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genome - Microme
genome - Microme

... Functional annotation  Public tools : BLAST (searches in specialized databases and Uniprot), InterproScan (domains and functional sites), COGnitor (COG protein ...
Clinical Next Generation Sequencing (From Bench to Clinitions)
Clinical Next Generation Sequencing (From Bench to Clinitions)

... of interest (custom content), targets within genes, or mitochondrial DNA. ...
Recombination Frequency - Westford Academy Ap Bio
Recombination Frequency - Westford Academy Ap Bio

... • In rabbits, black (B) is dominant to brown (b), while full color (F) is dominant to chinchilla (f). The genes controlling these traits are linked. • The following cross was made: rabbits heterozygous for both traits that express black, full color, (BbFf) with rabbits that are brown, chinchilla (bb ...
Functional second genes generated by retrotransposition of the X
Functional second genes generated by retrotransposition of the X

... RP genes and have localized them to autosomes. Because these genes have no introns in their coding regions, they were most likely produced by retrotransposition of the original X-linked genes during evolution. Although each mammalian RP is typically encoded by a single gene, this functional gene als ...
TASSEL
TASSEL

... Stretches of DNA that are closely linked to the genes that underlie the trait. QTLs can be molecularly identified (for example, with PCR or AFLP) to help map regions of the genome. This can be an early step in identifying and sequencing these genes. Their phenotypes typically vary along a continuous ...
PDF
PDF

... Availability: SCPD can be accessed from the URL http://cgsigma.cshl.org/jian. The database is continually updated. Contact: [email protected] or [email protected] Introduction The complete genomic sequence of the yeast Saccharomyces cerevisiae reveals >6000 open reading frames (ORFs). About 3000 have been ...
The worm in us – Caenorhabditis elegans as a model of
The worm in us – Caenorhabditis elegans as a model of

Multiple Alleles, Polygenic and Sex
Multiple Alleles, Polygenic and Sex

... Genes located on the X or Y chromosomes Most sex-linked genes are found on the X chromosome - The human Y chromosome is much smaller and appears to contain only few genes. - Father determines the sex of the offspring - The chance is always 50-50 for either sex - A recessive gene has no matching gene ...
Hypergeometric Tests for Gene Lists
Hypergeometric Tests for Gene Lists

... • Use the method of your choice. • We will use a t-test for differential expression between two groups. ttests = rowttests(nsFiltered, "mol.biol") ttestCutoff = 0.05 smPV = ttests$p.value < ttestCutoff ...
Designer Babies & the government
Designer Babies & the government

... • In the future we may be able to "cure" genetic diseases in embryos by replacing faulty sections of DNA with healthy DNA. • This is called germ line therapy and is carried out on an egg, sperm or a tiny fertilized embryo. • Such therapy has successfully been done on animal embryos, • but at present ...
Document
Document

... traits are transferred from one generation to the next. ...
Identification of reproductive genes by gene targeting strategies
Identification of reproductive genes by gene targeting strategies

... barriers, the major contributor of speciation. Taking both ends into consideration will surely help us to elucidate the underlying mechanisms of reproduction. Known genes involved in reproduction can be readily used to create knockout mice for loss-of-function studies. However, at this moment, many ...
Linking gene expression mentions to anatomical
Linking gene expression mentions to anatomical

... 2. If there is only one gene and one cell type, associate them with the trigger 3. If the genes, cell types and trigger conform to certain patterns, associate them with the trigger 4. Associate trigger to the gene and cell type mentions with shortest tree distance to the trigger ...
Chapter 15~ The Chromosomal Basis of Inheritance
Chapter 15~ The Chromosomal Basis of Inheritance

... Pleiotrophy ...
Exercise
Exercise

... What other genes have a similar expression profile to mat1a in experiment E-GEOD-4262? To answer this question, go to the experiment page and run a similarity search. The similarity search returned Pah, Cyp4a10, Fgb and Ugt2b1 ...
HbVar_PhenCode - Center for Comparative Genomics and
HbVar_PhenCode - Center for Comparative Genomics and

... locus specific data • MANY more people go to genome browsers than to locus specific databases • Data on variants and mutations can be easily displayed as a track on the browser • Information from other resources can be readily be integrated with variation information – E.g. ENCODE data on transcript ...
Patterns of inheritance
Patterns of inheritance

... Recessive traits and alleles - the offspring will only get the trait if both parents contribute the trait. These traits can be carried in the persons genes, without appearing in the person. They are represented by a lower case letter (a, for example) – Eg, a dark-haired person may have one gene for ...
MEIOSIS LAB Name: AP BIOLOGY Period: Crossing Over during
MEIOSIS LAB Name: AP BIOLOGY Period: Crossing Over during

... (either tan or wild-type). Therefore, segregation of these genes has occurred at the first meiotic division (MI). The second meiotic division (MII) results in four cells, each with the haploid number of chromosomes (1N). A mitotic division simply duplicates these cells, resulting in 8 spores. They a ...
Lecture 12
Lecture 12

... caused by various phenomena, including gene silencing, is frequently observed. Here, we show that stable, high-level transgene expression is obtained using Arabidopsis thaliana posttranscriptional gene silencing (PTGS) sgs2 and sgs3 mutants. In populations of first generation (T1) plants transformed ...
Chromosomal Basis of Inheritance
Chromosomal Basis of Inheritance

... specific chromosome came from Thomas Hunt Morgan  Morgan’s experiments with fruit flies provided convincing evidence that chromosomes are the location of Mendel’s heritable factors  Several characteristics make fruit flies a convenient ...
ClusteringLab_2012_ANSWERS
ClusteringLab_2012_ANSWERS

... Open the file in Cluster, select genes that are affected >2X (1 in log2 space) in at least 4 experiments, and cluster the data using Pearson correlation (uncentered) and centroid linkage. View the data in a New Window of Treeview (in your existing browser, go to “Window” and select “New Window”) and ...
Notes for The Longevity Seekers
Notes for The Longevity Seekers

... Researchers clashed with evolutionary theorists who claimed that if a gene prolonged life, it would do other things that were deleterious. There was also the problem of how to prescribe a drug to “those at risk” when everyone is a risk for aging! The ethics of longevity research was discussed in Was ...
Genetics - TeacherWeb
Genetics - TeacherWeb

... units determining heritable characteristics. This is now known as an ____________ ...
Gene Regulation in Eukaryotes
Gene Regulation in Eukaryotes

... Another example: In mammals (mice, humans, pigs), only the allele for insulin-like growth factor-2 (IGF2) inherited from one's father is active; that inherited from the mother is not — a phenomenon called imprinting. The mechanism: the mother's allele has an insulator between the IGF2 promoter and e ...
4/23/2014 Difference Between DNA and Genes | Difference
4/23/2014 Difference Between DNA and Genes | Difference

... • Categorized under Science | Difference Between DNA and Genes The terms gene and DNA are often used to mean the same. However, in reality, they stand for very different things. So, next time you want to blame your baldness on your father and don’t know whether to berate your genes or your DNA, take ...
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Ridge (biology)

Ridges (regions of increased gene expression) are domains of the genome with a high gene expression; the opposite of ridges are antiridges. The term was first used by Caron et al. in 2001. Characteristics of ridges are:Gene denseContain many C and G nucleobasesGenes have short intronshigh SINE repeat densitylow LINE repeat density↑ 1.0 1.1
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