single page dosing summary
... Prior to using a nasal medication, inspect the nostril for significant amounts of blood or mucous discharge. Presence of these will limit medication absorption. Suctioning the nasal passage prior to delivery and/or alternated delivery options should be considered. ...
... Prior to using a nasal medication, inspect the nostril for significant amounts of blood or mucous discharge. Presence of these will limit medication absorption. Suctioning the nasal passage prior to delivery and/or alternated delivery options should be considered. ...
Deer Sedation
... mild effect; may be suitable for mothering, transport, Tb-testing up to 0.25-0.3 mg/kg i/m or i/v ...
... mild effect; may be suitable for mothering, transport, Tb-testing up to 0.25-0.3 mg/kg i/m or i/v ...
Guidelines for Opioids EN
... Subcutaneous dose is usually ½ p.o. dose. When converting from one opioid to another, it is often possible to reduce the calculated equivalent dose by 33%. This is because of incomplete cross-tolerance. When opioids are changed due to toxicity (‘opioid rotation”), the calculated equivalent dose may ...
... Subcutaneous dose is usually ½ p.o. dose. When converting from one opioid to another, it is often possible to reduce the calculated equivalent dose by 33%. This is because of incomplete cross-tolerance. When opioids are changed due to toxicity (‘opioid rotation”), the calculated equivalent dose may ...
Nasal Drug Delivery in EMS
... µ/kg/hr infusion IV. Effective intranasal fentanyl post-op pain dose: 1.5 µg/kg Opiate dependent patients - may need even higher doses than post-operative patients. No titration- Due to rapid onset of action intranasal pain meds can be titrated to effect. The single dose given in this study is i ...
... µ/kg/hr infusion IV. Effective intranasal fentanyl post-op pain dose: 1.5 µg/kg Opiate dependent patients - may need even higher doses than post-operative patients. No titration- Due to rapid onset of action intranasal pain meds can be titrated to effect. The single dose given in this study is i ...
Fentanyl Buccal Lozenges (Actiq®)
... medication may be utilized as directed by the patient’s healthcare provider. When an adequate fentanyl buccal film dose has been determined, the patient should receive a prescription for the effective dosage strength and use or dispose of the remaining unused 200 mcg films. Fentanyl buccal films sho ...
... medication may be utilized as directed by the patient’s healthcare provider. When an adequate fentanyl buccal film dose has been determined, the patient should receive a prescription for the effective dosage strength and use or dispose of the remaining unused 200 mcg films. Fentanyl buccal films sho ...
pain management guidelines - About PRC
... 2. Base administration schedule on the analgesic's duration of effect. Best to use sustained release opioids for scheduled dosing and always use immediate release opioids for rescue or breakthrough dosing. Do not crush or chew extended-release preparations. 3. In opioid naïve patients start with low ...
... 2. Base administration schedule on the analgesic's duration of effect. Best to use sustained release opioids for scheduled dosing and always use immediate release opioids for rescue or breakthrough dosing. Do not crush or chew extended-release preparations. 3. In opioid naïve patients start with low ...
Developing an Effective Oral Analgesic Regimen
... Peak analgesic effect occurs in 60-90 minutes Expected total duration of analgesia of 2-4 hours. Standard reference sources generally cite q 4 hour dosing interval for the singleagent opioids ...
... Peak analgesic effect occurs in 60-90 minutes Expected total duration of analgesia of 2-4 hours. Standard reference sources generally cite q 4 hour dosing interval for the singleagent opioids ...
Kitsap County Commission on Children and Youth agenda packet
... There is currently a lack of safe, convenient and legal disposal options for unused medications in Kitsap County. Unused, unwanted and expired medicines in your home pose a risk to you, your family, our community, and the environment. Medicine take-back programs provide a secure and environmentally- ...
... There is currently a lack of safe, convenient and legal disposal options for unused medications in Kitsap County. Unused, unwanted and expired medicines in your home pose a risk to you, your family, our community, and the environment. Medicine take-back programs provide a secure and environmentally- ...
Pain Management in Palliative Care
... Useful in patients with renal failure as tends to accumulate less ...
... Useful in patients with renal failure as tends to accumulate less ...
Nasal Drug Delivery in EMS
... Short acting – no long side effects from drug No special training is required to deliver the medication No shots are needed – Totally Painless No needle stick risk, no infection risk Patients (and family) really like this approach Works even if patient cannot swallow or has N/V Socially acceptable ( ...
