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boomsma intro boulder 2008 - Institute for Behavioral Genetics
boomsma intro boulder 2008 - Institute for Behavioral Genetics

... Identical genomes; differences caused by Environment? ...
Fri 1110 Jackson-Cook - Association of Genetic Technologists
Fri 1110 Jackson-Cook - Association of Genetic Technologists

... •Do most acquired chromosomal changes arise from environmental insults, or are they “programmed” to occur as a result of an individual’s genetic make-up? •Are chromosomes with longer or shorter telomeres involved more often in age-related chromosomal changes? •Can telomere lengths or acquired chromo ...
Bipolar Illness and Schizophrenia as Oligogenic Diseases
Bipolar Illness and Schizophrenia as Oligogenic Diseases

... modeled as the sum of effects of a very large number of individual genes with infinitesimal additive effects. This was termed polygenic inheritance, and it was not actually expected that the individual genetic components would ever be detectable. Later, it became apparent that a trait determined by ...
Genetics Study Guide (Chapter 5)
Genetics Study Guide (Chapter 5)

... 7. Be able to read a karyotype and determine what disease (if any) the child has and his or her gender. (there will be a chart of the diseases available) 8. What is a sex-linked disorder and how is it different from a regular trait or disorder? On which chromosome are the genes found? 9. Make a Punn ...
The value of twins and the importance of twin research
The value of twins and the importance of twin research

... much of this is due to them growing up in the same environment or because they share the same genes. Twin studies allow us to disentangle these effects, because of the unique nature of both types of twins. This is because twin studies take advantage of two sets of naturally occurring twins: identica ...
Exhibit D-Autism Genetics
Exhibit D-Autism Genetics

... Some children have a very abrupt onset to their symptoms after being apparently normal (“regressive autism”); others appear to be affected from birth, and symptoms emerge as the child gets older. ...
TWINS AND GENETICS
TWINS AND GENETICS

... >> population stratification: the general population contains several sub‐groups, and  allele A is more frequent in one of them.  HLA‐A1 is associated to the ability to eat with chopsticks in San Francisco  HLA A1 is more frequent in Chinese, who are a large sub group in San Francisco. ...
Document
Document

... • Because environments provided/created by parents depend on their genotype, environments will be generally matched to children’s genotype Evocative gene influences • Child’s heritable characteristics affect behavior of others towards child Active gene influences (niche picking) • Environments child ...
Changing Ideas of Normality and Abnormality Danish
Changing Ideas of Normality and Abnormality Danish

...  ‘epigenetics’: changes in cells during development, especially in gene regulation, that can be transmitted from one generation (of cells or organisms) to the next while not being encoded in the sequence of DNA bases in the genome. ...
Why do students find genetics so hard to learn?
Why do students find genetics so hard to learn?

... 6. Our teaching doesn’t adequately reflect the research slant, which gives context • E.g. “Mendelian Genetics” is often taught as a time capsule, whereas in research today this kind of genetics is really about gene discovery through mutational dissection. • E.g. Modified F2 ratios often taught as “ ...
To what extent would you argue that Stephen
To what extent would you argue that Stephen

... psychologist at the University of California at Santa Barbara, a child whose biological parents are criminals is more likely than other children to begin a criminal career himself even if his adopted parents are law abiding. Yet another Scandinavian adoption study, this time in Sweden, found a link ...
Slide 1
Slide 1

... Coronary artery disease ...
TWO TYPES OF TRAITS
TWO TYPES OF TRAITS

... If a trait, say height, is controlled by two loci, A and B, and each locus has two alleles, one regular and one prime allele, what are the possible genotypes ...
Mutational analysis of the connexin 36 gene (CX36)
Mutational analysis of the connexin 36 gene (CX36)

... with periodic catatonia express a variable phenotype combining akinetic negativism, hyperkinesia with stereotypies and parakinetic movements as well as increased anxiety, impulsivity and aggressiveness. Acute psychotic episodes may be accompanied by hallucinations and delusions, while successive epi ...
Unpacking Outcomes - NESD Curriculum Corner
Unpacking Outcomes - NESD Curriculum Corner

... Distinguish among patterns of inheritance (i.e., dominant and recessive alleles, sex-linked traits, co-dominance, incomplete dominance, and multiple alleles) of heritable traits. Determine an organism’s phenotype from its genotype, and where possible, its genotype from its phenotype. Construct Punne ...
Genetic Disease Graphic Organizer
Genetic Disease Graphic Organizer

