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BITC1311 Intro to Biotechnology Name
BITC1311 Intro to Biotechnology Name

... 2. The earliest recorded forms of biotechnology date from 2000 BC with the use of fermentations and selective breeding of domesticated livestock. Describe some applications of each of these forms of early biotechnology. 3. Antibiotics were discovered in 1928 by Alexander Fleming. How are antibiotics ...
DNA Testing Is Changing Our Thinking About Belgian Shepherd
DNA Testing Is Changing Our Thinking About Belgian Shepherd

... many are no longer accurate. Using DNA swabs from various Belgians (Groenendaels, Laekenois, Malinois, and Tervuren), submitted from owners in Canada, U.S.A., and Holland, Dr. Schmutz and her team were able to pinpoint coat color genes carried by the individual specimens tested. Some were surprises, ...
F 1
F 1

... VIII, the clotting factor, is carried on the X chromosome. The affected males inherited their single X chromosome from their mothers—if the mutated form of the gene was present, they would develop the disease. Daughters would inherit a normal X chromosome as well and would not express the recessive ...
When to use reverse genetics?
When to use reverse genetics?

... Why cannot forward genetics find mutants carrying mutations in all genes? 1. Redundancy 2. Lethal mutations 3. Subtle or not obvious phenotypes ...
LPN1 report University of Minnesota
LPN1 report University of Minnesota

... that appear to contain other PN loci have failed to find other LPN mutations. So, although our whole genome scans of PN cases that are not accounted for by the LPN1 mutation still suggests two different chromosomal locations that appear of interest, we are no closer to finding the mutations. It coul ...
Human Chromosomes and Genes
Human Chromosomes and Genes

... The remaining pair of human chromosomes consists of the sex chromosomes, X and Y. Females have two X chromosomes, and males have one X and one Y chromosome. In females, one of the X chromosomes in each cell is inactivated and known as a Barr body. This ensures that females, like males, have only one ...
Chapter 15 - ShoultzScience
Chapter 15 - ShoultzScience

... 5-bromouracil pairs with thymine but rearranges to a form that pairs with cytosine at the next DNA replication: an A—T pair becomes a G—C pair.  Chemicals may add hydrocarbon groups or remove amino groups from DNA bases.  Tobacco smoke contains a number of chemical carcinogens. ...
Neural Identity
Neural Identity

SNP Discovery by sequencing 1000 genomes
SNP Discovery by sequencing 1000 genomes

... The HapMap has become a key resource for researchers to use to find genes affecting health, disease, and responses to drugs and environmental factors. Phase 3 has been completed and there >6 million SNPs defined. ...
TASSEL
TASSEL

...  One line from one taxon only.  Has to be as diverse it could be – Extensive recombination history.  50 - 150 markers in a non random mated population – Good statistical power!! ...
Review: Genetics
Review: Genetics

... is responsible for on each chromosome. • Since no two individuals have the exact same genome, biologist can use DNA fingerprinting to identify individuals – For example, if blood, sperm or hair is found at a crime scene, DNA from the tissue can be cut using restriction enzymes and fragments can be s ...
Supplementary Material Deep sequencing of the human
Supplementary Material Deep sequencing of the human

... Supplementary Figure S3. The expression patterns of housekeeping genes in different human tissues. The housekeeping gene expression levels of the three retina samples, the peripheral retina (pRetina) and the macular retina (mRetina) and the reference tissues [human fetal RPE (fRPE), brain, colon, li ...
Assembly Validation - felixeye.github.io
Assembly Validation - felixeye.github.io

... Assessing genome assembly and annotation completeness with Benchmarking Universal Single-Copy Orthologs Similar idea based on aa or nt alignments of •Golden standard genes from own species •Transcriptome assembly •Reference species protein set Use e.g. GSNAP/BLAT (nt), exonerate/SCIPIO (aa) ...
Info-PubMed
Info-PubMed

