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An Introduction to Vaccine Science and Basic Immunology
An Introduction to Vaccine Science and Basic Immunology

Cell Mediated Immunity 2016-20172016-10-24 08
Cell Mediated Immunity 2016-20172016-10-24 08

... Objectives • To describe antigen recognition by T cells • To describe the pathways involved in processing endogenous and exogenous antigens • To discuss self MHC restriction in Ag presentation to T cells • To describe the induction of cell meditated immunity (Chronic Inflammation) ...
General Defence System - leavingcertbiology.net
General Defence System - leavingcertbiology.net

... and set up an immune reaction where a massive response to the invader is carried out • Antibodies are produced by white blood cells which attach to invader. Other white blood cells then recognise that antibody that is attached to invader (i.e. the invader has been tagged for destruction) and phagocy ...
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... Monocytes are large immature forms of a macrophage … Chemical Mediators of Inflammation - http://web.indstate.edu/nurs/mary/PATHOPHY.htm Histamine: In response to injury, granulated leukocytes known as mast cells (fixed in the body organs) and basophils (flowing in blood stream) release histamine wh ...
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Bibliographic Vision on Plant Immunity Primary Immune System
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... (comprising lipid A, a core oligosaccharide, and an O-polysaccharide chain), which are important mediators of bacterial virulence and can elicit strong immune responses. Other Gram-negative bacteria are nonencapsulated and/or do not present O-antigen-containing lipopolysaccharides. This is the case ...
Immune response to biomateials rev 1
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... Antigen presentation with class II MHC activates Th lymphocytes by promoting binding of the antigen to the T cell receptor. Tc cells and B cells can also bind the antigen depending on how it is presented. Cytokines released by Th cells aid in activation of Tc cells after antigen binding. Co-stimula ...
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... e. What is immunocompetence? f. Which cells are most important in the development of immunocompetence? 2. Contrast the terms in the following pairs: (14 pts) a. innate and acquired immunity b. humoral and cell-mediated immunity c. active and passive immunity d. TH1 and TH2 cells e. natural and artif ...
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... Bacterial endotoxins Immune complexes Products of T-lymphocytes (adaptive immune response) ...
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... – Local dermal injury due to inflamed blood vessels in the vicinity of any injected antigen ...
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... BOX 12-1 Toll-like Receptors The Toll-like receptors (TLRs) are a family of membrane proteins that serve as pattern recognition receptors for a variety of microbe-derived molecules and stimulate innate immune responses to the microbes expressing these molecules. The first protein to be identified i ...
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... 2- Compensatory " when part of tissue removed or diseased like in liver partial resection, and connective tissue cells in wound healing, the neighboring healthy cells proliferate and increased in number . B- Pathological hyperplasia: Its mainly due to hormonal access or growth factor stimuli.  Endo ...
20.380 S10 Introduction: the Immune System– the basics, inflammation in health
20.380 S10 Introduction: the Immune System– the basics, inflammation in health

... endothelium. Leukocytes rolling on the endothelium in a selectin-mediated process are brought into contact with chemokines retained on cell-surface heparan sulfate proteoglycans. Chemokine signaling activates leukocyte integrins, leading to firm adherence and extravasation. The recruited leukocytes ...
Course of Immunology
Course of Immunology

... [email protected] ...
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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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