The Interplay of Temperature and Genotype on Patterns
... Temperature is one of the key environmental parameters, in particular for ectotherms such as Drosophila. A broad range of morphological, behavioral, and physiological responses to temperature has been described, but few studies attempted to compare the patterns of gene expression plasticity across t ...
... Temperature is one of the key environmental parameters, in particular for ectotherms such as Drosophila. A broad range of morphological, behavioral, and physiological responses to temperature has been described, but few studies attempted to compare the patterns of gene expression plasticity across t ...
Microarray-based comparative genomic hybridisation (array CGH)
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
... (where a section of a chromosome is inverted or reversed), will not be identified using array CGH. This is because balanced chromosome rearrangements do not result in any loss or gain of chromosome material. It will also not detect some types of polyploidy (more than the usual 2 sets of chromosomes) ...
Sex-specific Trans-regulatory Variation on the Drosophila melanogaster X Chromosome
... genes with expression that shows a high degree of sexually discordant genetic variation (SDV genes, n = 121), and another set of genes that shows a high degree of sexually concordant genetic variation (SCV genes, n = 151) (S1 Fig.; S1 Table). SDV and SCV genes were evenly distributed, with respect t ...
... genes with expression that shows a high degree of sexually discordant genetic variation (SDV genes, n = 121), and another set of genes that shows a high degree of sexually concordant genetic variation (SCV genes, n = 151) (S1 Fig.; S1 Table). SDV and SCV genes were evenly distributed, with respect t ...
Topic B5 Genes, inheritance and selection
... will engage well with given the correct context. If delivered in the abstract, learners will struggle to engage with the topic and so it is best delivered in context. There are numerous opportunities to do this, for example through the use of celebrity families and the analysis of visual traits. Lea ...
... will engage well with given the correct context. If delivered in the abstract, learners will struggle to engage with the topic and so it is best delivered in context. There are numerous opportunities to do this, for example through the use of celebrity families and the analysis of visual traits. Lea ...
word
... dosage compensation, including X inactivation and X up-regulation. We have previously shown that the mammalian X chromosome is up-regulated two-fold to balance expression between X-linked genes and autosomal genes. Pseudoautosomal genes are not up-regulated, as expected for genes with equivalent cop ...
... dosage compensation, including X inactivation and X up-regulation. We have previously shown that the mammalian X chromosome is up-regulated two-fold to balance expression between X-linked genes and autosomal genes. Pseudoautosomal genes are not up-regulated, as expected for genes with equivalent cop ...
The Human Genome Project: Genetic Screening and the
... (T), and Cystosine (C).'" There are two sets of the chain-base combination, and the bases from each chain attract each other and always pair up in the exact same way: (A) always pairs with (T), and (G) always pairs with (C). As the bases pair up, the chains wrap around one another, thus forming the ...
... (T), and Cystosine (C).'" There are two sets of the chain-base combination, and the bases from each chain attract each other and always pair up in the exact same way: (A) always pairs with (T), and (G) always pairs with (C). As the bases pair up, the chains wrap around one another, thus forming the ...
development, the Linker histone H1 is essential for Drosophila
... a genetically tractable organism where H1 may prove to play an essential role. As mentioned, deletion of the yeast HHO1 gene does not lead to obvious phenotypic effects. Although linker histones are essential for embryonic development in mice, the existence of multiple, nonallelic mouse H1 variant g ...
... a genetically tractable organism where H1 may prove to play an essential role. As mentioned, deletion of the yeast HHO1 gene does not lead to obvious phenotypic effects. Although linker histones are essential for embryonic development in mice, the existence of multiple, nonallelic mouse H1 variant g ...
Databases_what_and_w..
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
... come from the DNA via RNA. • Changes in DNA cause changes in proteins. • Changes in proteins cause changes in phenotypes. ...
Characteristics of a Laboratory Strain of Coleomegilla maculata with
... Insects were maintained as previously described [2] [3]. Individual insects were isolated for reciprocal straincrosses, and putative heterozygous first generation offspring (F1) crosses were pooled. Observed phenotype data were collected and entered into a spreadsheet, and phenotypic ratios were com ...
