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Variations
Variations

... (Wikipedia): Functional genomics is a field of molecular biology that attempts to make use of the vast wealth of data produced by genomic projects (such as genome sequencing projects) to describe gene (and protein) functions and interactions. In Ensembl: Regulatory build using ENCODE project informa ...
Whole genome sequencing and assembly of an avian genome, the
Whole genome sequencing and assembly of an avian genome, the

... sequenced fragments and makes use of this information to place the different fragments with respect to each other. This method of genome assembly is known as ‘shotgun’ genome sequencing. In this project we tested the benefits of an alternative method for genome assembly called reduced representation ...
seminar
seminar

... • Commonly multiple mouse alignments can be found for a particular human region, particularly for coding regions. • Net finds best match mouse match for each human region. • Highest scoring chains are used first. • Lower scoring chains fill in gaps within chains inducing a natural hierarchy. ...
The Human Genome Project
The Human Genome Project

... Armed with full genomic information scientists will be able to locate and target the areas of greatest vulnerability in microbes. With full human genomic information they can target and preserve those areas in which mutations make us more susceptible to cancers and neurological disorders. With the i ...
Personal genomics as a major focus of CSAIL research
Personal genomics as a major focus of CSAIL research

... Chromatin state dynamics across nine cell types ...
Institute for Animal Health
Institute for Animal Health

... • Problem: the relationship of RNA abundance to protein abundance is not straight forward – Post-transcriptional regulation • siRNA, miRNA ...
Document
Document

Personal genomics as a major focus of CSAIL research
Personal genomics as a major focus of CSAIL research

MISCELLANEOUS NOTES 1. A Glimpse on Human Genome
MISCELLANEOUS NOTES 1. A Glimpse on Human Genome

... Understanding the genetic bases of heritable diseases also will allow researchers to develop therapeutics at the molecular level, resulting in better treatments with fewer side effects (Jeffords and Daschle 2001). The identification of all human genes, for example, will help improve diagnosis of mos ...
UNIVERSITY COLLEGE LONDON THE UCL CANCER INSTITUTE
UNIVERSITY COLLEGE LONDON THE UCL CANCER INSTITUTE

... Bioinformatician to start immediately. Using experimental and computational approaches, the group has a broad interest in genome organization and its influence on gene regulation. We use molecular methods (Hi-C, 4C-Seq, ChIP and 3D microscopy) and computational analysis to investigate the organisati ...
Keynote for 2008 Genomics Workshop
Keynote for 2008 Genomics Workshop

Proteomics of the chloroplast to chromoplast transition
Proteomics of the chloroplast to chromoplast transition

... determination of their sub-plastidic localisation; creating a data base on chromoplastic proteome; improving genome annotation and include information on post-translational protein modifications and sub-cellular localisation; providing new putative candidate genes involved in the biosynthesis of aro ...
Development of personalized medicine in Japan
Development of personalized medicine in Japan

... Pharmacogenomics7 studies the role of genetics in drug response. Genetic variation of the patients such as SNP8 would respond differently, for example, in drug absorption, distribution, metabolism, and eliminations. Also, the receptor of a drug as a target molecule would be different among patients. ...
IntroToBioinformatics
IntroToBioinformatics

... CSULA and other resources The best way to access articles at Cal State LA is to obtain the exact reference from PubMed. Then search to the CSULA library database for the article: http://www.calstatela.edu/library/mudir1.htm ...
Protocol S1
Protocol S1

... sequencing reads respectively, which were assembled into contigs by utilizing the software package of Phred-Phrap-Consed[3-5],. which resulted in ~12-fold, ~12-fold and nearly 8-fold genome coverage, respectively. PCR amplifications were utilized to close gaps. Genome sequences have been deposited ...
Identifying the genetic and environmental
Identifying the genetic and environmental

Click Here
Click Here

... In February 2009 the Genome Reference Consortium released a new human genome assembly, GRCh37. This new assembly improved the general quality of the whole genome sequence. In addition it also includes alternative assemblies for a number of haplotypic regions. EnsEMBL aims to produce a set of annotat ...
The Human Genome Project
The Human Genome Project

... The Completion of the Human Genome Sequence • June 2000 White House announcement that the majority of the human genome (80%) had been sequenced (working draft). • Working draft made available on the web July 2000 at genome.ucsc.edu. • Publication of 90 percent of the sequence in the February 2001 i ...
Teacher`s Guide - Discovery Education
Teacher`s Guide - Discovery Education

... The primary goal was to locate the estimated 30,000 or more human genes on all the chromosomes and determine their sequence along each strand of DNA. ...
human-genome-project
human-genome-project

Plant Nuclear Genome Size Variation
Plant Nuclear Genome Size Variation

... Euploid variation – polyploidy ~35% of vascular plants are neopolyploids Most are likely paleopolyploids Aneuploid variation – gain or less of one or more chromosomes ...
Prokaryotic genomes
Prokaryotic genomes

... genome from the bacterium Haemophilus influenzae Rd. This approach eliminates the need for initial mapping efforts and is therefore applicable to the vast array of microbial species for which genome maps are unavailable. The H. influenzae Rd genome sequence (Genome Sequence DataBase accession number ...
Human genomes - The University of Auckland
Human genomes - The University of Auckland

... genetic mutations will help us to better understand the disease process and identify new targets for therapeutic intervention. This is ’big data’ research – we typically process 100 billion ‘data points’ for each family, and the data analysis and storage requirements have posed significant challenges ...
postdoc kelp selection GENIALG Roscoff
postdoc kelp selection GENIALG Roscoff

... latissima. The effects of crosses on reproductive success will be investigated by examining the evolution of crossing compatibility with increasing geographic distance. The number of fertilizations and abortion rate will be measured in single-male crosses in laboratory conditions, as estimates of pr ...
The Human Genome Project and Beyond: Canada`s Role
The Human Genome Project and Beyond: Canada`s Role

... screen people for serious diseases, including cancer, as well as to diagnose, treat and perhaps prevent these diseases. Canada was the 7th country to join in the challenge (1992). In all, at least 18 countries participated in the worldwide effort, with significant contributions from the United State ...
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ENCODE

The Encyclopedia of DNA Elements (ENCODE) is a public research project launched by the US National Human Genome Research Institute (NHGRI) in September 2003.Intended as a follow-up to the Human Genome Project (Genomic Research), the ENCODE project aims to identify all functional elements in the human genome.The project involves a worldwide consortium of research groups, and data generated from this project can be accessed through public databases.
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