Chapter 6: Artificial Evolution
... trying to mimic or model aspects of the biological system under examination. The other main goal is to use methods from artificial evolution as optimization tools, or more generally as design methods. In many areas, evolutionary algorithms have proved highly useful, especially for “hard” problems. I ...
... trying to mimic or model aspects of the biological system under examination. The other main goal is to use methods from artificial evolution as optimization tools, or more generally as design methods. In many areas, evolutionary algorithms have proved highly useful, especially for “hard” problems. I ...
Bridges, Calvin. Triploid intersexes in Drosophila melanogaster
... in triplicate and the X- in duplicate, but they might possess three or two fourth-chromosomes, and have or lack a Y-chromosome, so that four sub-types of intersex constitution were found. About ten per cent. of the daughters from the original culture, when tested, produced in turn intersexes and fur ...
... in triplicate and the X- in duplicate, but they might possess three or two fourth-chromosomes, and have or lack a Y-chromosome, so that four sub-types of intersex constitution were found. About ten per cent. of the daughters from the original culture, when tested, produced in turn intersexes and fur ...
S13Set #1
... between mitosis and meiosis. ❖ Problem 4 Many plants are polyploid, which means that they have more than two sets of chromosomes. Seedless strains of bananas and watermelon are triploid (3n) having 3 copies of each chromosome. Such triploids rarely produce viable seeds because the gametes produced d ...
... between mitosis and meiosis. ❖ Problem 4 Many plants are polyploid, which means that they have more than two sets of chromosomes. Seedless strains of bananas and watermelon are triploid (3n) having 3 copies of each chromosome. Such triploids rarely produce viable seeds because the gametes produced d ...
Supplementary Information (doc 63K)
... was used to test the newly designed RT-MLPA. TP53 and ATM molecular status was determined using FISH and sequencing. Only samples with biallelic TP53 (TP53 mutation + 17p deletion) and biallelic ATM (ATM mutation + 11q deletion) defects were included. In addition, TP53-mutant CLL samples were to a l ...
... was used to test the newly designed RT-MLPA. TP53 and ATM molecular status was determined using FISH and sequencing. Only samples with biallelic TP53 (TP53 mutation + 17p deletion) and biallelic ATM (ATM mutation + 11q deletion) defects were included. In addition, TP53-mutant CLL samples were to a l ...
Searching for microsatellite mutations in coding regions in
... consequences requires further study. By contrast, human tumors that do not exhibit the MSI phenotype (0/67 tumors) appear to have rarely mutated repeat sequences in the open reading frame. Thus, if an open reading frame repeat sequence was found that was frequently mutated in MSI7 tumors it would qu ...
... consequences requires further study. By contrast, human tumors that do not exhibit the MSI phenotype (0/67 tumors) appear to have rarely mutated repeat sequences in the open reading frame. Thus, if an open reading frame repeat sequence was found that was frequently mutated in MSI7 tumors it would qu ...
Gene Transfer
... “looping out” to reconstitute a plasmid carrying the antibiotic resistance gene. As maize is usually transformed by biolistics (DNA coated particle bombardment), the entire linearized parental plasmid may be integrated into the plant DNA and could therefore be excised and ligated to form a replicati ...
... “looping out” to reconstitute a plasmid carrying the antibiotic resistance gene. As maize is usually transformed by biolistics (DNA coated particle bombardment), the entire linearized parental plasmid may be integrated into the plant DNA and could therefore be excised and ligated to form a replicati ...
a meiotic mutation causing partial male sterility in a corn silage hybrid
... In higher plants, male sterility results from many individual developmental events that specify the ontogeny of the male organs. Mutations that impair any step in these processes give rise to defective stamen or pollen development, causing male sterility. Male sterility can be controlled by nuclear ...
... In higher plants, male sterility results from many individual developmental events that specify the ontogeny of the male organs. Mutations that impair any step in these processes give rise to defective stamen or pollen development, causing male sterility. Male sterility can be controlled by nuclear ...
Domestication genes in plants
... The genetic basis of the evolution of non-shattering Non-shattering is often regarded as the hallmark of domestication in most seed crops because it renders a plant species primarily dependent on humans for survival and propagation: • rice gene sh4 (similar to the genes encoding MYBlike transcripti ...
