parts
... The Nez Perce developed their selective breeding prowess through skills such as observation and patience. Modern geneticists use these same skills and others, as well as knowledge from biochemistry, statistical analysis, and other fields of inquiry. Geneticists analyze the data they collect, and the ...
... The Nez Perce developed their selective breeding prowess through skills such as observation and patience. Modern geneticists use these same skills and others, as well as knowledge from biochemistry, statistical analysis, and other fields of inquiry. Geneticists analyze the data they collect, and the ...
Whole Exome Re-Sequencing Implicates CCDC38 and
... airflow obstruction. Although the main risk factor for COPD is smoking, some individuals are observed to have a high forced expired volume in 1 second (FEV1) despite many years of heavy smoking. We hypothesised that these ‘‘resistant smokers’’ may harbour variants which protect against lung function ...
... airflow obstruction. Although the main risk factor for COPD is smoking, some individuals are observed to have a high forced expired volume in 1 second (FEV1) despite many years of heavy smoking. We hypothesised that these ‘‘resistant smokers’’ may harbour variants which protect against lung function ...
developing corn hybrids with new traits
... Proceedings of Indiana Crop Adviser Conference 2004 the recurrent parent). The recipient inbred is an elite inbred that is already used in commercial hybrids. The inbred line or plant that will be donating the gene is called the donor. The goal of backcrossing is to transfer the gene of interest fr ...
... Proceedings of Indiana Crop Adviser Conference 2004 the recurrent parent). The recipient inbred is an elite inbred that is already used in commercial hybrids. The inbred line or plant that will be donating the gene is called the donor. The goal of backcrossing is to transfer the gene of interest fr ...
The use of the twin model to investigate the genetics and
... twins are often discordant for diseases. Progress made in high throughput genotyping, transcriptomics, methylation studies and RNA sequencing are now showing that some of the unexplained ...
... twins are often discordant for diseases. Progress made in high throughput genotyping, transcriptomics, methylation studies and RNA sequencing are now showing that some of the unexplained ...
A natural recessive resistance gene against potato virus
... model to investigate recessive resistance because an unusually high frequency of occurrence of genes conferring recessive resistance to potyviruses has been observed (40% versus 20% for resistance against other viruses) (Provvidenti and Hampton, 1992). pvr2-mediated resistance of pepper (Capsicum sp ...
... model to investigate recessive resistance because an unusually high frequency of occurrence of genes conferring recessive resistance to potyviruses has been observed (40% versus 20% for resistance against other viruses) (Provvidenti and Hampton, 1992). pvr2-mediated resistance of pepper (Capsicum sp ...
Natural Selection and the Origin of Modules
... linkage disequilibrium between say the mutator locus and the genes which mutate to advantageous alleles. With recombination, the mutator gene can no longer ride to fixation on the coat tails of the other genes, a process that has been called “hitch hiking” (Maynard-Smith & Haigh, 1974). The reason i ...
... linkage disequilibrium between say the mutator locus and the genes which mutate to advantageous alleles. With recombination, the mutator gene can no longer ride to fixation on the coat tails of the other genes, a process that has been called “hitch hiking” (Maynard-Smith & Haigh, 1974). The reason i ...
WHITE PANICLE1, a Val-tRNA Synthetase
... only one open reading frame (ORF) encoding a putative Val-tRNA synthetase was different between wild type and wp1 in this region. We validated the mutation by digesting a derived cleaved amplified polymorphic sequence marker with NcoI (Fig. 3C). A single base transition (G to T) changed a Trp into a ...
... only one open reading frame (ORF) encoding a putative Val-tRNA synthetase was different between wild type and wp1 in this region. We validated the mutation by digesting a derived cleaved amplified polymorphic sequence marker with NcoI (Fig. 3C). A single base transition (G to T) changed a Trp into a ...
MHF1 plays Fanconi anaemia complementation group M protein
... of AtFANCM involvement in CL repair as its single mutants are not hypersensitive to CL-inducing agents (Knoll et al., 2012). In fact, CL repair differs considerably between plants and animals. Homologues of only a small number of the multiple human FANC genes can be found in plant genomes. Whereas t ...
... of AtFANCM involvement in CL repair as its single mutants are not hypersensitive to CL-inducing agents (Knoll et al., 2012). In fact, CL repair differs considerably between plants and animals. Homologues of only a small number of the multiple human FANC genes can be found in plant genomes. Whereas t ...