... Insects were maintained as previously described [2] [3]. Individual insects were isolated for reciprocal straincrosses, and putative heterozygous first generation offspring (F1) crosses were pooled. Observed phenotype data were collected and entered into a spreadsheet, and phenotypic ratios were com ...
Analyses of the E3 ubiquitin-ligase target adapter
... from land plants and Chlamydomonas (MATH-BTB and ARM-BTB), most of the architectures found in Chlamydomonas (e.g. BTB-SBP, NHL-BTB) are not seen in land plants and vice-versa. •There is significant sequence diversity within the collection of Chlamydomonas BTB domains. This is similar to the BTB doma ...
... from land plants and Chlamydomonas (MATH-BTB and ARM-BTB), most of the architectures found in Chlamydomonas (e.g. BTB-SBP, NHL-BTB) are not seen in land plants and vice-versa. •There is significant sequence diversity within the collection of Chlamydomonas BTB domains. This is similar to the BTB doma ...
Lesson Overview
... For example, humans have three genes responsible for color vision, all located on the X chromosome. In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males ...
... For example, humans have three genes responsible for color vision, all located on the X chromosome. In males, a defective allele for any of these genes results in colorblindness, an inability to distinguish certain colors. The most common form, red-green colorblindness, occurs in about 1 in 12 males ...
The Limits of Natural Selection in a
... the strength of selection. Elevated dN/dS values are often interpreted as reflecting reduced efficacy of negative selection, but elevated dN/dS can also indicate elevated positive selection [48,82]. In addition, because new mutations accumulate slowly, we expect only modest differences in the number o ...
... the strength of selection. Elevated dN/dS values are often interpreted as reflecting reduced efficacy of negative selection, but elevated dN/dS can also indicate elevated positive selection [48,82]. In addition, because new mutations accumulate slowly, we expect only modest differences in the number o ...
Genetic architecture and balancing selection: the life
... We here focus on the mechanisms by which several functional variants for a given trait can arise, a process typically requiring multiple epistatic mutations. We highlight how balancing selection can favour specific features in the genetic architecture and review the evolutionary and molecular mechan ...
... We here focus on the mechanisms by which several functional variants for a given trait can arise, a process typically requiring multiple epistatic mutations. We highlight how balancing selection can favour specific features in the genetic architecture and review the evolutionary and molecular mechan ...
QSTAR - Institute of Bioinformatics
... (2015). Using transcriptomics to guide lead optimization in drug discovery projects. ...
... (2015). Using transcriptomics to guide lead optimization in drug discovery projects. ...
Probing the evolution of appendage specialization by
... in the body of diverse animals (1), and changes in Hox gene function have been linked to the evolution of animal body plans. For example, changes in Hox gene regulation (2–6), in Hox coding sequences (7, 8), and in the interactions of Hox genes with their downstream targets (9, 10) have all been imp ...
... in the body of diverse animals (1), and changes in Hox gene function have been linked to the evolution of animal body plans. For example, changes in Hox gene regulation (2–6), in Hox coding sequences (7, 8), and in the interactions of Hox genes with their downstream targets (9, 10) have all been imp ...
Gene quantification using real-time quantitative PCR
... DNA copy number measurements are important in determining the extent of genomic imbalance that underlies most malignancies. There are numerous techniques available for measuring DNA copy number in tumors; each method has specific advantages and disadvantages. Chromosomal CGH can detect imbalances ac ...
... DNA copy number measurements are important in determining the extent of genomic imbalance that underlies most malignancies. There are numerous techniques available for measuring DNA copy number in tumors; each method has specific advantages and disadvantages. Chromosomal CGH can detect imbalances ac ...
Polyploidy Enhances F Pollen Sterility Loci
... interactions between pollen sterility loci during pollen mother cell (PMC) meiosis in intersubspecific autotetraploid rice hybrids. Microarray and RNA sequencing (RNA-Seq)-based transcriptome profiling are helpful tools for characterizing molecular aspects of male and female gametophyte development in ...
... interactions between pollen sterility loci during pollen mother cell (PMC) meiosis in intersubspecific autotetraploid rice hybrids. Microarray and RNA sequencing (RNA-Seq)-based transcriptome profiling are helpful tools for characterizing molecular aspects of male and female gametophyte development in ...
