Vaccine developments
... There are several diseases for which there are currently no vaccines, including HIV, malaria and TB. To develop vaccines for these diseases new strategies inducing the cellular and humoral arms of the immune system may need to be employed. ...
... There are several diseases for which there are currently no vaccines, including HIV, malaria and TB. To develop vaccines for these diseases new strategies inducing the cellular and humoral arms of the immune system may need to be employed. ...
"Immunity to Infection". In: Encyclopedia of Life Sciences (ELS)
... the acute-phase response and fever. The acute-phase response is initiated when IL-1, IL-6 and TNFa reach hepatocytes. The liver increases the secretion of acute phase proteins into the blood plasma and suppresses the secretion of other plasma proteins. C-reactive protein and mannosebinding protein a ...
... the acute-phase response and fever. The acute-phase response is initiated when IL-1, IL-6 and TNFa reach hepatocytes. The liver increases the secretion of acute phase proteins into the blood plasma and suppresses the secretion of other plasma proteins. C-reactive protein and mannosebinding protein a ...
PrakashBaligar Assistant Professor Specialization: Stem Cell
... years in National Institute of Immunology (NII), New Delhi. Dr. Prakash joined Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR) as Assistant Professor in 2015, and his research focus is on Stem Cell and Tissue Engineering. Dr. Prakash flags the major concerns in transplantation ...
... years in National Institute of Immunology (NII), New Delhi. Dr. Prakash joined Amity Institute of Molecular Medicine and Stem Cell Research (AIMMSCR) as Assistant Professor in 2015, and his research focus is on Stem Cell and Tissue Engineering. Dr. Prakash flags the major concerns in transplantation ...
Cytokines and Chemokines
... complement associated with antigen play a role in antigen-induced B-cell activation. ...
... complement associated with antigen play a role in antigen-induced B-cell activation. ...
Lymphoid Tissues and Organs:
... 2-Bone marrow: -B lymphocytes are “home schooled” within this organs. -Function: Primary differentiation of B lymphocytes. B lymphocytes begin to display IgM on their surfaces. -The primary site for cytokines-Immune cell interactions. -Bone marrow removes the B cells that show selfreactivity by apop ...
... 2-Bone marrow: -B lymphocytes are “home schooled” within this organs. -Function: Primary differentiation of B lymphocytes. B lymphocytes begin to display IgM on their surfaces. -The primary site for cytokines-Immune cell interactions. -Bone marrow removes the B cells that show selfreactivity by apop ...
Dendritic cell
... Dendritic cells Naive lymphocytes: migrate through body Effector and memory lymphocytes: circulate in the blood ...
... Dendritic cells Naive lymphocytes: migrate through body Effector and memory lymphocytes: circulate in the blood ...
nature angiogenic awakening 8-2
... authors injected the tumour cells into zebrafish that were genetically engineered to have excessive microvascular sprouting, they observed enhanced proliferation of the cells adjacent to new blood-vessel tips. Angiogenesis — the growth of new blood vessels — is crucial to the ability of tumours and ...
... authors injected the tumour cells into zebrafish that were genetically engineered to have excessive microvascular sprouting, they observed enhanced proliferation of the cells adjacent to new blood-vessel tips. Angiogenesis — the growth of new blood vessels — is crucial to the ability of tumours and ...
Our Behind the Scenes Partner:
... Infants have an immature IgA system, hence infections with agents like RSV and Rotavirus ...
... Infants have an immature IgA system, hence infections with agents like RSV and Rotavirus ...
Immunogenetics
... recognize molecules in the body that don’t belong there. Foreign molecules (often on the surface of foreign organisms) raise an immune response in the body. The primary defense is a set of antibody molecules (also called immunoglobulins, Ig). The human body produces over 1,000,000 different antibodi ...
... recognize molecules in the body that don’t belong there. Foreign molecules (often on the surface of foreign organisms) raise an immune response in the body. The primary defense is a set of antibody molecules (also called immunoglobulins, Ig). The human body produces over 1,000,000 different antibodi ...
Immunogenetics
... recognize molecules in the body that don’t belong there. Foreign molecules (often on the surface of foreign organisms) raise an immune response in the body. The primary defense is a set of antibody molecules (also called immunoglobulins, Ig). The human body produces over 1,000,000 different antibodi ...
... recognize molecules in the body that don’t belong there. Foreign molecules (often on the surface of foreign organisms) raise an immune response in the body. The primary defense is a set of antibody molecules (also called immunoglobulins, Ig). The human body produces over 1,000,000 different antibodi ...
Janeway`s Immunology - Cal State LA
... Release granules upon receptor cross-linking Role in defense against parasites, allergy ...
... Release granules upon receptor cross-linking Role in defense against parasites, allergy ...
Is Nutrition Really Important?
... cells no longer have the nutritional reserves to protect and repair themselves they become sick and then replicate in a sick or diseased state. Eventually the cell can mutate into a cancerous cell. Normally a body with plenty of nutrition will have cells that can repair themselves or they will self- ...
... cells no longer have the nutritional reserves to protect and repair themselves they become sick and then replicate in a sick or diseased state. Eventually the cell can mutate into a cancerous cell. Normally a body with plenty of nutrition will have cells that can repair themselves or they will self- ...
commentaries
... significantly less live bacteria were recovered from the liver, and more were found in the blood, spleen, and lung in Vsig4-deficient mice. This defect in clearance of circulating bacteria by Vsig4-expressing liver Kupffer cells resulted in increased levels of serum cytokines, and these mice suffere ...
