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Population Genetics
Population Genetics

... has reduced the fraction from 25% to 11% in one generation. It would further reduce the fraction each generation, but since there are fewer of them, fewer would be selected against, as well. N.B. natural selection - acts on phenotypes - selects only among variants present Natural selection acts on p ...
Population genetics and microevolution
Population genetics and microevolution

... Where does the variation come from? Ultimately, all genetic variation in living organisms originates as mutations. The variation we observe in a population is also determined by: 1) recombination (sexual reproduction) 2) the spread of variants in a population due to drift, and 3) the effects of envi ...
2-Slides
2-Slides

... Originally only one sex (asexual reproduction … cloning_..) mitosis ~ complete inheritance > 1 sex ? ...
Document
Document

... developmental fate of cells in multicellular organisms. • Developmental pathways consist of sequences of various regulatory steps. • The zygote is totipotent, giving rise to all body cells. • Gradients of maternally-derived regulatory proteins establish polarity of the body axis and control transcri ...
Inheritance-Act-1-3
Inheritance-Act-1-3

... • If it is dominant it gets the capital letter and if it is recessive it gets the lower case of the same letter. • E.g. in pea plants tall is dominant over dwarf, and so the tall allele is given the letter T, and the dwarf allele the letter t. • The genotype of the organism is the alleles it carrie ...
Supplementary Information (doc 46K)
Supplementary Information (doc 46K)

... produced a better hit that was not annotated. The tblastx hits have no Bombyx ...
Chapter 14 - River Ridge #210
Chapter 14 - River Ridge #210

... 4. As a result, blood stops moving through these vessels, damaging cells, tissues and organs. ...
Isochores and Genes: Who`s in the Driver`s Seat?
Isochores and Genes: Who`s in the Driver`s Seat?

... Where does this project need to go? • The basic hypothesis is that exposure to chromosome ends “causes” most (but not all) genes to become CG rich – maybe (1st approximation) in proportion to the exposure time? – can weakly predict, by function, the genes that don’t ...
PCR Lab Notes
PCR Lab Notes

... These genes only comprise about 5 % of chromosomal DNA. The other 95% is non-coding DNA. The sequence with the genes are introns, which is transcribed into RNA but in the end do not make a protein. ...
Further thoughts on the Challenges of Darwinism
Further thoughts on the Challenges of Darwinism

... lateral transfer of genetic material between single-celled organisms. The exchange occurs between two organisms living simultaneously, not successively; regarding the latter, traditional mechanism of gene transfer as “vertical”, the newly-described process was termed “hor ...
Human Heredity
Human Heredity

... 4. As a result, blood stops moving through these vessels, damaging cells, tissues and organs. ...
Estrogen
Estrogen

... One clear problem in analysing transcriptomic data is that we are usually presented with a list of 100’s of genes that are clearly differentially expressed in a particular experiment. The question now is what biological conclusions can we draw from this data ? The most widely used approach (apart f ...
Gene Regulation Powerpoint[1]
Gene Regulation Powerpoint[1]

... body mass personality traits (at least many traits) diabetes asthma schizophrenia ...
Summary:A Neural Substrate of Prediction and Reward
Summary:A Neural Substrate of Prediction and Reward

... of action followed by change in state and reward goes on until the episode ends. An agent learns a “policy” , which is a mapping (probabilistic or deterministic) from the state space to action space i.e. what action to perform , given a state . For example, for an agent in the 2-D world whose aim is ...
Gene List Enrichment Analysis
Gene List Enrichment Analysis

... Most cellular processes involve sets of genes. M t ll l i l t f Can we compare the above two datasets? p Is the overlap different than expected? D Does this tell us something about cellular  hi ll hi b ll l mechanisms? ...
Due
Due

... - Read the first paragraph and complete Stop & Think questions 1-3 as a class - Independently and quietly finish reading and complete stop & think questions 4-10. ...
Epigenetics seminar 9-7-2014
Epigenetics seminar 9-7-2014

... variants had a 23% higher risk of obesity than those who did not. But once again, being physically active lowered the risk by 30%. Genes are not destiny! •Another study of 38,759 Europeans for variants of FTO gene identified an obesity risk. •Carriers of 1 copy of the allele weighed on average 1.2 k ...
Body Axis Determination in Birds and Mammals
Body Axis Determination in Birds and Mammals

