Butyrate and Mucosal Inflammation: New Scientific
... fermentation of dietary fibers. Luminal SCFAs are recognized as a preferred energy substrate for the colonic epithelium. As early as the 1980s, SCFAs were observed to offer therapeutic benefit in some forms of colitis.1 Since then, clinical trials have produced variable results in confirming the eff ...
... fermentation of dietary fibers. Luminal SCFAs are recognized as a preferred energy substrate for the colonic epithelium. As early as the 1980s, SCFAs were observed to offer therapeutic benefit in some forms of colitis.1 Since then, clinical trials have produced variable results in confirming the eff ...
Regional Specialisation of T Cell Subsets and Apoptosis in the
... The mucosal immune system of the healthy intestine has to maintain the balance between tolerogenic and pro-inflammatory immune responses. Each region of the intestine has unique characteristics related to specific functions and differential predominant antigens.1 The small bowel has to deal with a h ...
... The mucosal immune system of the healthy intestine has to maintain the balance between tolerogenic and pro-inflammatory immune responses. Each region of the intestine has unique characteristics related to specific functions and differential predominant antigens.1 The small bowel has to deal with a h ...
Colonic microbiota can promote rapid local improvement of
... there is an inverse association between cumulative dose and leucocyte counts, consistent with the clinical experience with these immunomodulatory drugs in IBD. Thus, total mesenteric lymph node (MLN) cell numbers expectedly increased with DSS treatment in association with the DSS-induced colitis in ...
... there is an inverse association between cumulative dose and leucocyte counts, consistent with the clinical experience with these immunomodulatory drugs in IBD. Thus, total mesenteric lymph node (MLN) cell numbers expectedly increased with DSS treatment in association with the DSS-induced colitis in ...
The Lung Immunology Group Department of Biological Sciences
... NK cell activation • A tug-of-war between between activatory and inhibitory ligand-receptor interactions between NK cell and target cell • Several such pairings - one group is the interaction between HLA-C molecules and KIRs (killer immunoglobulin-like receptors) • Different HLA-C alleles interact ...
... NK cell activation • A tug-of-war between between activatory and inhibitory ligand-receptor interactions between NK cell and target cell • Several such pairings - one group is the interaction between HLA-C molecules and KIRs (killer immunoglobulin-like receptors) • Different HLA-C alleles interact ...
Mechanisms of Disease: the hygiene hypothesis revisited
... The incidence of allergic disorders in the US and Europe has increased since the late nineteenth century, and seems to have doubled in some decades, particularly during the 1960s and 1970s.1 A link between the increasing incidence of allergies and the modern hygienic lifestyle was initially suggeste ...
... The incidence of allergic disorders in the US and Europe has increased since the late nineteenth century, and seems to have doubled in some decades, particularly during the 1960s and 1970s.1 A link between the increasing incidence of allergies and the modern hygienic lifestyle was initially suggeste ...
Diverticular disease
... diverticular disease can mimic other more serious conditions such as bowel cancer. If any of these symptoms are noticed or a change in the symptoms occur, do not assume it is due to diverticular disease and see a doctor who may suggest further investigations. How is diverticular disease diagnosed? D ...
... diverticular disease can mimic other more serious conditions such as bowel cancer. If any of these symptoms are noticed or a change in the symptoms occur, do not assume it is due to diverticular disease and see a doctor who may suggest further investigations. How is diverticular disease diagnosed? D ...
Nursing Care of the Adult with Rheumatic Disorders
... Treatment Goals/SLE Prevent flares Treat flares when they occur Minimize complications/loss of organ function Minimize disabilities/improve functional status Prevent complications from therapy/treatment Promote self management Manage psychological implications ...
... Treatment Goals/SLE Prevent flares Treat flares when they occur Minimize complications/loss of organ function Minimize disabilities/improve functional status Prevent complications from therapy/treatment Promote self management Manage psychological implications ...
Chapter 13
... Alveolar macrophages represent the majority of free cells within the alveolar spaces. These cells are functionally distinct from macrophages in most other tissues in that they maintain an anti-inflammatory phenotype. They express IL-10, nitric oxide, and TGF-β and are poorly phagocytic compared with ...
... Alveolar macrophages represent the majority of free cells within the alveolar spaces. These cells are functionally distinct from macrophages in most other tissues in that they maintain an anti-inflammatory phenotype. They express IL-10, nitric oxide, and TGF-β and are poorly phagocytic compared with ...
Inflammatory bowel disease
Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the colon and small intestine. Crohn's disease and ulcerative colitis are the principal types of inflammatory bowel disease. It is important to note that not only does Crohn's disease affect the small intestine and large intestine, it can also affect the mouth, esophagus, stomach and the anus whereas ulcerative colitis primarily affects the colon and the rectum.Inflammatory bowel diseases resulted in 51,000 deaths in 2013 and 55,000 deaths in 1990.