... significantly less live bacteria were recovered from the liver, and more were found in the blood, spleen, and lung in Vsig4-deficient mice. This defect in clearance of circulating bacteria by Vsig4-expressing liver Kupffer cells resulted in increased levels of serum cytokines, and these mice suffere ...
56. Novel immunological approaches for emergency FMD vaccines
... Europe. Due to the rapidity of FMDV replication and spread, the development of vaccine formulations inducing early protection is critical for an emergency scenario. Our strategy is to stimulate innate antiviral immune defence by targeting natural interferon producing cells (NIPC). One possibility ar ...
... Europe. Due to the rapidity of FMDV replication and spread, the development of vaccine formulations inducing early protection is critical for an emergency scenario. Our strategy is to stimulate innate antiviral immune defence by targeting natural interferon producing cells (NIPC). One possibility ar ...
Blood
... – Oxygen loading takes place in the lungs • Deoxyhemoglobin – hemoglobin after oxygen diffuses into tissues (reduced Hb) • Carbaminohemoglobin – hemoglobin bound to carbon dioxide – Carbon dioxide loading takes place in the tissues ...
... – Oxygen loading takes place in the lungs • Deoxyhemoglobin – hemoglobin after oxygen diffuses into tissues (reduced Hb) • Carbaminohemoglobin – hemoglobin bound to carbon dioxide – Carbon dioxide loading takes place in the tissues ...
Lymph Nodes
... • T cells and B cells protect against antigens – Anything body perceives as foreign • Bacteria and bacterial toxins, viruses, mismatched RBCs, cancer cells ...
... • T cells and B cells protect against antigens – Anything body perceives as foreign • Bacteria and bacterial toxins, viruses, mismatched RBCs, cancer cells ...
Abstract:
... CD28 superagonist antibody treatment mediated expansion of IL-10 producing Tregs, down-regulated IFN-γ production by T cells as well as TNF-α production by M1 cells, triggered the development of alternatively activated monocytic cells (M2), delayed the onset of liver injury, diminished the anemia bu ...
... CD28 superagonist antibody treatment mediated expansion of IL-10 producing Tregs, down-regulated IFN-γ production by T cells as well as TNF-α production by M1 cells, triggered the development of alternatively activated monocytic cells (M2), delayed the onset of liver injury, diminished the anemia bu ...
Bacterial strategies for overcoming host innate and adaptive
... respond specifically through the identification of conserved components of these microbes. These microbial structures are termed pathogen-associated molecular patterns (PAMPs) and include parts of the bacterial cell envelope, such as lipopolysaccharide (LPS), peptidoglycan and bacterial DNA. Recogni ...
... respond specifically through the identification of conserved components of these microbes. These microbial structures are termed pathogen-associated molecular patterns (PAMPs) and include parts of the bacterial cell envelope, such as lipopolysaccharide (LPS), peptidoglycan and bacterial DNA. Recogni ...
New weapons in the fight against HIV
... a molecular fingerprint for immune cells to recognise. However, HIV can rapidly change this fingerprint once an immune response is mounted against it, allowing the virus to stay one step ahead of our killer T-cell response. Professor Sewell’s team redesigned the receptor molecule that recognises SL9 ...
... a molecular fingerprint for immune cells to recognise. However, HIV can rapidly change this fingerprint once an immune response is mounted against it, allowing the virus to stay one step ahead of our killer T-cell response. Professor Sewell’s team redesigned the receptor molecule that recognises SL9 ...
Company Fact Sheet
... After an HSCT treatment, patients are highly susceptible and vulnerable to infections. Immune cells in ATIRTM will help fight these opportunistic infections and bridge the time until the immune system has fully re-grown from stem cells in the transplanted graft. ATIRTM products (see development stat ...
... After an HSCT treatment, patients are highly susceptible and vulnerable to infections. Immune cells in ATIRTM will help fight these opportunistic infections and bridge the time until the immune system has fully re-grown from stem cells in the transplanted graft. ATIRTM products (see development stat ...
Innate immune system
The innate immune system, also known as the nonspecific immune system, is an important subsystem of the overall immune system that comprises the cells and mechanisms that defend the host from infection by other organisms. The cells of the innate system recognize and respond to pathogens in a generic way, but, unlike the adaptive immune system (which is found only in vertebrates), it does not confer long-lasting or protective immunity to the host. Innate immune systems provide immediate defense against infection, and are found in all classes of plant and animal life. They include both humoral immunity components and cell-mediated immunity components.The innate immune system is an evolutionarily older defense strategy, and is the dominant immune system found in plants, fungi, insects, and primitive multicellular organisms.The major functions of the vertebrate innate immune system include: Recruiting immune cells to sites of infection, through the production of chemical factors, including specialized chemical mediators, called cytokines Activation of the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells The identification and removal of foreign substances present in organs, tissues, the blood and lymph, by specialised white blood cells Activation of the adaptive immune system through a process known as antigen presentation Acting as a physical and chemical barrier to infectious agents.↑ ↑ ↑