Immunology for physicists - Laboratoire de Physique Statistique
... the chemistry more phenomenological laws that govern the growth and differentiation (or maturation) of lymphocytes into cells with specialized functions, such as plasma cells that secrete antibody at very high rates. We also look at a phenomenon, known as affinity maturation, by which the immune sys ...
... the chemistry more phenomenological laws that govern the growth and differentiation (or maturation) of lymphocytes into cells with specialized functions, such as plasma cells that secrete antibody at very high rates. We also look at a phenomenon, known as affinity maturation, by which the immune sys ...
Pathomechanisms for Cytopenia in Active SLE
... • Pathogenic auto-antibodies , and immune complexes bind to target tissues with activation of complement and phagocytic cells. • Complement, and immune cells lead to release of chemotaxins, cytokines, chemokines, vasoactive peptides, and destructive enzymes. ...
... • Pathogenic auto-antibodies , and immune complexes bind to target tissues with activation of complement and phagocytic cells. • Complement, and immune cells lead to release of chemotaxins, cytokines, chemokines, vasoactive peptides, and destructive enzymes. ...
What the Endocrine System Does
... • The foundation of the endocrine system is the glands and hormones. • As the body’s chemical messengers , hormones transfer information and instructions from one set of cells to another. • Hormone levels can be influenced by factors such as stress , infection , and changes in the balance of fluid a ...
... • The foundation of the endocrine system is the glands and hormones. • As the body’s chemical messengers , hormones transfer information and instructions from one set of cells to another. • Hormone levels can be influenced by factors such as stress , infection , and changes in the balance of fluid a ...
Phagocyte-specific S100 proteins are released from affected
... (ELISA) system established in our laboratory, as described previously [8]. Concentrations of MRP8/14 were determined by a double sandwich ELISA system established in our laboratory, as described previously [19]. The readers of the laboratory assay were blinded for the diagnosis and the inflammation ...
... (ELISA) system established in our laboratory, as described previously [8]. Concentrations of MRP8/14 were determined by a double sandwich ELISA system established in our laboratory, as described previously [19]. The readers of the laboratory assay were blinded for the diagnosis and the inflammation ...
Influence of honey in mice bearing Ehrlich carcinoma
... traditional medicine have been accepted currently as one of the main sources of cancer chemoprevention drug discovery and development (Abdullaev, 2001). • Antioxidants play an important role in inhibiting and scavenging radicals, thus providing protection to humans against infection and degenerative ...
... traditional medicine have been accepted currently as one of the main sources of cancer chemoprevention drug discovery and development (Abdullaev, 2001). • Antioxidants play an important role in inhibiting and scavenging radicals, thus providing protection to humans against infection and degenerative ...
epidemiology and control of diphtheria and tetanus
... “ Tetanus is not simply a disorder of motor function. The autonomic N.S. is also rendered unstable by the action of the toxin.” - Death occurs mainly due to either asphyxia or autonomic instability (e.g. sudden changes in pulse rate, bl.P., and cardiac output). - Serious cardiac arrythmias, excessiv ...
... “ Tetanus is not simply a disorder of motor function. The autonomic N.S. is also rendered unstable by the action of the toxin.” - Death occurs mainly due to either asphyxia or autonomic instability (e.g. sudden changes in pulse rate, bl.P., and cardiac output). - Serious cardiac arrythmias, excessiv ...
Protozoan Parasite Glycosylphosphatidylinositol Anchors from a
... Cells of the macrophage lineage exposed to these microbial components synthesize high levels of pro-inflammatory cytokines, including IL-12 and TNF-␣, two mediators that appear to be important for the initiation of IFN-␥ synthesis by NK cells (8). Recognition of bacterial glycolipids by IFN-␥-expose ...
... Cells of the macrophage lineage exposed to these microbial components synthesize high levels of pro-inflammatory cytokines, including IL-12 and TNF-␣, two mediators that appear to be important for the initiation of IFN-␥ synthesis by NK cells (8). Recognition of bacterial glycolipids by IFN-␥-expose ...
