Network medicine - a network
... Owing to the conservation of biochemical and molecular functions across species, much of our current understanding of cellular networks is derived from model organisms. Yet, in the past decade we witnessed an exceptional growth in human-specific molecular interaction data, helping us understand the ...
... Owing to the conservation of biochemical and molecular functions across species, much of our current understanding of cellular networks is derived from model organisms. Yet, in the past decade we witnessed an exceptional growth in human-specific molecular interaction data, helping us understand the ...
zygon
... either its form or its informational content. Memes with low informational content, such as simple propositions, may be considered analogous to nucleotides. At the other extreme, large integrated complexes of memes, such as religions, are analogous to genomes. This hierarchical structuring of the me ...
... either its form or its informational content. Memes with low informational content, such as simple propositions, may be considered analogous to nucleotides. At the other extreme, large integrated complexes of memes, such as religions, are analogous to genomes. This hierarchical structuring of the me ...
Gene Section DLX6 (distal-less homeobox 6) Atlas of Genetics and Cytogenetics
... controlling DLX5/DLX6 activity are involved in the pathogenesis of this developmental disorder (see further "dysmorphologies"). In-depth sequencing of the candidate regions has shown that the expression of DLX6 depends upon the activity of conserved regulatory elements shared with DLX5, and located ...
... controlling DLX5/DLX6 activity are involved in the pathogenesis of this developmental disorder (see further "dysmorphologies"). In-depth sequencing of the candidate regions has shown that the expression of DLX6 depends upon the activity of conserved regulatory elements shared with DLX5, and located ...
molecular approaches in natural resource conservation
... from the University of Dayton and his PhD in zoology from Texas Tech University. He was on the faculty of Texas A&M University’s Department of Wildlife and Fisheries Sciences for thirty years. He has published more than two hundred articles in scientific journals in evolutionary genetics, including ...
... from the University of Dayton and his PhD in zoology from Texas Tech University. He was on the faculty of Texas A&M University’s Department of Wildlife and Fisheries Sciences for thirty years. He has published more than two hundred articles in scientific journals in evolutionary genetics, including ...
Elke Winterhager (Ed.) Gap Junctions in Development
... be mediated via protein–protein interactions at the C-terminus of the connexin. Thus, there is a need to discriminate between channel and protein function. Impairment of development and diseases need not be based on connexin mutations, but rather on wrong signaling mediated via protein– protein inte ...
... be mediated via protein–protein interactions at the C-terminus of the connexin. Thus, there is a need to discriminate between channel and protein function. Impairment of development and diseases need not be based on connexin mutations, but rather on wrong signaling mediated via protein– protein inte ...
CURRICULUM VITAE
... Burdman S and Walcott R. 2012. Acidovorax citrulli: generating basic and applied knowledge to tackle a global threat to the cucurbit industry. Molecular Plant Pathology 13:805-815. Tamir-Ariel D, Rosenberg T, Navon N and Burdman S. 2012. A secreted lipolytic enzyme from Xanthomonas campestris pv. ve ...
... Burdman S and Walcott R. 2012. Acidovorax citrulli: generating basic and applied knowledge to tackle a global threat to the cucurbit industry. Molecular Plant Pathology 13:805-815. Tamir-Ariel D, Rosenberg T, Navon N and Burdman S. 2012. A secreted lipolytic enzyme from Xanthomonas campestris pv. ve ...
Excess of Deleterious Mutations around HLA
... Deleterious mutations are expected to evolve under negative selection and are usually purged from the population. However, deleterious alleles segregate in the human population and some disease-associated variants are maintained at considerable frequencies. Here, we test the hypothesis that balancin ...
... Deleterious mutations are expected to evolve under negative selection and are usually purged from the population. However, deleterious alleles segregate in the human population and some disease-associated variants are maintained at considerable frequencies. Here, we test the hypothesis that balancin ...
A Twist-like bHLH gene is a downstream factor of an
... 2002). In the present study, we use the term ‘mesenchyme’ for all of these cells, except where indicated otherwise. In addition to these three lineages of mesenchymal cells, ascidian larvae develop trunk ventral cells (TVCs), which are often regarded as a kind of mesenchymal cell because they give r ...