... type of genetic disorder such as autosomal dominant, autosomal recessive; Xlinked, etc..; what are the possible genotypes of the parents; use a karyotype, punnett square or pedigree to illustrate the inheritance. ...
gene-environment interaction and twin studies
gene-environment interaction and twin studies

... not large. For the favorable case of the MN blood group with two alleles of high frequency, around 530 MZ twins would need to be typed for 80% power at the 5% significance level. 6 A forward-looking (and rich!) gene-hunting company would be obtaining good phenotypes on large numbers of MZ twins agai ...
PPT - Med Study Group
PPT - Med Study Group

... • Studies which compare a group of interest (cases) to a control group for the presence of a gene or SNP. • Controls are matched to cases for characteristics that may confound results: age, ethnicity, gender, environment. • If the SNP is present more often in cases than controls, it is associated wi ...
FYI
FYI

... How did the work of genetics get started? You may have heard of Gregor Mendel. He was a priest that experimented with pea plants. ...
Student/Faculty Research Day
Student/Faculty Research Day

... correlation between concordance rates for communication disorders in monozygotic and dizygotic twins. Both authors are twins which is what prompted interest in this topic. Factors determining concordance rates are genetics and shared and non-shared environments. Twin studies provide a natural experi ...
Chapter 16
Chapter 16

... developmental abnormality or a degenerative process that occurs early in life Repeated episodes of depression and mania caused an increase in the size of the lateral ventricles The amygdala and several regions of the prefrontal cortex play a role in the development of depression ...
Course Specification BIOL 338 – Genetics
Course Specification BIOL 338 – Genetics

... Knowledge and understanding: At the end of this course the students should be able to: K1- Define linkage and explain why linkage interferes with independent assortment. K2- Distinguish between parental and recombinant phenotypes. K3- Explain how crossing over can unlink genes. K4- Map a linear sequ ...
7.4 Human Genetics and Pedigrees TEKS 6F, 6H
7.4 Human Genetics and Pedigrees TEKS 6F, 6H

... 6F predict possible outcomes of various genetic combinations such as monohybrid crosses, dihybrid crosses and non Mendelian inheritance and 6H describe how techniques such as DNA fingerprinting, genetic modifications, and chromosomal analysis are used to study the genomes of organisms ...
Human Genetics
Human Genetics

... Regarding cardiovascular disease  Adoptive parents who died of cardiovascular disease before age 50, their adoptive children were 3 times more likely to die of cardiovascular disease than a person in the general population.  suggests a strong environmental component ...
PG25_71
PG25_71

... and His7, reported in (1), has not been affected by the chromosome rearrangement found in line WL1393. This line was a progenitor of the individual plant His(2-6)1323, A, Lf, His73 (selected from the F2 of the cross WL1393 x WL1688) which was used as the female parent, together with WL102 as the mal ...
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Irving Gottesman

Irving Isadore Gottesman (born December 29, 1930) is a professor of psychology who has devoted most of his career to the study of the genetics of schizophrenia. He has written 17 books and more than 290 other publications, mostly on schizophrenia and behavioral genetics, and created the first academic program on behavioral genetics in the United States. He has won awards such as the Hofheimer Prize for Research, the highest award from the American Psychiatric Association for psychiatric research. Gottesman is a professor in the psychology department at the University of Minnesota, where he received his Ph.D.A native of Ohio, Gottesman studied psychology for his undergraduate and graduate degrees, became a faculty member at various universities, and spent most of his career at the University of Virginia and the University of Minnesota. He is known for researching schizophrenia in identical twins to document the contributions of genetics and the family, social, cultural, and economic environment to the onset, progress, and inter-generational transmission of the disorder. Gottesman has worked with researchers to analyze hospital records and conduct follow-up interviews of twins where one or both were schizophrenic. He has also researched the effects of genetics and the environment on human violence and variations in human intelligence. Gottesman and co-researcher James Shields introduced the word epigenetics—the control of genes by biochemical signals modified by the environment from other parts of the genome—to the field of psychiatric genetics.Gottesman has written and co-written a series of books which summarize his work. These publications include raw data from various studies, their statistical interpretation, and possible conclusions presented with necessary background material. The books also include first-hand accounts of schizophrenic patients and relatives tending to them, giving an insight into jumbled thoughts, the disorder's primary symptom. Gottesman and Shields have built models to explain the cause, transmission, and progression of the disorder, which is controlled by many genes acting in concert with the environment, with no cause sufficient by itself.
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