Nervous System Organization and Components
... I. Systems of Internal Communications The survival of a multicellular organism depends on regulation and integration of activities of its cells. There are two systems that serve as means of internal communication within the organism. The nervous system acts rapidly, for a short duration and endocrin ...
... I. Systems of Internal Communications The survival of a multicellular organism depends on regulation and integration of activities of its cells. There are two systems that serve as means of internal communication within the organism. The nervous system acts rapidly, for a short duration and endocrin ...
antigens
... reaction with the Abs so produced. Haptens / Incomplete Ag - Substances which can not induce Ab formation by themselves but can react specifically with Abs. ...
... reaction with the Abs so produced. Haptens / Incomplete Ag - Substances which can not induce Ab formation by themselves but can react specifically with Abs. ...
The Open Nutraceuticals Journal
... able to stimulate myeloid immune cells associated with the gut. One source of orally bioavailable myeloid cell-activating substances are immune stimulatory carbohydrates, some of which are a major component in Chinese medicine [13-17]. Immune stimulatory carbohydrates and their complex polymers, pol ...
... able to stimulate myeloid immune cells associated with the gut. One source of orally bioavailable myeloid cell-activating substances are immune stimulatory carbohydrates, some of which are a major component in Chinese medicine [13-17]. Immune stimulatory carbohydrates and their complex polymers, pol ...
Stem cells and aging from a quasiimmortal point of view
... increasing age, functionality and number of somatic stem cells appears to decline [38] (Fig. 2A) as has been shown in several different stem cell systems including the skin [40], hematopoietic [41], neural [42, 43], and muscular stem cells [44]. As seen either in progenitor cell number and/or differ ...
... increasing age, functionality and number of somatic stem cells appears to decline [38] (Fig. 2A) as has been shown in several different stem cell systems including the skin [40], hematopoietic [41], neural [42, 43], and muscular stem cells [44]. As seen either in progenitor cell number and/or differ ...
... levels of co-stimulatory molecules, release inflammatory cytokines and mediators and promote extracellular matrix breakdown. Classically activated macrophages have been shown to be mediators of immunopathology in several autoimmune diseases. Alternatively activated macrophages contribute to homeosta ...
Cell-based strategies/therapies for cartilage - HAL
... function of MSCs as well as matrix metalloproteinases (MMPs) and tissue inhibitors of MMP (TIMPs) [25,26], while SDF-1 and Sfrp2 have been identified as anti-apoptotic factors [27,28]. The combination of the different functional roles of secreted factors may be of interest for joint tissue regenerat ...
... function of MSCs as well as matrix metalloproteinases (MMPs) and tissue inhibitors of MMP (TIMPs) [25,26], while SDF-1 and Sfrp2 have been identified as anti-apoptotic factors [27,28]. The combination of the different functional roles of secreted factors may be of interest for joint tissue regenerat ...
File - Indian Institute of Toxicology Research
... evidences have shown a link between endocrine system and immune system; several hormones exert their effects on immune cell types and haematopoietic cells through their receptors. Enhanced PRL and GH are associated with a number ...
... evidences have shown a link between endocrine system and immune system; several hormones exert their effects on immune cell types and haematopoietic cells through their receptors. Enhanced PRL and GH are associated with a number ...
STING Contributes to Antiglioma Immunity via Triggering Type I IFN
... In addition to the ability of type I IFNs to interfere with viral infection, they also enhance antitumor host immunity. Indeed, loss of type I IFN signaling promotes tumorigenesis in a variety of tumor types, such as sarcomas (1), melanomas (2, 3), and gliomas as we have reported previously (4). Alt ...
... In addition to the ability of type I IFNs to interfere with viral infection, they also enhance antitumor host immunity. Indeed, loss of type I IFN signaling promotes tumorigenesis in a variety of tumor types, such as sarcomas (1), melanomas (2, 3), and gliomas as we have reported previously (4). Alt ...