Flowering-Time Genes Modulate the Response to
... the transcriptional induction of LEAFY. These observations allow us to expand previously proposed models for the genetic control of flowering time. ...
... the transcriptional induction of LEAFY. These observations allow us to expand previously proposed models for the genetic control of flowering time. ...
Lampbrush Chromosomes of the Chicken
... as the Z chromosome. This chromosome has a striking landmark loop-bearing knob near one end that varies in morphology from a condensed knob to a very extended loop structure (Fig. 2). The opposite end of this chromosome often has a small distinct set of loops. In general, loops on this chromosome se ...
... as the Z chromosome. This chromosome has a striking landmark loop-bearing knob near one end that varies in morphology from a condensed knob to a very extended loop structure (Fig. 2). The opposite end of this chromosome often has a small distinct set of loops. In general, loops on this chromosome se ...
important update on the status of curly calf syndrome
... both theoretical and applicable knowledge in genomic science and technology. With government funding, it began the Livestock Genome Sequencing Initiative some five years ago, the first step in mapping and sequencing cattle (and swine) genomes. Dr. Beever has played an instrumental role in isolating ...
... both theoretical and applicable knowledge in genomic science and technology. With government funding, it began the Livestock Genome Sequencing Initiative some five years ago, the first step in mapping and sequencing cattle (and swine) genomes. Dr. Beever has played an instrumental role in isolating ...
Noise in eukaryotic gene expression
... galactose-mediated induction might therefore reflect the different molecular mechanisms by which galactose and ATc induce promoter activation, as shown by transient graded and binary responses, respectively (Fig. 1c). To determine whether the qualitative characteristics of the observed noise signatu ...
... galactose-mediated induction might therefore reflect the different molecular mechanisms by which galactose and ATc induce promoter activation, as shown by transient graded and binary responses, respectively (Fig. 1c). To determine whether the qualitative characteristics of the observed noise signatu ...
The ECF sigma factors of Streptomyces coelicolor A3(2)
... et al., 1998). It thus became clear that, in order to prevent an upward spiral of R synthesis, there must be a negative regulator in place to ensure that R is only switched on when necessary and to ensure that its activity is effectively switched off when the disulphide stress has been dealt with. ...
... et al., 1998). It thus became clear that, in order to prevent an upward spiral of R synthesis, there must be a negative regulator in place to ensure that R is only switched on when necessary and to ensure that its activity is effectively switched off when the disulphide stress has been dealt with. ...
Translation Section 1 From Genes to Proteins Chapter 10
... • Both prokaryotic and eukaryotic cells are able to regulate which genes are expressed and which are not, depending on the cell’s needs. • The piece of DNA that overlaps the promoter site and serves as the on-off switch is called an operator. ...
... • Both prokaryotic and eukaryotic cells are able to regulate which genes are expressed and which are not, depending on the cell’s needs. • The piece of DNA that overlaps the promoter site and serves as the on-off switch is called an operator. ...
Processing the RefSeq and CCDS Annotation Datasets Using the SAS System: Creation of Gene Reference
... (Line 45). Finally, we designate this region as the “Promoter”, but it could also be called “5’ genomic”. After we have acquired the promoter, the data step will now be within the region designated as the gene, that is beyond TXSTART (or TXEND, for minus-strand genes). The first and last exons are h ...
... (Line 45). Finally, we designate this region as the “Promoter”, but it could also be called “5’ genomic”. After we have acquired the promoter, the data step will now be within the region designated as the gene, that is beyond TXSTART (or TXEND, for minus-strand genes). The first and last exons are h ...
24 Recombination Hotspots in Nonallelic Homologous Recombination
... (3). Nonetheless, studies of both regions revealed that not all homologous sequences are equal and a “punctate” pattern of crossovers is revealed for both AHR and NAHR. In addition, homologous recombination is a process that can result in one of two outcomes: a crossover event or a gene conversion. ...
... (3). Nonetheless, studies of both regions revealed that not all homologous sequences are equal and a “punctate” pattern of crossovers is revealed for both AHR and NAHR. In addition, homologous recombination is a process that can result in one of two outcomes: a crossover event or a gene conversion. ...
Coin Child Lab – Answer Sheet
... but the recessive gene is hidden. Some genes are neither dominant nor recessive; they show incomplete dominance. There are also some traits that are passed down through polygenic inheritance. Polygenic inheritance occurs when one trait is determined by multiple genes, not just one gene (multiple pai ...
