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Phylogeny slides
Phylogeny slides

... “Optimal” depends on multiple alignment scoring method No known (correct) efficient algorithms for this problem ...
Glycemia and Wt Mngt. Olz
Glycemia and Wt Mngt. Olz

... extent greater than  is equal to the proportion of genes in the remainder of the genome that are differentially expressed. ...
19. IMG-ER Curation Environment
19. IMG-ER Curation Environment

... EC number and PUBMED ID – see explanation Notes are free text (goes to “note” in GenBank submission) Gene symbol is “gene name” – 4 letter abbreviation; goes to “gene” in GenBank submission ...
Genomics of sensory systems - University of Maryland
Genomics of sensory systems - University of Maryland

Heredity
Heredity

... store this information in databases, improve tools for data analysis, transfer related technologies to the private sector, and address the ethical, legal, and social issues (ELSI) that may arise from the project. ...
I. Comparing genome sequences
I. Comparing genome sequences

... • Orthologous sequences = homologous sequences separated by a speciation event (e.g., human HOXA and mouse Hoxa) • Paralogous sequences = homologous sequences separated by gene duplication (e.g., human HOXA and human HOXB) ...
Why the long neck?
Why the long neck?

... the U.K., and the U.S. came up with a list of 17,210 giraffe and 17,048 okapi genes. Comparing those sequences, the team found that the giraffe’s long neck is likely a result of mutations in two sets of protein-coding genes—one controlling gene expression patterns during limb development, the other ...
Mycoplasma genitalium
Mycoplasma genitalium

... do? What is the function of the protein? – Search database for similar sequences – How does sequence compare to sequences for proteins of known function? – Use computer to search for functional motifs. • Various proteins that do the same thing have similar structural elements. • Example: transcripti ...
keeSeek: searching distant non-existing words in genomes for PCR
keeSeek: searching distant non-existing words in genomes for PCR

... the search is ungapped, allowing the implementation of an algorithm linear in space and time (see Supplementary File S1.1 for details). We encode both the reference and the k-mer using a compressed binary representation in blocks of 64 bits and, by using a sliding window, each candidate is then comp ...
GenesEnv
GenesEnv

... from Yarrow plant clones grew differently at three different altitudes  Cuttings from one plant grew tall at the lowest and the highest elevation  But a third cutting remained short at midelevation  Even though these plants were genetically identical, their phenotypes differed in different enviro ...
Problem 3: Why do pre-mRNAs get smaller during RNA processing?
Problem 3: Why do pre-mRNAs get smaller during RNA processing?

... Promoters for eukaryotic mRNA genes: A. are more complex than prokaryotic promoters B. can require binding of multiple transcription factors to form a transcription complex C. have specific DNA sequences such as the "TATA" box that are recognized by proteins D. are the stretches of DNA to which RNA ...
Q $100 Q $200 Q $300 Q $400 Q $500 Q $100 Q $100 Q $100 Q
Q $100 Q $200 Q $300 Q $400 Q $500 Q $100 Q $100 Q $100 Q

... shows traits of a family, similar to a family tree. ...
Genetics Study Guide
Genetics Study Guide

... 13. What does each gene have instructions for making? A protein 14. When a plant fertilizes itself, it is called self-pollinating plant. 15. What is it called when cells are copied with half the number of chromosomes? Meiosis 16. What factors have an influence on your traits? Single genes, multiple ...
Chapter Notes
Chapter Notes

... Trait: a particular feature that can vary in size or form from individual to individual within a species. A trait is inherited from biological parents. Heredity: the process through which patterns of traits are passed on from an individual to its offspring. ...
Human Genome Case Study
Human Genome Case Study

... Experts have tried to sort out those agendas for years. over the fact that companies may make money (from the This year the federal government strengthened its data). How do you do (research) without money?” regulations protecting human research subjects, hoping to John Kilyk Jr., managing partner w ...
Coevolution --- viruses may have evolved along with cells
Coevolution --- viruses may have evolved along with cells

... Viral Genomes & Replication --- compared to other replicating forms most viruses have very small genomes (25 – 250 Kbp) ...
MODULE 7: REGULATION OF GENE EXPRESSION DURING
MODULE 7: REGULATION OF GENE EXPRESSION DURING

... What are embryonic stem cells? Where are they present in a mammalian embryo? How can we culture them in vitro without loss of their totipotency? It is now possible to induce differentiated cells to become pluripotent stem cells by the introduction of a few genes. Who demonstrated this phenomenon fir ...
and MUTYH mutation negative FAP and AFAP patients
and MUTYH mutation negative FAP and AFAP patients

... Two families with AFAP with two and three patients respectively were analyzed with the 1.0 HuEx arrays from Affymetrix. The exon-arrays include over 40 probes for each gene and four probes (one probeset) for every exon for all well annotated genes. The robust multi-array analysis (RMA) algorithm was ...
Genome Questions
Genome Questions

... 1. Prior to 1955, scientists believed humans had how many nuclear chromosomes? 2. Humans normally have how many nuclear chromosomes? 3. Which ape is closest to humans genetically, sharing 98% of our genetic code? 4. What is the process by which genes change their sequences? 5. Genes are recipes for ...
Genes and Variation
Genes and Variation

... i.e. no matter how many times you shuffle a deck of cards, the probability of drawing a particular card will remain the same. ...
The human genome
The human genome

... There are two kinds of distance metric for chromosome. Physical distances are measured in terms of number of base pairs (abbreviated as bp) Between two points. The units for physical distances are bp and kb (1000 bp). Genetic distances are defined as the expected numbers of crossovers between two p ...
Population Genetics Vocabulary - Liberty Union High School District
Population Genetics Vocabulary - Liberty Union High School District

... Changes in the gene pool of a population due to an introduction of genes from another gene pool, such as ...
detailed DNA presentation
detailed DNA presentation

... Nucleotides aka bases ...
Recombinant DNA - Westwind Alternate School
Recombinant DNA - Westwind Alternate School

... Recombinant DNA - DNA from a plant or animal cell is removed and a piece cut out - That DNA is inserted into the genome of another cell - once inserted, that DNA will be replicated, transcribed and translated as is the rest of the organism’s genome Applications  to insert human genes into other org ...
Viral genomes
Viral genomes

... for constructing proteins; exons are the regions that actually encode for the protein 2. Chromosome: physically separate microscopic units of DNA that comprise the genome 3. Genetics: the study of the patterns of inheritance of specific traits ...
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Genome evolution



Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.
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