![Seroquel - Medsafe](http://s1.studyres.com/store/data/007077754_1-55f32deafd74fe194b218b86462acd68-300x300.png)
Seroquel - Medsafe
... Patients who have responded to SEROQUEL in combination therapy with a mood stabiliser for acute treatment of bipolar disorder should continue on SEROQUEL therapy at the same dose. The SEROQUEL dose can be re-adjusted depending on clinical response and tolerability of the individual patient. Efficacy ...
... Patients who have responded to SEROQUEL in combination therapy with a mood stabiliser for acute treatment of bipolar disorder should continue on SEROQUEL therapy at the same dose. The SEROQUEL dose can be re-adjusted depending on clinical response and tolerability of the individual patient. Efficacy ...
Corticosteroids for the treatment of idiopathic acute
... features such as nausea and vomiting are often present. Audiometry (hearing tests) and brain imaging are normal in the condition. Specific tests of vestibular function (electronystagmography and caloric testing) can document the unilateral loss of vestibular function but they are rarely necessary (B ...
... features such as nausea and vomiting are often present. Audiometry (hearing tests) and brain imaging are normal in the condition. Specific tests of vestibular function (electronystagmography and caloric testing) can document the unilateral loss of vestibular function but they are rarely necessary (B ...
OE05 Protocol - MRC Clinical Trials Unit
... of morbidity and mortality. Significant complications have been observed in 30-50% of patients and post-operative mortality rates vary between 7% and 15%. After much discussion, the trial management group have decided that in the light of these findings, further modification is required to ensure sa ...
... of morbidity and mortality. Significant complications have been observed in 30-50% of patients and post-operative mortality rates vary between 7% and 15%. After much discussion, the trial management group have decided that in the light of these findings, further modification is required to ensure sa ...
core_defects_of_type_2_diabetes_part_ 4_of_4
... • Cardiovascular collapse (shock) from whatever cause, acute congestive heart failure, acute myocardial infarction and other conditions characterized by hypoxemia have been associated with lactic acidosis and may also cause prerenal azotemia. When such events occur in patients on JANUMET therapy, th ...
... • Cardiovascular collapse (shock) from whatever cause, acute congestive heart failure, acute myocardial infarction and other conditions characterized by hypoxemia have been associated with lactic acidosis and may also cause prerenal azotemia. When such events occur in patients on JANUMET therapy, th ...
Antiemetics for reducing vomiting related to acute gastroenteritis in
... comprehensive electronic database searches and hand searches of relevant journals and abstract books of conferences.The search was re-run and is up to date as on 20 July 2010. Selection criteria Randomized controlled trials comparing antiemetics with placebo or no treatment, in children and adolesce ...
... comprehensive electronic database searches and hand searches of relevant journals and abstract books of conferences.The search was re-run and is up to date as on 20 July 2010. Selection criteria Randomized controlled trials comparing antiemetics with placebo or no treatment, in children and adolesce ...
regular lecture/teaching programs
... Large Clinical Trial Annals of Allergy , Asthma, and Immunology 2003;90:127 Chipps, B., Kim, K., Korenblat, P., Deniz, Y., Zheng, B., Carroll, A., Effect of Omalizumab on Health Care Utilization in Patients with Moderate to Moderate to Severe Allergic Asthma. Journal of Allergy & Clinical Immunology ...
... Large Clinical Trial Annals of Allergy , Asthma, and Immunology 2003;90:127 Chipps, B., Kim, K., Korenblat, P., Deniz, Y., Zheng, B., Carroll, A., Effect of Omalizumab on Health Care Utilization in Patients with Moderate to Moderate to Severe Allergic Asthma. Journal of Allergy & Clinical Immunology ...
FULL PRESCRIBING INFORMATION: CONTENTS*
... including Raynaud’s phenomenon. Signs and symptoms are usually intermittent and mild; however, very rare sequelae include digital ulceration and/or soft tissue breakdown. Effects of peripheral vasculopathy, including Raynaud’s phenomenon, were observed in post-marketing reports at different times an ...
