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AMINO ACID METABOLISM
AMINO ACID METABOLISM

... environment alters the conformation of pepsinogen so that it can cleave itself to yield pepsin. • Pepsin acts as an endopeptidase to cleave dietary proteins with a broad spectrum of specificity, although it prefers to cleave peptide bonds in which the carboxyl group is provided by aromatic or acidic ...
Chapter 5
Chapter 5

... • The coils and folds of secondary structure result from hydrogen bonds between repeating constituents of the polypeptide backbone • Typical secondary structures are a coil called an  helix and a folded structure called a  ...
Request reprint ©
Request reprint ©

... We have established a protocol to study the kinetics of incorporation of 15N into glutamine (Gln), glutamic acid (Glu), alanine (Ala) and proline (Pro) in Aedes aegypti females. Mosquitoes were fed 3% sucrose solutions containing either 80 mM 15NH4Cl or 80 mM glutamine labeled with 15N in either the ...
Characterizing the complexity of enzymes on the basis of their
Characterizing the complexity of enzymes on the basis of their

... active site. Cofactors, both metal ions and small organic molecules, offer an extension of the catalytic power of enzymes. Recently, we have extended the MACiE database to include Metal-MACiE [7,31], in order to fully categorize and annotate the metal ions in MACiE, and their roles and functions. We ...
Organic Compounds - California Science Teacher
Organic Compounds - California Science Teacher

... composed of simpler, smaller molecules called monomers which link together into larger, longer chains called polymers. There are four major classes of biologically important organic compounds. Within a living cell, each of these four major classes has specific important functions. The table on the f ...
Enzymes - Science Prof Online
Enzymes - Science Prof Online

... Image: Enzyme with Cofactor, Wiki. Ribbon-diagram showing carbonic anhydrase II. The grey sphere is the zinc cofactor in the active site. ...
Novel eukaryotic enzymes modifying cell
Novel eukaryotic enzymes modifying cell

Lecture 2 - Washington State University
Lecture 2 - Washington State University

...  Scientists just beginning to understand vast diversity of microbial life  Only ~6,000 of estimated million species of prokaryotes described • 950 genera ...
irm_ch20
irm_ch20

... rich in proline, and proline molecules do not fit well into regular -helices. 20.80 Hemoglobin has four polypeptide chains with each having a heme unit; myoglobin has one polypeptide chain with a heme unit. 20.81 Complete hydrolysis of a peptide under acidic conditions produces free amino acids. Th ...
Protein For Athletes
Protein For Athletes

... maintenance and repair. When those needs are met, excess amino acids are stored as fat, converted to glucose or burned for energy. Does Protein Play a Role in Enhancing Hydration? Sodium is the key element for hydration because sodium increases the physiological desire to drink. Sodium also helps th ...
Chapter 21
Chapter 21

... • Isolated from ground meat, feces, air, fresh water, and other sources, but natural habitat unknown ...
Phenyllactic Acid: A Potential Antimicrobial Compound in Lactic acid
Phenyllactic Acid: A Potential Antimicrobial Compound in Lactic acid

... any suitable ά-keto-acid preferably ά-ketoglutarate in LAB. Hence ά-ketoglutarate is an important that effects the both catabolism of phenylalanine and regulation of PhLA synthesis indirectly [32]. This regulatory effect was observed in L. plantarum resulting in enhanced production of PLA in presenc ...
213lec6
213lec6

THE CITRIC ACID CYCLE
THE CITRIC ACID CYCLE

... s we saw in Chapter 14, some cells obtain energy (ATP) by fermentation, breaking down glucose in the absence of oxygen. For most eukaryotic cells and many bacteria, which live under aerobic conditions and oxidize their organic fuels to carbon dioxide and water, glycolysis is but the first stage in t ...
mic.sgmjournals.org
mic.sgmjournals.org

... (Brega et al., 2004; Martinez & Ljungdahl, 2004). Molecular studies in C. albicans identified Csy1, which senses amino acids in the environment and transduces signals that induce the expression of amino acid permease genes and activate amino acid uptake (Brega et al., 2004). Interestingly, deletion ...
Addition of a photocrosslinking amino acid to the genetic code of
Addition of a photocrosslinking amino acid to the genetic code of

... ll organisms use the same common 20 amino acids as building blocks for the biosynthesis of proteins. The ability to augment the genetically encoded amino acids with unnatural amino acids containing orthogonal chemical handles, photocrosslinking groups, fluorescent probes, redox active groups, or hea ...
Comparison of environmental and isolate Sulfobacillus genomes
Comparison of environmental and isolate Sulfobacillus genomes