... The genetic basis of the evolution of non-shattering Non-shattering is often regarded as the hallmark of domestication in most seed crops because it renders a plant species primarily dependent on humans for survival and propagation: • rice gene sh4 (similar to the genes encoding MYBlike transcripti ...
miRNA
... the protocol of enrichment analysis There is a tendency for two directly interacting proteins participate in the same biological process or share the same molecular function. Let a miRNA targeting pathway denoted by miRNA – TG – L1 – L2. We propose to rank the pathway result according to the number ...
... the protocol of enrichment analysis There is a tendency for two directly interacting proteins participate in the same biological process or share the same molecular function. Let a miRNA targeting pathway denoted by miRNA – TG – L1 – L2. We propose to rank the pathway result according to the number ...
AP_Advanced_Genetics_2015
... Sickle cell anemia is caused by the mutation of a single base pair in the gene for hemoglobin. This mutation results in hemoglobin molecules that form long chains in low-oxygen settings and stretch the blood cells into their characteristic sickled shape. What would the result be if a different base ...
... Sickle cell anemia is caused by the mutation of a single base pair in the gene for hemoglobin. This mutation results in hemoglobin molecules that form long chains in low-oxygen settings and stretch the blood cells into their characteristic sickled shape. What would the result be if a different base ...
Chapter 18 Regulation of Gene Expression Multiple-Choice
... genome and the genomes of many other multicellular eukaryotes. There was surprise expressed by many that the number of protein-coding sequences is much smaller than they had expected. Which of the following accounts for most of the rest? A) ʺjunkʺ DNA that serves no possible purpose B) rRNA and tRNA ...
... genome and the genomes of many other multicellular eukaryotes. There was surprise expressed by many that the number of protein-coding sequences is much smaller than they had expected. Which of the following accounts for most of the rest? A) ʺjunkʺ DNA that serves no possible purpose B) rRNA and tRNA ...
The Drosophila Gene Disruption Project: Progress
... have been described (Thibault et al. 2004). These lines probably do not represent a completely random collection of insertions, because some lines disrupting major hotspots appear to have been culled by Exelixis. However, we found many cases where at least two lines bearing identical piggyBac insert ...
... have been described (Thibault et al. 2004). These lines probably do not represent a completely random collection of insertions, because some lines disrupting major hotspots appear to have been culled by Exelixis. However, we found many cases where at least two lines bearing identical piggyBac insert ...
Horizontal Transfer of DNA From GM Crops to Bacteria and to
... transformation in some bacteria requires that at least 2 copies of a plasmid, or at least fragments of the 2nd copy, must be introduced simultaneously into the same bacterial cell so that overlapping segments are available to regenerate the plasmid in a natural transformation (Salyers 1998). Given t ...
... transformation in some bacteria requires that at least 2 copies of a plasmid, or at least fragments of the 2nd copy, must be introduced simultaneously into the same bacterial cell so that overlapping segments are available to regenerate the plasmid in a natural transformation (Salyers 1998). Given t ...
Documentation for Candidate Gene Prioritization
... This script retrieves the map of sequence tagged sites (useful for microsatellite markers) from the HapMap Project. This script also retrieves dbSNP build 124 from the HapMap Project. Note that this file is quite large, and takes hours to load into memory. For this reason, this part of the code is c ...
... This script retrieves the map of sequence tagged sites (useful for microsatellite markers) from the HapMap Project. This script also retrieves dbSNP build 124 from the HapMap Project. Note that this file is quite large, and takes hours to load into memory. For this reason, this part of the code is c ...
Slide 1
... The genetic basis of the evolution of non-shattering Non-shattering is often regarded as the hallmark of domestication in most seed crops because it renders a plant species primarily dependent on humans for survival and propagation: • rice gene sh4 (similar to the genes encoding MYBlike transcripti ...
... The genetic basis of the evolution of non-shattering Non-shattering is often regarded as the hallmark of domestication in most seed crops because it renders a plant species primarily dependent on humans for survival and propagation: • rice gene sh4 (similar to the genes encoding MYBlike transcripti ...
Chapter 9, 10, and 11
... b. Females only mate once and lay hundreds of eggs. c. The fruit fly generation time is short, allowing rapid experiments. 6. Fruit flies have an XY sex chromosome system similar to the human system; experiments can be correlated to the human situation. a. Newly discovered mutant male fruit flies ha ...