... Info-PubMed (1) Info-PubMed provides information from Medline on protein-protein interactions. (2) Given the name of a gene or protein, it shows a list of the names of other genes/proteins which co-occur in sentences from Medline, along with the frequency of co-occurrence. (3)Co-occurrence of two p ...
Ge´nie: literature-based gene prioritization at multi genomic scale
Ge´nie: literature-based gene prioritization at multi genomic scale

... to screen for genes associated with particular properties, which can then be further used to design new experiments or to prioritize analysis (1). Classically, the literature dealing with genes, as stored in the MEDLINE database of biomedical references (2), has been used to do this prioritization ( ...
expression of key genes related to unspecific
expression of key genes related to unspecific

... Introduction – RT-qPCR • reliable, sensitive and accurate • the method of choice for the quantitative detection of mRNA gene expression levels • frequently applied to measure how various compounds or experimental conditions affect organisms at the molecular level ...
Gene expression
Gene expression

... –  results in the production of more than one polypeptide from the same gene, and –  may be common in humans. ...
Patterns of inheritance
Patterns of inheritance

... Recessive traits and alleles - the offspring will only get the trait if both parents contribute the trait. These traits can be carried in the persons genes, without appearing in the person. They are represented by a lower case letter (a, for example) – Eg, a dark-haired person may have one gene for ...
Lateral gene transfer and the nature of bacterial innovation
Lateral gene transfer and the nature of bacterial innovation

The Dolan DNA Learning Center at Cold Spring Harbor Laboratory
The Dolan DNA Learning Center at Cold Spring Harbor Laboratory

... 4. What role does the repressor (product of the lacI gene) play in control of transcription of the lac operon? It is inhibits transcription when physically bound to the regulatory region. 5. What effect does the inducer have on the lacI gene product? It has an allosteric effect on the repressor, cha ...
Understanding Inheritance A. 1.
Understanding Inheritance A. 1.

... 2. Mendel’s factors are parts of chromosomes, and each cell in the offspring contains chromosomes from both ...
HumanGeneticDisorders
HumanGeneticDisorders

... In 1945, Neil Dorhoff and Marie Shoo, both tongue rollers, had a whirlwind affair and married. They had three children, Steve, Maureen, and Tom. Steve was always the favorite son because he could roll his tongue, while Maureen and Tom could not. Unfortunately, Tom died in a bizarre gardening acciden ...
AP Biology Study Guide
AP Biology Study Guide

... and polygenic inheritance. Provide an example of each. ...
Gene Section TFEB (transcription factor EB) Atlas of Genetics and Cytogenetics
Gene Section TFEB (transcription factor EB) Atlas of Genetics and Cytogenetics

... Published in Atlas Database: May 2004 Online updated version: http://AtlasGeneticsOncology.org/Genes/TFEBID531.html DOI: 10.4267/2042/38098 This work is licensed under a Creative Commons Attribution-Noncommercial-No Derivative Works 2.0 France Licence. © 2004 Atlas of Genetics and Cytogenetics in On ...
Chapter 4: Epigenesis and Genetic Regulation
Chapter 4: Epigenesis and Genetic Regulation

... about 5,000 cells, one of these chromosomes is randomly deactivated in all the cells. Once a chromosome is inactive in a given cell, all its daughter cells will have the same chromosome deactivated. That is, if “cell number 23” has the paternal X deactivated, then all descendants of cell 23 will als ...
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Minimal genome

The concept of minimal genome assumes that genomes can be reduced to a bare minimum, given that they contain many non-essential genes of limited or situational importance to the organism. Therefore, if a collection of all the essential genes were put together, a minimum genome could be created artificially in a stable environment. By adding more genes, the creation of an organism of desired properties is possible. The concept of minimal genome arose from the observations that many genes do not appear to be necessary for survival. In order to create a new organism a scientist must determine the minimal set of genes required for metabolism and replication. This can be achieved by experimental and computational analysis of the biochemical pathways needed to carry out basic metabolism and reproduction. A good model for a minimal genome is Mycoplasma genitalium, the organism with the smallest known genome. Most genes that are used by this organism are usually considered essential for survival; based on this concept a minimal set of 256 genes has been proposed.
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