Rapid Evolution in the Human Genome
... lineage-specific evolution: a phylogenetic hidden Markov model (phylo-HMM) and a likelihood ratio test (LRT). The phylo-HMM works well for identifying relatively ancient events, while the LRT is much more powerful at the leaves of a phylogeny (e.g. the human lineage). Using this LRT, we identified 2 ...
... lineage-specific evolution: a phylogenetic hidden Markov model (phylo-HMM) and a likelihood ratio test (LRT). The phylo-HMM works well for identifying relatively ancient events, while the LRT is much more powerful at the leaves of a phylogeny (e.g. the human lineage). Using this LRT, we identified 2 ...
statistical testing
... Starting in September 2009, this unit has contributed to different research projects by providing support and expertise in programming and advanced data analysis, focusing primarily on high-throughput genomics technologies including microarrays, genotyping and next-generation sequencing. The unit is ...
... Starting in September 2009, this unit has contributed to different research projects by providing support and expertise in programming and advanced data analysis, focusing primarily on high-throughput genomics technologies including microarrays, genotyping and next-generation sequencing. The unit is ...
Comparative Genomics Course
... organisms (microbes, flies, worms, Arabidopsis, etc.) this is a good opportunity to delve into the most relevant databases. The user interfaces are distinctive for each, although there are many general similarities. Please turn in a report about what you learned in your exploration. A page should be ...
... organisms (microbes, flies, worms, Arabidopsis, etc.) this is a good opportunity to delve into the most relevant databases. The user interfaces are distinctive for each, although there are many general similarities. Please turn in a report about what you learned in your exploration. A page should be ...
2014-09 ICGI Wuhan Research Conference
... Lee1, Ping Zheng1, Don Jones2, Richard Percy3, Dorrie Main1 1. Washington State University, 2. Cotton Incorporated, 3. USDA-ARS ...
... Lee1, Ping Zheng1, Don Jones2, Richard Percy3, Dorrie Main1 1. Washington State University, 2. Cotton Incorporated, 3. USDA-ARS ...
What is the Human Genome Project?
... cx1remely volatile biotech stocks have grabbed enough attention to finally warrant some level of interest in the Human Genome Project. The Human Genome Project is being primarily funded by the National Institute of Health and the Department of Energy in the United States and the Welleome Trust of th ...
... cx1remely volatile biotech stocks have grabbed enough attention to finally warrant some level of interest in the Human Genome Project. The Human Genome Project is being primarily funded by the National Institute of Health and the Department of Energy in the United States and the Welleome Trust of th ...
ChIP-seq
... •Chromatin state profiling and the ‘histone code’ •Large-scale efforts: ENCODE and the NIH Epigenome Roadmap ...
... •Chromatin state profiling and the ‘histone code’ •Large-scale efforts: ENCODE and the NIH Epigenome Roadmap ...
The Human Genome Project Eric Lander PhD
... Two distinct effects are likely: more sophisticated population studies to find causative genes will be possible availability of the genome sequence will allow the detection of gene expression and proteomic analyses ...
... Two distinct effects are likely: more sophisticated population studies to find causative genes will be possible availability of the genome sequence will allow the detection of gene expression and proteomic analyses ...
Current and Future Projects
... High value, relatively easy to make our own RNA gene set. High value, difficult to expand set to new organisms. (Would need new techniques.) High value, difficult to integrate RNA-seq data into gene set. Moderate value, moderate difficulty to update UCSC genes more often. We have automated about as ...
... High value, relatively easy to make our own RNA gene set. High value, difficult to expand set to new organisms. (Would need new techniques.) High value, difficult to integrate RNA-seq data into gene set. Moderate value, moderate difficulty to update UCSC genes more often. We have automated about as ...
AllScience_is_Comput.. - Buffalo Ontology Site
... (knowledge intensive vs. theory intensive disciplines) increasingly, all these disciplines become like astronomy ...
... (knowledge intensive vs. theory intensive disciplines) increasingly, all these disciplines become like astronomy ...