... Short acting – no long side effects from drug No special training is required to deliver the medication No shots are needed – Totally Painless No needle stick risk, no infection risk Patients (and family) really like this approach Works even if patient cannot swallow or has N/V Socially acceptable ( ...
Fentanyl Buccal Lozenges (Actiq®)
... managed with this dose of fentanyl sublingual spray, a patient may use a second dose as directed by their health care provider, with no more than two doses being used to treat any breakthrough pain episode. Again, patients must wait at least four hours before treating subsequent breakthrough pain e ...
... managed with this dose of fentanyl sublingual spray, a patient may use a second dose as directed by their health care provider, with no more than two doses being used to treat any breakthrough pain episode. Again, patients must wait at least four hours before treating subsequent breakthrough pain e ...
Dose titration protocol for Intranasal fentanyl
... Dose titration phase for intranasal opiates in hospice patients. Goal – Find the appropriate, safe dose of medication that satisfactorily controls the patients pain, yet dose not over sedate them or lead to respiratory compromise. Once the appropriate dose is found – this should be used for all futu ...
... Dose titration phase for intranasal opiates in hospice patients. Goal – Find the appropriate, safe dose of medication that satisfactorily controls the patients pain, yet dose not over sedate them or lead to respiratory compromise. Once the appropriate dose is found – this should be used for all futu ...
DUROGESIC Transdermal System
... less than 8 breaths/minute or a pCO2 greater than 55 mm Hg. Episodes of slow respiration may occur at any time during therapy despite most patients developing tolerance to fentanylinduced hypoventilation with long-term use. Hypoventilation can occur throughout the therapeutic range of fentanyl serum ...
... less than 8 breaths/minute or a pCO2 greater than 55 mm Hg. Episodes of slow respiration may occur at any time during therapy despite most patients developing tolerance to fentanylinduced hypoventilation with long-term use. Hypoventilation can occur throughout the therapeutic range of fentanyl serum ...
Morphine vs Hydromorphone vs Oxycodone vs the Patch
... Fentanyl: Transdermal (Duragesic) and parenteral formulations are available. · high lipid solubility · 50100 time more potent than morphine · Transdermal patch convenient in patients with stable pain control. Caution advised in uncontrolled pain syndromes (not suitable for rapid titration) · Possi ...
... Fentanyl: Transdermal (Duragesic) and parenteral formulations are available. · high lipid solubility · 50100 time more potent than morphine · Transdermal patch convenient in patients with stable pain control. Caution advised in uncontrolled pain syndromes (not suitable for rapid titration) · Possi ...
Rita Mannarino - Opioids for the Non
... * Pete is an ex-smoker, having quit about 12 years ago just prior to the birth of his first grandchild and after he started having issues with dyspnea for which he required the use of puffers ...
... * Pete is an ex-smoker, having quit about 12 years ago just prior to the birth of his first grandchild and after he started having issues with dyspnea for which he required the use of puffers ...
The Difficult to Sedate ICU Patient
... or hypnosis • Lots of side effects (itching, nausea, constipation, urine retention, myoclonus, respiratory depression) • Very little direct organ toxicity ...
... or hypnosis • Lots of side effects (itching, nausea, constipation, urine retention, myoclonus, respiratory depression) • Very little direct organ toxicity ...
Abstral - AZBlue
... older who are already receiving and who are tolerant to around-the-clock opioid therapy for their underlying persistent cancer pain. Patients considered opioid tolerant are those who are taking, for one week or longer, around-the-clock medicine consisting of at least 60 mg of oral morphine per day, ...
... older who are already receiving and who are tolerant to around-the-clock opioid therapy for their underlying persistent cancer pain. Patients considered opioid tolerant are those who are taking, for one week or longer, around-the-clock medicine consisting of at least 60 mg of oral morphine per day, ...
Opioid Pharmacology: How to choose and how to use
... • Widely available in multiple forms: oral pill and liquid, pills, parenteral • More rapid onset and shorter half life • ?less histamine release than morphine ...
... • Widely available in multiple forms: oral pill and liquid, pills, parenteral • More rapid onset and shorter half life • ?less histamine release than morphine ...