... get anterior transformations just like flies, indicating that posterior genes inhibit anterior. Good direct evidence. ! Eg. Knockout mouse Hoxc-8 converts a lumbar vertebra to a thoracic vertebra#get extra rib 2. Retinoic Acid teratogenesis. [RA] is normally high in Hensen’s node and probably plays ...
Genes and Variatoin
Genes and Variatoin

... • Crossing over, also during meiosis. • Does not alter the relative frequencies of each type of allele in a population ...
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate
Pre-natal Orofacial Development - Causes of Cleft Lip and Cleft Palate

... bone (bone of roof of the mouth) that forms the palatal shelves do not come together and fuse. This disruption of the palatal shelving could also cause the soft palate of the mesenchymal cells to not fuse as well. Palatogenesis is usually complete by week twelve. Some classes of genes involved in cr ...
The genotype-phenotype relationship homologies, convergences
The genotype-phenotype relationship homologies, convergences

... Candidate gene ...
P0196 Poster Session I Basic science: pathogenesis of
P0196 Poster Session I Basic science: pathogenesis of

... an analogical quantification of individual genes transcription (via the fluorescent intensity measuring the amount of hybridization between capture probes and their complementary cDNA fragments), RNA-seq methods make it possible to get a comprehensive digital quantification of transcribed regions (a ...
Activity 2 Is It Heredity or the Environment?
Activity 2 Is It Heredity or the Environment?

... example, human beings may have blond, red, brown, or black hair.They may have tongues that they can roll or not roll. (Try it! Can you roll your tongue? Can your parents?) They may have earlobes that are attached or free.The passing of traits from parents to offspring is called heredity. In most org ...
Sex Linked Genes
Sex Linked Genes

... Sex linked genes generally show up more in one sex than the other What are some examples of conditions or characteristics that show up more regularly in females or males? ...
Lesson 4 and 5 Notes
Lesson 4 and 5 Notes

...  Alleles- different versions of the gene (G- dominant, g- recessive)  Heterozygous- trait is one dominant and 1 recessive allele (Gg)  Homozygous- trait is two dominant or 2 recessive alleles (GG or gg) o Genes influence traits  Genotype- combination of alleles (genes) you inherit (GG, Gg, or gg ...
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Biology and consumer behaviour

Consumer behaviour is the study of the motivations surrounding a purchase of a product or service. It has been linked to the field of psychology, sociology and economics in attempts to analyse when, why, where and how people purchase in the way that they do. However, little literature has considered the link between our consumption behaviour and the basics of our being, our biology. Segmentation by biological driven demographics such as sex and age are already popular and pervasive in marketing. As more knowledge and research is known, targeting based on a consumers biology is of growing interest and use to marketers.As human machines being made up of cells controlled by our brain to influence aspects of our behaviour, there must be some influence of biology on our consumer behaviour and how we purchase as well. The nature versus nurture debate is at the core of how much biology influences these buying decisions, because it argues the extent to which biological factors influence what we do, and how much is reflected through environmental factors. Neuromarketing is of interest to marketers in measuring the reaction of stimulus to marketing. Even though we know there is a reaction, the question of why we consume the way we do still lingers, but it is a step in the right direction. Biology helps to understand consumer behaviour as it influences consumption and aids in the measurement of it.Lawson and Wooliscroft (2004) drew the link between human nature and the marketing concept, not explicitly biology, where they considered the contrasting views of Hobbes and Rousseau on mankind. Hobbes believed man had a self-serving nature whereas Rousseau was more forgiving towards the nature of man, suggesting them to be noble and dignified. Hobbes saw the need for a governing intermediary to control this selfish nature which provided a basis for the exchange theory, and also links to Mcgregor’s Theory of X and Y, relevant to management literature. He also considered cooperation and competition, relevant to game theory as an explanation of man’s motives and can be used for understanding the exercising of power in marketing channels. Pinker outlines why the nature debate has been suppressed by the nurture debate in his book The Blank Slate.
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