... regions were extracted and trimmed with Sickle (available https://github.com/najoshi/sickle), allowing only paired-end reads with length >60 and quality scores >20. For the reference database, 186 sequences were downloaded from the SILVA SSU database representing the 174 sequences of ‘Family XVII In ...
Protein
Protein

... Motor proteins are proteins that turn energy into mechanical work. These proteins are the final step in converting our food into physical work. Specialized motor proteins are also involved in a variety of processes including cell division and muscle contraction. Collagen: The most abundant fibrous p ...
Fig. 1 - Development - The Company of Biologists
Fig. 1 - Development - The Company of Biologists

... metabolic pathways, such as β-oxidation, which is the breakdown of fatty acid molecules into acetyl-CoA. Fatty acids are first activated to acyl-CoA and then through β-oxidation to acetyl-CoA. AcetylCoA generated from either glycolysis or fatty acid β-oxidation is further oxidized in the tricarboxyl ...
0001 fructose intolerance - Western Washington University
0001 fructose intolerance - Western Washington University

... Depletion of tissue ATP occurs through massive degradation to uric acid and impairment of regeneration by oxidative phosphorylation in the mitochondria because of inorganic phosphate depletion. ...
Outcomes and evidence requirements
Outcomes and evidence requirements

... Providers must be granted consent to assess against standards (accredited) by NZQA, before they can report credits from assessment against unit standards or deliver courses of study leading to that assessment. Industry Training Organisations must be granted consent to assess against standards by NZQ ...
Oxidation – Reduction Reactions
Oxidation – Reduction Reactions

... Lead storage battery: lead serves as the anode and lead coated with lead dioxide serves as the cathode Dry cell battery: in its acid version, the zinc inner case acts as the anode, while a carbon rod in contact with a moist paste of solid MnO2, solid NH4Cl, and a carbon rod act as the cathode Fuel c ...
Separation of Racemic Mixtures of Amino Acids Using Chiral Eluents
Separation of Racemic Mixtures of Amino Acids Using Chiral Eluents

... Usually, increasing the concentration of organic modifier in the eluent in the reversed phase chromatography leads to reduction of the retention times of the solutes because of an increasing solvent strength. The influence of methanol as modifier was investigated with the aliphatic amino acids Val, ...
Alkaptonuria and Aspergillus nidulans
Alkaptonuria and Aspergillus nidulans

... particularly nose bleeds. Jaundice may or may not be prominent. Despite vigorous therapy, death from hepatic failure frequently occurs between three and nine months of age unless a liver transplantation is performed. ...
9 biological oxidation, electron transfer chain and oxidative
9 biological oxidation, electron transfer chain and oxidative

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Metabolism



Metabolism (from Greek: μεταβολή metabolē, ""change"") is the set of life-sustaining chemical transformations within the cells of living organisms. These enzyme-catalyzed reactions allow organisms to grow and reproduce, maintain their structures, and respond to their environments. The word metabolism can also refer to all chemical reactions that occur in living organisms, including digestion and the transport of substances into and between different cells, in which case the set of reactions within the cells is called intermediary metabolism or intermediate metabolism.Metabolism is usually divided into two categories: catabolism, the breaking down of organic matter by way of cellular respiration, and anabolism, the building up of components of cells such as proteins and nucleic acids. Usually, breaking down releases energy and building up consumes energy.The chemical reactions of metabolism are organized into metabolic pathways, in which one chemical is transformed through a series of steps into another chemical, by a sequence of enzymes. Enzymes are crucial to metabolism because they allow organisms to drive desirable reactions that require energy that will not occur by themselves, by coupling them to spontaneous reactions that release energy. Enzymes act as catalysts that allow the reactions to proceed more rapidly. Enzymes also allow the regulation of metabolic pathways in response to changes in the cell's environment or to signals from other cells.The metabolic system of a particular organism determines which substances it will find nutritious and which poisonous. For example, some prokaryotes use hydrogen sulfide as a nutrient, yet this gas is poisonous to animals. The speed of metabolism, the metabolic rate, influences how much food an organism will require, and also affects how it is able to obtain that food.A striking feature of metabolism is the similarity of the basic metabolic pathways and components between even vastly different species. For example, the set of carboxylic acids that are best known as the intermediates in the citric acid cycle are present in all known organisms, being found in species as diverse as the unicellular bacterium Escherichia coli and huge multicellular organisms like elephants. These striking similarities in metabolic pathways are likely due to their early appearance in evolutionary history, and their retention because of their efficacy.
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