Article Comparative Genomics as a Time Machine: How Relative
... Using a phylogenetic model of evolution after genome duplication (i.e., polyploidy) and 12 yeast genomes with a shared genome duplication, I show that the loss of duplicate genes after that duplication occurred in three phases. First, losses that occurred immediately after the event were biased towa ...
... Using a phylogenetic model of evolution after genome duplication (i.e., polyploidy) and 12 yeast genomes with a shared genome duplication, I show that the loss of duplicate genes after that duplication occurred in three phases. First, losses that occurred immediately after the event were biased towa ...
Gene set enrichment analysis (GSEA)
... higher mean expression than DMSO group. Similarly, positive β2 means that the 3-week group has higher mean expression than the 1-day group. ...
... higher mean expression than DMSO group. Similarly, positive β2 means that the 3-week group has higher mean expression than the 1-day group. ...
News Features Human genome sequences — a potential treasure
... made its data freely available to the public via the Internet on a daily basis. Its work was undertaken by about a thousand scientists in six countries, including one developing country, China. The other sequence and its analysis were published by the US commercial company Celera Genomics in Science ...
... made its data freely available to the public via the Internet on a daily basis. Its work was undertaken by about a thousand scientists in six countries, including one developing country, China. The other sequence and its analysis were published by the US commercial company Celera Genomics in Science ...
Using Animal Models to Understand Aging
... Environmental factors such as diet have a huge impact on aging. Reducing levels of food by 30—50% has been shown to significantly extend lifespan and reduce age–related diseases in mice and rats. This led to the theory of Caloric Restriction (CR) – that by manipulating the nutrition of the organis ...
... Environmental factors such as diet have a huge impact on aging. Reducing levels of food by 30—50% has been shown to significantly extend lifespan and reduce age–related diseases in mice and rats. This led to the theory of Caloric Restriction (CR) – that by manipulating the nutrition of the organis ...
the smallest dinoflagellate genome is yet to be found: a comment on
... and throughput higher. Any hope for the near future would rest with the possibility of bringing into culture a picoplanktonic dinoflagellate whose genome is at least 10-fold smaller, if such taxon indeed exists. Alternatively, isolation and sequencing of a single megabasesized chromosome would be a ...
... and throughput higher. Any hope for the near future would rest with the possibility of bringing into culture a picoplanktonic dinoflagellate whose genome is at least 10-fold smaller, if such taxon indeed exists. Alternatively, isolation and sequencing of a single megabasesized chromosome would be a ...
ppt
... • 1.2 million protein-coding genes (10X more than previously in protein database) • 69,901 conserved open reading frames with no assignable function • 60,000 16S sequences, 148 of which are at least 3% different from previously known sequence ...
... • 1.2 million protein-coding genes (10X more than previously in protein database) • 69,901 conserved open reading frames with no assignable function • 60,000 16S sequences, 148 of which are at least 3% different from previously known sequence ...
chapter 1 - VU-DARE
... species and within species and thus to analyze variation in a genome-wide manner. It also has become possible to analyze genomes from less-investigated invertebrate species that are not considered to be classical genetic models. This has given rise to new insights into the tree of life, into the nat ...
... species and within species and thus to analyze variation in a genome-wide manner. It also has become possible to analyze genomes from less-investigated invertebrate species that are not considered to be classical genetic models. This has given rise to new insights into the tree of life, into the nat ...
Document
... molecules that exist in bacteria and in the nuclei of some eukaryotic cells. They can replicate independently of the host cell. The size of plasmids ranges from a few kb to near 100 kb Can hold up to 10 kb fragments Plasmids have an origin of replication, antibiotic resistance genes as markers, and ...
... molecules that exist in bacteria and in the nuclei of some eukaryotic cells. They can replicate independently of the host cell. The size of plasmids ranges from a few kb to near 100 kb Can hold up to 10 kb fragments Plasmids have an origin of replication, antibiotic resistance genes as markers, and ...
Branchiootorenal (BOR/BOS) Spectrum Disorder Panel
... of individuals with BOR/BOS have an identified mutation in EYA1. Approximately 10% of individuals with BOR/BOS will have a chromosomal rearrangement in the region of the EYA1 gene, which will not be detected by our test methodology. FISH and deletion duplication analysis may be indicated in the pres ...
... of individuals with BOR/BOS have an identified mutation in EYA1. Approximately 10% of individuals with BOR/BOS will have a chromosomal rearrangement in the region of the EYA1 gene, which will not be detected by our test methodology. FISH and deletion duplication analysis may be indicated in the pres ...
The Title of the Article
... which results from a recently published Type 2 Diabetes association study are used to identify potential hypotheses. Introduction Identifying, confirming, and validating candidate genes in complex diseases is a daunting task. A genome-wide association study, in particular, can generate an extremely ...
... which results from a recently published Type 2 Diabetes association study are used to identify potential hypotheses. Introduction Identifying, confirming, and validating candidate genes in complex diseases is a daunting task. A genome-wide association study, in particular, can generate an extremely ...