Sublimaze® CII (fentanyl citrate injection) - Akorn
... SUBLIMAZE plasma protein binding capacity decreases with increasing ionization of the drug. Alterations in pH may affect its distribution between plasma and the central nervous system. It accumulates in skeletal muscle and fat, and is released slowly into the blood. SUBLIMAZE, which is primarily tra ...
... SUBLIMAZE plasma protein binding capacity decreases with increasing ionization of the drug. Alterations in pH may affect its distribution between plasma and the central nervous system. It accumulates in skeletal muscle and fat, and is released slowly into the blood. SUBLIMAZE, which is primarily tra ...
Fentanyl - Spirit of Healing: Alberta First Nations Conquering
... When tested with mice, Naloxone successfully reversed the analgesic (painkilling) effects of W-3. Reversal of respiratory depression, the means by which opioid overdose causes death, was not assessed. While reversal has never been tested in humans, naloxone should ...
... When tested with mice, Naloxone successfully reversed the analgesic (painkilling) effects of W-3. Reversal of respiratory depression, the means by which opioid overdose causes death, was not assessed. While reversal has never been tested in humans, naloxone should ...
Pain Management - Stueck Pharmacy Ltd.
... ◦ Duration of pain relief: initially 4-8 hrs, increases to 24-48 hrs with repeated doses ◦ Takes 3-5 days to reach plasma steady state ...
... ◦ Duration of pain relief: initially 4-8 hrs, increases to 24-48 hrs with repeated doses ◦ Takes 3-5 days to reach plasma steady state ...
Counterfeit Prescription Pills Containing Fentanyls: A
... to reduce the amount of opioid pills available on the market for abuse include DEA’s National Take-Back Initiative, and education for doctors on the dangers of opioid medications. The arrival of large amounts of counterfeit prescription drugs containing fentanyls on the market threatens to devalue s ...
... to reduce the amount of opioid pills available on the market for abuse include DEA’s National Take-Back Initiative, and education for doctors on the dangers of opioid medications. The arrival of large amounts of counterfeit prescription drugs containing fentanyls on the market threatens to devalue s ...
Injecting Fentanyl - Minimising the Risks
... Fentanyl is a very powerful synthetic opioid that is used in medicine to treat chronic pain or as an anaesthetic during surgery. It will often be prescribed when other strong pain killers (such as morphine or oxycodone) are unsuitable or ineffective. Fentanyl is being used by injecting drug users in ...
... Fentanyl is a very powerful synthetic opioid that is used in medicine to treat chronic pain or as an anaesthetic during surgery. It will often be prescribed when other strong pain killers (such as morphine or oxycodone) are unsuitable or ineffective. Fentanyl is being used by injecting drug users in ...
Fentanyl
Fentanyl (also known as fentanil, brand names Sublimaze, Actiq, Durogesic, Duragesic, Fentora, Matrifen, Haldid, Onsolis, Instanyl, Abstral, Lazanda and others) is a potent, synthetic opioid analgesic with a rapid onset and short duration of action. It is a strong agonist at the μ-opioid receptors. Historically, it has been used to treat breakthrough pain and is commonly used in pre-procedures as a pain reliever as well as an anesthetic in combination with a benzodiazepine.Fentanyl is approximately 80 to 100 times more potent than morphine and roughly 40 to 50 times more potent than pharmaceutical grade (100% pure) heroin.Fentanyl was first synthesized by Paul Janssen in 1960 following the medical inception of pethidine several years earlier. Janssen developed fentanyl by assaying analogues of the structurally related drug pethidine for opioid activity. The widespread use of fentanyl triggered the production of fentanyl citrate (the salt formed by combining fentanyl and citric acid in a 1:1 stoichiometry), which entered the clinical practice as a general anaesthetic under the trade name Sublimaze in the 1960s. Following this, many other fentanyl analogues were developed and introduced into medical practice, including sufentanil, alfentanil, remifentanil, and lofentanil.In the mid-1990s, fentanyl was first introduced for widespread palliative use with the clinical introduction of the Duragesic patch, followed in the next decade by the introduction of the first quick-acting prescription formulations of fentanyl for personal use, the Actiq lollipop and Fentora buccal through the delivery method of EstradiolMylan transdermal patches, as of 2012 fentanyl was the most widely used synthetic opioid in clinical practice, with several new delivery methods now available, including a sublingual spray for cancer patients. In 2013 1700 kilograms were used globally.Fentanyl and other opioids are used recreationally. Deaths have resulted from both recreational and improper medical use.