymphocytes work together and launch an intensive attack to try and rid the body of this foreign material. In the process, cells that remember the specific antigens are also produced, so that ...
Systems biology in vaccine design
Systems biology in vaccine design

... Immune response and vaccination principles Vaccines are currently most effective treatments in preventing a number of infectious diseases and minimizing their impact on human or animal populations. A vaccine is a biological preparation that improves immunity to a particular disease upon administrati ...
Iannello, A. and D. H. Raulet. 2014. Immunosurveillance of senescent cancer cells by natural killer cells. Oncoimmunology 3:e27616 
Iannello, A. and D. H. Raulet. 2014. Immunosurveillance of senescent cancer cells by natural killer cells. Oncoimmunology 3:e27616 

... senescent tumors. Both these pathways, which are involved in the mobilization of NK cells and their ability to recognize malignant cells, turned out to be required for NK cell-dependent tumor elimination. Our study highlights one mechanism whereby p53-induced cellular senescence ...
Internal Regulation
Internal Regulation

... hormones in response to hormones released by the hypothalamus. Posterior pituitary develops as an extension of the hypothalamus: it stores and secretes (but does not synthesize) hormones. ...
Robertson et al. 2003 Seminal priming
Robertson et al. 2003 Seminal priming

... Conventional belief holds that an immune response to ejaculate antigens should interfere with fertilisation and establishment of pregnancy. However, emerging evidence now supports the opposing view */that insemination acts to activate maternal immune mechanisms exerting a positive effect on reproduc ...
Selection of rules
Selection of rules

... We want to understand whether those immune system mechanisms can hold for social systems, since social systems are also constantly confronted with disturbances, often as a result of the conflict between individual and collective rationalities. One might argue that social systems are not organisms, a ...
THE BLOOD BRAIN BARRIER AND LYSOSOMAL STORAGE
THE BLOOD BRAIN BARRIER AND LYSOSOMAL STORAGE

Slide 1
Slide 1

... environment to another organism is called an infectious disease. • Infectious diseases are spread by direct contact with the infected organism, through water and air, on food, by contact with contaminated objects, and by disease-carrying organisms called biological vectors. ...
20 Chapter
20 Chapter

... environment to another organism is called an infectious disease. • Infectious diseases are spread by direct contact with the infected organism, through water and air, on food, by contact with contaminated objects, and by disease-carrying organisms called biological vectors. ...
Immune system
Immune system

... forming trabeculae. These together with the reticular cells network form a support for a great lot of cells. Two types of tissue enter in the spleen structure : the tissue responsible for grown old blood cells destruction and urgent generation of new erythrocytes, platelets and granulocytes (red pul ...
Psychology - Bideford College Sixth Form
Psychology - Bideford College Sixth Form

... 4. When something stimulates a neuron (what we call an excitatory neurotransmitter), and positive ions flood inside the cell body, what does it create? ...
Transfer Factor - GlobalSuccess4Life.com
Transfer Factor - GlobalSuccess4Life.com

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Systemic_Lupus_Erythematosus

Depression - A Harvest of Health
Depression - A Harvest of Health

... and other related compounds—appear to modulate serotonin, dopamine and norepinephrine, making these mood-enhancing neurotransmitters more available to the brain.6 Studies indicate that St. John’s wort works as well as certain antidepressant medications but without some of the common side effects the ...
Dermatrust report, March 2013 During last year my research has
Dermatrust report, March 2013 During last year my research has

... antigen into the skin of the forearm and subsequently sampling the injected skin site by either taking a biopsy or performing a suction blister. VZV is the virus responsible for chickenpox, reactivation of which in later life causes shingles. Our data indicates that old individuals do not mount effe ...
Stem cell therapy for autism spectrum disorders Dario Siniscalco,
Stem cell therapy for autism spectrum disorders Dario Siniscalco,

Presentation
Presentation

The Nervous System
The Nervous System

... membrane receptors, there are two possible outcomes for postsynaptic membrane – Excitatory postsynaptic potential • Na+ gates open; membrane becomes depolarized; action potential is generated. – Inhibitory postsynaptic potential • K+ gates open; membrane becomes more polarized (hyperpolarized); inhi ...
Adaptive Immune System Chapter 16
Adaptive Immune System Chapter 16

... • Act as a surveillance system that screens the tissues of the body for foreign antigens • Composed of lymphatic vessels and lymphatic cells, tissues, and organs ...
Zinc Importer ZIP2 and the Dendritic Cell Response to Histoplasma
Zinc Importer ZIP2 and the Dendritic Cell Response to Histoplasma

... Joseph Fixler, Michael Horwath, George Deepe, Division of Infectious Diseases, University of Cincinnati College of Medicine ...
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Psychoneuroimmunology



Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.
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