... including Raynaud’s phenomenon. Signs and symptoms are usually intermittent and mild; however, very rare sequelae include digital ulceration and/or soft tissue breakdown. Effects of peripheral vasculopathy, including Raynaud’s phenomenon, were observed in post-marketing reports at different times an ...
Prescribing Information
... Raynaud’s phenomenon. Signs and symptoms are usually intermittent and mild; however, very rare sequelae include digital ulceration and/or soft tissue breakdown. Effects of peripheral vasculopathy, including Raynaud’s phenomenon, were observed in post-marketing reports at different times and at thera ...
... Raynaud’s phenomenon. Signs and symptoms are usually intermittent and mild; however, very rare sequelae include digital ulceration and/or soft tissue breakdown. Effects of peripheral vasculopathy, including Raynaud’s phenomenon, were observed in post-marketing reports at different times and at thera ...
STRATOS 1 and 2: considerations in clinical trial design for a fully
... symptom score (total, daytime and nighttime); standardized asthma quality of life questionnaire (AQLQ[S]) for ≥12 years [48] ; and ACQ-6 [49,50] . In order to demonstrate increased asthma symptom control compared with placebo, tralokinumab needs to show a significant effect on the percentage change ...
... symptom score (total, daytime and nighttime); standardized asthma quality of life questionnaire (AQLQ[S]) for ≥12 years [48] ; and ACQ-6 [49,50] . In order to demonstrate increased asthma symptom control compared with placebo, tralokinumab needs to show a significant effect on the percentage change ...
Goals of asthma treatment: how high should we go? EDITORIAL H.K. Reddel
... of asthma control. For example, if in one 8-week assessment a subject woke every night because of asthma and used reliever medication many times per day, but in the next 8 weeks experienced only 6 days of mild symptoms requiring reliever medication, asthma would be categorised as "Uncontrolled" in b ...
... of asthma control. For example, if in one 8-week assessment a subject woke every night because of asthma and used reliever medication many times per day, but in the next 8 weeks experienced only 6 days of mild symptoms requiring reliever medication, asthma would be categorised as "Uncontrolled" in b ...
Tacrolimus vs. Azathioprine in myasthenia gravis treatment. A multicenter, prospective, randomized, double
... weeks after the administration (17). Ponseti et al. (16) concluded in their article that 9/13 patients evaluated achieved pharmacological remission (no symptoms during one year, except ocular fatigability) during the first month of treatment and all patients reached the endpoint at 12 months; other ...
... weeks after the administration (17). Ponseti et al. (16) concluded in their article that 9/13 patients evaluated achieved pharmacological remission (no symptoms during one year, except ocular fatigability) during the first month of treatment and all patients reached the endpoint at 12 months; other ...
Industry-sponsored clinical drug trials in Egypt: Ethical
... made adequate provisions for post-trial treatment access for participants in Egypt. Finally, this report’s findings and conclusions justify an increase of inspections of clinical trials in Egypt by European Regulatory Authorities. Egyptian authorities should develop a single, robust legislative fram ...
... made adequate provisions for post-trial treatment access for participants in Egypt. Finally, this report’s findings and conclusions justify an increase of inspections of clinical trials in Egypt by European Regulatory Authorities. Egyptian authorities should develop a single, robust legislative fram ...
Scientific Research in Homeopathy
... Pollens in 30c potency for hay fever (1986) Is evidence for homoeopathy reproducible? (1994) //homeopathic medicine in 30c on 28 allergic asthma patients does more than placebo 2. International Journal of Oncology Ruta 6 induces cell deaths in brain cancer cells: A novel treatment for human brain ca ...
... Pollens in 30c potency for hay fever (1986) Is evidence for homoeopathy reproducible? (1994) //homeopathic medicine in 30c on 28 allergic asthma patients does more than placebo 2. International Journal of Oncology Ruta 6 induces cell deaths in brain cancer cells: A novel treatment for human brain ca ...
Near/far matching-- a study design approach to instrumental variables
... In analogy to the RCT, at the outset of the analysis, it is advisable for the analyst performing a near/far matching to blind him/herself to three kinds of variables to ensure the information is not used in the matching procedure outlined below. The first variable is the outcome of interest. The sec ...