... 2002). In the present study, we use the term ‘mesenchyme’ for all of these cells, except where indicated otherwise. In addition to these three lineages of mesenchymal cells, ascidian larvae develop trunk ventral cells (TVCs), which are often regarded as a kind of mesenchymal cell because they give r ...
transgenic canola - Australian Oilseeds Federation
... The environmental safety of any new product must be demonstrated to GMAC before field release is approved. Issues of critical importance to be addressed in canola include the likelihood of the GMOs, especially herbicide tolerant GMOs, becoming more weedy in their own right, the likelihood of the her ...
... The environmental safety of any new product must be demonstrated to GMAC before field release is approved. Issues of critical importance to be addressed in canola include the likelihood of the GMOs, especially herbicide tolerant GMOs, becoming more weedy in their own right, the likelihood of the her ...
PDF + SI - Biology Open - The Company of Biologists
... identification and mapping of yellow seed coat gene, as well as associated inheritance studies, are important steps in breeding yellow seed germplasm. The inheritance of yellow seeds has been studied for a long time in Brassica. Here, the segregation of brown- and yellow-seeded individuals in an F2 ...
... identification and mapping of yellow seed coat gene, as well as associated inheritance studies, are important steps in breeding yellow seed germplasm. The inheritance of yellow seeds has been studied for a long time in Brassica. Here, the segregation of brown- and yellow-seeded individuals in an F2 ...
7. Rh Blood Group System - Austin Community College
... Individuals who lack the D antigen do not have anti-D in their serum. b. The antibody is produced through exposure to the D antigen usually as a result of transfusion or pregnancy. c. The immunogenicity (ability of antigen to stimulate production of antibody) of D is greater than that of virtually a ...
... Individuals who lack the D antigen do not have anti-D in their serum. b. The antibody is produced through exposure to the D antigen usually as a result of transfusion or pregnancy. c. The immunogenicity (ability of antigen to stimulate production of antibody) of D is greater than that of virtually a ...
Hox Targets and Cellular Functions
... the first work [54], the authors found 2 genes differentially expressed in T1 and T3 leg discs, 12 when comparing T2 and T3 discs and 17 in T1 and T2 discs. In the second study [61], the authors focused their analysis on the genes specifically expressed in the T1 leg disc. This disc, the only one re ...
... the first work [54], the authors found 2 genes differentially expressed in T1 and T3 leg discs, 12 when comparing T2 and T3 discs and 17 in T1 and T2 discs. In the second study [61], the authors focused their analysis on the genes specifically expressed in the T1 leg disc. This disc, the only one re ...
PART ONE - flickbio
... 1. Pick up two index cards: an “A” card and an “a” card. This means that everyone starts out heterozygous (Aa). 2. Find your first partner and mate to make your first offspring. 3. The offspring are made by randomly selecting one card from each person. The resulting baby will have a genotype based o ...
... 1. Pick up two index cards: an “A” card and an “a” card. This means that everyone starts out heterozygous (Aa). 2. Find your first partner and mate to make your first offspring. 3. The offspring are made by randomly selecting one card from each person. The resulting baby will have a genotype based o ...
PDF
... (Hanisch et al., 2013; Schroter et al., 2012; Trofka et al., 2012). Furthermore, these models focused on simulating the system only in a wild-type background and were therefore largely unconstrained. More rigorous models can be built by constraining them to explain the spatiotemporal dynamics of the ...
... (Hanisch et al., 2013; Schroter et al., 2012; Trofka et al., 2012). Furthermore, these models focused on simulating the system only in a wild-type background and were therefore largely unconstrained. More rigorous models can be built by constraining them to explain the spatiotemporal dynamics of the ...
Obtaining genetic testing in pediatric epilepsy
... X-linked infantile spasms (CDKL5 and ARX) Mutations in CDKL5 are inherited in an X-linked dominant fashion and are a common cause of infantile spasms (IS) and early onset seizures. CDKL5 is responsible for 8% of early onset seizures (<9 months) in girls and 28% of early onset seizures with infantile ...
... X-linked infantile spasms (CDKL5 and ARX) Mutations in CDKL5 are inherited in an X-linked dominant fashion and are a common cause of infantile spasms (IS) and early onset seizures. CDKL5 is responsible for 8% of early onset seizures (<9 months) in girls and 28% of early onset seizures with infantile ...