... b. Females only mate once and lay hundreds of eggs. c. The fruit fly generation time is short, allowing rapid experiments. 6. Fruit flies have an XY sex chromosome system similar to the human system; experiments can be correlated to the human situation. a. Newly discovered mutant male fruit flies ha ...
Document
... large (1-14kb) repeated sequence. There is no pattern to the sequences (including genes) that are duplicated in the mitochondrial genomes of different plants. ...
... large (1-14kb) repeated sequence. There is no pattern to the sequences (including genes) that are duplicated in the mitochondrial genomes of different plants. ...
bioinformatics
... ancestor. Two such segments are called segmental homologs (SH). When dealing with an incompletely mapped genome, knowing that two segments are homologous is useful in that it suggests that other (unmapped) features within those same segments may have homologous counterparts in the opposite segment. ...
... ancestor. Two such segments are called segmental homologs (SH). When dealing with an incompletely mapped genome, knowing that two segments are homologous is useful in that it suggests that other (unmapped) features within those same segments may have homologous counterparts in the opposite segment. ...
On-the-fly Link Generation for Workflows in Biology
... data source, sends a proper query and processes its output. Therefore, it becomes a serious obstacle to the integration of distributed heterogeneous data sources. To solve this problem, DNA Data Bank of Japan (DDBJ) provides Web-based systems for biological analysis, called Web APIs for biology (WAB ...
... data source, sends a proper query and processes its output. Therefore, it becomes a serious obstacle to the integration of distributed heterogeneous data sources. To solve this problem, DNA Data Bank of Japan (DDBJ) provides Web-based systems for biological analysis, called Web APIs for biology (WAB ...
Performance Comparison of Two Gene Set Analysis Methods for
... pronounced with low-scoring genes, the high-scoring genes suffer little. Since the mean of all gene scores would also decrease by using the second-best p-values compared to the use of the best p-values, the resulting Z-statistic for a gene set that is composed of high-scoring genes would then increa ...
... pronounced with low-scoring genes, the high-scoring genes suffer little. Since the mean of all gene scores would also decrease by using the second-best p-values compared to the use of the best p-values, the resulting Z-statistic for a gene set that is composed of high-scoring genes would then increa ...
Epigenetics and Inheritance
... this second group of histones and link to the third group of histones via linker DNA, eventually forming a long strand of chromatin which is called “beads on a string” and which is 11 nm in diameter. (5) The second level of organization is the coiling of the “beads on a string” into a helical struc ...
... this second group of histones and link to the third group of histones via linker DNA, eventually forming a long strand of chromatin which is called “beads on a string” and which is 11 nm in diameter. (5) The second level of organization is the coiling of the “beads on a string” into a helical struc ...
mendelian genetics
... 1. _______________________________-the passage of traits from parents to offspring 2. _______________________________-the scientific study of heredity 3. _______________________________-was an Austrian monk; became known as the “Father of Genetics” by doing pollination experiments with _____________ ...
... 1. _______________________________-the passage of traits from parents to offspring 2. _______________________________-the scientific study of heredity 3. _______________________________-was an Austrian monk; became known as the “Father of Genetics” by doing pollination experiments with _____________ ...
MITOCHONDRIAL INHERITANCE
... the faulty mitochondrial genes to a child and if, or how severely, the child would be affected • While it is possible to test for the presence or absence of some faulty mitochondrial genes and their products during pregnancy, the result may be difficult to interpret • Whether symptoms of the condi ...
... the faulty mitochondrial genes to a child and if, or how severely, the child would be affected • While it is possible to test for the presence or absence of some faulty mitochondrial genes and their products during pregnancy, the result may be difficult to interpret • Whether symptoms of the condi ...
draft - University of Michigan
... ChIP-chip and ChIP-seq for TFs and chromatin marks, and microarray and RNA-seq measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes for X-linked and autosomal TFs (Figure 5A). For the 213 TFs included in our set of 48 ...
... ChIP-chip and ChIP-seq for TFs and chromatin marks, and microarray and RNA-seq measures of gene expression (Marbach et al. 2012). Using the edges in this network, we compared the proportion of X-linked target genes for X-linked and autosomal TFs (Figure 5A). For the 213 TFs included in our set of 48 ...