... but the recessive gene is hidden. Some genes are neither dominant nor recessive; they show incomplete dominance. There are also some traits that are passed down through polygenic inheritance. Polygenic inheritance occurs when one trait is determined by multiple genes, not just one gene (multiple pai ...
- Iranian Journal of Basic Medical Sciences
... of these isolates (1-5). This study aimed to survey the use of PCR-RFLP in comparison with proportional method for rapid detection of INH resistant M. tuberculosis strains. The resistance to INH was screened by proportional method in LJ medium and then INH MIC was determined in INH-resistant isolate ...
... of these isolates (1-5). This study aimed to survey the use of PCR-RFLP in comparison with proportional method for rapid detection of INH resistant M. tuberculosis strains. The resistance to INH was screened by proportional method in LJ medium and then INH MIC was determined in INH-resistant isolate ...
Why are most organelle genomes transmitted maternally?
... (sorting-out) of genetically distinct organelles (Box 1; Fig. 1), and the virtual absence of recombination [1, 2]. Due to the different evolutionary origins and inheritance modes of the genomes of the eukaryotic cell, severe evolutionary consequences arise: (i) Nuclear and organellar genomes differ ...
... (sorting-out) of genetically distinct organelles (Box 1; Fig. 1), and the virtual absence of recombination [1, 2]. Due to the different evolutionary origins and inheritance modes of the genomes of the eukaryotic cell, severe evolutionary consequences arise: (i) Nuclear and organellar genomes differ ...
Basic reading, writing and informatics skills for biomedical research
... The morphological properties of each word/phrase, e.g., what type of plural does it take, what type of past tense, how does it combine with affixes like "re" and "ation"; How to disambiguate word senses - This allows Cognition's technology to pick the correct word meaning of ambiguous words in conte ...
... The morphological properties of each word/phrase, e.g., what type of plural does it take, what type of past tense, how does it combine with affixes like "re" and "ation"; How to disambiguate word senses - This allows Cognition's technology to pick the correct word meaning of ambiguous words in conte ...
Biophysics 101 Genomics and Computational Biology
... A mutant Escherichia coli sigma 70 subunit of RNA polymerase with altered promoter specificity. A mutant of Escherichia coli with altered inducer specificity for the fad regulon. A mutation in the xanthine dehydrogenase (purine hydroxylase I) of Aspergillus nidulans resulting in altered specificity. ...
... A mutant Escherichia coli sigma 70 subunit of RNA polymerase with altered promoter specificity. A mutant of Escherichia coli with altered inducer specificity for the fad regulon. A mutation in the xanthine dehydrogenase (purine hydroxylase I) of Aspergillus nidulans resulting in altered specificity. ...
Section 3: Prokaryotic Sample and Array Processing
... This chapter describes the assay procedures recommended for use with the GeneChip® P. aeruginosa Genome Array and the GeneChip∆ E. coli Antisense Genome Array. The assay utilizes reverse transcriptase and random hexamer primers to produce DNA complementary to the RNA. The cDNA products are then frag ...
... This chapter describes the assay procedures recommended for use with the GeneChip® P. aeruginosa Genome Array and the GeneChip∆ E. coli Antisense Genome Array. The assay utilizes reverse transcriptase and random hexamer primers to produce DNA complementary to the RNA. The cDNA products are then frag ...
Conservation of Brachyury (T) genes in amphioxus and vertebrates
... sequence identity throughout their coding regions (94% amino acid identity over 444 sites), but differ markedly over their 5′ and 3′ untranslated regions (UTRs). The lengths of the 3′ UTRs are also quite different, being 825 nt for AmBra-1 and 377 nt for AmBra-2 (excluding stop codon and terminal A ...
... sequence identity throughout their coding regions (94% amino acid identity over 444 sites), but differ markedly over their 5′ and 3′ untranslated regions (UTRs). The lengths of the 3′ UTRs are also quite different, being 825 nt for AmBra-1 and 377 nt for AmBra-2 (excluding stop codon and terminal A ...
Wolbachia – a Heritable Endosymbiont
... In Adalia bipunctata and Acraea encedon the presence of Wolbachia halves the hatch size and changes the female/male ratio Microbial nature of infection has been verified by treatment with rifampin and sulphamethoxazole After treatment with antibiotics the hatch size returns to normal and the with a ...
... In Adalia bipunctata and Acraea encedon the presence of Wolbachia halves the hatch size and changes the female/male ratio Microbial nature of infection has been verified by treatment with rifampin and sulphamethoxazole After treatment with antibiotics the hatch size returns to normal and the with a ...
Genome evolution
Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.