SNP Set Analysis for Detecting Disease Association Using Exon
... (FWER). A gene is then said to be selected by a method, if its corresponding adjusted p-value is less than 0.1. Throughout the 100 pairs of screening and test data sets, if threshold 0.1 is used in the screening step, then four genes (FLT1, PIK3C3, KDR, PRR4) are selected for more than 10 times by a ...
... (FWER). A gene is then said to be selected by a method, if its corresponding adjusted p-value is less than 0.1. Throughout the 100 pairs of screening and test data sets, if threshold 0.1 is used in the screening step, then four genes (FLT1, PIK3C3, KDR, PRR4) are selected for more than 10 times by a ...
Exam 2
... recipient(s) and how you would select for recombinants.] Using potential deletion as a recipient, test recombination with donors which have point mutations in different intervals of the putP gene, selecting for PutP+ phenotype. d. Some deletion intervals contain many point mutations but some deletio ...
... recipient(s) and how you would select for recombinants.] Using potential deletion as a recipient, test recombination with donors which have point mutations in different intervals of the putP gene, selecting for PutP+ phenotype. d. Some deletion intervals contain many point mutations but some deletio ...
WW Genetic Counselor English - Wonderwise
... genetic counselor. Cathy works in a hospital clinic, where she sees people of all ages. Adults and kids visit her with different kinds of health problems that might be passed on from one generation to the next. You probably know that we inherit features such as our hair or eye color from our parents ...
... genetic counselor. Cathy works in a hospital clinic, where she sees people of all ages. Adults and kids visit her with different kinds of health problems that might be passed on from one generation to the next. You probably know that we inherit features such as our hair or eye color from our parents ...
Adherin - Semantic Scholar
... how the adherin proteins (Table 1) regulate diverse chromosomal functions and development. Adherin functions were originally revealed by genetic mutations in fungi: the rad9-1 adherin mutant of the mushroom Coprinus cinereus is defective in meiotic DNA repair, chromatid cohesin and homolog pairing [ ...
... how the adherin proteins (Table 1) regulate diverse chromosomal functions and development. Adherin functions were originally revealed by genetic mutations in fungi: the rad9-1 adherin mutant of the mushroom Coprinus cinereus is defective in meiotic DNA repair, chromatid cohesin and homolog pairing [ ...
Brassinosteroid-6-Oxidases from Arabidopsis and
... the same gene, but only F5F3 had sufficient length to contain the full-length cDNA (data not shown). When the entire nucleotide sequence of the cDNA insert of F5F3 was determined and compared with the Dwarf gene, it was apparent that the first intron remained un-spliced with the consensus splice sit ...
... the same gene, but only F5F3 had sufficient length to contain the full-length cDNA (data not shown). When the entire nucleotide sequence of the cDNA insert of F5F3 was determined and compared with the Dwarf gene, it was apparent that the first intron remained un-spliced with the consensus splice sit ...
Evolutionary ecology of rotifers - with emphasis on life
... There are strong mechanistic links between the life histories of individuals and population growth, and a rich theoretical population biology theory formalizes these connections. For example, matrix population models are defined on the age-specific (or stage-specific) schedules of survival and repro ...
... There are strong mechanistic links between the life histories of individuals and population growth, and a rich theoretical population biology theory formalizes these connections. For example, matrix population models are defined on the age-specific (or stage-specific) schedules of survival and repro ...
Genomic organisation of the Mal d 1 gene cluster on linkage group
... in Mal d 1 isoallergens that are not expressed in fruit and, thus, are not involved in allergic reactions. The observed functional differentiation among isoallergens and variants suggests the need for in-depth knowledge about the existence and performance of individual proteins and, thus, of individ ...
... in Mal d 1 isoallergens that are not expressed in fruit and, thus, are not involved in allergic reactions. The observed functional differentiation among isoallergens and variants suggests the need for in-depth knowledge about the existence and performance of individual proteins and, thus, of individ ...
Genome evolution
Genome evolution is the process by which a genome changes in structure (sequence) or size over time. The study of genome evolution involves multiple fields such as structural analysis of the genome, the study of genomic parasites, gene and ancient genome duplications, polyploidy, and comparative genomics. Genome evolution is a constantly changing and evolving field due to the steadily growing number of sequenced genomes, both prokaryotic and eukaryotic, available to the scientific community and the public at large.