... In analogy to the RCT, at the outset of the analysis, it is advisable for the analyst performing a near/far matching to blind him/herself to three kinds of variables to ensure the information is not used in the matching procedure outlined below. The first variable is the outcome of interest. The sec ...
A Control Model to Evaluate Pharmacotherapy for Allergic Rhinitis in
... to asthma risk as measured by lung function tests and asthma symptom scores.30-32 A study30 of schoolchildren with moderate to severe PAR and no history of asthma found that approximately 25% had abnormal lung function as evidenced by a forced expiratory flow between 25% and 75% of vital capacity of ...
... to asthma risk as measured by lung function tests and asthma symptom scores.30-32 A study30 of schoolchildren with moderate to severe PAR and no history of asthma found that approximately 25% had abnormal lung function as evidenced by a forced expiratory flow between 25% and 75% of vital capacity of ...
Opioids compared to placebo or other treatments for chronic low
... of women. Most of the trials followed the patients during three months and were supported by the pharmaceutical industry. Key results In general, people that received opioids reported more pain relief and had less difficulty performing their daily activities in the shortterm than those who received ...
... of women. Most of the trials followed the patients during three months and were supported by the pharmaceutical industry. Key results In general, people that received opioids reported more pain relief and had less difficulty performing their daily activities in the shortterm than those who received ...
Headache - New York Headache Center
... Migraine Diagnosis Migraine is under-diagnosed 94% of patients presenting to a PCP with recurrent headache met IHS criteria for migraine or probable migraine Nearly 90% of “sinus headache” patients met IHS criteria for migraine or probable migraine Nearly 90% of “tension/stress” headache patient ...
... Migraine Diagnosis Migraine is under-diagnosed 94% of patients presenting to a PCP with recurrent headache met IHS criteria for migraine or probable migraine Nearly 90% of “sinus headache” patients met IHS criteria for migraine or probable migraine Nearly 90% of “tension/stress” headache patient ...
Original article
... specifically. Most of the budget is targeted at infectious diseases due to associated morbidity and mortality with such diseases. Therefore, the patients needing publically – funded orthodontic treatment need to be screened properly for proper utilization of funds. DAI has been proved in previous st ...
... specifically. Most of the budget is targeted at infectious diseases due to associated morbidity and mortality with such diseases. Therefore, the patients needing publically – funded orthodontic treatment need to be screened properly for proper utilization of funds. DAI has been proved in previous st ...
product monograph zyban
... The third study was a long-term relapse prevention trial conducted at five clinical centers. Patients in this study received open-label ZYBAN 300mg/day for 7 weeks. Patients who quit smoking while receiving ZYBAN were then randomized to ZYBAN 300 mg/day or placebo for a total study duration of 1 yea ...
... The third study was a long-term relapse prevention trial conducted at five clinical centers. Patients in this study received open-label ZYBAN 300mg/day for 7 weeks. Patients who quit smoking while receiving ZYBAN were then randomized to ZYBAN 300 mg/day or placebo for a total study duration of 1 yea ...
long lasting β2 agonists
... Americans (of whom only 38% were using regular inhaled corticosteroids). In a review of three randomised placebo controlled studies evaluating effects of add-on formoterol, a dose higher than that currently recommended (24 μg twice daily) was associated with more frequent asthma exacerbations.12 How ...
... Americans (of whom only 38% were using regular inhaled corticosteroids). In a review of three randomised placebo controlled studies evaluating effects of add-on formoterol, a dose higher than that currently recommended (24 μg twice daily) was associated with more frequent asthma exacerbations.12 How ...
A. INGREDIENT NAME:
... 10 those of neostigmine (see p. 1I 17) but more prolonged. Maximum inhibition of plasma chohnes!crase occurs 9 hours after a smRle intramuscular dose. and persists for about 24 hours. [t is used in the prevention and treatment of postoperative imes!inal arony and urinary rccenhom 500 vg of dis[igmme ...
... 10 those of neostigmine (see p. 1I 17) but more prolonged. Maximum inhibition of plasma chohnes!crase occurs 9 hours after a smRle intramuscular dose. and persists for about 24 hours. [t is used in the prevention and treatment of postoperative imes!inal arony and urinary rccenhom 500 vg of dis[igmme ...
