TOPIC 16: REGULATION OF GENE EXPRESSION
... (a) Enhancers or distal control elements- located large distances from the protein coding portions of the gene (100 to 1,000 bp away) (b) Proximal control elements- located near the promoter (c) Promoter- begins with a TATA box; site of binding of RNA polymerase (d) Transcription factors- DNA bindin ...
... (a) Enhancers or distal control elements- located large distances from the protein coding portions of the gene (100 to 1,000 bp away) (b) Proximal control elements- located near the promoter (c) Promoter- begins with a TATA box; site of binding of RNA polymerase (d) Transcription factors- DNA bindin ...
Presentation - PHI-base
... Forward and Reverse Genetics Pathogen transformation involving protoplast or Agrobacterium mediated Gene disruption, replacement or silencing Purification of secreted proteins Map based cloning ...
... Forward and Reverse Genetics Pathogen transformation involving protoplast or Agrobacterium mediated Gene disruption, replacement or silencing Purification of secreted proteins Map based cloning ...
Evolutionary genomics
... formation, or the addition of prosthetic groups, carbohydrates or lipids. - reversible modifications include such things as phosporylation, acetylation, or methylation. - the net outcome is that the same gene can produce many different protein products. - this fact will greatly complicate the study ...
... formation, or the addition of prosthetic groups, carbohydrates or lipids. - reversible modifications include such things as phosporylation, acetylation, or methylation. - the net outcome is that the same gene can produce many different protein products. - this fact will greatly complicate the study ...
encode 2012
... • The vast majority (80.4%) of the human genome participates in at least one biochemical RNA- and/or chromatin-associated event in at least one cell type. • Primate-specific elements as well as elements without detectable mammalian constraint show, in aggregate, evidence of negative selection; thus ...
... • The vast majority (80.4%) of the human genome participates in at least one biochemical RNA- and/or chromatin-associated event in at least one cell type. • Primate-specific elements as well as elements without detectable mammalian constraint show, in aggregate, evidence of negative selection; thus ...
Evolution of eukaryote genomes
... •Introns are more prevalent and longer in the large eukaryotic genome. Intergenic regions are also longer in the larger eukaryotic genomes. •The number of distinct protein domain encoded by genes does not vary much between genome sizes. Predicted number of proteins domains encoded by A. thaliana, D ...
... •Introns are more prevalent and longer in the large eukaryotic genome. Intergenic regions are also longer in the larger eukaryotic genomes. •The number of distinct protein domain encoded by genes does not vary much between genome sizes. Predicted number of proteins domains encoded by A. thaliana, D ...
Nature v. Nurture
... Twenty-two of these pairs, called autosomes, look the same in both males and females. The 23rd pair, the sex chromosomes, differ between males and females. Females have two copies of the X chromosome, while males have one X and one Y chromosome. ...
... Twenty-two of these pairs, called autosomes, look the same in both males and females. The 23rd pair, the sex chromosomes, differ between males and females. Females have two copies of the X chromosome, while males have one X and one Y chromosome. ...
Document
... to the hypothesis that their adaptation to different aphid species is an ongoing process. ...
... to the hypothesis that their adaptation to different aphid species is an ongoing process. ...
Homeobox Genes U6[1].
... such as Drosophila • Homologous genes are evolutionarily derived from the same ancestral gene and have similar DNA sequences • Hox genes in mice 1. Follow the colinearity rule (are expressed in the same sequence as in simpler animals) 2. Have a key role in establishing anteroposterior axis and contr ...
... such as Drosophila • Homologous genes are evolutionarily derived from the same ancestral gene and have similar DNA sequences • Hox genes in mice 1. Follow the colinearity rule (are expressed in the same sequence as in simpler animals) 2. Have a key role in establishing anteroposterior axis and contr ...
Document
... produce 4 haploid. • This gives you many different combinations of genes to be passed on. It’s all chance on the ones you get. ...
... produce 4 haploid. • This gives you many different combinations of genes to be passed on. It’s all chance on the ones you get. ...
Sample questions - I Exam
... In humans, the ability to taste the chemical phenylthiocarbamide (PTC) is attributed to the dominant allele of a gene, denoted T, located on chromosome 7. The recessive allele of this gene is designated t. Individuals with the genotypes T/T and T/t are tasters of PTC, and those with the genotype t/t ...
