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Dissecting Gene Expression Changes Accompanying a Ploidy
Dissecting Gene Expression Changes Accompanying a Ploidy

... on chromosome 21 has been shown to be increased (MAO et al. 2003), mirroring the increased copy number of those genes. This increase in gene expression can produce phenotypic effects in several ways. One mechanism is via direct downstream effects of the overexpressed genes. For example, individuals ...
Topic 8 - OoCities
Topic 8 - OoCities

... The chromosomes are visible here and each chromosome is composed of two sister chromatids attached at the centromere. Each two chromosomes of a pair come close together and are crossed at areas called chiasmata. The process of crossing over occurs between the chromatids of the two homologous chromos ...
Part 2 - Laboratory of Aquaculture & Artemia Reference Center
Part 2 - Laboratory of Aquaculture & Artemia Reference Center

... This review claims attention of genomic researchers about a tiny crustacean Artemia. Apart from serving as livefeed in aquaulture industries, Artemia seems to be the ultimate model for several genomic puzzles. Genomic research on Artemia at the molecular level is still in its infancy and a complete ...
De novo Structure Variations of the Y Chromosome in a 47,XXY
De novo Structure Variations of the Y Chromosome in a 47,XXY

... and that the XXY abnormality was caused by non-disjunction of the maternal X chromosomes during meiosis II. The Affymetrix Genome-Wide Human SNP Array 6.0 was then used to detect the CNVs in the genome of the patient. Two large deletions were identified on the short arm of the Y chromosome (fig. 1c) ...
Pseudogene function: regulation of gene expression
Pseudogene function: regulation of gene expression

... Let us evaluate the above-discussed evolutionary scenario (Figure 2) for the origin of these functional pseudogenes. To begin with, the relatively low degree of sequence similarity between the paralogous gene and pseudogenes weakens the argument that they necessarily arose from a common ancestral ge ...
The silence of genes
The silence of genes

... encountered the phenomenon three millennia ago, when they observed that a female horse crossed with a male donkey yielded a mule, whereas a male horse crossed with a female donkey gave a ‘hinny’. The mule has longer ears, whereas the hinny has stronger legs and a thicker mane. The differences betwee ...
Proposal 3: Polygene
Proposal 3: Polygene

... About 400-500 BC1 seeds will be planted, and the resulting plants individually selected for the desirable characteristics mentioned above. Their seeds will have resulted from random, natural pollination in the field as the plants grew. We will harvest and pool the seeds of all the selected plants. T ...
Systems-wide Chicken DNA Microarrays, Gene Expression Profiling
Systems-wide Chicken DNA Microarrays, Gene Expression Profiling

Phenotypic comparison between maternal and
Phenotypic comparison between maternal and

... andf or repression of kni and neighbouring gap genes, such as Kr and giant (Petschek et al. 1987), which affects the development of the sixth through seventh abdominal segment (see legend of Table L). The differences between the phenotype of kni and ...
Practice test answers
Practice test answers

... 9. Each gene occupies a specific place on a chromosome. This is referred to as the genes a. genetic map c. linkage b. locus d. neighborhood. ANSWER: B 10. When genes are located on the same chromosome and when they tend to be inherited together they are considered ___________. a. a couple c. indepen ...
Document
Document

... the membrane and allow lactose to diffuse into the cell. ...
Chapter 11 Regulation of Gene Expression
Chapter 11 Regulation of Gene Expression

... such as those in this chapter, DNA is almost never entirely separated from chromatin proteins during interphase, and histones remain associated with the DNA at many positions along the molecule even during transcription. The rate of transcription is therefore also controlled by the accessibility of ...
genetics, 021816 - Biology East Los Angeles College
genetics, 021816 - Biology East Los Angeles College

... contains the processing areas for verbal and mathematical abilities. Left-handed—the right hemisphere often contains the areas for verbal and math abilities. Einstein’s brain, from the medical journal, The Lancet ...
Chromosome Variations
Chromosome Variations

... • Some duplications are “dispersed”, found in very different locations from each other. • Other duplications are “tandem”, found next to each other. • Tandem duplications play a major role in evolution, because it is easy to generate extra copies of the duplicated genes through the process of unequa ...
Complementation
Complementation

... Cavefish natural history -The Mexican cave fish lives in a series of unconnected caves. -Fish found in the caves have been blind for millennia. -Cavefish can still interbreed with surface fish! Are mutations in the same gene or different genes responsible for blindness in separated cavefish? ...
No disease
No disease

Antibiotic Resistance and Genetically Engineered Plants
Antibiotic Resistance and Genetically Engineered Plants

... The process of inserting a gene of interest into a plant is crude, haphazard, and random. Scientists cannot easily determine where a gene will land, or even if a gene has been successfully incorporated into a plant cell. There are two common methods of gene insertion. The first involves a “gene gun ...
Clustering approaches for temporal microarray gene expression data
Clustering approaches for temporal microarray gene expression data

... different controlling genes (example, does gene 1 express or suppress gene 2?). Third, it allows scientists to study disease progression (such as cancer) over time and in greater depth. Fourth, time-series microarrays enable novel methods of drug discovery by allowing for the observation of genetic ...
Lesson Overview - Enfield High School
Lesson Overview - Enfield High School

Molecular characterization of the uncultivatable hemotropic
Molecular characterization of the uncultivatable hemotropic

... Mycoplasma haemofelis is a pathogenic feline hemoplasma. Despite its importance, little is known about its metabolic pathways or mechanism of pathogenicity due to it being uncultivatable. The recently sequenced M. haemofelis str. Langford 1 genome was analysed and compared to those of other availabl ...
Chapt 16: Other RNA Processing 16.1 Ribosomal RNA Processing
Chapt 16: Other RNA Processing 16.1 Ribosomal RNA Processing

... • Fission yeast Schizosaccharomyces pombe has active transcription of reverse strand at outermost regions of centromere – Rare forward transcripts can base-pair with reverse transcript to trigger RNAi – Recruits histone methyltransferase, methylates Lys-9 of H3 – This recruits Swi6, causing heteroch ...
The constitution and the control of the ovarian
The constitution and the control of the ovarian

... arrested at the diplotene stage. One main factor involved in ultimate stage of ovarian follicle formation is FIGLA, a germ cell-specific bHLH transcription factor (Fig. 1). Female mice lacking Figla are sterile due to the absence of follicles and oocytes (Soyal et al., 2000). The defect appears afte ...
A minimal gene set for cellular life derived by comparison of
A minimal gene set for cellular life derived by comparison of

Deletions of ultraconserved elements have no obvious phenotype
Deletions of ultraconserved elements have no obvious phenotype

... for identifying functionally important genomic sequences [1,2]. Ultraconserved elements have been defined as a group of extremely conserved sequences that show 100% identity over 200 bp or greater between the human, mouse, and rat genomes [3]. This category of extreme evolutionary sequence conservati ...
Expression profiling reveals off
Expression profiling reveals off

... On the basis of published reports that gene silencing was abolished by single nucleotide changes in the siRNA sequence2,6, we would not have predicted that this limited degree of sequence similarity would be sufficient for transcript silencing. However, to test this possibility, we systematically su ...
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Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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