Identifying Provider Prejudice in Healthcare
... higher benefits from treatment for minority patients. In contrast to this interpretation for why blacks and women (henceforth referred to as minorities) receive less care, membership in a minority group may predict lower benefit from treatment because of its statistical association with biology, pr ...
... higher benefits from treatment for minority patients. In contrast to this interpretation for why blacks and women (henceforth referred to as minorities) receive less care, membership in a minority group may predict lower benefit from treatment because of its statistical association with biology, pr ...
Peanut oral immunotherapy in adolescents: study protocol for a
... In an education session, the patients and their parents will learn how to recognize food allergy symptoms, to evaluate their severity, and to use the rescue medications and self-injectable epinephrine. A first DBPCOFC is managed according to national recommendations [12]. It consists in the intake o ...
... In an education session, the patients and their parents will learn how to recognize food allergy symptoms, to evaluate their severity, and to use the rescue medications and self-injectable epinephrine. A first DBPCOFC is managed according to national recommendations [12]. It consists in the intake o ...
Boehringer Ingelheim (Pty) Ltd, South Africa
... Prevention of Mother to Child Transmission(pMTCT) of HIV- Treatment Options Preservation Study (T.O.P.S.) Investigators: Multicentre Study centre(s) : South Africa Clinical phase : III Objectives: To determine whether a regimen of single dose nevirapine combined with either 4 or 7 days of Combivir®, ...
... Prevention of Mother to Child Transmission(pMTCT) of HIV- Treatment Options Preservation Study (T.O.P.S.) Investigators: Multicentre Study centre(s) : South Africa Clinical phase : III Objectives: To determine whether a regimen of single dose nevirapine combined with either 4 or 7 days of Combivir®, ...
Placebo-controlled study
![](https://commons.wikimedia.org/wiki/Special:FilePath/Cebocap.jpg?width=300)
Placebo-controlled studies are a way of testing a medical therapy in which, in addition to a group of subjects that receives the treatment to be evaluated, a separate control group receives a sham ""placebo"" treatment which is specifically designed to have no real effect. Placebos are most commonly used in blinded trials, where subjects do not know whether they are receiving real or placebo treatment. Often, there is also a further ""natural history"" group that does not receive any treatment at all.The purpose of the placebo group is to account for the placebo effect, that is, effects from treatment that do not depend on the treatment itself. Such factors include knowing one is receiving a treatment, attention from health care professionals, and the expectations of a treatment's effectiveness by those running the research study. Without a placebo group to compare against, it is not possible to know whether the treatment itself had any effect.Patients frequently show improvement even when given a sham or ""fake"" treatment. Such intentionally inert placebo treatments can take many forms, such as a pill containing only sugar, a surgery where nothing efficacious is actually done (just an incision and sometimes some minor touching or handling of the underlying structures), or a medical device (such as an ultrasound machine) that is not actually turned on. Also, due to the body's natural healing ability and statistical effects such as regression to the mean, many patients will get better even when given no treatment at all. Thus, the relevant question when assessing a treatment is not ""does the treatment work?"" but ""does the treatment work better than a placebo treatment, or no treatment at all?"" As one early clinical trial researcher wrote, ""the first object of a therapeutic trial is to discover whether the patients who receive the treatment under investigation are cured more rapidly, more completely or more frequently, than they would have been without it.""p.195 More broadly, the aim of a clinical trial is to determine what treatments, delivered in what circumstances, to which patients, in what conditions, are the most effective.Therefore, the use of placebos is a standard control component of most clinical trials, which attempt to make some sort of quantitative assessment of the efficacy of medicinal drugs or treatments. Such a test or clinical trial is called a placebo-controlled study, and its control is of the negative type. A study whose control is a previously tested treatment, rather than no treatment, is called a positive-control study, because its control is of the positive type.Government regulatory agencies approve new drugs only after tests establish not only that patients respond to them, but also that their effect is greater than that of a placebo (by way of affecting more patients, by affecting responders more strongly, or both). As a result, ""placebo-controlled studies often are designed in such a way that disadvantages the placebo condition"".