Dr. Sinan Bahjat MBCh.B., M.Sc., FIBMSL1
... A gene can exist in more than one form. Organisms inherit two alleles for each trait. When gametes are produced (by meiosis), allele pairs separate leaving each cell with a single allele for each trait. When the two alleles of a pair are different, one is dominant and the other is recessive. ...
... A gene can exist in more than one form. Organisms inherit two alleles for each trait. When gametes are produced (by meiosis), allele pairs separate leaving each cell with a single allele for each trait. When the two alleles of a pair are different, one is dominant and the other is recessive. ...
Complementation
... caused by one or the other X chromosome being inactivated. White fur results from the effect of another gene. ...
... caused by one or the other X chromosome being inactivated. White fur results from the effect of another gene. ...
Whole genome sequencing - Center for Biological Sequence Analysis
... Most genomes are enormous (e.g 108 base pair in case of human). So it is impossible to be sequenced directly! This is called LargeScale Sequencing ...
... Most genomes are enormous (e.g 108 base pair in case of human). So it is impossible to be sequenced directly! This is called LargeScale Sequencing ...
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate
... descent, and Native American descent. Although when left untreated, the syndrome is usually not fatal. However, understandably, such orofacial clefts usually results in self-esteem issues later in life. Studies of genetic and/or teratogenic causes of CL/P during the pre-natal period can benefit the ...
... descent, and Native American descent. Although when left untreated, the syndrome is usually not fatal. However, understandably, such orofacial clefts usually results in self-esteem issues later in life. Studies of genetic and/or teratogenic causes of CL/P during the pre-natal period can benefit the ...
Concept 3 - Ms DeBeaudrap Science
... blueprint of life for each multicellular organism tells the cell what to do and what to form where 2. What is a chromosome? Explain its function. a structure in which DNA is arranged and along which genes are found 3. What is an allele? Explain its function. a possible form of a gene varia ...
... blueprint of life for each multicellular organism tells the cell what to do and what to form where 2. What is a chromosome? Explain its function. a structure in which DNA is arranged and along which genes are found 3. What is an allele? Explain its function. a possible form of a gene varia ...
Patterns of Inheritance
... A gene is the specific portion of chromosome that has the complete information to synthesize … a specific protein ...
... A gene is the specific portion of chromosome that has the complete information to synthesize … a specific protein ...
Emphasis mine – fdu. ↓ Genes lie on
... Morgan and Bridges – genes lie on chromosomes (1910-1915). Bateson and Sturtevant (1906-15) – some genes appear to be physically linked; the nature of this linkage is the following: genes are arranged on a chromosome in a linear order, at particular distances from each other. McClintock and Stern (1 ...
... Morgan and Bridges – genes lie on chromosomes (1910-1915). Bateson and Sturtevant (1906-15) – some genes appear to be physically linked; the nature of this linkage is the following: genes are arranged on a chromosome in a linear order, at particular distances from each other. McClintock and Stern (1 ...
EMS-treated culture
... • 5,000 cells carry a mutation, – or, one mutation every ~ 1,000 bases (across a colony), – or, a mutation in about every gene. ...
... • 5,000 cells carry a mutation, – or, one mutation every ~ 1,000 bases (across a colony), – or, a mutation in about every gene. ...
Transgenic Corn
... The Agrobacterium tumefacien bacteria is a vector, which means it enables the transportation of foreign genes into plants. This bacteria contains a tumor inducing (Ti) plasmid. The T region of the plasmid becomes incorporated in the plant cell. 1. A foreign gene is inserted into the T region of ...
... The Agrobacterium tumefacien bacteria is a vector, which means it enables the transportation of foreign genes into plants. This bacteria contains a tumor inducing (Ti) plasmid. The T region of the plasmid becomes incorporated in the plant cell. 1. A foreign gene is inserted into the T region of ...
Cystic Fibrosis – This results in a malformed ion channel, causing
... Every year in Illinois, up to 500 babies are born with hearing loss. Also, catching hearing difficulties early is important to that the affected child can receive the help they need from an early age. For these reasons, children born in Illinois are screened at birth for certain types of deafness or ...
... Every year in Illinois, up to 500 babies are born with hearing loss. Also, catching hearing difficulties early is important to that the affected child can receive the help they need from an early age. For these reasons, children born in Illinois are screened at birth for certain types of deafness or ...
05. Chromosomal theory of heredity Genetics of sex
... Is there a special pattern of inheritance for genes located on the X chromosome or the Y chromosome? Because these chromosomes determine sex, genes located on them are said to be sexlinked genes Many sex-linked genes are found on the X chromosome More than 100 sex-linked genetic disorders have now b ...
... Is there a special pattern of inheritance for genes located on the X chromosome or the Y chromosome? Because these chromosomes determine sex, genes located on them are said to be sexlinked genes Many sex-linked genes are found on the X chromosome More than 100 sex-linked genetic disorders have now b ...
Bacteria and Viruses Bacterial Cells Bacterial Genome Bacterial
... – 1/1000 as much as eukaryotes – 100x more than viruses ...
... – 1/1000 as much as eukaryotes – 100x more than viruses ...