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chakravartiLab
chakravartiLab

... Use chip data first in linkage study, then use same data with transmission-disequilibrium-test for association study within candidate regions. • Have found some relatively common varients that contribute to risk. • Colleagues at UCLA have found rarer, higher risk variants. ...
HIV Vaccine Database and Web Works
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why don`t identical twins have identical fingerprints?
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... Because the physical appearance of twins are the same, you might expect that his fingerprints identical too. But it is not so. ...
Etiology and Pathogenesis of Depressive Disorders
Etiology and Pathogenesis of Depressive Disorders

... has no contribution whatever, genetic factors account for around 40% of the variance, and environment unique to the individual accounts for a large part of the rest. ...
Statistical Genetics
Statistical Genetics

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Genetic determination of yield related attributes in Brassica napus
Genetic determination of yield related attributes in Brassica napus

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Sample Chapter 3 (PDF, 30 Pages

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Getting to Know: Genes
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... Misconception 2: Our traits change as we grow older because we take in new genes from the environment over time. That’s not correct. People’s traits do change as they age, but this is not a result of genes changing. In fact, we have the same genes for our entire lives. Changes that occur with aging ...
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Heritability of IQ

Research on heritability of IQ infers from the similarity of IQ in closely related persons the proportion of variance of IQ among individuals in a study population that is associated with genetic variation within that population. This provides a maximum estimate of genetic versus environmental influence for phenotypic variation in IQ in that population. ""Heritability"", in this sense, ""refers to the genetic contribution to variance within a population and in a specific environment"". There has been significant controversy in the academic community about the heritability of IQ since research on the issue began in the late nineteenth century. Intelligence in the normal range is a polygenic trait. However, certain single gene genetic disorders can severely affect intelligence, with phenylketonuria as an example.Estimates in the academic research of the heritability of IQ have varied from below 0.5 to a high of 0.8 (where 1.0 indicates that monozygotic twins have no variance in IQ and 0 indicates that their IQs are completely uncorrelated). Some studies have found that heritability is lower in families of low socioeconomic status. IQ heritability increases during early childhood, but it is unclear whether it stabilizes thereafter. A 1996 statement by the American Psychological Association gave about 0.45 for children and about .75 during and after adolescence. A 2004 meta-analysis of reports in Current Directions in Psychological Science gave an overall estimate of around 0.85 for 18-year-olds and older. The general figure for heritability of IQ is about 0.5 across multiple studies in varying populations. Recent studies suggest that family environment (i.e., upbringing) has negligible long-lasting effects upon adult IQ.
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