... In humans, the ability to taste the chemical phenylthiocarbamide (PTC) is attributed to the dominant allele of a gene, denoted T, located on chromosome 7. The recessive allele of this gene is designated t. Individuals with the genotypes T/T and T/t are tasters of PTC, and those with the genotype t/t ...
Chapter 15 Chromosomal Basis of Heredity
... 5. Explain how crossing over can unlink genes. 6. Explain how Sturtevant created linkage maps. 7. Define a map unit. 8. Explain why Mendel did not find linkage between seed color and flower color, despite the fact that these genes are on the same chromosome. 9. Explain how genetic maps are construct ...
... 5. Explain how crossing over can unlink genes. 6. Explain how Sturtevant created linkage maps. 7. Define a map unit. 8. Explain why Mendel did not find linkage between seed color and flower color, despite the fact that these genes are on the same chromosome. 9. Explain how genetic maps are construct ...
Genetics - I Heart Science
... chromosomes in the cell nuclei of an organism or species. By studying karyotypes, you can determine what traits are inherited. ...
... chromosomes in the cell nuclei of an organism or species. By studying karyotypes, you can determine what traits are inherited. ...
Dihybrid crosses and gene linkage
... A new shuffling of the alleles has created a new combination which does not match either of the parents’ genotypes The term recombinant is used to describe both the new chromosome and the resulting organism. Recombinants form through the process of crossing over ...
... A new shuffling of the alleles has created a new combination which does not match either of the parents’ genotypes The term recombinant is used to describe both the new chromosome and the resulting organism. Recombinants form through the process of crossing over ...
Human Heredity
... The female is a sex linked carrier for “red glowing nose”…but her phenotype is black nose….and she is ...
... The female is a sex linked carrier for “red glowing nose”…but her phenotype is black nose….and she is ...
Sex Chromosomes and Male Functions
... obvious: genes with male germline function would be enriched in autosomes after sufficient evolutionary time. This prediction is well corroborated by Drosophila expression analysis using DNA microarray technology26,28 and for many individual genes.17,25-28 Male germline genes also show a strong pref ...
... obvious: genes with male germline function would be enriched in autosomes after sufficient evolutionary time. This prediction is well corroborated by Drosophila expression analysis using DNA microarray technology26,28 and for many individual genes.17,25-28 Male germline genes also show a strong pref ...
Classification (Supervised Clustering)
... Reducing the Number of Genes 1.With n samples, use the n-k most significantly differentially expressing genes. 2. Cluster the genes and take the most significantly differentially expressing gene in each cluster. 3. Add variables to your discrimination function stepwise. 4. PAM - shrink the group ce ...
... Reducing the Number of Genes 1.With n samples, use the n-k most significantly differentially expressing genes. 2. Cluster the genes and take the most significantly differentially expressing gene in each cluster. 3. Add variables to your discrimination function stepwise. 4. PAM - shrink the group ce ...
PDF
... Hox gene family are turned on and off in zebrafish fins and mouse limbs. Two Hox gene clusters, HoxA and HoxD, are known to function in patterning the developing vertebrate limb. In land animals, but not in fish, HoxD has what is known as a ‘‘bimodal expression pattern,’’ meaning that one subset of ...
... Hox gene family are turned on and off in zebrafish fins and mouse limbs. Two Hox gene clusters, HoxA and HoxD, are known to function in patterning the developing vertebrate limb. In land animals, but not in fish, HoxD has what is known as a ‘‘bimodal expression pattern,’’ meaning that one subset of ...
Pisum Genetics Volume 25 1993 Research Reports 1 Genes a and
... segregation data 258 A D : 93 A d : 103 a (repulsion) became 258 A D : 93 A d : 93 a D : 10 a d; and 215 A D : 125 A d : 101 a (repulsion) became 215 A D : 125 A d: 101 a D : 0 a d! In the latter case the entire class a was less than A d. This procedure introduces artifactual information not resulti ...
... segregation data 258 A D : 93 A d : 103 a (repulsion) became 258 A D : 93 A d : 93 a D : 10 a d; and 215 A D : 125 A d : 101 a (repulsion) became 215 A D : 125 A d: 101 a D : 0 a d! In the latter case the entire class a was less than A d. This procedure introduces artifactual information not resulti ...