The hepatitis C virus enigma
... profile). Th1 cytokines, e.g. IL-2, IFN-g and tumour necrosis factor (TNF-) a, activate several antiviral mechanisms, such as enhancing immune recognition by increasing the expression of HLA-molecules on infected cells or activating CD81 T cells and NK cells. Several studies have shown a correlation ...
... profile). Th1 cytokines, e.g. IL-2, IFN-g and tumour necrosis factor (TNF-) a, activate several antiviral mechanisms, such as enhancing immune recognition by increasing the expression of HLA-molecules on infected cells or activating CD81 T cells and NK cells. Several studies have shown a correlation ...
Glioblastoma-infiltrated innate immune cells resemble
... glioblastoma patients, we identified three myeloid cell populations: the predominant monocytic subset of MDSCs (CD33+CD11b+CD14highCD15–), a minor population of neutrophilic MDSCs expressing CD33+CD11b+CD14lowCD15+, and CD11b+CD14low monocytes (Supplemental Figure 1, C and D). We also observed an in ...
... glioblastoma patients, we identified three myeloid cell populations: the predominant monocytic subset of MDSCs (CD33+CD11b+CD14highCD15–), a minor population of neutrophilic MDSCs expressing CD33+CD11b+CD14lowCD15+, and CD11b+CD14low monocytes (Supplemental Figure 1, C and D). We also observed an in ...
Chronic granulomatous disease needs extra attention
... immune deficiencies. However, it will be tough to consider this point in an adolescent patient with UC alone, normal physical development and negative history of recurrent infections like our patient. Gastrointestinal tract involvement in CGD patients causes significant morbidity and mortality. Its ...
... immune deficiencies. However, it will be tough to consider this point in an adolescent patient with UC alone, normal physical development and negative history of recurrent infections like our patient. Gastrointestinal tract involvement in CGD patients causes significant morbidity and mortality. Its ...
sistema inmune2
... Specific Defenses Four Properties of Immunity Memory Some active lymphocytes (memory cells): – stay in circulation – provide immunity against new exposure ...
... Specific Defenses Four Properties of Immunity Memory Some active lymphocytes (memory cells): – stay in circulation – provide immunity against new exposure ...
12 Physiology of autonomic nervous system
... Generally the two divisions have chains of two motor neurons that innervate same visceral organs but cause essentially opposite effects If one division stimulates certain smooth muscle to contract or a gland to secrete, the other division inhibits that action Through this process of duel innervation ...
... Generally the two divisions have chains of two motor neurons that innervate same visceral organs but cause essentially opposite effects If one division stimulates certain smooth muscle to contract or a gland to secrete, the other division inhibits that action Through this process of duel innervation ...
HIV vaccine development at the turn of the 21st century
... The importance of innate immunity Finally, the macaque/SIV model has been instrumental in outlining the importance of innate immune responses in protection against SIV/SHIV experimental infection. In the experiment of Sui et al. [23 ], the use of Toll-like receptor agonists and IL-15 cytokine as an ...
... The importance of innate immunity Finally, the macaque/SIV model has been instrumental in outlining the importance of innate immune responses in protection against SIV/SHIV experimental infection. In the experiment of Sui et al. [23 ], the use of Toll-like receptor agonists and IL-15 cytokine as an ...
Psychoneuroimmunology
Psychoneuroimmunology (PNI), also referred to as psychoendoneuroimmunology (PENI), is the study of the interaction between psychological processes and the nervous and immune systems of the human body. PNI takes an interdisciplinary approach, incorporating psychology, neuroscience, immunology, physiology, genetics, pharmacology, molecular biology, psychiatry, behavioral medicine, infectious diseases, endocrinology, and rheumatology.The main interests of PNI are the interactions between the nervous and immune systems and the relationships between mental processes and health. PNI studies, among other things, the physiological functioning of the neuroimmune system in health and disease; disorders of the neuroimmune system (autoimmune diseases; hypersensitivities; immune deficiency); and the physical, chemical and physiological characteristics of the components of the neuroimmune system in vitro, in situ, and in vivo.