Cnidarians and the evolutionary origin of the nervous system Review
... patterns of Wnt genes and their antagonists, which may indicate that the bilaterian trunk was intercalated between the oral and aboral body region (Meinhardt 2002; Guder et al. 2006a, 2006b). New expression studies in cnidarian species, however, reveal a more complex situation. The expression patter ...
... patterns of Wnt genes and their antagonists, which may indicate that the bilaterian trunk was intercalated between the oral and aboral body region (Meinhardt 2002; Guder et al. 2006a, 2006b). New expression studies in cnidarian species, however, reveal a more complex situation. The expression patter ...
Recombination and epistasis facilitate introgressive hybridization
... relevance of the random gamete assumption, I conducted individual-based simulations, which were free from the random gamete assumption. Random gamete model In the process of introgressive hybridization, linkage disequilibrium may be important in affecting hybridization, because linkage equilibrium i ...
... relevance of the random gamete assumption, I conducted individual-based simulations, which were free from the random gamete assumption. Random gamete model In the process of introgressive hybridization, linkage disequilibrium may be important in affecting hybridization, because linkage equilibrium i ...
A gene expression atlas of a bicoid-depleted
... biochemical analysis in future work. The second problem, phenotypic variation, is shared by shRNA depletion and mutant alleles (Waddington, 1942). We reduced variability both experimentally and by curating our images so that the resulting atlas represents the most common phenotypic class. Both of th ...
... biochemical analysis in future work. The second problem, phenotypic variation, is shared by shRNA depletion and mutant alleles (Waddington, 1942). We reduced variability both experimentally and by curating our images so that the resulting atlas represents the most common phenotypic class. Both of th ...
WGCNA: an R package for weighted correlation network analysis
... for calculating module membership measures. Correlation networks facilitate network based gene screening methods that can be used to identify candidate biomarkers or therapeutic targets. These methods have been successfully applied in various biological contexts, e.g. cancer, mouse genetics, yeast g ...
... for calculating module membership measures. Correlation networks facilitate network based gene screening methods that can be used to identify candidate biomarkers or therapeutic targets. These methods have been successfully applied in various biological contexts, e.g. cancer, mouse genetics, yeast g ...
Adaptation and Inclusive Fitness - Department of Zoology, University
... Stuart A. West1,* and Andy Gardner1,2 ...
... Stuart A. West1,* and Andy Gardner1,2 ...
Lesson Overview
... Mendel’s principles of heredity, observed through patterns of inheritance, form the basis of modern genetics. ...
... Mendel’s principles of heredity, observed through patterns of inheritance, form the basis of modern genetics. ...
Review Article
... The virulence of bacteria, their capacity to cause disease, is generally dependent on the expression of a variety of properties which create a complex series of interactions between the invading pathogen and a susceptible host. Different factors may be required at different stages of infection : ini ...
... The virulence of bacteria, their capacity to cause disease, is generally dependent on the expression of a variety of properties which create a complex series of interactions between the invading pathogen and a susceptible host. Different factors may be required at different stages of infection : ini ...
The genetics of obesity - National Genetics Education Centre
... Centre. Obesity and Genetics Factsheet. http://www.geneticseducation.nhs.uk/search/it em/29-0029-genetics-and-obesity • PHG Foundation. Genomics of Obesity: The Application of Public Health Genomics to the Prevention and Management of Obesity in the ...
... Centre. Obesity and Genetics Factsheet. http://www.geneticseducation.nhs.uk/search/it em/29-0029-genetics-and-obesity • PHG Foundation. Genomics of Obesity: The Application of Public Health Genomics to the Prevention and Management of Obesity in the ...
Daisy quorum drives for the genetic restoration of wild
... This manuscript is an example of pre-registration to ensure transparency in experimental gene drive research. It's intended as a “living document” that begins by sharing key concepts, rationale, and experimental plans for viewing and comment by the community before any experiments begin. As data are ...
... This manuscript is an example of pre-registration to ensure transparency in experimental gene drive research. It's intended as a “living document” that begins by sharing key concepts, rationale, and experimental plans for viewing and comment by the community before any experiments begin. As data are ...