L04_Public_Resources_Luke_Durban_2015
... variation within and across human populations - ~2M single nucleotide polymorphisms (SNPs) genotyped in ~1000 individuals from 11 populations ...
... variation within and across human populations - ~2M single nucleotide polymorphisms (SNPs) genotyped in ~1000 individuals from 11 populations ...
Origins of Pharmacogenomics
... New technologies that arose from the Human genome Project such as DNA microarrays and lab card or “lab-on-a-chip” devices may eventually make it possible to cheaply and quickly prescreen patients for certain polymorphisms before drug therapy is initiated ...
... New technologies that arose from the Human genome Project such as DNA microarrays and lab card or “lab-on-a-chip” devices may eventually make it possible to cheaply and quickly prescreen patients for certain polymorphisms before drug therapy is initiated ...
DNA switches
... Laboratory-European Bioinformatics Institute, a lead researcher on the project. In one of the Nature papers, researchers link the gene switches to a range of human diseases — multiple sclerosis, lupus, rheumatoid arthritis, Crohn’s disease, celiac disease — and even to traits like height. In large s ...
... Laboratory-European Bioinformatics Institute, a lead researcher on the project. In one of the Nature papers, researchers link the gene switches to a range of human diseases — multiple sclerosis, lupus, rheumatoid arthritis, Crohn’s disease, celiac disease — and even to traits like height. In large s ...
slides - QUBES Hub
... • 20 class meetings of three hours each • 4-5 weeks for background • 5-6 weeks for project • As of fall 2016, 6 sections per quarter ...
... • 20 class meetings of three hours each • 4-5 weeks for background • 5-6 weeks for project • As of fall 2016, 6 sections per quarter ...
Using public resources to understanding associations
... You can download the human genome sequence from here: http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/human/ It looks like this: ...
... You can download the human genome sequence from here: http://www.ncbi.nlm.nih.gov/projects/genome/assembly/grc/human/ It looks like this: ...
Transposable elements I. What is a transposable element?
... 2. a few are beneficial to host: eg. In flies they lengthen chromosome ends without telomeres II. Where are transposons found? A. Found almost everywhere 1. viruses, bacteria, fungi, plants, animals B. major constituents of genome 1. in flies, ~12% of genome 2. in humans, 2 major classes a. LINEs (l ...
... 2. a few are beneficial to host: eg. In flies they lengthen chromosome ends without telomeres II. Where are transposons found? A. Found almost everywhere 1. viruses, bacteria, fungi, plants, animals B. major constituents of genome 1. in flies, ~12% of genome 2. in humans, 2 major classes a. LINEs (l ...
Functional Annotation of Animal Genomes (FAANG)
... • Horse Genome Project (MIT), NHGRI • Chicken Genome Project (Washington University), NHGRI • Although there is no direct involvement with Swine Genome Project, NIH has always been interested in Swine as a model for growth, development, and disease since the pattern of growth and development of pigs ...
... • Horse Genome Project (MIT), NHGRI • Chicken Genome Project (Washington University), NHGRI • Although there is no direct involvement with Swine Genome Project, NIH has always been interested in Swine as a model for growth, development, and disease since the pattern of growth and development of pigs ...
HGP Research
... The long-term goal of the Human Genome Project is to locate the estimated 30,000 or more human genes on all the chromosomes and determine their sequence along each strand of DNA. In June 2000, scientists were able to complete a rough draft of the human genome a year ahead of schedule. Scientists use ...
... The long-term goal of the Human Genome Project is to locate the estimated 30,000 or more human genes on all the chromosomes and determine their sequence along each strand of DNA. In June 2000, scientists were able to complete a rough draft of the human genome a year ahead of schedule. Scientists use ...
Katie-Arabidopsis
... with tiny, white, four-petalled flowers • Six week lifespan • No immediate agricultural importance and is not thought to cure any disease • Prolific seed production and easy cultivation in restricted space • A large number of mutant lines and genomic resources ...
... with tiny, white, four-petalled flowers • Six week lifespan • No immediate agricultural importance and is not thought to cure any disease • Prolific seed production and easy cultivation in restricted space • A large number of mutant lines and genomic resources ...