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ppt
ppt

... Instead of directly killing the worms these physiologial changes appear to render the intestine inhospitable for the parasite Increase in number of goblet cells (these are the cells in the intestinal epithelium which produce mucus - strong red stain in the histology image) Increase in mucin secretio ...
antigen processing and presentation
antigen processing and presentation

... The humoral immunity can be dependent or independent on T cell function. Most immune responses require the interaction of several cells, in a specific, sequential manner. Antigen-presenting cells (APCs) present Ag to helper T (TH) cells, specific activation and maturation signals are delivered by TH ...
cells
cells

... transmits activation signal 1 to the anti-id B cell. The fully activated anti-idiotypic B cell undergoes clonal expansion and secretes anti-id .This will form immune complex with circulation id which will be removed by phagocytes. Anti-id will also bind to id (BCR) on the surface of B cells. This wi ...
Transfer Factor - ILMU KESIHATAN Weblog
Transfer Factor - ILMU KESIHATAN Weblog

... much higher number of fat cells. Both types of bone marrow contain numerous blood vessels and capillaries. • The bone marrow is the location where all cells of the immune system begin their development from primitive stem cells. ...
幻灯片 1
幻灯片 1

... TI-1 antigen: also named B cell mitogen 1. Contains B cell mitogen and repeated B epitopes 2. Can induce immature and mature B cell-mediate immune response 3. In high concentrations, can induce polyclonal B-cell activation 4. In lower concentrations, only the BCR-binding TI-1 antigens can activate ...
White Blood Cells (WBCs)
White Blood Cells (WBCs)

... • there, they express specific T cell receptors and meet cells that “wear” bits of self proteins, called MHC (major histocompatibility complex), that are markers for the body’s own cells • there are two steps - first, T cells must recognize self-MHC, or they are destroyed - in a second step, T cells ...
Kuby Immunology 6/e - Dr. Jennifer Capers
Kuby Immunology 6/e - Dr. Jennifer Capers

TOPIC: Immunity AIM: What is immunity?
TOPIC: Immunity AIM: What is immunity?

Immune System
Immune System

... a.) There are three different types of immunity your body can take advantage of to fight disease: Innate, Acquired/Adaptive, and Passive. Innate immunity relates to the natural defenses of the human body, which includes barriers that keep harmful material out of your body. Acquired, or adaptive rela ...
CD40-Ligation in Vivo Promotes Activation and Migration of
CD40-Ligation in Vivo Promotes Activation and Migration of

... Adaptive immune responses begin after antigen bearing dendritic cells (DCs) traffic from peripheral tissues to lymph nodes where they play a key role in the initiation of specific T-cell responses. Ligation of CD40 is known to be an important signal in the activation and migration of Langerhans cell ...
BOSY_DEFENCE__ARISTO_
BOSY_DEFENCE__ARISTO_

... – skin arterioles in the infected area dilates so that more blood flows to the area – the permeability of skin capillaries increases so that more phagocytes & fluid come into the infected tissues – the skin becomes red & swell up with pain (because of high pressure) ...
Regulation of the complement system
Regulation of the complement system

Transport and cardiovascular systems
Transport and cardiovascular systems

... a. a gene that increases cell proliferation. b. a gene which codes a fluorescent protein. c. a gene important for repairing DNA damage. d. a gene that enables adaptation to hypoxia (low oxygen). e. a gene that stimulates angiogenesis (formation of new blood vessels). The acquired immune system is ve ...
Care of Patients with Immune Disorders
Care of Patients with Immune Disorders

... Passive Acquired Immunity – is temporary immunity transmitted from a source outside the body that has developed immunity through previous disease or immunization. Example: immune globulin or antiserum obtained from the blood plasma of people with acquired immunity is used in emergencies to provide i ...
DIET AND THE IMMUNE SYSTEM Professor Parveen Yaqoob 2010
DIET AND THE IMMUNE SYSTEM Professor Parveen Yaqoob 2010

... 9. Self-regulation is important because the immune system needs to know that it must stop when it has destroyed each foreign body and not continue otherwise it can cause damage to our own bodies. 10. The CD4 T cells are found in the blood and are important because they stop the HIV virus particles ...
PowerPoint ****
PowerPoint ****

... most of the same molecules, except that the TCR recognizes peptide–class I MHC complexes, and the coreceptor is CD8, which recognizes class I MHC. Immunoreceptor tyrosine-based activation motifs (ITAMs) are the regions of signaling proteins that are phosphorylated on tyrosine residues and become doc ...
1. The Cell-Mediated Immune Response
1. The Cell-Mediated Immune Response

... a J chain & a secretory component • present in saliva, mucus, breast milk & other secretions, is especially “tough”, and is the most abundant of all Ab’s ...
Chapter 11 Immune response(Ir)
Chapter 11 Immune response(Ir)

... • The first antibodies produced in a humoral immune response are IgM, but activated B cells subsequently undergo isotype switching or class switching to secrete antibodies of different isotypes: IgG, IgA, and IgE. Isotype switching does not affect antibody specificity significantly. ...
Presentation Title Here Presentation Subtitle Here
Presentation Title Here Presentation Subtitle Here

... TB Immunopathogenesis The Achilles heel • Increased susceptibility to TB with: ...
The Immune Response
The Immune Response

... As phagocytic cells with antigen nonspecific activity, they help to contain infectious agents until specific immunity can be marshaled. In addition, early in the host response, the macrophage functions as an accessory cell to ensure amplification of the inflammatory response and initiation of specif ...
AIDS and its Effect on the Immune Response
AIDS and its Effect on the Immune Response

... AIDS and its Effect on the Immune Response Acquired Immune Deficiency Syndrome (AIDS) is a disease that results in the destruction of an individual’s immune system. The virus that causes AIDS is passed from an infected individual to another person by means of body fluids such as blood, semen, or vag ...
N - C-CAMP
N - C-CAMP

... normal tissue, but reducing the tumour cell killing. • Since normal tissues are characterized by different a and b values, conditions can be found in which the sparing of normal tissue exceeds the reduction of tumour cells killing. • Therefore, higher total doses can be delivered, obtaining an ultim ...
Cancers of the Immune System
Cancers of the Immune System

... Cancer happens when cells grow out of control. This can also happen with the cells of the immune system. Leukemia, which involves abnormal overgrowth of leukocytes, is the most common childhood cancer. Lymphoma involves the lymphoid tissues and is also one of the more common childhood cancers. With ...
Biocompatibility
Biocompatibility

... • Lymphocyte- small cell in blood- recirculates through tissues and back through lymph --polices body for non-self material-- recognizes antigens through surface receptors • Antigen- produces antibody- stimulate adaptive immune response • Antibody- Serum globulins with wide range of specificity for ...
PLoS Pathog
PLoS Pathog

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Innate immune system



The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑
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